301 research outputs found
Горшкоподібний посуд: етнокультурні взаємовпливи
The article brings complex comparative analitical study in Ukrainian and foreign types of pottery kitchenware with throwing light upon common and different features in forms and decorations of artefacts as well as with definitions of most characteristic notions that underline originality and nature of Ukrainian ceramics in the context of All-European culture
Социально-экономическое развитие Кировского района
В статье раскрывается социально-экономическое развитие Кировского района, сравниваются показатели района с показателями по Автономной Республике Крым в целом. Раскрывается туристско-ресурсный потенциал города Старый Крым и делается предположение, как эффективно использовать имеющийся потенциал для развития Кировского района в целом.В статті розкривається соціально-економічний розвиток Кіровського району, порівнюються показники району з показниками по Автономній Республіці Крим в цілому. Розкривається туристсько-ресурсний потенціал міста Старий Крим і робиться припущення, як ефективно використовувати наявний потенціал для розвитку Кіровського району в цілому.In the article is described the social and the economic development of the Kirovsk district of the Autonomous Republic of Crimea, and are compared the parameters of the district with the parametrs in Autonomous Republic of Crimea in the whole. In this article are shown tourist's and spa resorts of the town Stary Krym and is made the proposal how to use the potential of the town for the development of the Kirovsk district in the whole
Role of germline aberrations affecting CTNNA1, MAP3K6 and MYD88 in gastric cancer susceptibility
Background: In approximately 10% of all gastric cancer (GC) cases, a heritable cause is suspected. A subset of these cases have a causative germline CDH1 mutation; however, in most cases the cause remains unknown. Our objective was to assess to what extent these remaining cases may be explained by germline mutations in the novel candidate GC predisposing genes CTNNA1, MAP3K6 or MYD88. Methods: We sequenced a large cohort of unexplained young and/or familial patients with GC (n=286) without a CDH1germline mutation for germline variants affecting CTNNA1, MAP3K6 and MYD88 using a targeted next-generation sequencing approach based on single-molecule molecular inversion probes. Results: Predicted deleterious germline variants were not encountered in MYD88, but recurrently observed in CTNNA1 (n=2) and MAP3K6 (n=3) in our cohort of patients with GC. In contrast to deleterious variants in CTNNA1, deleterious variants in MAP3K6 also occur frequently in the general population. Conclusions: Based on our results MAP3K6 should no longer be considered a GC predisposition gene, whereas deleterious CTNNA1 variants are confirmed as an infrequent cause of GC susceptibility. Biallelic MYD88 germline mutations are at most a very rare cause of GC susceptibility as no additional cases were identified
Unraveling genetic predisposition to familial or early onset gastric cancer using germline whole-exome sequencing
Recognition of individuals with a genetic predisposition to gastric cancer (GC) enables preventive measures. However, the underlying cause of genetic susceptibility to gastric cancer remains largely unexplained. We performed germline whole-exome sequencing on leukocyte DNA of 54 patients from 53 families with genetically unexplained diffuse-type and intestinal-type GC to identify novel GC-predisposing candidate genes. As young age at diagnosis and familial clustering are hallmarks of genetic tumor susceptibility, we selected patients that were diagnosed below the age of 35, patients from families with two cases of GC at or below age 60 and patients from families with three GC cases at or below age 70. All included individuals were tested negative for germline CDH1 mutations before or during the study. Variants that were possibly deleterious according to in silico predictions were filtered using several independent approaches that were based on gene function and gene mutation burden in controls. Despite a rigorous search, no obvious candidate GC predisposition genes were identified. This negative result stresses the importance of future research studies in large, homogeneous cohorts
Partonic flow and -meson production in Au+Au collisions at = 200 GeV
We present first measurements of the -meson elliptic flow
() and high statistics distributions for different
centralities from = 200 GeV Au+Au collisions at RHIC. In
minimum bias collisions the of the meson is consistent with the
trend observed for mesons. The ratio of the yields of the to those of
the as a function of transverse momentum is consistent with a model
based on the recombination of thermal quarks up to GeV/,
but disagrees at higher momenta. The nuclear modification factor () of
follows the trend observed in the mesons rather than in
baryons, supporting baryon-meson scaling. Since -mesons are
made via coalescence of seemingly thermalized quarks in central Au+Au
collisions, the observations imply hot and dense matter with partonic
collectivity has been formed at RHIC.Comment: 6 pages, 4 figures, submit to PR
Plasma Wakefield Acceleration with a Modulated Proton Bunch
The plasma wakefield amplitudes which could be achieved via the modulation of
a long proton bunch are investigated. We find that in the limit of long bunches
compared to the plasma wavelength, the strength of the accelerating fields is
directly proportional to the number of particles in the drive bunch and
inversely proportional to the square of the transverse bunch size. The scaling
laws were tested and verified in detailed simulations using parameters of
existing proton accelerators, and large electric fields were achieved, reaching
1 GV/m for LHC bunches. Energy gains for test electrons beyond 6 TeV were found
in this case.Comment: 9 pages, 7 figure
The energy dependence of angular correlations inferred from mean- fluctuation scale dependence in heavy ion collisions at the SPS and RHIC
We present the first study of the energy dependence of angular
correlations inferred from event-wise mean transverse momentum
fluctuations in heavy ion collisions. We compare our large-acceptance
measurements at CM energies $\sqrt{s_{NN}} =$ 19.6, 62.4, 130 and 200 GeV to
SPS measurements at 12.3 and 17.3 GeV. $p_t$ angular correlation structure
suggests that the principal source of $p_t$ correlations and fluctuations is
minijets (minimum-bias parton fragments). We observe a dramatic increase in
correlations and fluctuations from SPS to RHIC energies, increasing linearly
with $\ln \sqrt{s_{NN}}$ from the onset of observable jet-related
fluctuations near 10 GeV.Comment: 10 pages, 4 figure
Measurement of Transverse Single-Spin Asymmetries for Di-Jet Production in Proton-Proton Collisions at GeV
We report the first measurement of the opening angle distribution between
pairs of jets produced in high-energy collisions of transversely polarized
protons. The measurement probes (Sivers) correlations between the transverse
spin orientation of a proton and the transverse momentum directions of its
partons. With both beams polarized, the wide pseudorapidity () coverage for jets permits separation of Sivers functions for the valence
and sea regions. The resulting asymmetries are all consistent with zero and
considerably smaller than Sivers effects observed in semi-inclusive deep
inelastic scattering (SIDIS). We discuss theoretical attempts to reconcile the
new results with the sizable transverse spin effects seen in SIDIS and forward
hadron production in pp collisions.Comment: 6 pages total, 1 Latex file, 3 PS files with figure
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