114 research outputs found

    Salt-tolerant plants as sources of Antiparasitic Agents for human use: A comprehensive review

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    Parasitic diseases, especially those caused by protozoans and helminths, such as malaria, trypanosomiasis, leishmaniasis, Chagas disease, schistosomiasis, onchocerciasis, and lymphatic filariasis, are the cause of millions of morbidities and deaths every year, mainly in tropical regions. Nature has always provided valuable antiparasitic agents, and efforts targeting the identification of antiparasitic drugs from plants have mainly focused on glycophytes. However, salt-tolerant plants (halophytes) have lately attracted the interest of the scientific community due to their medicinal assets, which include antiparasitic properties. This review paper gathers the most relevant information on antiparasitic properties of halophyte plants, targeting human uses. It includes an introduction section containing a summary of some of the most pertinent characteristics of halophytes, followed by information regarding the ethnomedicinal uses of several species towards human parasitic diseases. Then, information is provided related to the antiprotozoal and anthelmintic properties of halophytes, determined by in vitro and in vivo methods, and with the bioactive metabolites that may be related to such properties. Finally, a conclusion section is presented, addressing perspectives for the sustainable exploitation of selected species.info:eu-repo/semantics/publishedVersio

    The role of emerging technologies in the dehydration of berries: Quality, bioactive compounds, and shelf life

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    Financiaciado para publicación en acceso aberto: Universidade de Vigo/CISUGBerries are among the fruits with the highest nutritional and commercial value. This paper reviews the conventional and emerging dehydration methods most commonly used as postharvest treatment and discusses their efficacy in maintaining and/or improving the nutritional and functional qualities of dried berries. The characteristics of the conventional methods (e.g., convective drying, freeze-drying, spray-drying, osmotic dehydration), their pre-treatments, their combination, and intermittent drying, as well as their potential disadvantages are discussed. The use of emerging dehydration techniques (e.g., electromagnetic radiation drying, explosion puffing drying, heat pump drying, low-pressure superheated steam drying, microwave drying) allows to improve the quality of the dried berries compared to conventional techniques, in addition to reducing drying times, increasing drying speed and energy efficiency. Finally, the use of pre-treatments and the combination of technologies can enhance the quality of the final product as a result of the improvement in the effectiveness of the dehydration processGAIN (Axencia Galega de Innovación) | Ref. IN607A2019/0

    Phytochemical analysis and biological evaluation of three selected Cordia species from Panama

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    The aim of the present study was the phytochemical analysis of the leaves from three not previously studied tropical species Cordia bicolor, Cordia megalantha and Cordia dentata (Boraginaceae) collected from Panama. The genus Cordia is one of the major and most important of the family and involves a wide range of therapeutic uses in traditional medicine. Eleven known compounds allantoin (1), rosmarinic acid (2), caffeic acid (3), isoquercetin (4), rutin (5), quercetin-3-Ο-β-D-neohesperidoside (6), kaempferol 3-Ο-β-D-neohesperidoside (7), helichrysoside (8), kaempferol 3-O-(2″-O-α-L-rhamnosyl-6″trans-p-coumaroyl)-β-D-glucoside (9), quercetin 3-O-(6″ trans-p-coumaroyl)-β-D-galactoside (10), 4-hydroxyphenyl lactic acid (11), have been isolated and structurally elucidated. Compounds 6 and 7 have been isolated for the first time in Cordia genus, compounds 8-10 are reported for the first time in the Boraginaceae family, while secondary metabolite 9 is isolated as natural product for the second time. The methanolic extracts of the plants have been assayed for their antioxidant properties by free radical scavenging, reducing power, phosphomolybdenum and metal chelating assay. Enzyme inhibitory activity has been also evaluated against cholinesterases, α-amylase and α-glucosidase. C. megalantha exhibited the strongest antioxidant activity compared to the other studied Cordia species and a high inhibitory activity against α-glucosidase, which suggests that this herbal material could be used for further studies as a potential source for therapeutic applications

    Berberine, a popular dietary supplement for human and animal health: Quantitative research literature analysis a review

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    Berberine is an alkaloid with a wide range of reported beneficial health effects. The current work provides an extensive literature analysis on berberine. Bibliometric data were identified by means of the search string TOPIC=(berberin* OR umbellatine*), which yielded 5,547 publications indexed in the Web of Science Core Collection electronic database. The VOSviewer software generated bubble maps to visualize semantic terms with citation results. The ratio of original articles to reviews was 13.6:1. The literature has been growing more quickly since the 2010s. Major contributing countries were China, the United States, India, Japan, and South Korea. Most of the publications appeared in journals specialized in pharmacology pharmacy, biochemistry molecular biology, chemistry, and plant science. Some of the frequently mentioned chemicals/chemical classes were alkaloid, palmatine, jatrorrhizine, coptisine, isoquinoline, and sanguinarine. The prevalent medical conditions under investigation included Alzheimers disease, cancer, diabetes, and obesity.Acknowledge the support by the Polish KNOW (LeadingNational Research Centre) Scientific Consortium “Healthy Animal-Safe Food,” decision of Ministry of Science and Higher Education No. 05-1/KNOW2/2015 and the European Union under the European Regional Development Fund (Homing/2017-4/41). Antoni Sureda has been supported by the Institute of Health Carlos III (Project CIBEROBN CB12/03/30038). Joanna Feder-Kubis was financed by the Polish Ministry of Science and Higher Education for the Faculty of Chemistry of Wrocław University of Science and Technology.info:eu-repo/semantics/publishedVersio

    Derilerde yağ kusmasına neden olan faktörlerin kromatografik yöntemlerle araştırılması

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    Yag kusması; özellikle mamul derilerde görülen ve derilerin deger kaybına neden olan en önemli kusurlardan biridir. Problemin kaynagı olarak dogal hayvansal yagların türü, yaglama maddeleri, yag gidermede kullanılan emülgatörler ve uygun olmayan islem kosulları gösterilmekle beraber, asıl neden hakkında net bir bilimsel açıklama bulunmamaktadır. Arastırmada dogal yag oranı yüksek rlanda koyun derileri kullanılmıstır. Birinci grup derilere yag giderme ve yaglama islemi yapılmamıs, ikinci ve üçüncü grup derilere ise yag giderme yapılmıstır. kinci gruba yaglama islemi yapılmadan, üçüncü grup deriler ise %3,5,7 yag emülsiyonu verilerek islenmistir. Dogal yag örneklerinin yapısal özelliklerini ortaya koymak için; yaglamadan önce ve sonra asit ve iyot sayısı, yogunluk, refraktif indeks ile termal testleri yapılmıstır. Ham derilerden yag giderme isleminden önce ve sonra SEM görüntüleri alınmıs, NMR ve GC analizleri yapılarak kusma olayına neden olan bilesenler arastırılmıstır. Palmitik ve stearik asitlerin ana sorumlu oldugu belirlenmistir

    Klinoptilolit zeolitinin deri sanayiinde kullanılması üzerine bir araştırma

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    Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz.ÖZET KLİNOPTİLOLİT ZEOLİTİNİN DERİ SANAYİİNDE KULLANILMASI ÜZERİNE BİR ARAŞTIRMA ZENGİN, Gökhan Yüksek Lisans Tezi, Deri Teknolojisi Bölümü Tez Yöneticisi : Yrd. Doç. Dr. Bekir YILMAZ Ocak 2001, 172 sayfa Bu çalışmada klinoptilolit olarak bilinen doğal zeolitin deri sanayiinde kullanılabilirliği araştırılmıştır. Öncelikle klinoptilolitin krom tabaklamada deriye kazandırdığı özellikler tesbit edilmeye çalışılmıştır. Ayrıca farklı tabaklama maddeleri ile klinoptilolit arasındaki etkileşimler karşılaştırmalı olarak incelenmiştir. Denemelerde Na-klinoptilolitin deri rengine etkisi araştırılmış, bu amaçla retenaj ve yağlama işleminden sonra derilerde renk ölçümleri yapılmış; kopma, yırtılma ve dikiş yırtılma dayanımları, ile yumuşaklık testleri uygulanmıştır. Ayrıca sülfat külü, % nem, pH, %Cr203, Al, Si, suda çözünen madde, diklormetanda çözünen madde tayini yapılmıştır. Klinoptilolitin farklı tabaklama maddeleri ile kombinasyonlarının değerlendirmesinde ikili varyans analizi, Fishers PLSD testi; krom klinoptilolit kombinasyonlarının değerlendirilmesinde ise Duncan testi, t testi uygulanmıştırvn ABSTRACT STUDY ON THE USAGE OF CLEVOPTTLOLITE TYPE ZEOLITE IN LEATHER INDUSTRY ZENGİN, Gökhan MSc in Leather Technology Supervisor: Yrd. Doç. Dr. Bekir YDLMAZ January 2001, 172 pages In this study, one of the natural zeolite known as clinoptilolite (Na- type) is investigated. Firstly clinoptilolite is applied in different processes in chrome tannage. In addition, interactions between clinoptilolite with different tanning agents such as vegetable, wet-white, combine are searched. The effects of Na-clinoptilolite on physical and chemical properties of the leathers are determined. After the retanning and greasing processes the leathers colours are measured by Minolta 508d spectrofotometer. Tensile strength, elongation at break, tear resistance, stitch tear resistance and softimeter softness tests are applied to the leather samples. Some of the chemical tests are applied such as determination of sulphated total ash, water soluble ash, chromium, pH, Si, Al, soluble substance in dichloremetane and hide substance. The results of the physical and chemical tests are explained using double variance analysis, duncan and t tests and Fisher PLSD test

    Türkiye’de belediye personel ve yöneticilerinin hizmet içi eğitim sorunu ve çözümleri üzerine bir değerlendirme

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    Özet Bu çalışmanın konusunu, Türkiye’deki belediye personel ve yöneticilerinde görülen hizmet içi eğitim eksikliği ve bu konuda yaşanan çeşitli sorunlar oluşturmaktadır. Çalışmanın temel konusunu daha iyi açıklayabilmek için öncelikle hizmet içi eğitim kavramsal olarak incelenmiştir. Hizmet içi eğitim kavramsal ve teorik olarak tanımlandıktan sonra belediyelere yönelik hizmet içi eğitimin yasal dayanakları ve bu kurumlara yönelik hizmet içi eğitim programları düzenleyen kurum ve kuruluşların son yıllardaki eğitim çalışmaları üzerinde durulmuştur. Çalışmanın ilerleyen kısımda ise, Türkiye’de belediyelerde yaşanan hizmet içi sorununu daha somut verilerle ortaya koyabilmek amacıyla konuya ilişkin yapılmış önemli alan araştırmaları incelenmiştir. Bu alan çalışmalarından bazıları kapsam açısından geniş oldukları için Türkiye’deki çoğu belediyenin yaşadığı hizmet içi eğitim sorunlarına yönelik önemli veriler içermektedir. Bu çalışmaların sonuçlarına göre belediyelerde yaşanan hizmet içi sorununun genel çerçevesi çizilerek, sorunlarla ilgili ortak bulgular analiz edilmeye çalışılmıştır. Çalışmanın sonuç kısmında ise eldeki somut veriler ve eğitim ihtiyaçları doğrultusunda çizilen çerçeve yardımıyla, belediyelerde yaşanan hizmet içi eğitim sorunun çözümüne yönelik organizasyonel ve küçük yasal düzenlemeler konusunda bir takım önerilerde bulunulmuştur. Abstract The subject of this study is the lack of in-service training which is seen in municipal staff and managers and various problems experienced on this subject. Firstly in-service training examined conceptually to explain main subject of study better. After in-service training is defined both conceptual and theoretical, legal support of in-service training for municipalities. It is focused on the recent studies of corporations and institutions which organize in-service training for such kind of institutions. In later part of study, with the aim of expressing in-service training problem in municipality in turkey with more concrete data important studies made on subject were examined. As some of field surveys are detailed in content they have important info for many municipalities in turkey. According to results of studies, by drawing the general framework of problems in service training it is tried to analyze common findings about problems. In conclusion part of study with the help of framework about training need and concrete data for solving the in service training problems, some advices were given about legal layout
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