135 research outputs found

    Responses of seasonal indicators to extreme droughts in southwest China

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    Significant impact of extreme droughts on human society and ecosystem has occurred in many places of the world, for example, Southwest China (SWC). Considerable research concentrated on analyzing causes and effects of droughts in SWC, but few studies have examined seasonal indicators, such as variations of surface water and vegetation phenology. With the ongoing satellite missions, more and more earth observation data become available to environmental studies. Exploring the responses of seasonal indicators from satellite data to drought is helpful for the future drought forecast and management. This study analyzed the seasonal responses of surface water and vegetation phenology to drought in SWC using the multi-source data including Seasonal Water Area (SWA), Permanent Water Area (PWA), Start of Season (SOS), End of Season (EOS), Length of Season (LOS), precipitation, temperature, solar radiation, evapotranspiration, the Palmer Drought Severity Index (PDSI), the Normalized Difference Vegetation Index (NDVI), the Enhanced Vegetation Index (EVI), Gross Primary Productivity (GPP) and data from water conservancy construction. The results showed that SWA and LOS effectively revealed the development and recovery of droughts. There were two obvious drought periods from 2000 to 2017. In the first period (from August 2003 to June 2007), SWA decreased by 11.81% and LOS shortened by 5 days. They reduced by 21.04% and 9 days respectively in the second period (from September 2009 to June 2014), which indicated that there are more severe droughts in the second period. The SOS during two drought periods delayed by 3~6 days in spring, while the EOS advanced 1~3 days in autumn. All of PDSI, SWA and LOS could reflect the period of droughts in SWC, but the LOS and PDSI were very sensitive to the meteorological events, such as precipitation and temperature, while the SWA performed a more stable reaction to drought and could be a good indicator for the drought periodicity. This made it possible for using SWA in drought forecast because of the strong correlation between SWA and drought. Our results improved the understanding of seasonal responses to extreme droughts in SWC, which will be helpful to the drought monitoring and mitigation for different seasons in this ecologically fragile region

    The relationship between umbilical cord blood IL-22 level and infantile eczema at 42 days

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    BackgroundThe occurrence of eczema is related to helper T 22 (Th22) cytokine disorder, and Th22 mainly secretes interleukin-22 (IL-22). This study aims to investigate the predictive value of umbilical cord blood IL-22 levels on the onset of eczema in infants within 42 days.Study designThe study selected 157 full-term healthy neonates born between September 2020 and May 2021. Cord blood was collected immediately after birth to determine IL-22 levels, and the infants were followed up for 42 days to assess the incidence of eczema.ResultsAmong the 157 infants who completed the 42-day follow-up, 86 developed eczema and 71 did not. The level of IL-22 in the umbilical cord blood of the eczema group was lower than that of the non-eczema group (p < 0.05). Additionally, the incidence of eczema in children whose Family history of allergy was significantly higher than in the group without eczema (p < 0.05). Logistic regression analysis indicated that low cord blood IL-22 levels and a family history of allergies were independent risk factors for eczema (p < 0.05). The ROC curve of cord blood IL-22 levels and infant eczema showed that the cut-off value is 36.362 pg/ml, the area under the curve (AUC) is 0.613, the standard error is 0.045, the 95% CI is 0.526–0.701, the sensitivity is 63.4%, and the specificity is 57.0%. Therefore, there is a certain correlation between cord blood IL-22 levels and the incidence of infant eczema.ConclusionsLow IL-22 levels in umbilical cord blood may be linked to the development of infant eczema within 42 days, indicating a potential predictive value, although this value appears to be limited

    A Priori Error Estimation of Physics-Informed Neural Networks Solving Allen--Cahn and Cahn--Hilliard Equations

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    This paper aims to analyze errors in the implementation of the Physics-Informed Neural Network (PINN) for solving the Allen--Cahn (AC) and Cahn--Hilliard (CH) partial differential equations (PDEs). The accuracy of PINN is still challenged when dealing with strongly non-linear and higher-order time-varying PDEs. To address this issue, we introduce a stable and bounded self-adaptive weighting scheme known as Residuals-RAE, which ensures fair training and effectively captures the solution. By incorporating this new training loss function, we conduct numerical experiments on 1D and 2D AC and CH systems to validate our theoretical findings. Our theoretical analysis demonstrates that feedforward neural networks with two hidden layers and tanh activation function effectively bound the PINN approximation errors for the solution field, temporal derivative, and nonlinear term of the AC and CH equations by the training loss and number of collocation points

    Shorter TCR β-Chains Are Highly Enriched During Thymic Selection and Antigen-Driven Selection

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    The adaptive immune system uses several strategies to generate a repertoire of T cell receptors (TCR) with sufficient diversity to recognize the universe of potential pathogens. However, it remains unclear how differences in the T cell receptor (TCR) contribute to heterogeneity in T cell state. In this study, we used polychromatic flow cytometry to isolate highly pure CD4+/CD8+ naive and memory T cells, and applied deep sequencing to characterize corresponding TCR β-chain (TCRβ) complementary-determining region 3 (CDR3) repertoires. We find that shorter TCRβ CDR3s with fewer insertions were highly enriched during thymic selection. Antigen-experienced T cells (memory T cells) harbor shorter CDR3s vs. naive T cells. Moreover, the public TCRβ CDR3 clonotypes within cell subsets or interindividual tend to have shorter CDR3 length and a significantly larger size compared with “private” clonotypes. Taken together, shorter CDR3s highly enriched during thymic selection and antigen-driven selection, and further enriched in public T-cell responses. These results indicated that it may be evolutionary pressures drive short CDR3s to recognize most of antigen in nature

    Deregulation of Sucrose-Controlled Translation of a bZIP-Type Transcription Factor Results in Sucrose Accumulation in Leaves

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    Sucrose is known to repress the translation of Arabidopsis thaliana AtbZIP11 transcript which encodes a protein belonging to the group of S (S - stands for small) basic region-leucine zipper (bZIP)-type transcription factor. This repression is called sucrose-induced repression of translation (SIRT). It is mediated through the sucrose-controlled upstream open reading frame (SC-uORF) found in the AtbZIP11 transcript. The SIRT is reported for 4 other genes belonging to the group of S bZIP in Arabidopsis. Tobacco tbz17 is phylogenetically closely related to AtbZIP11 and carries a putative SC-uORF in its 5′-leader region. Here we demonstrate that tbz17 exhibits SIRT mediated by its SC-uORF in a manner similar to genes belonging to the S bZIP group of the Arabidopsis genus. Furthermore, constitutive transgenic expression of tbz17 lacking its 5′-leader region containing the SC-uORF leads to production of tobacco plants with thicker leaves composed of enlarged cells with 3–4 times higher sucrose content compared to wild type plants. Our finding provides a novel strategy to generate plants with high sucrose content

    Soil moisture and soil properties estimation in the Community Land Model with synthetic brightness temperature observations

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    The Community Land Model (CLM) includes a large variety of parameterizations, also for flow in the unsaturated zone and soil properties. Soil properties introduce uncertainties into land surface model predictions. In this paper, soil moisture and soil properties are updated for the coupled CLM and Community Microwave Emission Model (CMEM) by the Local Ensemble Transform Kalman Filter (LETKF) and the state augmentation method. Soil properties are estimated through the update of soil textural properties and soil organic matter density. These variables are used in CLM for predicting the soil moisture retention characteristic and the unsaturated hydraulic conductivity, and the soil texture is used in CMEM to calculate the soil dielectric constant. The following scenarios were evaluated for the joint state and parameter estimation with help of synthetic L-band brightness temperature data assimilation: (i) the impact of joint state and parameter estimation; (ii) updating of soil properties in CLM alone, CMEM alone or both CLM and CMEM; (iii) updating of soil properties without soil moisture update; (iv) the observation localization of LETKF. The results show that the characterization of soil properties through the update of textural properties and soil organic matter density can strongly improve with assimilation of brightness temperature data. The optimized soil properties also improve the characterization of soil moisture, soil temperature, actual evapotranspiration, sensible heat flux, and soil heat flux. The best results are obtained if the soil properties are updated only. The coupled CLM and CMEM model is helpful for the parameter estimation. If soil properties are biased, assimilation of soil moisture data with only state updates increases the root mean square error for evapotranspiration, sensible heat flux, and soil heat flux

    Land use change and climate variation in the Three Gorges Reservoir Catchment from 2000 to 2015 based on the Google Earth Engine

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    Possible environmental change and ecosystem degradation have received increasing attention since the construction of Three Gorges Reservoir Catchment (TGRC) in China. The advanced Google Earth Engine (GEE) cloud-based platform and the large number of Geosciences and Remote Sensing datasets archived in GEE were used to analyze the land use and land cover change (LULCC) and climate variation in TGRC. GlobeLand30 data were used to evaluate the spatial land dynamics from 2000 to 2010 and Landsat 8 Operational Land Imager (OLI) images were applied for land use in 2015. The interannual variations in the Land Surface Temperature (LST) and seasonally integrated normalized difference vegetation index (SINDVI) were estimated using Moderate Resolution Imaging Spectroradiometer (MODIS) products. The climate factors including air temperature, precipitation and evapotranspiration were investigated based on the data from the Global Land Data Assimilation System (GLDAS). The results indicated that from 2000 to 2015, the cultivated land and grassland decreased by 2.05% and 6.02%, while the forest, wetland, artificial surface, shrub land and waterbody increased by 3.64%, 0.94%, 0.87%, 1.17% and 1.45%, respectively. The SINDVI increased by 3.209 in the period of 2000-2015, while the LST decreased by 0.253 °C from 2001 to 2015. The LST showed an increasing trend primarily in urbanized area, with a decreasing trend mainly in forest area. In particular, Chongqing City had the highest LST during the research period. A marked decrease in SINDVI occurred primarily in urbanized areas. Good vegetation areas were primarily located in the eastern part of the TGRC, such as Wuxi County, Wushan County, and Xingshan County. During the 2000–2015 period, the air temperature, precipitation and evapotranspiration rose by 0.0678 °C/a, 1.0844 mm/a, and 0.4105 mm/a, respectively. The climate change in the TGRC was influenced by LULCC, but the effect was limited. What is more, the climate change was affected by regional climate change in Southwest China. Marked changes in land use have occurred in the TGRC, and they have resulted in changes in the LST and SINDVI. There was a significantly negative relationship between LST and SINDVI in most parts of the TGRC, especially in expanding urban areas and growing forest areas. Our study highlighted the importance of environmental protection, particularly proper management of land use, for sustainable development in the catchment

    <italic>POD</italic>: A Parallel Outlier Detection Algorithm Using Weighted kNN

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    Outlier detection algorithms based on k{k} nearest neighbors ( k{k} NN) can effectively find outliers from massive data, but most algorithms are difficult to adapt to high-dimensional data sets. In order to highlight the importance of attributes in k{k} nearest neighbors, we propose a weighted k{k} NN query method, which uses the Z-order curve to find the k{k} NN. The method first applies information entropy to calculate each attribute weight, and then uses the Z-order curve to encode high-dimensional data into Z{Z} -value. The weighted k{k} NN of each object are searched according to its Z{Z} -value. Meanwhile, a novel outlier detection algorithm is presented based on the minimum distance and average distance between each object and its weighted k{k} NN. On this basis, we propose a parallel outlier detection algorithm called POD to improve the efficiency of the outlier detection. Finally, we implement and evaluate POD algorithm on a 10-nodes Hadoop cluster, on which synthetic and UCI standard data are tested. Experimental results show that POD achieves high performance in terms of effectiveness, scalability and extensibility
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