Managing stimulation of regional innovation subjects’ interaction in the digital economy

The reported study was funded by RFBR according to the research project No. 18-01000204_a, No. 16-07-00031_a, No. 18-07-00975_a.Purpose: The article is devoted to solving fundamental scientific problems in the scope of the development of forecasting modeling methods and evaluation of regional company’s innovative development parameters, synthesizing new methods of big data processing and intelligent analysis, as well as methods of knowledge eliciting and forecasting the dynamics of regional innovation developments through benchmarking. Design/Methodology/Approach: For regional economic development, it is required to identify the mechanisms that contribute to (or impede) the innovative economic development of the regions. The synergetic approach to management is based on the fact that there are multiple paths of IS development (scenarios with different probabilities), although it is necessary to reach the required attractor by meeting the management goals. Findings: The present research is focused on obtainment of new knowledge in creating a technique of multi-agent search, collection and processing of data on company’s innovative development indicators, models and methods of intelligent analysis of the collected data. Practical Implications: The author developed recommendations before starting the process of institutional changes in a specific regional innovation system. The article formulates recommendations on the implementation of institutional changes in the region taking into account the sociocultural characteristics of the region’s population. Originality/Value: It is the first time, when a complex of models and methods is based on the use of a convergent model of large data volumes processing is presented.peer-reviewe

Personalized medicine—a modern approach for the diagnosis and management of hypertension

The main goal of treating hypertension is to reduce blood pressure to physiological levels and thereby prevent risk of cardiovascular disease and hypertension-associated target organ damage. Despite reductions in major risk factors and the availability of a plethora of effective antihypertensive drugs, the control of blood pressure to target values is still poor due to multiple factors including apparent drug resistance and lack of adherence. An explanation for this problem is related to the current reductionist and ‘trial-and-error’ approach in the management of hypertension, as we may oversimplify the complex nature of the disease and not pay enough attention to the heterogeneity of the pathophysiology and clinical presentation of the disorder. Taking into account specific risk factors, genetic phenotype, pharmacokinetic characteristics, and other particular features unique to each patient, would allow a personalized approach to managing the disease. Personalized medicine therefore represents the tailoring of medical approach and treatment to the individual characteristics of each patient and is expected to become the paradigm of future healthcare. The advancement of systems biology research and the rapid development of high-throughput technologies, as well as the characterization of different –omics, have contributed to a shift in modern biological and medical research from traditional hypothesis-driven designs toward data-driven studies and have facilitated the evolution of personalized or precision medicine for chronic diseases such as hypertension

Storage Solutions for Big Data Systems: A Qualitative Study and Comparison

Big data systems development is full of challenges in view of the variety of application areas and domains that this technology promises to serve. Typically, fundamental design decisions involved in big data systems design include choosing appropriate storage and computing infrastructures. In this age of heterogeneous systems that integrate different technologies for optimized solution to a specific real world problem, big data system are not an exception to any such rule. As far as the storage aspect of any big data system is concerned, the primary facet in this regard is a storage infrastructure and NoSQL seems to be the right technology that fulfills its requirements. However, every big data application has variable data characteristics and thus, the corresponding data fits into a different data model. This paper presents feature and use case analysis and comparison of the four main data models namely document oriented, key value, graph and wide column. Moreover, a feature analysis of 80 NoSQL solutions has been provided, elaborating on the criteria and points that a developer must consider while making a possible choice. Typically, big data storage needs to communicate with the execution engine and other processing and visualization technologies to create a comprehensive solution. This brings forth second facet of big data storage, big data file formats, into picture. The second half of the research paper compares the advantages, shortcomings and possible use cases of available big data file formats for Hadoop, which is the foundation for most big data computing technologies. Decentralized storage and blockchain are seen as the next generation of big data storage and its challenges and future prospects have also been discussed

The Global Warming Potential of Building Materials: An Application of Life Cycle Analysis in Nepal

open6siThis paper analyzes the global-warming potential of materials used to construct the walls of 3 building types—traditional, semimodern, and modern—in Sagarmatha National Park and Buffer Zone in Nepal, using the life-cycle assessment approach. Traditional buildings use local materials, mainly wood and stone, while semimodern and modern buildings use different amounts of commercial materials, such as cement and glass wool. A comparison of the greenhouse gas emissions associated with the 3 building types, using as the functional unit 1 m2 of wall, found that traditional buildings release about one-fourth of the greenhouse gas emissions released by semimodern buildings and less than one-fifth of the emissions of modern buildings. However, the use of thermal insulation in the modern building walls helps to reduce the energy consumption for space heating and consequently to reduce the global warming potential. In 25 years, the total global warming potential of a traditional building will be 20% higher than that of a modern building. If local materials, such as wood, are used in building construction, the emissions from production and transportation could be dramatically reduced.openBhochhibhoya, Silu; Zanetti, Michela; Pierobon, Francesca; Gatto, Paola; Maskey, R. K.; Cavalli, RaffaeleBhochhibhoya, Silu; Zanetti, Michela; Pierobon, Francesca; Gatto, Paola; Maskey, R. K.; Cavalli, Raffael

MobileTrust: Secure Knowledge Integration in VANETs

Vehicular Ad hoc NETworks (VANET) are becoming popular due to the emergence of the Internet of Things and ambient intelligence applications. In such networks, secure resource sharing functionality is accomplished by incorporating trust schemes. Current solutions adopt peer-to-peer technologies that can cover the large operational area. However, these systems fail to capture some inherent properties of VANETs, such as fast and ephemeral interaction, making robust trust evaluation of crowdsourcing challenging. In this article, we propose MobileTrust—a hybrid trust-based system for secure resource sharing in VANETs. The proposal is a breakthrough in centralized trust computing that utilizes cloud and upcoming 5G technologies to provide robust trust establishment with global scalability. The ad hoc communication is energy-efficient and protects the system against threats that are not countered by the current settings. To evaluate its performance and effectiveness, MobileTrust is modelled in the SUMO simulator and tested on the traffic features of the small-size German city of Eichstatt. Similar schemes are implemented in the same platform to provide a fair comparison. Moreover, MobileTrust is deployed on a typical embedded system platform and applied on a real smart car installation for monitoring traffic and road-state parameters of an urban application. The proposed system is developed under the EU-founded THREAT-ARREST project, to provide security, privacy, and trust in an intelligent and energy-aware transportation scenario, bringing closer the vision of sustainable circular economy

Centralized versus market-based approaches to mobile task allocation problem: State-of-the-art

Centralized approach has been adopted for finding solutions to resource allocation problems (RAPs) in many real-life applications. On the other hand, market-based approach has been proposed as an alternative to solve the problem due to recent advancement in ICT technologies. In spite of the existence of some efforts to review the pros and cons of each approach in RAPs, the studies cannot be directly applied to specific problem domains like mobile task allocation problem which is characterised with high level of uncertainty on the availability of resources (workers). This paper aims to review existing studies on task allocation problems(TAPs) focusing on those two approaches and their comparison and identify major issues that need to be resolved for comparing the two approaches in mobile task allocation problems. Mobile Task Allocation Problem (MTAP) is defined and its problematic structures are explained in relation with task allocation to mobile workers. Solutions produced by each approach to some applications and variations of MTAP are also discussed and compared. Finally, some future research directions are identified in order to compare both approaches in function of uncertainty emerging from the mobile nature of the MTAP

e-Science Infrastructure for the Social Sciences

When the term „e-Science“ became popular, it frequently was referred to as “enhanced science” or “electronic science”. More telling is the definition ‘e-Science is about global collaboration in key areas of science and the next generation of infrastructure that will enable it’ (Taylor, 2001). The question arises to what extent can the social sciences profit from recent developments in e- Science infrastructure? While computing, storage and network capacities so far were sufficient to accommodate and access social science data bases, new capacities and technologies support new types of research, e.g. linking and analysing transactional or audio-visual data. Increasingly collaborative working by researchers in distributed networks is efficiently supported and new resources are available for e-learning. Whether these new developments become transformative or just helpful will very much depend on whether their full potential is recognized and creatively integrated into new research designs by theoretically innovative scientists. Progress in e-Science was very much linked to the vision of the Grid as “a software infrastructure that enables flexible, secure, coordinated resource sharing among dynamic collections of individuals, institutions and resources’ and virtually unlimited computing capacities (Foster et al. 2000). In the Social Sciences there has been considerable progress in using modern IT- technologies for multilingual access to virtual distributed research databases across Europe and beyond (e.g. NESSTAR, CESSDA – Portal), data portals for access to statistical offices and for linking access to data, literature, project, expert and other data bases (e.g. Digital Libraries, VASCODA/SOWIPORT). Whether future developments will need GRID enabling of social science databases or can be further developed using WEB 2.0 support is currently an open question. The challenges here are seamless integration and interoperability of data bases, a requirement that is also stipulated by internationalisation and trans-disciplinary research. This goes along with the need for standards and harmonisation of data and metadata. Progress powered by e- infrastructure is, among others, dependent on regulatory frameworks and human capital well trained in both, data science and research methods. It is also dependent on sufficient critical mass of the institutional infrastructure to efficiently support a dynamic research community that wants to “take the lead without catching up”.

Science and Technology Governance and Ethics - A Global Perspective from Europe, India and China

This book analyzes the possibilities for effective global governance of science in Europe, India and China. Authors from the three regions join forces to explore how ethical concerns over new technologies can be incorporated into global science and technology policies. The first chapter introduces the topic, offering a global perspective on embedding ethics in science and technology policy. Chapter Two compares the institutionalization of ethical debates in science, technology and innovation policy in three important regions: Europe, India and China. The third chapter explores public perceptions of science and technology in these same three regions. Chapter Four discusses public engagement in the governance of science and technology, and Chapter Five reviews science and technology governance and European values. The sixth chapter describes and analyzes values demonstrated in the constitution of the People’s Republic of China. Chapter Seven describes emerging evidence from India on the uses of science and technology for socio-economic development, and the quest for inclusive growth. In Chapter Eight, the authors propose a comparative framework for studying global ethics in science and technology. The following three chapters offer case studies and analysis of three emerging industries in India, China and Europe: new food technologies, nanotechnology and synthetic biology. Chapter 12 gathers all these threads for a comprehensive discussion on incorporating ethics into science and technology policy. The analysis is undertaken against the backdrop of different value systems and varying levels of public perception of risks and benefits. The book introduces a common analytical framework for the comparative discussion of ethics at the international level. The authors offer policy recommendations for effective collaboration among the three regions, to promote responsible governance in science and technology and a common analytical perspective in ethics