Iterative criteria-based approach to engineering the requirements of software development methodologies

Software engineering endeavours are typically based on and governed by the requirements of the target software; requirements identification is therefore an integral part of software development methodologies. Similarly, engineering a software development methodology (SDM) involves the identification of the requirements of the target methodology. Methodology engineering approaches pay special attention to this issue; however, they make little use of existing methodologies as sources of insight into methodology requirements. The authors propose an iterative method for eliciting and specifying the requirements of a SDM using existing methodologies as supplementary resources. The method is performed as the analysis phase of a methodology engineering process aimed at the ultimate design and implementation of a target methodology. An initial set of requirements is first identified through analysing the characteristics of the development situation at hand and/or via delineating the general features desirable in the target methodology. These initial requirements are used as evaluation criteria; refined through iterative application to a select set of relevant methodologies. The finalised criteria highlight the qualities that the target methodology is expected to possess, and are therefore used as a basis for de. ning the final set of requirements. In an example, the authors demonstrate how the proposed elicitation process can be used for identifying the requirements of a general object-oriented SDM. Owing to its basis in knowledge gained from existing methodologies and practices, the proposed method can help methodology engineers produce a set of requirements that is not only more complete in span, but also more concrete and rigorous

Animals and Fungi are Each Other's Closest Relatives: Congruent Evidence from Multiple Proteins

Phylogenetic relationships among plants, animals, and fungi were examined by using sequences from 25 proteins. Four insertions/deletions were found that are shared by two of the three taxonomic groups in question, and all four are uniquely shared by animals and fungi relative to plants, protists, and bacteria. These include a 12-amino acid insertion in translation elongation factor la and three small gaps in enolase. Maximum-parsimony trees were constructed from published data for four of the most broadly sequenced of the 25 proteins, actin, a-tubulin, ,ß-tubulin, and elongation factor la, with the latter supplemented by three new outgroup sequences. All four proteins place animals and fungi together as a monophyletic group to the exclusion of plants and a broad diversity of protists. In all cases, bootstrap analyses show no support for either an animal-plant or hfngal-plant dade. This congruence among multiple lines of evidence strongly suggests, in contrast to traditional and current classification, that animals and fungi are sister groups while plants constitute an independent evolutionary lineage

Creating an Institutional Repository: LEADIRS Workbook

The Learning About Digital Institutional Repositories Seminars programme (LEADIRS) aims to describe and illustrate how to build an online institutional repository. The LEADIRS series of seminars present specialists from the UK and abroad sharing their expertise and experiences in building institutional repositories. This workbook book supplements the seminar presentations and offers practical advice as well as work sheets yo u can use to get started with your own repository programme. Where possible, we point you to real-world examples of planning aids or presentations used by university library teams in the UK and around the world

A brief overview of international trends in Open Access

Definition and stakeholders Open Access can be defined as access to research-based publications that are peer reviewed, permanently and promptly accessible without payment, and re-usable on the sole condition of crediting the author(s). Achieving Open Access (OA) involves all the stakeholders of the research life cycle to begin with the authors who are the initial copyright holders of the publications and then the publishers who coordinate the peer review. Libraries build and maintain the national and institutional infrastructures that facilitate prompt and permanent access. Research funders define conditions for granting financing; mandating access to the resulting publications may be among these conditions. Service providers encourage the reuse of scientific and scholarly findings. Ultimately, legislators may set rules for access to knowledge in our knowledge-permeated democracies

Atrial fibrillation after gastrointestinal surgery: incidence and associated risk factors

BACKGROUND: Atrial fibrillation (AF) is a common dysrhythmia that can occur after major physiological stress including surgery (postoperative AF). There are few data on postoperative AF after abdominal surgery. We set out to define the incidence of de novo postoperative AF after abdominal surgery and associated risk factors. METHODS: The Patient History Integrated Data store administrative database was interrogated for patients aged ≥65 y undergoing abdominal surgery from April 2012 to April 2014. Patients with pre-existing AF were excluded. The primary outcome was diagnosis of AF. RESULTS: Two thousand nine hundred and sixty-seven cases were included of whom 187 developed postoperative AF within 90 d (6.3%). The rate of postoperative AF varied by operation and was highest in small bowel resection (17.2%) and lowest in biliary surgery (4.8%). Median time to detection of postoperative AF was 32 d. Patients who developed postoperative AF were significantly older than those who did not develop AF (median age 75.3 y versus 72.4 y, P < 0.01). Logistic regression modeling found increasing age (odds ratio [OR] 1.03 [confidence interval {CI} 1.01-1.06], hypertension OR 1.73 [CI 1.19-2.51]), congestive cardiac failure (OR 3.04 [CI 1.88-4.92], and vascular disease OR 2.29 [CI 1.39-3.37]) were predictive of the development of postoperative AF within 30 d. The area under the curve for this model was 0.733. CONCLUSIONS: Postoperative AF affects a significant number of patients after abdominal surgery. Demographics such as history of cardiovascular disease might aid prediction of postoperative AF. Postoperative AF is mostly identified after discharge, suggesting the need for postoperative screening

Recombinant plants provide a new approach to the production of bacterial polysaccharide for vaccines

Bacterial polysaccharides have numerous clinical or industrial uses. Recombinant plants could offer the possibility of producing bacterial polysaccharides on a large scale and free of contaminating bacterial toxins and antigens. We investigated the feasibility of this proposal by cloning and expressing the gene for the type 3 synthase (cps3S) of Streptococcus pneumoniae in Nicotinia tabacum, using the pCambia2301 vector and Agrobacterium tumefaciens-mediated gene transfer. In planta the recombinant synthase polymerised plant-derived UDP-glucose and UDP-glucuronic acid to form type 3 polysaccharide. Expression of the cps3S gene was detected by RT-PCR and production of the pneumococcal polysaccharide was detected in tobacco leaf extracts by double immunodiffusion, Western blotting and high-voltage paper electrophoresis. Because it is used a component of anti-pneumococcal vaccines, the immunogenicity of the plant-derived type 3 polysaccharide was tested. Mice immunised with extracts from recombinant plants were protected from challenge with a lethal dose of pneumococci in a model of pneumonia and the immunised mice had significantly elevated levels of serum anti-pneumococcal polysaccharide antibodies. This study provides the proof of the principle that bacterial polysaccharide can be successfully synthesised in plants and that these recombinant polysaccharides could be used as vaccines to protect against life-threatening infections

Development of a Cycling Policy for York Technical Report

In early 1983 York City Council and North Yorkshire County Council commissioned the Institute for Transport Studies to carry out a study of cycling in York. The terms of reference were to: Include an origin and destination survey of current movements by trip purpose and an assessment of future demand, indicating the likely mode from which any transfer will occur; Identify problem areas following discussions with various cycling groups and a study of accident statistics; Take into consideration any previous decisions of the City Council for investigation; Assess the appropriateness of the recommended standards for cycle facilities to a compact urban area; Propose various solutions to problems where appropriate, assess the effect on other road users, and formulate a basic cycling plan for York. Propose various solutions to problems where appropriate, assess the effect on other road users, and formulate a basic cycling plan for York. The Institute for Transport Studies at the Univeristy of Leeds was appointed to carry out the study with Professor A.D. May as the Director of the Study and Mr. D.A. Waring as Research Engineer. Work commenced on this project in June 1983 and was completd in May 1984. The recommendations arising from the study are contained in a separate Summary Report, available from the Institute as Working Paper 175

An evaluation of the lighting environment in the public space of shopping centres

Interior lighting quality influences people's visual comfort and satisfaction with a space. Based on a field study about the effects of lighting environments on occupancies in eight shopping malls with three different latitudes and a wide range of size from 30,000 to 210,000 m2 all over China, this study investigates the differences in subjective evaluations, the correlations between the lighting environments of public spaces and people's evaluations, and the regressions of scene mean luminance. A questionnaire survey and HDR-image techniques have been used to gather subjective feedback and collect physical lighting data. The results show that the subjective evaluations among different groups (gender, age, education background, and duration of stay in the shopping malls) are similar. The existence of daylighting plays an important role in subjective satisfaction, but not crucial enough to their brightness perception. The mean luminance values of these scenes are closely correlated to the diversity of the subjective evaluations. For shopping centres, the optimal Lmean value is 1000 cd/m2 for a mixed daylighting and artificial lighting environment, and 75 cd/m2 as the recommended Lmean value for an artificial lighting environment