Deep Learning Frameworks for Cardiovascular Arrhythmia Classification

Arrhythmia classification is a prominent research problem due to the computational complexities of learning the morphology of various ECG patterns and its wide prevalence in the medical field, particularly during the COVID-19 pandemic. In this article, we used Empirical Mode Decomposition and Discrete Wavelet Transform for preprocessing and then the modified signal is classified using various classifiers such as Decision Tree, Logistic Regression, Gaussian Naïve Bayes, Random Forest, Linear  SVM, Polynomial SVM, RBF SVM, Sigmoid SVM and Convolutional Neural Networks. The proposed method classify the data into five classes N (Normal), S (Supraventricular premature) beat, (V) Premature ventricular contraction, F (Fusion of ventricular and normal), and Q, (Unclassifiable Beat) using softmax regressor at the end of the network. The proposed approach performs well in terms of classification accuracy when tested using ECG signals acquired from the MIT-BIH database. In comparison to existing classifiers, the Accuracy, Precision, Recall, and F1 score values of the proposed technique are 98.5%, 96.9%, 94.3%, and 91.32%, respectively.  &nbsp

Algorithms for automated diagnosis of cardiovascular diseases based on ECG data: A comprehensive systematic review

The prevalence of cardiovascular diseases is increasing around the world. However, the technology is evolving and can be monitored with low-cost sensors anywhere at any time. This subject is being researched, and different methods can automatically identify these diseases, helping patients and healthcare professionals with the treatments. This paper presents a systematic review of disease identification, classification, and recognition with ECG sensors. The review was focused on studies published between 2017 and 2022 in different scientific databases, including PubMed Central, Springer, Elsevier, Multidisciplinary Digital Publishing Institute (MDPI), IEEE Xplore, and Frontiers. It results in the quantitative and qualitative analysis of 103 scientific papers. The study demonstrated that different datasets are available online with data related to various diseases. Several ML/DP-based models were identified in the research, where Convolutional Neural Network and Support Vector Machine were the most applied algorithms. This review can allow us to identify the techniques that can be used in a system that promotes the patient’s autonomy.N/

An Improved Firefly Optimization Algorithm for Analysis of Arrhythmia Types

Irregular heartbeats rhythm is the result of arrhythmia condition which can be a threat to life if not treated at the early stage. If it is necessary to know the type of arrhythmia to treat the patient appropriately. The traditional method is complex and an efficient algorithm is required to diagnose. An improved firefly optimization algorithm is proposed to analyze arrhythmia types. Four performance measures confirm the model's effectiveness and experimental evaluation shows that it achieves a sensitivity of 86.27%, accuracy of 86.14%, precision of 87.52%, and specificity of 87.37% in arrhythmia-type classification. The algorithm can effectively classify the arrhythmia types with high accuracy and specificity

Deep Learning in Cardiology

The medical field is creating large amount of data that physicians are unable to decipher and use efficiently. Moreover, rule-based expert systems are inefficient in solving complicated medical tasks or for creating insights using big data. Deep learning has emerged as a more accurate and effective technology in a wide range of medical problems such as diagnosis, prediction and intervention. Deep learning is a representation learning method that consists of layers that transform the data non-linearly, thus, revealing hierarchical relationships and structures. In this review we survey deep learning application papers that use structured data, signal and imaging modalities from cardiology. We discuss the advantages and limitations of applying deep learning in cardiology that also apply in medicine in general, while proposing certain directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table

Early Detection and Continuous Monitoring of Atrial Fibrillation from ECG Signals with a Novel Beat-Wise Severity Ranking Approach

Irregularities in heartbeats and cardiac functioning outside of clinical settings are often not available to the clinicians, and thus ignored. But monitoring these with high-risk population might assist in early detection and continuous monitoring of Atrial Fibrillation(AF). Wearable devices like smart watches and wristbands, which can collect Electrocardigraph(ECG) signals, can monitor and warn users of unusual signs in a timely manner. Thus, there is a need to develop a real-time monitoring system for AF from ECG. We propose an algorithm for a simple beat-by-beat ECG signal multilevel classifier for AF detection and a quantitative severity scale (between 0 to 1) for user feedback. For this study, we used ECG recordings from MIT BIH Atrial Fibrillation, MIT BIH Long-term Atrial Fibrillation Database. All ECG signals are preprocessed for reducing noise using filter. Preprocessed signal is analyzed for extracting 39 features including 20 of amplitude type and 19 of interval type. The feature space for all ECG recordings is considered for Classification. Training and testing data include all classes of data i.e., beats to identify various episodes for severity. Feature space from the test data is fed to the classifier which determines the class label based on trained model. A class label is determined based on number of occurences of AF and other arrhythmia episodes such as AB(Atrial Bigeminy), SBR(Sinus Bradycardia), SVTA(Supra Ventricular Tacchyarrhythmia). Accuracy of 96.7764% is attained with Random Forest algorithm, Furthermore, precision and recall are determined based on correct and incorrect classifications for each class. Precision and recall on average of Random Forest Classifier are obtained as 0.968 and 0.968 respectievely. This work provides a novel approach to enhance existing method of AF detection by identifying heartbeat class and calculates a quantitative severity metric that might help in early detection and continuous monitoring of AF

Deep Featured Adaptive Dense Net Convolutional Neural Network Based Cardiac Risk Prediction in Big Data Healthcare Environment

In recent days, cardiac vascular disease has been one of the deadliest health-affecting factors causing sudden death. So, the importance of early risk prediction through feature analysis has become a big problem in data analysis because more nonlinear time series data increase the feature dimension. Irrelevant feature dimension scaling affects the prediction accuracy and leads to classification inaccuracy. To resolve this problem, we propose an Enhanced Healthcare data analysis model for cardiac data prediction using an adaptive Deep Featured Adaptive Convolution Neural Network for early risk identification. Initially, the preprocessing was augmented to formalize the time series data collected from the CVD-DS dataset. Then the feature evaluation was carried out with the Relative Subset Clustering (RSC) approach. The Cardiac Deficiency Prediction rate (CDPr) was estimated to identify the relational feature to subset margins. Based on the CDPr weight the feature is extracted using Cross-Over Mutual Scaling Feature Selection Model (CMSFS). The selected features get with a deep neural classifier based on logical neurons. They are then constructed into a Dense Net Convolution Neural Network (DN-CNN) classifier to feed forward the feature values and predict the Disease Affection Rate (DAR) by class category. The proposed system produces high prediction accuracy in classification, precision, and recall rate to support premature treatment for early cardiac disease risk prediction.

Identification of myocardial infarction using consumer smartwatch ECG measurement

The goal of this thesis is to detect and classify acute myocardial infarctions from smartwatch ECG data. As the smartwatches have been increasing in numbers, and many of new smartwatch models have capability to detect ECG data. This study aims to answer to the question whether or not the ECG data from smartwatches can be used to detect acute myocardial infarctions. To answer to this question, and existing database has been used in tandem with smartwatch ECG data gathered from two different smartwatches. Five different machine learning models have been used to detect and classify ECG data. The best performing machine learning model was Extra Trees, which achieved accuracy of 90.84% with using Leave-One-Out Cross-Validation. These results show that ECG data from smartwatches could be used to detect infarctions. Measuring ECG with smartwatch is much easier than using clinical ECG measurement devices, meaning that ECG measuring could reach much wider audience that it has prior to this been able to reach. Further research could include gathering larger database from smartwatch ECG, and the data ownership of smartwatch, and other medical and biological data that companies collect

Recent Trends in Computational Research on Diseases

Recent advances in information technology have brought forth a paradigm shift in science, especially in the biology and medical fields. Statistical methodologies based on high-performance computing and big data analysis are now indispensable for the qualitative and quantitative understanding of experimental results. In fact, the last few decades have witnessed drastic improvements in high-throughput experiments in health science, for example, mass spectrometry, DNA microarray, next generation sequencing, etc. Those methods have been providing massive data involving four major branches of omics (genomics, transcriptomics, proteomics, and metabolomics). Information about amino acid sequences, protein structures, and molecular structures are fundamental data for the prediction of bioactivity of chemical compounds when screening drugs. On the other hand, cell imaging, clinical imaging, and personal healthcare devices are also providing important data concerning the human body and disease. In parallel, various methods of mathematical modelling such as machine learning have developed rapidly. All of these types of data can be utilized in computational approaches to understand disease mechanisms, diagnosis, prognosis, drug discovery, drug repositioning, disease biomarkers, driver mutations, copy number variations, disease pathways, and much more. In this Special Issue, we have published 8 excellent papers dedicated to a variety of computational problems in the biomedical field from the genomic level to the whole-person physiological level

Relationship between electrocardiogram‐based features and personality traits: Machine learning approach

Background: Based on the known relationship between the human emotion and standard surface electrocardiogram (ECG), we explored the relationship between features extracted from standard ECG recorded during relaxation and seven personality traits (Honesty/humility, Emotionality, eXtraversion, Agreeableness, Conscientiousness, Openness, and Disintegration) by using the machine learning (ML) approach which learns from the ECG-based features and predicts the appropriate personality trait by adopting an automated software algorithm. Methods: A total of 71 healthy university students participated in the study. For quantification of 62 ECG-based parameters (heart rate variability, as well as temporal and amplitude-based parameters) for each ECG record, we used computation procedures together with publicly available data and code. Among 62 parameters, 34 were segregated into separate features according to their diagnostic relevance in clinical practice. To examine the feature influence on personality trait classification and to perform classification, we used random forest ML algorithm. Results: Classification accuracy when clinically relevant ECG features were employed was high for Disintegration (81.3%) and Honesty/humility (75.0%) and moderate to high for Openness (73.3%) and Conscientiousness (70%), while it was low for Agreeableness (56.3%), eXtraversion (47.1%), and Emotionality (43.8%). When all calculated features were used, the classification accuracies were the same or lower, except for the eXtraversion (52.9%). Correlation analysis for selected features is presented. Conclusions: Results indicate that clinically relevant features might be applicable for personality traits prediction, although no remarkable differences were found among selected groups of parameters. Physiological associations of established relationships should be further explored.Ministry of Education, Science, and Technological Development, Republic of Serbia, Grant/Award Number: 179018 and TR33020; Abbott Laboratorie

Atrial fibrillation detection method based on converting ECG to signal using both symptoms of AF

Atrial Fibrillation (AF) is one of the most common cardiac arrhythmias that is associated with other kinds of cardiac cases including heart disease, risk of stroke and mortality [1]. The AF case has an irregular heartbeat and an asynchronous rate of the rhythm of the heart compared to the rate of the rhythm of heart of a healthy person. The objective of the research is to highlight AF as an important disease in today’s mortality cases and proposed an algorithm to detect AF by using all signs of it by converting Electrocardiogram (ECG) to signals. This paper proposed a statistical method of detecting AF which the techniques included analysis of consecutive RR intervals and detecting the existence or abnormal P wave. To verify the proposed method, the algorithm is tested over 100 pre-recorded ECGs of patients with healthy and AF conditions