10,314 research outputs found
Coherent population trapping in a dressed two-level atom via a bichromatic field
We show theoretically that by applying a bichromatic electromagnetic field,
the dressed states of a monochromatically driven two-level atom can be pumped
into a coherent superposition termed as dressed-state coherent population
trapping. Such effect can be viewed as a new doorknob to manipulate a two-level
system via its control over dressed-state populations. Application of this
effect in the precision measurement of Rabi frequency, the unexpected
population inversion and lasing without inversion are discussed to demonstrate
such controllability.Comment: 14 pages, 6 figure
Plasmon assisted transmission of high dimensional orbital angular momentum entangled state
We present an experimental evidence that high dimensional orbital angular
momentum entanglement of a pair of photons can be survived after a
photon-plasmon-photon conversion. The information of spatial modes can be
coherently transmitted by surface plasmons. This experiment primarily studies
the high dimensional entangled systems based on surface plasmon with
subwavelength structures. It maybe useful in the investigation of spatial mode
properties of surface plasmon assisted transmission through subwavelength hole
arrays.Comment: 7 pages,6 figure
Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions
© 2014, The Author(s).Research in the past two decades has generated unequivocal evidence that host genetic variations substantially account for the heterogeneous outcomes following human immunodeficiency virus type 1 (HIV-1) infection. In particular, genes encoding human leukocyte antigens (HLA) have various alleles, haplotypes, or specific motifs that can dictate the set-point (a relatively steady state) of plasma viral load (VL), although rapid viral evolution driven by innate and acquired immune responses can obscure the long-term relationships between HLA genotypes and HIV-1-related outcomes. In our analyses of VL data from 521 recent HIV-1 seroconverters enrolled from eastern and southern Africa, HLA-A*03:01 was strongly and persistently associated with low VL in women (frequency = 11.3 %, P  0.50). In a reduced multivariable model, age, sex, geography (clinical sites), previously identified HLA factors (HLA-B*18, B*45, B*53, and B*57), and the interaction term for female sex and HLA-A*03:01 collectively explained 17.0 % of the overall variance in geometric mean VL over a 3-year follow-up period (P < 0.0001). Multiple sensitivity analyses of longitudinal and cross-sectional VL data yielded consistent results. These findings can serve as a proof of principle that the gap of âmissing heritabilityâ in quantitative genetics can be partially bridged by a systematic evaluation of sex-specific associations
Recurrent geomagnetic storms and relativistic electron enhancements in the outer magnetosphere: ISTP coordinated measurements
New, coordinated measurements from the International Solar-Terrestrial Physics (ISTP) constellation of spacecraft are presented to show the causes and effects of recurrent geomagnetic activity during recent solar minimum conditions. It is found using WIND and POLAR data that even for modest geomagnetic storms, relativistic electron fluxes are strongly and rapidly enhanced within the outer radiation zone of the Earth\u27s magnetosphere. Solar wind data are utilized to identify the drivers of magnetospheric acceleration processes. Yohkoh solar soft X-ray data are also used to identify the solar coronal holes that produce the high-speed solar wind streams which, in turn, cause the recurrent geomagnetic activity. It is concluded that even during extremely quiet solar conditions (sunspot minimum) there are discernible coronal holes and resultant solar wind streams which can produce intense magnetospheric particle acceleration. As a practical consequence of this Sun-Earth connection, it is noted that a long-lasting E\u3e1MeV electron event in late March 1996 appears to have contributed significantly to a major spacecraft (Anik E1) operational failure
Why the braking indices of young pulsars are less than 3?
In this letter we discuss two possible reasons which cause the observed
braking indices n of young radio pulsars to be smaller than 3: (a) the evolving
spin-down model of the magnetic field component increases with
time; (b) the extrinsic braking torque model in which the tidal torques exerted
on the pulsar by the fallback disk, and carries away the spin angular momentum
from the pulsar. Based on some simple assumptions, we derive the expression of
the braking indices, and calculate the spin-down evolutionary tracks of pulsars
for different input parameters.Comment: 4 pages, 3 figures, accepted for publication in A&A Letter
Dynamical chaos and power spectra in toy models of heteropolymers and proteins
The dynamical chaos in Lennard-Jones toy models of heteropolymers is studied
by molecular dynamics simulations. It is shown that two nearby trajectories
quickly diverge from each other if the heteropolymer corresponds to a random
sequence. For good folders, on the other hand, two nearby trajectories may
initially move apart but eventually they come together. Thus good folders are
intrinsically non-chaotic. A choice of a distance of the initial conformation
from the native state affects the way in which a separation between the twin
trajectories behaves in time. This observation allows one to determine the size
of a folding funnel in good folders. We study the energy landscapes of the toy
models by determining the power spectra and fractal characteristics of the
dependence of the potential energy on time. For good folders, folding and
unfolding trajectories have distinctly different correlated behaviors at low
frequencies.Comment: 8 pages, 9 EPS figures, Phys. Rev. E (in press
Down-regulation of miR-27a might inhibit proliferation and drug resistance of gastric cancer cells
<p>Abstract</p> <p>Aims</p> <p>Here we aimed to firstly investigate the role of miR-27a in proliferation and multidrug resistance of gastric cancer cells.</p> <p>Methods</p> <p>The role of miR-27a in gastric cancer cells was detected using MTT assay, soft agar assay, flow cytometry assay, nude mice assay, real-time PCR, western blot and reporter gene assay, etc.</p> <p>Results</p> <p>Down-regulation of miR-27a could inhibit porliferation of gastric cancer cells in vitro and in vivo. Down-regulation of miR-27a could also confer sensitivity of drugs on gastric cancer cells, and might increase accumulation and decrease releasing amount of adriamycin in gastric cancer cells. Down-regulation of miR-27a could significantly decrease the expression of P-glycoprotein and the transcriptional activity of cyclin D1, and up-regulate the expression of p21.</p> <p>Conclusions</p> <p>MiR-27a might play important roles in porliferation and drug resistance of gastric cancer. MiR-27a might be considered as a useful target for cancer therapy.</p
Manipulating infrared photons using plasmons in transparent graphene superlattices
Superlattices are artificial periodic nanostructures which can control the
flow of electrons. Their operation typically relies on the periodic modulation
of the electric potential in the direction of electron wave propagation. Here
we demonstrate transparent graphene superlattices which can manipulate infrared
photons utilizing the collective oscillations of carriers, i.e., plasmons of
the ensemble of multiple graphene layers. The superlattice is formed by
depositing alternating wafer-scale graphene sheets and thin insulating layers,
followed by patterning them all together into 3-dimensional
photonic-crystal-like structures. We demonstrate experimentally that the
collective oscillation of Dirac fermions in such graphene superlattices is
unambiguously nonclassical: compared to doping single layer graphene,
distributing carriers into multiple graphene layers strongly enhances the
plasmonic resonance frequency and magnitude, which is fundamentally different
from that in a conventional semiconductor superlattice. This property allows us
to construct widely tunable far-infrared notch filters with 8.2 dB rejection
ratio and terahertz linear polarizers with 9.5 dB extinction ratio, using a
superlattice with merely five graphene atomic layers. Moreover, an unpatterned
superlattice shields up to 97.5% of the electromagnetic radiations below 1.2
terahertz. This demonstration also opens an avenue for the realization of other
transparent mid- and far-infrared photonic devices such as detectors,
modulators, and 3-dimensional meta-material systems.Comment: under revie
Gravitational Leptogenesis and Neutrino Mass Limit
Recently Davoudiasl {\it et al} \cite{steinhardt} have introduced a new type
of interaction between the Ricci scalar and the baryon current ,
and proposed a mechanism for baryogenesis, the
gravitational baryogenesis. Generally, however, vanishes in
the radiation dominated era. In this paper we consider a generalized form of
their interaction, and study again the possibility
of gravitational baryo(lepto)genesis. Taking , we will show
that does not vanish and the
required baryon number asymmetry can be {\it naturally} generated in the early
universe.Comment: 4 page
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