Relationship of some risk factors and symptoms in patients with acute coronary syndrome

Acute coronary syndrome (ACS) is one of the major causes of death in the worldwide. Clinical manifestations are different. So it's necessary to have knowledge about the types of symptoms experienced by patients with ACS. This study was performed to assay the Relationship of some risk factors and symptoms in patients with acute coronary syndrome. This cross-sectional study, were studied 294 patients with acute coronary syndrome at least 24 hours after admission had survived. Data was collected by a questionnaire that included demographic data form and check list of some symptoms and history of risk factors. There was a significant relationship between STEMI with vomiting (OR=1.94) and anxiety (OR=1.83) and UA with vomiting (OR=0.42). Between sex with weakness (OR=2.29) and anxiety (OR=1.82), diabetes with dyspenea (OR=1.8), weakness (OR=1.02) and tinnitus (OR=2.06) and hyperlipidemia with weakness (OR=2.35) and tinnitus (OR=2.49) was available significant difference. The findings of this study indicate that the appearance of symptoms of acute coronary syndrome were different as for ECG changes and risk factors, and more focused on those symptoms that they are common with any other diseases. Since, many of the symptoms of acute coronary syndrome can be potentially dangerous and life threatening, accurate diagnosis and timely action is crucial for the patients

Effect of the timing of initial feeding on growth and survival of Persian sturgeon (Acipenser persicus) larvae

Effect of the timing of first feeding (9, 10, 11, 12 and 13 days post hatch) with a live food (Artemia naupli) on Persian sturgeon was examined at 17.7±0.8 and 18.1±0.4°C. The results showed that the timing of first feeding affected on weight, length, length-weight ratio and specific growth rate, but one day delay in the timing of initial feeding doesn't affect on the survival and two days delay in the timing of initial feeding doesn't affect on the condition factor. Results of this research showed that some factors such as weight, length, length-weight ratio and specific growth rate, are more suitable than survival and condition factor for exhibiting of effects of delay in the starting time of initial feeding in Persian sturgeon fish larvae. Thus it is better that the initial feeding of Persian sturgeon at 17.7±0.8 and 18.1 ±0.4°C started on 12 and 9 days after hatching, respectively, as well as more delay in initiating exogenous feeding has negative effects on growth of larvae

Effectiveness of light pressure stroking massage on pain and fatigue of patients after coronary artery bypass graft surgery-A randomized clinical trial

زمینه و هدف: درد و خستگی از مشکلات شایع بعد از عمل بیماران تحت جراحی پیوند عروق کرونر می باشد. هدف از این مطالعه تعیین تأثیر ماساژ درمانی بر شدت درد و خستگی بعد از عمل بیماران تحت جراحی پیوند عروق کرونر بوده است. روش بررسی: در این مطالعه کارآزمایی بالینی تصادفی سازی شده، تعداد 72 نفر بیمار تحت عمل جراحی قرارگرفته عروق کرونر در بیمارستان شهید چمران شهر اصفهان، انتخاب شدند و بطور تصادفی در دو گروه مداخله و شاهد قرار گرفتند. بیماران گروه مداخله (36 نفر)، ماساژ استروک سطحی 20 دقیقه ای به مدت 4 جلسه در 4 روز پیاپی در روزهای 3 تا 6 بعد از عمل جراحی دریافت کردند و بیماران گروه شاهد تنها مراقبت های روتین را دریافت نمودند. متغیرهای درد و خستگی قبل و بعد از مداخله با استفاده از مقیاس قیاسی دیداری ثبت شدند. یافته ها: نتایج نشان داد که اختلاف معنی داری بین شدت درد و خستگی در دو گروه مداخله و شاهد بعد از انجام مداخله وجود داشته است (0/001>P). بطوریکه کاهش میانگین شدت درد و خستگی از روز اول تا چهارم بعد از عمل در گروه مداخله بیشتر از گروه شاهد بود. نتیجه گیری: استفاده از ماساژ استروک سطحی می تواند باعث کاهش درد و خستگی بعد از عمل بیماران تحت جراحی پیوند عروق کرونر شود و با توجه به سادگی و کم هزینه بودن این روش، شاید بتواند به عنوان مکمل مناسبی برای دارودرمانی و مداخلات بعد از عمل در این بیماران مورد استفاده قرار گیرد

Hopes and Hurdles of Employing Mesenchymal Stromal Cells in the Treatment of Cardiac Fibrosis

Excessive cardiac fibrosis plays a crucial role in almost all types of heart disease. Generally, cardiac fibrosis is a scarring process triggered in response to stress, injury, or aging and is characterized by the accumulation of activated myofibroblasts that deposit high levels of extracellular matrix proteins in the myocardium. While it is beneficial for cardiac repair in the short term, it can also result in pathological remodeling, tissue stiffening, and cardiac dysfunction, contributing to the progression of heart failure, arrhythmia, and sudden cardiac death. Despite its high prevalence, there is a lack of effective and safe therapies that specifically target myofibroblasts to inhibit or even reverse pathological cardiac fibrosis. In the past few decades, cell therapy has been under continuous evaluation as a potential treatment strategy, and several studies have shown that transplantation of mesenchymal stromal cells (MSCs) can reduce cardiac fibrosis and improve heart function. Mechanistically, it is believed that the heart benefits from MSC therapy by stimulating innate anti-fibrotic and regenerative reactions. The mechanisms of action include paracrine signaling and cell-to-cell interactions. In this review, we provide an overview of the anti-fibrotic properties of MSCs and approaches to enhance them and discuss future directions of MSCs for the treatment of cardiac fibrosis

Hopes and Hurdles of Employing Mesenchymal Stromal Cells in the Treatment of Cardiac Fibrosis

Excessive cardiac fibrosis plays a crucial role in almost all types of heart disease. Generally, cardiac fibrosis is a scarring process triggered in response to stress, injury, or aging and is characterized by the accumulation of activated myofibroblasts that deposit high levels of extracellular matrix proteins in the myocardium. While it is beneficial for cardiac repair in the short term, it can also result in pathological remodeling, tissue stiffening, and cardiac dysfunction, contributing to the progression of heart failure, arrhythmia, and sudden cardiac death. Despite its high prevalence, there is a lack of effective and safe therapies that specifically target myofibroblasts to inhibit or even reverse pathological cardiac fibrosis. In the past few decades, cell therapy has been under continuous evaluation as a potential treatment strategy, and several studies have shown that transplantation of mesenchymal stromal cells (MSCs) can reduce cardiac fibrosis and improve heart function. Mechanistically, it is believed that the heart benefits from MSC therapy by stimulating innate anti-fibrotic and regenerative reactions. The mechanisms of action include paracrine signaling and cell-to-cell interactions. In this review, we provide an overview of the anti-fibrotic properties of MSCs and approaches to enhance them and discuss future directions of MSCs for the treatment of cardiac fibrosis

Comparing the patterns of hypertension and type 2 diabetes mellitus in patients with colorectal cancer

Background: Type 2 diabetes mellitus (DM) and hypertension are worldwide epidemic. Colorectal cancer (CRC) is the most prevalent gastrointestinal cancer in Iran. Prevalence of type 2 diabetes mellitus and hypertension in the patients with colorectal cancer had not reported in Iran, before this study. Methods: Overall, 2570 individual-year follow-ups were conducted for 1127 patients with colorectal cancer. For diagnosis of type 2 diabetes mellitus, fasting blood sugar and glycosylated hemoglobin tests were used and for that of hypertension, blood pressure was measured in two turns. The descriptive indices were calculated and the mean and median survivals, from colorectal cancer diagnosis time, were calculated using survival analysis and the comparison among survival times was done through log-rank test. Stata12 software was used for data analysis. Findings: The prevalences of hypertension and type 2 diabetes mellitus in the patients with colorectal cancer were 13.38 (95 CI: 11.1-15.8) and 8.69 (95 CI: 7.0-10.7), respectively. Median survival time in patients with hypertension and diabetes mellitus were 8.52 and 4.90 years, respectively. According to log-rank test, no significant difference was observed between the survival time of patients with colorectal cancer suffering from hypertension and type 2 diabetes mellitus. Conclusion: The obtained findings in this study indicate that survival time in patients with type 2 diabetes mellitus is less than those with hypertension; but two metabolic diseases have same effect on survival rate of the patients with colorectal cancer. © 2014, Isfahan University of Medical Sciences(IUMS). All rights reserved

The Simultaneous Impacts of Seasonal Weather and Solar Conditions on PV Panels Electrical Characteristics

Solar energy usage is thriving day by day. These solar panels are installed to absorb solar energy and produce electrical energy. As a result, the efficiency of solar panels depends on different environmental factors, namely, air temperature, dust (aerosols and accumulated dust), and solar incidence, and photovoltaic panel angles. The effects of real conditions factors on power and efficiency of photovoltaic panels are studied in this paper through testing the panel in real environmental tests. To study the mentioned parameters precisely, two panels with different angles are used. The case study is regarding a region of Tehran, Iran, in summer and winter seasons. The results show that panel efficiency during winter is higher than summer due to air temperature decrement. It is discovered that among air pollutants, Al and Fe have the most share in polluting the air that affect the photovoltaic efficiency. Moreover, measuring the accumulated dust on the panels shows more amount in winter in comparison with summer. The important point in studying the effect of tilt angle is that inconformity between solar incidence and photovoltaic panel angles would result in solar radiation absorption and eventually panel efficiency loss and also, photovoltaic panel installation angle would affect the amount of dust deposited on its surface.© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).fi=vertaisarvioitu|en=peerReviewed