Biological variables in forager fertility performance: a critique of Bongaarts' model

African Studies Center Working Paper No. 60During the period of the 1960s and 1970s, a considerable amount of scholarly energy was devoted to studying the process of "modernization." Scholars, particularly political scientists and anthropologists, theorized extensively over exactly what modernization was and debated how it could best be quantified and measured.1 By the 1980s, however, the very notion of the "modern," along with its antithesis, the "traditional" was falling out of favor. Indeed, by declaring the new era "post-modern," the academic avant-guard signaled that the concept of modernity had effectively been relegated to the past. The past, however, is the turf of historians, so perhaps now that the concept of modernity has become old-fashioned it is time for historians to take their turn at examining its meaning. This paper will approach the concept of the "modern" by examining the role of advertising in creating notions of modernity in independence-era Ghana. Ghana, at the time of independence in 1957, was a country of supreme optimism about the future. Not only did Ghanaians see themselves as being on the cutting edge politically (as the first sub-Saharan colony to achieve independence), but they also believed that independence would bring a new era of economic development and wealth. Ghana, as a country, was "going places." The new nation's optimism found many manifestations, but this paper will focus on only one aspect of this exuberance—representations of transportation as modernity in the advertisements and articles of Ghana's premier newspaper, the Daily Graphic. As stated before, early scholarship on modernization was concerned primarily with developing a way of measuring the demise of the traditional and the rise of the modern. Such studies focused on examining populations of "traditional" or "transitional" peoples to attempt to discern just how "modern" they had or had not become. What the previous studies did not consider, and what this paper seeks to examine, is exactly how modernity was presented to and by such populations. No single factor seems to represent modernity more than motion itself—be it actual movement across space or be it social and economic change. Indeed, Daniel Lerner, the prominent scholar of modernity, defined the key aspect of being modern as having... [TRUNCATED

Biological variables in social surveys

"Social scientists have long virtually ignored the biological constraints of human behavior. Yet if the prediction of behavior is considered essential to a social science, neglecting any variable that might influence human behavior is unacceptable. This paper provides examples of important biological variables and describes their measurement in social surveys." (author's abstract

Biological Variables in Social Surveys

Social scientists have long virtually ignored the biological constraints of human behavior. Yet if the prediction of behavior is considered essential to a social science, neglecting any variable that might influence human behavior is unacceptable. This paper provides examples of important biological variables and describes their measurement in social surveys.

The motivating operation and negatively reinforced problem behavior. A systematic review.

The concept of motivational operations exerts an increasing influence on the understanding and assessment of problem behavior in people with intellectual and developmental disability. In this systematic review of 59 methodologically robust studies of the influence of motivational operations in negative reinforcement paradigms in this population, we identify themes related to situational and biological variables that have implications for assessment, intervention, and further research. There is now good evidence that motivational operations of differing origins influence negatively reinforced problem behavior, and that these might be subject to manipulation to facilitate favorable outcomes. There is also good evidence that some biological variables warrant consideration in assessment procedures as they predispose the person's behavior to be influenced by specific motivational operations. The implications for assessment and intervention are made explicit with reference to variables that are open to manipulation or that require further research and conceptualization within causal models

MEDICINE IN CRISIS OR IN FRONT OF NEW OPPORTUNITIES

The author presents classification of medical sciences from a holistic perspective. Modern classification based on structural functionalism shows a lack of consistency. Holistic vision, based on role determinism, considers function as a role of the organ in biological variables determination. Biological variables plays an organizing role in the overall functioning of the body and determines its physiological identity being healthy or sick. Holistic vision could be successfully applied in medical theory, diagnosis and education

Correlation analysis of two-dimensional gel electrophoretic protein patterns and biological variables

BACKGROUND: Two-dimensional gel electrophoresis (2DE) is a powerful technique to examine post-translational modifications of complexly modulated proteins. Currently, spot detection is a necessary step to assess relations between spots and biological variables. This often proves time consuming and difficult when working with non-perfect gels. We developed an analysis technique to measure correlation between 2DE images and biological variables on a pixel by pixel basis. After image alignment and normalization, the biological parameters and pixel values are replaced by their specific rank. These rank adjusted images and parameters are then put into a standard linear Pearson correlation and further tested for significance and variance. RESULTS: We validated this technique on a set of simulated 2DE images, which revealed also correct working under the presence of normalization factors. This was followed by an analysis of p53 2DE immunoblots from cancer cells, known to have unique signaling networks. Since p53 is altered through these signaling networks, we expected to find correlations between the cancer type (acute lymphoblastic leukemia and acute myeloid leukemia) and the p53 profiles. A second correlation analysis revealed a more complex relation between the differentiation stage in acute myeloid leukemia and p53 protein isoforms. CONCLUSION: The presented analysis method measures relations between 2DE images and external variables without requiring spot detection, thereby enabling the exploration of biosignatures of complex signaling networks in biological systems

Engineering analysis of biological variables: An example of blood pressure over 1 day

Almost all variables in biology are nonstationarily stochastic. For these variables, the conventional tools leave us a feeling that some valuable information is thrown away and that a complex phenomenon is presented imprecisely. Here, we apply recent advances initially made in the study of ocean waves to study the blood pressure waves in the lung. We note first that, in a long wave train, the handling of the local mean is of predominant importance. It is shown that a signal can be described by a sum of a series of intrinsic mode functions, each of which has zero local mean at all times. The process of deriving this series is called the “empirical mode decomposition method.” Conventionally, Fourier analysis represents the data by sine and cosine functions, but no instantaneous frequency can be defined. In the new way, the data are represented by intrinsic mode functions, to which Hilbert transform can be used. Titchmarsh [Titchmarsh, E. C. (1948) Introduction to the Theory of Fourier Integrals (Oxford Univ. Press, Oxford)] has shown that a signal and i times its Hilbert transform together define a complex variable. From that complex variable, the instantaneous frequency, instantaneous amplitude, Hilbert spectrum, and marginal Hilbert spectrum have been defined. In addition, the Gumbel extreme-value statistics are applied. We present all of these features of the blood pressure records here for the reader to see how they look. In the future, we have to learn how these features change with disease or interventions

A False Start in the Race Against Doping in Sport: Concerns With Cycling’s Biological Passport

Professional cycling has suffered from a number of doping scandals. The sport’s governing bodies have responded by implementing an aggressive new antidoping program known as the biological passport. Cycling’s biological passport marks a departure from traditional antidoping efforts, which have focused on directly detecting prohibited substances in a cyclist’s system. Instead, the biological passport tracks biological variables in a cyclist’s blood and urine over time, monitoring for fluctuations that are thought to indirectly reveal the effects of doping. Although this method of indirect detection is promising, it also raises serious legal and scientific concerns. Since its introduction, the cycling community has debated the reliability of indirect biological-passport evidence and the clarity, consistency, and transparency of its use in proving doping violations. Such uncertainty undermines the legitimacy of finding cyclists guilty of doping based on this indirect evidence alone. Antidoping authorities should address these important concerns before continuing to pursue doping sanctions against cyclists solely on the basis of their biological passports