13 research outputs found

    Automated conflict resolution between multiple clinical pathways:A technology report

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    Background The number of people in the UK with three or more long-term conditions continues to grow and the management of patients with co-morbidities is complex. In treating patients with multimorbidities, a fundamental problem is understanding and detecting points of conflict between different guidelines which to date has relied on individual clinicians collating disparate information. Objective We will develop a framework for modelling a diverse set of care pathways, and investigate how conflicts can be detected and resolved automatically. We will use this knowledge to develop a software tool for use by clinicians that can map guidelines, highlight root causes of conflict between these guidelines and suggest ways they might be resolved. Method Our work consists of three phases. First, we will accurately model clinical pathways for six of the most common chronic diseases; second, we will automatically identify and detect sources of conflict across the pathways and how they might be resolved. Third, we will present a case study to prove the validity of our approach using a team of clinicians to detect and resolve the conflicts in the treatment of a fictional patient with multiple common morbidities and compare their findings and recommendations with those derived automatically using our novel software. Discussion This paper describes the development of an important software-based method for identifying a conflict between clinical guidelines. Our findings will support clinicians treating patients with multimorbidity in both primary and secondary care settings

    Prozessarchitekturen: Anforderungen, Konzepte, Fallbeispiele

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    In der globalisierten und sich stĂ€ndig verĂ€ndernden GeschĂ€ftswelt von heute mĂŒssen sich Unternehmen kontinuierlich verbessern, um am Markt wettbewerbsfĂ€hig zu bleiben. In diesem Kontext ist die Überwachung bzw. Auswertung verschiedenster Kennzahlen von großer Bedeutung, um die Unternehmensleistung bewerten zu können. Jedoch zeigen solche Zahlen nicht, welche GrĂŒnde die aktuelle GeschĂ€ftsperformance hat, wo nachgebessert werden muss oder welche Personen die Verantwortung tragen. Nicht zuletzt durch die EinfĂŒhrung innovativer Technologien stellt das GeschĂ€ftsprozessma-nagement ein unverzichtbares Instrument zu einer Optimierung und Steuerung der UnternehmensablĂ€ufe dar. FĂŒr eine aussagekrĂ€ftige Analyse seiner GeschĂ€ftsprozesse sollte ein Unternehmen seine Prozesslandschaft strukturieren und modellieren. Eine solche Prozessstruktur wird Prozessarchitektur genannt. Da es aufgrund der hohen KomplexitĂ€t nicht angemessen ist, immer alle Prozesse in allen Details darzustellen, gibt es innerhalb einer Prozessarchitektur verschiedene Detailebenen, etwa auf obers-ter Ebene die Prozesslandkarte, welche nur die wichtigsten GeschĂ€ftsprozesse einer Organisation visualisiert. Die vorliegende Arbeit gibt einen Überblick ĂŒber Anforderungen an Prozessarchitekturen sowie den aktuellen Stand der entsprechenden Literatur. Zudem wird durch die Analyse von Fallbeispielen und die Erstellung einer Architektur fĂŒr eine Frauenklinik ein Praxisbe-zug hergestellt. Dazu wird zunĂ€chst eine Literaturrecherche zur Ermittlung des aktuellen Stands der Forschung durchgefĂŒhrt. Hierbei wird eine Einordnung von Prozessarchitek-turen in die Thematik des GeschĂ€ftsprozessmanagements vorgenommen. Es folgt die Vorstellung der wichtigsten Notationen und deren Besonderheiten. Kern der Literaturre-cherche stellen die Anforderungen an eine ordnungsgemĂ€ĂŸe Prozessarchitektur sowie die Ermittlung der Konzepte zur Erstellung von Prozessarchitekturen dar. Auf Basis der gewonnenen Erkenntnisse werden drei Beispielarchitekturen analysiert. Abschließend werden die Ergebnisse dieser Arbeit durch die Erstellung einer Prozessarchitektur fĂŒr eine Frauenklinik veranschaulicht

    Religiöse Individualisierung in historischer Perspektive / Religious Individualisation in Historical Perspective: Abschlussbericht fĂŒr die zweite Förderphase der Kolleg-Forschungsgruppe 1013 / Final Report of the Kolleg-Forschungsgruppe 1013 for the Second Funding Period (2013-2018)

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    This volume provides access to the working and results of six years of research on religious individualisation. It demonstrates the independence of individualisation and modernisation. It has proved that religion is a motor of individualisation. And it has proved that the wide range of phenomena under the umbrella term of 'individualisation' are to be found in many premodern societies, in India for instance as much as in Europe

    Religiöse Individualisierung in historischer Perspektive

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    This volume provides access to the working and results of six years of research on religious individualisation. It demonstrates the independence of individualisation and modernisation. It has proved that religion is a motor of individualisation. And it has proved that the wide range of phenomena under the umbrella term of ‘individualisation’ are to be found in many premodern societies, in India for instance as much as in Europe

    On Pattern Mining in Graph Data to Support Decision-Making

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    In recent years graph data models became increasingly important in both research and industry. Their core is a generic data structure of things (vertices) and connections among those things (edges). Rich graph models such as the property graph model promise an extraordinary analytical power because relationships can be evaluated without knowledge about a domain-specific database schema. This dissertation studies the usage of graph models for data integration and data mining of business data. Although a typical company's business data implicitly describes a graph it is usually stored in multiple relational databases. Therefore, we propose the first semi-automated approach to transform data from multiple relational databases into a single graph whose vertices represent domain objects and whose edges represent their mutual relationships. This transformation is the base of our conceptual framework BIIIG (Business Intelligence with Integrated Instance Graphs). We further proposed a graph-based approach to data integration. The process is executed after the transformation. In established data mining approaches interrelated input data is mostly represented by tuples of measure values and dimension values. In the context of graphs these values must be attached to the graph structure and aggregated measure values are graph attributes. Since the latter was not supported by any existing model, we proposed the use of collections of property graphs. They act as data structure of the novel Extended Property Graph Model (EPGM). The model supports vertices and edges that may appear in different graphs as well as graph properties. Further on, we proposed some operators that benefit from this data structure, for example, graph-based aggregation of measure values. A primitive operation of graph pattern mining is frequent subgraph mining (FSM). However, existing algorithms provided no support for directed multigraphs. We extended the popular gSpan algorithm to overcome this limitation. Some patterns might not be frequent while their generalizations are. Generalized graph patterns can be mined by attaching vertices to taxonomies. We proposed a novel approach to Generalized Multidimensional Frequent Subgraph Mining (GM-FSM), in particular the first solution to generalized FSM that supports not only directed multigraphs but also multiple dimensional taxonomies. In scenarios that compare patterns of different categories, e.g., fraud or not, FSM is not sufficient since pattern frequencies may differ by category. Further on, determining all pattern frequencies without frequency pruning is not an option due to the computational complexity of FSM. Thus, we developed an FSM extension to extract patterns that are characteristic for a specific category according to a user-defined interestingness function called Characteristic Subgraph Mining (CSM). Parts of this work were done in the context of GRADOOP, a framework for distributed graph analytics. To make the primitive operation of frequent subgraph mining available to this framework, we developed Distributed In-Memory gSpan (DIMSpan), a frequent subgraph miner that is tailored to the characteristics of shared-nothing clusters and distributed dataflow systems. Finally, the results of use case evaluations in cooperation with a large scale enterprise will be presented. This includes a report of practical experiences gained in implementation and application of the proposed algorithms

    Bronzezeitlicher Transport. Akteure, Mittel und Wege

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    WeitrĂ€umige Kontaktnetzwerke sorgen fĂŒr Verbreitung und Transfer von Wissen und GĂŒtern sowie von kulturellen Werten. Der Transport von Lasten und Menschen kann als einer der wichtigsten Eckpfeiler solcher Austauschsysteme gesehen werden. Daher dĂŒrften die Suche nach Transportmöglichkeiten und die Entwicklung geeigneter Vehikel in der menschlichen Gedankenwelt seit jeher fest verankert sein. Die hier vorliegenden BeitrĂ€ge basieren auf den VortrĂ€gen der Tagung „Transporte, Transportwege und Transportstrukturen“ der Arbeitsgemeinschaft Bronzezeit und des Sonderforschungsbereiches 1070 RessourcenKulturen. Sie fassen im archĂ€ologischen Befund der Bronzezeit vorhandene Evidenzen zu Transportwegen und -fahrzeugen sowie Aussagen zu Infrastruktur nicht nur zusammen, sondern ergĂ€nzen diese um zahlreiche wissenswerte Aspekte. Was können diese Befunde ĂŒber die Transportvehikel und ihre Bedeutung aussagen? Welche Eigenschaften wiesen diese auf? Handelt es sich bei den FundstĂŒcken um abgenutzte oder mutwillig zerstörte Fahrzeuge bzw. Teile von solchen? Welche Implikationen auf technologischer und sozialer Ebene lassen sich mit den Befunden verbinden? Wie muss man sich die bronzezeitliche Infrastruktur in unterschiedlichen Regionen vorstellen? Inwiefern bildeten Verkehrswege und Austausch eine Ressource? Der detaillierten Beantwortung dieser Fragen ist dieser Band gewidmet, woraus eine ĂŒbergreifende Zusammenschau von Funden, Befunden und Theorien entstanden ist

    Hellenostephanos. Humanist Greek in Early Modern Europe

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    The rebirth of Ancient Greek in Europe was promoted by Humanist education and ideas to such an extent that we can consider the Greek language as a formative element of Humanist culture. Next to Latin, the default common language, a Humanist has to know and use Greek, because he is not, cannot and will not be a barbarian: barbaros ou pelomai, as Julius Caesar Scaliger claimed in his verses in 1600. Wreaths (stephanoi) have been the symbols of the cult of Muses from ancient times. After the love for Greek Muses had been revived by Renaissance Humanist poets and scholars, it has remained with us both in poetic activity and in scholarship. The Hellenostephanos volume presents a collection of papers by scholars who study Humanist Greek, aspiring towards another revival of Hellenism, and trying to avoid being barbarians. The volume includes papers by Christian Gastgeber, Gita BērziƆa, Janika PĂ€ll, Charalampos Minaoglou, Erkki Sironen, Kaspar Kolk, Tua Korhonen, Johanna AkujĂ€rvi, Bartosz Awianowicz, Jean-Marie Flamand, Walther Ludwig, Alessandra Lukinovich, Martin SteinrĂŒck, Tomas Veteikis, Grigory Vorobyev, Vlado Rezar, Pieta van Beek, and Antoine Haaker

    „Trinkt von dem Wein, den ich mischte!“ “Drink of the wine which I have mingled!” Festschrift fĂŒr Silvia Schroer zum 65. Geburtstag

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    Die in diesem Band versammelten BeitrĂ€ge wĂŒrdigen das vielfĂ€ltige Wirken von Silvia Schroer in biblischer Exegese, Ikonographie, feministischer Kritik und der breiten Erforschung von Texten und Bildern des Alten Israel und seiner Nachbarkulturen. WeggefĂ€hrt*innen, die verschiedenen Generationen von Forschenden angehören, schlagen in 35 AufsĂ€tzen BrĂŒcken zwischen ihrer eigenen Forschung und Silvias Werk, indem sie in einer bunten Festschrift dessen Höhepunkte und vielfĂ€ltige Anschlussmöglichkeiten markieren. The contributions gathered in this volume honor the work of Silvia Schroer in biblical exegesis, iconography, feminist criticism, and the broad exploration of texts and images from Ancient Israel and neighboring cultures. Across 35 contributions, companions representing different generations of researchers relate their own work to Silvia’s scholarship, pointing to some of the latter’s highlights and connectivity in a colorful Festschrift
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