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Improving the energy efficiency of room air conditioners in China: Costs and benefits
China is the world's largest consumer of room air conditioners, and it contributes about a quarter of global space cooling CO2 emissions. We model the costs and benefits of recently proposed new room air conditioner minimum energy performance standards (MEPS) in China. Our results suggest that newly proposed MEPS brings accumulative CO2 emissions reductions of 12.8% between 2019 and 2050, and accumulative bill saving of 2620 billion RMB to China's consumers. The benefits of the proposed MEPS decrease with longer MEPS revision intervals and increase with shorter intervals—indicating that the intervals should be balanced to maximize benefits while accommodating constraints due to air conditioner manufacturer design cycles. We also model potential nationwide benefits from higher MEPS. Across two increasingly aggressive MEPS scenarios, China's room air conditioner electricity consumption and CO2 emissions in 2050 are both reduced by 15–53% compared to the proposed MEPS. The highest-efficiency scenario (reaching MEPS of annual performance factor 5.4 in 2025) provides the largest long-term national benefits. These results could inform development of a Chinese regulatory regime that effectively updates room air conditioner MEPS. Because China is the world's largest manufacturer of room air conditioners, the economic, energy, and emissions benefits resulting from higher Chinese MEPS could also have a global reach
Induction of chronic migraine phenotypes in a rat model after environmental irritant exposure
Air pollution is linked to increased emergency department visits for headache and migraine patients frequently cite chemicals or odors as headache triggers, but the association between air pollutants and headache is not well understood. We previously reported that chronic environmental irritant exposure sensitizes the trigeminovascular system response to nasal administration of environmental irritants. Here, we examine whether chronic environmental irritant exposure induces migraine behavioral phenotypes. Male rats were exposed to acrolein, a transient receptor potential channel ankyrin-1 (TRPA1) agonist, or room air by inhalation for 4 days before meningeal blood flow measurements, periorbital cutaneous sensory testing, or other behavioral testing. Touch-induced c-Fos expression in trigeminal nucleus caudalis was compared in animals exposed to room air or acrolein. Spontaneous behavior and olfactory discrimination was examined in open-field testing. Acrolein inhalation exposure produced long-lasting potentiation of blood flow responses to a subsequent TRPA1 agonist and sensitized cutaneous responses to mechanical stimulation. C-Fos expression in response to touch was increased in trigeminal nucleus caudalis in animals exposed to acrolein compared with room air. Spontaneous activity in an open-field and scent preference behavior was different in acrolein-exposed compared with room air-exposed animals. Sumatriptan, an acute migraine treatment blocked acute blood flow changes in response to TRPA1 or transient receptor potential vanilloid receptor-1 agonists. Pretreatment with valproic acid, a prophylactic migraine treatment, attenuated the enhanced blood flow responses observed after acrolein inhalation exposures. Environmental irritant exposure yields an animal model of chronic migraine in which to study mechanisms for enhanced headache susceptibility after chemical exposure
Dispersion of microbes from floors when walking in ventilated rooms
The redispersion factor of microbe-carrying particles, which is the ratio of the concentration of floor-derived microbes in room air to those on a floor surface, was determined, as was the percentage of floor-derived microbes in room air. These relationships were shown to vary according to conditions in the room. Equations were derived that allow these relationships to be calculated for a variety of room conditions, including air supply rates, levels of personnel activity, and the effect of gravitational deposition on microbe-carrying particles.<p></p>
The redispersion factor in ventilated rooms, such as cleanrooms and operating rooms, when the floor surface concentration was measured by nutrient agar contact dishes, was found to vary from about 1.5 x 10-4 to 7.4 x 10-6, and the percentage of floor-derived microbes in room air from about 0.004% to 10.5%. In a typical cleanroom, the redispersion factor is likely to be about 1.0 x 10-4, and the percentage of floor-derived microbes, 0.7. In a typical operating room, the redispersion factor is likely to be about 5.2 x 10-6 and the percentage of floor-derived microbes, 2.<p></p>
Energy Consumption Estimation for Room Air-conditioners Using Room Temperature Simulation with One-Minute Intervals
For the purpose of developing optimized control algorithm for room air-conditioners to ensure their energy efficiency, a short time interval (i.e., one minute) simulation of building thermal performance is necessary because the sampling time interval for room air-conditioner control is one minute in general. This paper studies the short-time interval room air temperature simulation method using the response factor method. Using the simulated room air temperature, an air-conditioner's running time can be known so that its energy consumption can be estimated accurately. In order to verify the simulation accuracy, an actual room equipped with a gas-engine heat pump (GHP) air-conditioning system is studied by both simulation and measurement. The cooling amount produced by the GHP is calculated using measured refrigerant pressure and temperature at condenser and evaporator respectively. The Root Mean Square Error (RMSE) between measured cooling amount and simulated cooling load is 18.9 percent of the average measured value. The profile of simulated room air temperature in both air-conditioned daytime and nighttime without air-conditioning can match the measured room air temperature. With respect to the estimated energy consumption, the profile of simulated energy consumption can match the measured data. The simulation accuracy of room air temperature and energy consumption during the air-conditioner start-up period is not good and needs to be improved in future research. But in general, the verification shows that this energy consumption simulation method is acceptable for evaluating the energy performance of a room air-conditioner, and can also be a useful tool for commissioning room air-conditioners
Nasal high flow in room air for hypoxemic bronchiolitis infants
Background: Bronchiolitis is the most common reason for hospital admission in infants, with one third requiring oxygen therapy due to hypoxemia. It is unknown what proportion of hypoxemic infants with bronchiolitis can be managed with nasal high-flow in room air and their resulting outcomes.
Objectives and Settings: To assess the effect of nasal high-flow in room air in a subgroup of infants with bronchiolitis allocated to high-flow therapy in a recent multicenter randomized controlled trial.
Patients and Interventions: Infants allocated to the high-flow arm of the trial were initially treated with room air high-flow if saturations were ≥85%. Subsequently, if oxygen saturations did not increase to ≥92%, oxygen was added and FiO2 was titrated to increase the oxygen saturations. In this planned sub-study, infants treated during their entire hospital stay with high-flow room air only were compared to infants receiving either standard-oxygen or high-flow with oxygen. Baseline characteristics, hospital length of stay and length of oxygen therapy were compared.
Findings: In the per protocol analysis 64 (10%) of 630 infants commenced on high-flow room air remained in room air only during the entire stay in hospital. These infants on high-flow room air were on average older and presented with moderate hypoxemia at presentation to hospital. Their length of respiratory support and length of stay was also significantly shorter. No pre-enrolment factors could be identified in a multivariable analysis.
Conclusions: In a small sub-group of hypoxemic infants with bronchiolitis hypoxemia can be reversed with the application of high-flow in room air only
Effect of barrier height on friction behavior of the semiconductors silicon and gallium arsenide in contact with pure metals
Friction experiments were conducted for the semiconductors silicon and gallium arsenide in contact with pure metals. Polycrystalline titanium, tantalum, nickel, palladium, and platinum were made to contact a single crystal silicon (111) surface. Indium, nickel, copper, and silver were made to contact a single crystal gallium arsenide (100) surface. Sliding was conducted both in room air and in a vacuum of 10 to the minus 9th power torr. The friction of semiconductors in contact with metals depended on a Schottky barrier height formed at the metal semiconductor interface. Metals with a higher barrier height on semiconductors gave lower friction. The effect of the barrier height on friction behavior for argon sputtered cleaned surfaces in vacuum was more specific than that for the surfaces containing films in room air. With a silicon surface sliding on titanium, many silicon particles back transferred. In contrast, a large quantity of indium transferred to the gallium arsenide surface
Alveolar Recruitment Maneuvers and Noninvasive Positive Pressure Ventilation in Obese Patients: A Quality Improvement Project
Obesity is considered a complex, and often difficult to manage the diseasethat develops due to many factors. Over one-third of the U.S. population is considered to be obese with Mississippi ranked as second highest in adult obesity (WHO, 2016). With the increasedprevalence of obese patients, it is inevitable that these patients will be presenting for surgical procedures. Obesity and its comorbidities can prove to be challenging for anesthesia providers. These patients often will have compromised respiratory function due to an accumulation of adipose tissue on the abdominal, thoracic, and diaphragmatic structures(Nagelhout, 2014). General anesthesia causes atelectasis and reductions in lung volume in the obese surgical patient(Futier et al., 2011). To combat the physiological challenges this patient population presents with, anesthesia providers must stay up to date with current evidence-based practice to prevent negative outcomes. Current evidence-based practice and literature supportthe utilization of noninvasive positive pressure ventilation (NIPPV), alveolar recruitment maneuvers (ARM), and positive end-expiratorypressure (PEEP) to improve obese surgical patient outcomes (Forgiarini, Rezende, & Forgiarini, 2013).
A quality improvement project was implemented which included the comparison between using NIPPV, ARM, and PEEP on induction of general anesthesia and traditional pre-oxygenation techniques. Over the course of a four-week time period, 14 participants meeting the inclusion criteria were included in this intervention. Seven participants, group one received the intervention and seven, group two did not. Group one showed an improvement in postoperative room air saturation over the preoperative room air saturation. Group twoshowed no improvement in postoperative room air saturation versus the recorded preoperative room air saturation. The usage of NIPPV, ARM, and PEEP resulted in improved post-operative room air saturated oxygen level (SpO2) on arrival to the post-anesthesia care unit as compared to the preoperative room air saturation
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