10 research outputs found
Former à s’informer : développer l’esprit critique ! Comment éduquer et accompagner les adolescents et les jeunes adultes dans l’univers médiatique contemporain pour les aider à grandir ?
- Author
- Publication venue
- Mediat Rhône-Alpes
- Publication date
- Field of study
Les contenus pédagogiques ont été réalisés dans le cadre du projet Former des médiateurs EMI pour adolescents et jeunes adultes, déposé en 2020 par l’Enssib et l’Inspé Université Claude Bernard Lyon 1. Ce projet s’inscrit dans le Plan EMI développé et financé par le Ministère de la Culture
Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial
- Author
- Abaterusso Cataldo
- Abdul Kadir Khalid
- Abrahamovych Orest
- Acharya Shamasunder
- Acosta Idalia
- Adam Noor
- Adams Luthando
- Adawi Faiad
- Adolphe Allen
- Ahmad Ghazali
- Ahmed Azazuddin
- Ahmed Ziauddin
- Ahn Kyu Jeung
- Alcantara-Gonzalez Altagracia Aurora
- Aldrete Jorge
- Ali Norhaliza Mohd
- Almirall Jaume
- Alscher Mark
- Alvarado Odilon
- Alvarez German
- Alvarisqueta Andres
- Amin Mohammad
- Amodeo Celso
- Andress Dennis L
- Annand Andrew
- Antunes Ferreira Manuel Anibal
- Anzai Jiichi
- Apostolou Theofanis
- Arauz-Pacheco Carlos
- Arciszewska Malgorzata
- Argoud Georges
- Arif Ahmed
- Aronson Ronnie
- Arrieta Lezama Javier
- Assefi Ali
- Ato Keita
- Atray Naveen
- Awua-Larbi Stella
- Aziz Nor Azizah
- Azuma Nobuyuki
- Bai Liqun
- Bailey Gordon
- Bajaj Harpreet Singh
- Bakdash Wa'El
- Baker John
- Baker Penelope
- Bako Gabriel
- Bakris George
- Bakris George
- Bansal Shweta
- Bar-Dayan Yosefa
- Bardymova Tatiana
- Barendregt Jnm
- Barengolts Elena
- Bartaskova Dagmar
- Bau Cho-Tsan
- Bayliss George
- Beddhu Srinivasan
- Bedros Fadi
- Belledonne Mario
- Belo Diogo
- Bentsianov Marie
- Bhargava Anuj
- Bhorat Qasim
- Bieler Tasso
- Birne Rita
- Blagoveshchenskaya Olga
- Bloom Scott
- Blumenthal Samuel
- Bochicchio-Ricardelli Tomasso
- Bock Andreas
- Bohm Guillermo
- Boiskin Mark
- Bonet Sol Josep
- Borges Joao Lindolfo
- Bowman-Stroud Cynthia
- Brantley Roman
- Bressler Peter
- Brown Eric
- Brunati Chiara
- Brusco Osvaldo
- Bucek Petr
- Budde Klemens
- Burga Nunez Jose
- Burgos-Calderon Rafael
- Busch Robert
- Butt Salman
- Cabrita Antonio
- Calderon Ortiz Ricardo
- Calderon Ticona Jorge
- Calero Gonzalez Francesca
- Cangiano Jose
- Capasso Giovambattista
- Carranza-Madrigal Jaime
- Castillo Alvaro
- Castro-Alonso Cristina
- Cathcart Harold
- Cercato Cintia
- Cha Dae-Ryong
- Chan Doris
- Chatha Rupi
- Chen Ching-Chu
- Chen Jung-Fu
- Chen Nan
- Cheung Siu Fai
- Chevaile-Ramos Jose
- Chew Wong Alfredo
- Chmelickova Hana
- Cho Ho Chan
- Cho Yong-Wook
- Choi Kyung Mook
- Choi Moon-Gi
- Chow Stephen
- Christofides Elena
- Chu Chih-Hsun
- Chuang Peale
- Chung Choon Hee
- Ciechanowski Kazimierz
- Cigarran Guldris Secundino
- Coetzee Kathleen
- Cohen Josef
- Combe Christian
- Comulada-Rivera Angel
- Conte Giuseppe
- Cooke Duncan
- Correa-Rotter Ricardo
- Costa e Forti Adriana
- Cournoyer Serge
- Cruz Lucita
- Cusumano Ana
- D'Avila Domingos
- Dahl Neera
- Danin Vargas Alfredo
- Daoud Deeb
- Davis Tim
- de Arteaga Javier
- De Cosmo Salvatore
- De la Calle Gilda
- de Lourdes Noronha Irene
- de Zeeuw Dick
- Deboni Luciane
- Delgado-Butron Cesar
- Dellanna Frank
- Desai Sachin
- Dextre Espinoza Augusto
- Ding Guohua
- Ding Xiaoqiang
- Distiller Larry
- Dixon Brad
- Doo-Man Kim
- Doshi Ankur
- Draibe Sergio
- Dudar Iryna
- Dulude Emily
- Duma Livia
- Dussol Bertrand
- Egido Jesus
- Egstrup Kenneth
- El-Shahawy Mohamed
- Elbert Alicia
- Elder John
- Eliaschewitz Freddy
- Ellis Graham
- Endre Zoltan
- Esnault Vincent
- Esposito Ciro
- Essaian Ashot
- Eustace Joseph
- Fang Michael
- Farfan-Aspilcueta Julio
- Farias Eduardo
- Fekete Jozef
- Felicio Joao
- Fellstrom Bengt
- Fernandez Fresnedo Gema
- Fernandez Giraldez Elvira
- Fernando Ronald
- Fitz-Patrick David
- Flores Jose
- Foo Marjorie Wai Yin
- Fraenkel Margaret
- Fraige Filho Fadlo
- Frajewicki Victor
- Frias Juan
- Fried Linda
- Fu Ping
- Fu Shuxia
- Fujii Shinya
- Fujita Akira
- Fulopova Alla
- Fung Samuel
- Fung Yin Khet
- Furuya Ryuichi
- Fushtey Ivan
- Galan Antonio
- Galfre Andrea
- Galindo Ramos Eugenia
- Gallagher Martin
- Galphin Claude
- Galushchak Olga
- Gansevoort Ronald
- Gaona Raul
- Garcia Mendez Isabel
- Gesualdo Loreto
- Gilbert John
- Gillard Pieter
- Gnudi Luigi
- Godoy Gonzalo
- Goh Bak Leong
- Goldfarb David
- Golestaneh Laden
- Goluch Richard
- Gonzalez Gonzalez Jose
- Gonzalez Fernando
- Gonzalez-Galvez Guillermo
- Goto Daisuke
- Gouge Steven
- Goumenos Dimitrios
- Graf Ronald
- Greenwood Gregory
- Greloni Gustavo
- Guadiz Ramon
- Guasch Antonio
- Gundroo Aijaz
- Guo Xiaohui
- Gutierrez Vicente
- Halimi Jean-Michel
- Hall Karen
- Hames Melanie
- Hancu Nicolae
- Hanson Lenita
- Hao Chuanming
- Harada Hiroyuki
- Hashiguchi Yasuhiro
- Hassan Wan Hasnul Halimi Wan
- Hasslacher Christoph
- Heerspink Hiddo J L
- Hellberg Olof
- Herman Lee
- Hernandez-Jaras Julio
- Herrada Orue Benjamin
- Herrero Calvo Jose
- Hershon Kenneth
- Hirano Fuminori
- Honova Vaclava
- Horwitz Edward
- Hou Fan-Fan
- Hou Fanfan
- Hougardy Jean
- Huang Chien-Ning
- Hugo Christian
- Hussein Zanariah
- Iehara Noriyuki
- Iitsuka Tadashi
- Ijaz Adeel
- Ikeda Naoko
- Imura Mitsuo
- Inoue Toshihiko
- Ionutiu Lavinia
- Ishikawa Kazuo
- Ishiko Tamayo
- Israel Ezra
- Itabashi Naoki
- Ivanova Svetlana
- Iwaoka Hideaki
- Jabbour Serge
- Jadoul Michel
- Jamal Aamir
- James Sam
- Jang Hak Chul
- Jardula Michael
- Jere Charles
- Ji Linong
- Jia Weiping
- Jiang Ju-Ying
- John Rekha
- Jolly Shivinder
- Jones Audrey
- Joshi Sucharit
- Joshi Sudhir
- Juncos Luis
- Kalender Betul
- Kalirao Paramjit
- Kalra Phillip
- Kanai Hidetoshi
- Kaneko Shizuka
- Kantola Ilkka
- Kantor Samuel
- Karim Shahana
- Karonova Tatiana
- Karpova Irina
- Kashihara Naoki
- Kashine Susumu
- Kayali Zeid
- Keitel Elizete
- Kenis Irina
- Khandwala Hasnain
- Kim Beom Seok
- Kim Byung-Joon
- Kim In-Joo
- Kim Min Seon
- Kim Sang Yong
- Kim Sin-Gon
- Kishimoto Rui
- Kitzman Dalane W
- Kiyosue Arihiro
- Klimontov Vadim
- Klodawska Katarzyna
- Knobler Hilla
- Kobayashi Kunihisa
- Kohan Donald
- Kolenyk Mykola
- Kolesarova Eva
- Kolmakova Elena
- Kon Sui Phin
- Kopyt Nelson
- Korpachev Vadym
- Kosch Christine
- Kostynenko Tetyana
- Kosuge Keiichiro
- Kovesdy Csaba
- Koziolova Natalya
- Kronfli Saeed
- Kumar Jayant
- Kuskalo Petro
- Kuzin Anatoly
- Lahtela Jorma
- Lalwani Tarik
- Lantseva Olga
- Lauro Davide
- Laverman Gozewijn
- Lavin Peter
- Lawrence Mary
- Lee Hyoung Woo
- Lee Jae Hyuk
- Lee Joseph
- Lee Kang-Wook
- Lee Kwan Woo
- Lee Moon-Kyu
- Lee Sang Ah
- Leguizamo-Dimas Aniceto
- Legun Oleg
- Leite Silmara
- Leon-Forero Carlos
- Levin Ellis
- Levine Andrew
- Li Yuxiu
- Liakopoulos Vasilios
- Liberanskaya Natalia
- Lien Yeong-Hau
- Liew Adrian
- Lin Ching-Ling
- Link Michael
- Liss Kenneth
- Liu Bicheng
- Liu Zhangsuo
- Lui Sing Leung
- Luik Peter
- Lunt Helen
- Luo Qun
- Macisaac Richard
- Maddukuri Geetha
- Madero Rovalo Magdalena
- Madu Ivy-Joan
- Maeda Hajime
- Maeda Yoshitaka
- Maffei Laura
- Makan Hemant
- Makino Hirofumi
- Makino Shinya
- Makita Yuichiro
- Maksudova Adelya
- Malberti Fabio
- Mangoo-Karim Roberto
- Mankovskyy Borys
- Manley John
- Marasaev Vyacheslav
- Marder Bradley
- Marino Francesco
- Mark Patrick
- Markell Mariana
- Marques Vidas Maria
- Martins Munoz Judith
- Martynenko Vladimir
- Martynyuk Liliya
- Matsuda Hirofumi
- Matsuhisa Munehide
- Matsutani Akira
- Matta Fontanet Evelyn
- Mavromatidis Konstantinos
- Maxwell Peter
- Mayer Gert
- Mazur Stanislaw
- Mcfadden Christopher
- Mcmurray John J V
- Medina-Santander Boris
- Melish John
- Melnick Joel Z
- Menefee Judson
- Merican Nor Shaffinaz Yusuf Azmi
- Mersey James
- Milagres Rosangela
- Miller Alan
- Miller Michael G
- Miller Steven
- Minasian Raffi
- Minga Todd
- Minguela Pesquera Jose Ignacio
- Mistodie Cristina
- Mitha Essack
- Miyaoka Hiroaki
- Mohamed Mafauzy
- Mok Ji Oh
- Molas Coten Jose Ramon
- Montero Manuel
- Montero Nuria
- Mordovin Viktor
- Moura Neto Jose Andrade
- Moya Hechevarria Jaynier
- Muehlfeld Anja
- Mukasa Koji
- Mulloy Laura
- Munoz Rodrigo
- Muoneke Rosemary
- Nagai Sou
- Nagayama Koji
- Naiker Puvenesvari
- Naka Motoji
- Nakamura Takehiro
- Nakashima Eitaro
- Nakazawa Jun
- Nakhle Samer
- Nam-Goong Il-Seong
- Nammour Michael
- Nappi Felice
- Navarro Gonzalez Juan
- Nazeer Imran
- Necki Miroslaw
- Nesrallah Gihad
- Newman George
- Ni Zhaohui
- Nica Romanita
- Nik Ahmad Nik Nur Fatnoon
- Nimura Toshinori
- Nino-Cruz Jose
- Nishimura Motonobu
- Nowicki Michal
- O'Shaughnessy Andrew
- O'Shea Donal
- Obetkova Ida
- Oczachowska-Kulik Anna
- Oh Tae Keun
- Okamoto Hideki
- Oksa Adrian
- Onishi Yukiko
- Ono Keiko
- Ono Yasuhiro
- Oplustilova Alexandra
- Oroszova Aniko
- Osama Sayed
- Osonoi Takeshi
- Ostergaard Ove
- Ozaki Risa
- Panichi Vincenzo
- Panina Svitlana
- Park Kyong-Soo
- Park Tae-Sun
- Parving Hans-Henrik
- Paschoalin Raphael
- Pascual Julio
- Passadakis Ploumis
- Patel Dipesh
- Pavlova Maria
- Pecoits Filho Roberto
- Peguero-Rivera Alfredo
- Pei Dee
- Pergola Pablo
- Pergola Pablo E
- Perkovic Vlado
- Perlman Alan
- Petit Catherine
- Petr Martin
- Petrica Ligia
- Petrosyan Olena
- Phillips Lawrence
- Pichette Vincent
- Pikalova Natalia
- Pilmore Helen
- Pintilei Ella
- Pistrosch Frank
- Pollock Carol
- Pontoriero Giuseppe
- Popenda Grazyna
- Povlsen Johan
- Powell Thomas
- Praga Terente Manuel
- Prager Rudolf
- Prieto Velasco Mario
- Prompt Carlos Alberto
- Pugliese Giuseppe
- Punt Zelda
- Quesada-Suarez Luis
- Rabbat Christian
- Rabindranath Kannaiyan
- Ramlachan Padaruth
- Ramos Aura
- Rampino Teresa
- Raslova Katarina
- Rassi Nelson
- Rastogi Anjay
- Ravera Maura
- Rechkova Elena
- Reichel Ronald
- Reisin Efrain
- Rendell Marc
- Renoirte Lopez Karina
- Rico Hernandez Raul
- Riella Miguel Carlos
- Robey Brooks
- Rodriguez-Perez Jose
- Roger Simon
- Rombola Giuseppe
- Ropero-Cartier Armando
- Rosado Carlos
- Rosenberger Jaroslav
- Rossing Peter
- Roy Louise
- Ruggenenti Piero
- Russo Domenico
- Rychlik Ivan
- Saba Fadi
- Sakai Takashi
- Sakhrani Lakhi
- Salles Joao
- Samoylova Yulia
- Santamaria Olmo Rafael
- Santoro Domenico
- Santos Canani Luis
- Santos Juan
- Sari Ramazan
- Sasaki Hiromitsu
- Sasaki Nobuhiro
- Satman Ilhan
- Sato Nobuyuki
- Sato Toshiaki
- Sato Yuichi
- Sauque Reyna Leobardo
- Savin Virginia
- Sayfutdinov Rustam
- Schenkenberger Isabelle
- Schmidt Alice
- Schmidt Rebecca
- Schmidt-Guertler Hans
- Scott David
- Segiet Thomas
- Sekikawa Takashi
- Sensenbrenner John
- Seo Ji A
- Seron Daniel
- Sezer Siren
- Shahid Newman
- Shamkhalova Minara
- Shaw Sylvia
- Sheu Wayne
- Shi Bingyin
- Shi Wei
- Shibagaki Yugo
- Shin Mijung
- Shinoda Junji
- Shon Ho Sang
- Shvarts Yuri
- Siamopoulos Konstantinos
- Sigitova Olga
- Simon Eric
- Skokowska Ewa
- Sligh Teresa
- Sloan Lance
- Slover Judith
- Smak Gregoor Peter
- Smolko Peter
- Smolyarchuk Elena
- Solomon Richard
- Solovev Oleg
- Soto Gonzalez Alfonso
- Sreenan Seamus
- Stack Austin
- Stanislavchuk Mykola
- Stefanidis Ioannis
- Stoica George
- Strand Jorma
- Stranks Stephen
- Stryzhak Vasyl
- Su Benli
- Suh Sung Hwan
- Sukor Norlela
- Sun Shiren
- Suranyi Michael
- Suzuki Katsunori
- Szerlip Harold
- Tadika Takenobu
- Takeda Tetsuro
- Taliercio John
- Tam Paul
- Tan Kathryn
- Tanaka Tsuyoshi
- Tanaka Yukio
- Tang Sydney
- Tarkan Joshua
- Taya Noriyasu
- Tentolouris Nikolaos
- Teo Boon Wee
- Tesar Vladimir
- Thakar Charuhas
- Thomson Stephen
- Tien Kai-Jen
- Tietjen David
- Timar Romulus
- Tindall Hilary
- Tkac Ivan
- Tkach Sergii
- Tobe Sheldon
- Tobe Sheldon
- Tokui Mikiya
- Tomilina Natalia
- Topchii Ivan
- Toussaint Nigel
- Trokis Julien
- Tseng Shih-Ting
- Tsuchida Kenichi
- Tsujimoto Tetsuro
- Tsutsui Masahiro
- Tulloch Brian
- Tuta Liliana
- Tutescu Adriana
- Ueda Shinichiro
- Ujihara Makoto
- Umayahara Yutaka
- Urena Torres Pablo
- Vaithilingam Indralingam
- Valera Cortes Ildefonso
- Vallejos Augusto
- Van Vlem Bruno
- Van Zyl Louis
- Vargas-Gonzales Rolando
- Varghese Freemu
- Vazquez-Tanus Jose
- Vengadasalam V Paranthaman P
- Vercammen Chris
- Vicks Steven
- Vielhauer Volker
- Vijayasingham Shalini
- Villevalde Svetlana
- Vogel Daniel
- Vogt Liffert
- Wainstein Julio
- Wang Song
- Wanner Christoph
- Warling Xavier
- Watanabe Shuichi
- Weinstein Debra
- Weinstein Talia
- Weiss Robert
- Weng Jian
- Whaley-Connell Adam
- Wiecek Andrzej
- Wigderson Melissa
- Wise Jonathan
- Wong Hin Seng
- Woo Jeong-Taek
- Wruk Michal
- Wu Du-An
- Wu Mai-Szu
- Xiao Guanqing
- Xing Changying
- Xu Gang
- Xu Yan
- Yagil Yoram
- Yalcin Murat
- Yamada Daishiro
- Yamaguchi Yukinari
- Yamamoto Masahiro
- Yamauchi Akira
- Yambe Yuko
- Yang Jinkui
- Yavdosyuk Andrey
- Yeoh Lee Ying
- Yeung Vincent
- Yi Joo Hark
- Yi Tingting
- Yildiz Alaattin
- Yoo Soon-Jib
- Yoon Kun Ho
- Yoon Sun Ae
- Youmbissi Joseph
- Yu Shengqiang
- Yu Tae Yang
- Zahumensky Emil
- Zanella Maria
- Zaoui Philippe
- Zapata-Rincon Luis
- Zea-Nunez Carlos Antonio
- Zeig Steven
- Zhao Hongwen
- Zhao Jiajun
- Zhao Minghui
- Zieve Franklin
- Zolotaikina Viktoriia
- Zrazhevskiy Konstantin
- Zucchini Alfredo
- Zuo Li
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background: Short-term treatment for people with type 2 diabetes using a low dose of the selective endothelin A receptor antagonist atrasentan reduces albuminuria without causing significant sodium retention. We report the long-term effects of treatment with atrasentan on major renal outcomes. Methods: We did this double-blind, randomised, placebo-controlled trial at 689 sites in 41 countries. We enrolled adults aged 18–85 years with type 2 diabetes, estimated glomerular filtration rate (eGFR)25–75 mL/min per 1·73 m 2 of body surface area, and a urine albumin-to-creatinine ratio (UACR)of 300–5000 mg/g who had received maximum labelled or tolerated renin–angiotensin system inhibition for at least 4 weeks. Participants were given atrasentan 0·75 mg orally daily during an enrichment period before random group assignment. Those with a UACR decrease of at least 30% with no substantial fluid retention during the enrichment period (responders)were included in the double-blind treatment period. Responders were randomly assigned to receive either atrasentan 0·75 mg orally daily or placebo. All patients and investigators were masked to treatment assignment. The primary endpoint was a composite of doubling of serum creatinine (sustained for ≥30 days)or end-stage kidney disease (eGFR <15 mL/min per 1·73 m 2 sustained for ≥90 days, chronic dialysis for ≥90 days, kidney transplantation, or death from kidney failure)in the intention-to-treat population of all responders. Safety was assessed in all patients who received at least one dose of their assigned study treatment. The study is registered with ClinicalTrials.gov, number NCT01858532. Findings: Between May 17, 2013, and July 13, 2017, 11 087 patients were screened; 5117 entered the enrichment period, and 4711 completed the enrichment period. Of these, 2648 patients were responders and were randomly assigned to the atrasentan group (n=1325)or placebo group (n=1323). Median follow-up was 2·2 years (IQR 1·4–2·9). 79 (6·0%)of 1325 patients in the atrasentan group and 105 (7·9%)of 1323 in the placebo group had a primary composite renal endpoint event (hazard ratio [HR]0·65 [95% CI 0·49–0·88]; p=0·0047). Fluid retention and anaemia adverse events, which have been previously attributed to endothelin receptor antagonists, were more frequent in the atrasentan group than in the placebo group. Hospital admission for heart failure occurred in 47 (3·5%)of 1325 patients in the atrasentan group and 34 (2·6%)of 1323 patients in the placebo group (HR 1·33 [95% CI 0·85–2·07]; p=0·208). 58 (4·4%)patients in the atrasentan group and 52 (3·9%)in the placebo group died (HR 1·09 [95% CI 0·75–1·59]; p=0·65). Interpretation: Atrasentan reduced the risk of renal events in patients with diabetes and chronic kidney disease who were selected to optimise efficacy and safety. These data support a potential role for selective endothelin receptor antagonists in protecting renal function in patients with type 2 diabetes at high risk of developing end-stage kidney disease. Funding: AbbVie
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5th International Symposium on Focused Ultrasound: North Bethesda, MD, USA. 28 August- 1 September 2016
- Author
- Abounader Roger
- Abraham Christopher
- Acosta Camilo
- Adams Matthew
- Adema Gosse
- Agrawal Punit
- Airan Raag
- Aleman Dionne
- Alexander Phillip
- Alkins Ryan
- Allen Steven
- Almquist Scott
- Alnazeer Moez
- Altman Michael
- Aly Amirah
- Amaral Joao Guilherme
- Amrahli Maral
- Amraoui Sana
- Andarawewa Kumari
- Andriyakhina Yulia
- Angstadt Mary
- Ankou Bénédicte
- Arias Ana Clauda
- Arvanitis Costas
- Aryal Muna
- Asadnia Kiana
- Aubert Isabelle
- Aubry Jean Francois
- Aubry Jean-Francois
- Aurup Christian
- Bader Kenneth
- Badr Lena
- Baek Hongchae
- Bailey Michael
- Barbato Gaetano
- Bartels Lambertus W.
- Bazzocchi Alberto
- Beccaria Kevin
- Bellorofonte Carlo
- Benson Lee
- Bernus Olivier
- Berriet Rémi
- Bertolina Jim
- Beskin Viktoriya
- Bessière Francis
- Bethune Allison
- Bezzi Mario
- Bing Chenchen
- Bitton Rachelle
- Bond Aaron
- Bonomo Guido
- Borowsky Alexander
- Borys Nicolas
- Bos Clemens
- Bouley Donna
- Bour Pierre
- Bourekas Eric
- Braat Manon
- Brenin David
- Bresler Michele
- Brokman Omer
- Brosh Inbar
- Buckner Andrew
- Bucknor Matthew
- Bullock Timothy
- Burks Scott
- Böttcher Joachim
- Cafarelli Andrea
- Cahill Jessica
- Cain Charles
- Camarena Francisco
- Camelo-Piragua Sandra
- Campbell Benjamin
- Campbell Fiona
- Cannata Jon
- Canney Michael
- Carlson Roy
- Carneiro Antonio
- Carpentier Alexandre
- Caskey Charles
- Catheline Stefan
- Cavin Ian
- Celik Haydar
- Centelles Miguell
- Cesana Claudio
- Chabok Hamid Reza
- Chamanara Marzieh
- Chang Jin Ho
- Chang Jin Woo
- Chang Won Seok
- Changizi Barbara
- Chapelon Jean Yves
- Chaplin Vandiver
- Chapman Martin
- Chaudhary Neeraj
- Chaussy Christian
- Chen Cherry
- Chen Hong
- Chen Johnny
- Chen Lili
- Chen Tung-Ho
- Chen Wohsing
- Chen Xiaoming
- Chevalier Philippe
- Chiou George
- Chiou Jeng-Fong
- Chisholm Alexander
- Chopra Rajiv
- Christensen Douglas
- Christofferson Ivy
- Chung Hyun Hoon
- Chung Yong An
- Ciuti Gastone
- Clement Gregory
- Colas Elodie Constanciel
- Cooper Mark
- Corea Joseph
- Corso Cristiano
- Cosman Josh
- Coughlin Dezba
- Crake Calum
- Cunitz Bryan
- Curiel Laura
- Curley Colleen
- Cvetkovic Dusica
- Czarnota Gregory
- Dababou Susan
- Dallapiazza Robert
- de Bever Joshua
- de Greef Martijn
- de Jager Bram
- de Ruiter Joost
- de Senneville Baudouin Denis
- Deckers Roel
- Delattre Jean-Yves
- Demedts Daniel
- den Brok Martijn
- Dhanaliwala Ali
- Diederich Chris
- Dillon Christopher
- Diodato Alessandro
- Dixon Adam
- Donner Elizabeth
- Downs Matthew
- Drake James
- Du Zhongmin
- Dubois Rémi
- Dupre Aurelien
- Eames Matt
- Eikelenboom Dylan
- Elias W. Jeff
- Ellens Nicholas
- Endre Ruby
- Eran Ayelet
- Eranki Avinash
- Erasmus Hans-Peter
- Evans Harrison
- Everstine Ashli
- Farahani Keyvan
- Farr Navid
- Farrer Alexis
- Farry Justin
- Federau Christian
- Feng Xue
- Ferrara Katherine
- Ferrer Cyril
- Ferrera Vincent
- Fielden Samuel
- Fishman Paul
- Fite Brett
- Foiret Josquin
- Foley Jessica
- Frank Joseph
- Frenkel Victor
- Fütterer Jurgen
- Gach H. Michael
- Gandhi Dheeraj
- Gedroyc Wladyslaw
- Gertner Michael
- Ghanouni Pejman
- Goldsher Dorit
- Gorgone Alessandro
- Greillier Paul
- Griesenauer Rebekah
- Grissom William
- Grondin Julien
- Grüll Holger
- Guenther Matthias
- Guha Chandan
- Gulati Amitabh
- Gullapalli Rao
- Guo Sijia
- Gupta Roohi
- Gupta Samit
- Gurm Hitinder
- Gwinn Ryder
- Götz Jürgen
- Güllmar Daniel
- Haase Sabrina
- Hadley Rock
- Hall Timothy
- Halpern Casey
- Hammoud Dima
- Han Yang
- Hananel Arik
- Hanes Justin
- Hargrove Amelia
- Hatch Robert
- Haworth Kevin
- Hazan Eilon
- Haïssaguerre Michel
- He Ye
- Heemels Maurice
- Heerschap Arend
- Heijman Edwin
- Hilas Elaine
- Hoang-Xuan Khe
- Hocini Mélèze
- Hodaie Mojgan
- Hofmann Denis
- Holland Christy
- Hoogenboom Martijn
- Hopyan Sevan
- Hossack John
- Houdouin Alexandre
- Hsu Fang-Chi
- Hsu Po-Hung
- Hu Jim
- Huang Yuexi
- Hurwitz Mark
- Huss Diane
- Hwang Chang-il
- Hwang Joo Ha
- Hynynen Kullervo
- Idbaih Ahmed
- Ikeuchi Masahiko
- Ingham Elizabeth
- Ives Kimberly
- Izumi Masashi
- Jackson-Lewis Vernice
- Jang Kee W.
- Janát-Amsbury Margit
- Jedruszczuk Kathleen
- Jeng Shiu-Chen
- Jenne Jürgen
- Jikaria Neekita
- Jiménez Noé
- Jiménez-Gambín Sergio
- Jin Changzhu
- Johnson Sara
- Jonathan Sumeeth
- Jones Peter
- Joy Joyce
- Jung Hyun Ho
- Jung Na Young
- Jung Yujin
- Kahn Itamar
- Kamimura Hermes
- Kamrava Seyed Kamran
- Kang Jeeun
- Kang Kook Jin
- Kang Soo Yeon
- Kao Yi-tzu
- Karakatsani Maria Eleni (Marilena)
- Karakitsios Ioannis
- Kassell Neal
- Katti Prateek
- Kawasaki Motohiro
- Kaye Elena
- Keupp Jochen
- Kheirolomoom Azadeh
- Khokhlova Tatiana
- Khokhlova Vera
- Kim AeRang
- Kim Harry
- Kim Hyun-Chul
- Kim Hyuncheol
- Kim Hyungmin
- Kim Min Soo
- Kim Namho
- Kim Peter
- Kim Saejeong
- Kim Young-sun
- Kimmel Eitan
- Kiyasu Katsuhito
- Klibanov Alexander
- Kneepkens Esther
- Knopp Michael
- Kobus Thiele
- Konofagou Elisa
- Koral Korgun
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- Kovacs Zsofia
- Kovatcheva Roussanka
- Kreider Wayne
- Krishna Vibhor
- Krug Roland
- Krupa Steve
- Kugelman Tara
- Kuo Chia-Chun
- Kwiecinski Wojciech
- Lacoste Romain
- Laetsch Theodore
- Lafon Cyril
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- Lamberti-Pasculli Maria
- Lang Brian
- Langø Thomas
- Larner James
- Larrabee Zachary
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- Leclercq Delphine
- Lee Hak Jong
- Lee Hsin-Lun
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- Magat Julie
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- Maimon Noam
- Mainprize Todd
- Malayer Jerry
- Maples Danny
- Marquet Fabrice
- Marrocchio Cristina
- Marx Mike
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- Mauri Giovanni
- Maxwell Adam
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- McLean Hailey
- McLeod Helen
- McMichael John
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- Melodelima David
- Melot-Dusseau Sandrine
- Melzer Andreas
- Menciassi Arianna
- Merrill Robb
- Meyer Craig
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- Miga Michael
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- Mihcin Senay
- Miller Eric
- Miller Wilson
- Milo Blerta
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- Moon Hyungwon
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- Mourad Pierre
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- Mueller Michael
- Mugler John
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- Nagle Matthew
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- Nguyen Ben
- Nguyen Thai-Son
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- Nisbet Rebecca
- Nofiele Joris
- Odéen Henrik
- Oetgen Matthew
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- Olumolade Oluyemi
- Orsi Franco
- Owens Gabe
- Ozhinsky Eugene
- Ozilgen Arda
- Padegimas Linas
- Paeng Dong-Guk
- Palermo Carmine
- Pan Chia-Hsin
- Pandey Aditya
- Papadakis Georgios
- Papademetriou Iason T.
- Park Chang Kyu
- Park Sang Man
- Parker Dennis
- Parker Jonathon
- Partanen Ari
- Parvizi Mohammad Hossein
- Pascal-Tenorio Aurea
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- Rothluebbers Sven
- Ruiz Antonio
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- Sasaki Noboru
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- Sat Giora
- Schade George
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- Skalina Karin
- Slingluff Craig
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- Solomon Stephen
- Sommer Graham
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- Song In-Uk
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- Thanou Maya
- Thueroff Stefan
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- Tognarelli Selene
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- Trudeau Maureen
- Tsai Yi-Chieh
- Tsysar Sergey A.
- Tu Tsang-Wei
- Tucci Samantha
- Tuveson David
- Ushida Takahiro
- Vaessen Paul
- Vaillant Fanny
- Van Arsdell Glen
- van Breugel Johanna
- van den Bosch Maurice
- Van der Jeugd Ann
- Van der Jeugd Anneke
- Van der Wall Elsken
- van Diest Paul
- van Stralen Marijn
- Varano Gianluca
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- Vidal-Jove Joan
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- Vignot Alexandre
- Vincenot Jeremy
- Vlahov Jordan
- Vykhodtseva Natalia
- Wang Bin
- Wang Han
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- Wang Qi
- Wang Qingguo
- Wang Shengping
- Wang Shutao
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- Wang Zhaorui
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- Watson Katherine
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- Wei Kuo-Chen
- Wei-Bin Shen
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- Weissler Yoni
- Werner Beat
- Wesseling Pieter
- Williams Noelle
- Wilson Emmanuel
- Wintermark Max
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- Wydra Adrian
- Xiao Xu
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- Xu Doudou
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- Xu Zhiyuan
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- Yao Chen
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- Yarowsky Paul
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- Yoo Seung-Schik
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- Zhang Hua
- Zhang Jimin
- Zhang Junhai
- Zhang Xi
- Zhang Ying
- Zhang Yong-Zhi
- Zhao Li
- Zhong Pei
- Zhuo Jiachen
- Zidowitz Stephan
- Zinke Wolf
- Zorgani Ali
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 03/01/2017
- Field of study
Contributors
- Author
- Aalen Reidunn B.
- Abdel-Wahab Yasser H.A.
- Adams Michael E.
- Adan Roger A.H.
- Ahima Rexford S.
- Ahmed Naima
- Al-Massadi Omar
- Altstein Miriam
- Anouar Youssef
- Anselmi Laura
- Ansorge Siegfried
- Antcheva Nikolinka
- Antonova-Koch Yevgeniya
- Appel Jon R.
- Arik Anam J.
- Arter Alison L.
- Arvan Peter
- Ashkenazi Avraham
- Baas P.W.
- Bado André
- Baird Andrew
- Baiula Monica
- Bakaletz Lauren O.
- Bakken Earl E.
- Balaskó Márta
- Baldwin Graham S.
- Banks William A.
- Barra Donatella
- Barson Jessica R.
- Basille Magali
- Bauer Natalie N.
- Bedini Andrea
- Beeton Christine
- Begley David J.
- Beinfeld Margery C.
- Bendena William G.
- Benoit Stephen C.
- Bentov Itay
- Bern Howard
- Bierbaum Gabriele
- Billington Charles J.
- Blasiak Anna
- Block Norman L.
- Bloom Stephen. R.
- Bolette Hartmann Carolyn F. Deacon
- Bonney Iwona
- Bowie John H.
- Boyd Sunny K.
- Brain Susan D.
- Brede Dag A.
- Broeck Jozef Vanden
- Brown Kelly L.
- Brown Mark R.
- Bugni James M.
- Bundgaard Jens R.
- Burel Delphine
- Butenko Melinka A.
- Call Melissa J.
- Calò Girolamo
- Campbell Duncan John
- Carlsson Anna
- Carr Daniel B.
- Carraway Robert E.
- Carreira Marcos C.
- Casanueva Felipe F.
- Cassella Sarah N.
- Casson Stuart A.
- Castaño Justo P.
- Cebrat Marek
- Chappe Valerie
- Chatenet David
- Chen Chen
- Chen Duan
- Chen Keqiang
- Chen Longchuan
- Cheng Carrie Y.Y.
- Chi-Jen Lin James
- Cho Sung Ki
- Chow Billy K.C.
- Christopoulos Arthur
- Chu Shijian
- Clarke Iain J.
- Coast Geoffrey M.
- Compere Vincent
- Concepcion Gisela P.
- Cone Roger D.
- Conlon J. Michael
- Cornélissen Germaine
- Courel Maité
- Couture Réjean
- Cramer W.A.
- Croft Nathan P.
- Crujeiras Ana B.
- Cuttitta Frank
- Cynis Holger
- D'Acquisto F.
- David Xu Zhi-Qing
- Davis Jon F.
- Davis Thomas P.
- de la Fuente-Núñez César
- de La Serre Claire Barbier
- de la Vega Ricardo C. Rodríguez
- de Lartigue Guillaume
- de Lecea Luis
- de Oliveira Santos Marcelo
- De Waard Michel
- Delestre Charlène
- Delgado Mario
- Demuth Hans-Ulrich
- Deng Xiaoming
- Dharmawardhana Palitha
- Di Cosmo Anna
- Dias Simoni Campos
- Dickerson Jonathan W.
- Diep Dzung B.
- Dircksen H.
- Dischinger Jasmin
- do Rego Jean-Claude
- Dobner Paul R.
- Dockray Graham J.
- Dores Robert M.
- Ducroc Robert
- Dudek Nadine L.
- Dumont Yvan
- Duraffourd Celine
- Duterte-Boucher Dominique
- Eberlé Alex N.
- Egleton Richard D.
- Eipper Betty A.
- Engel Jorg B.
- Englander Ella W.
- Epelbaum Jacques
- Erlanson-Albertsson Charlotte
- Eugene Pekary A.
- Evangelista S.
- Fagan Karen A.
- Farber Joshua M.
- Farkasfalvi Klára
- Fekete Csaba
- Flatt Peter R.
- Flower R.J.
- Forssmann Wolf-Georg
- Fournier Alain
- Foy Kevin Chu
- Franco Octávio Luiz
- Frenkel Dan
- Fricker Lloyd D.
- Fukuda Hiroo
- Galas Ludovic
- Gallagher Patricia E.
- Gandolfo Pierrick
- Garcia-Espinosa Maria A.
- García-Sanmartín Josune
- Geary Nori
- Geng Hua
- Germano Patrizia M.
- Goetze Jens P.
- Gonzalez Alexis A.
- Gonzalez Ana
- Gosnell Blake A.
- Goto Katsutoshi
- Gourcerol Guillaume
- Gozes I.
- Gracia-Navarro Francisco
- Grayson Bernadette E.
- Greeley George H.
- Greenwald-Yarnell Megan
- Gressens Pierre
- Grider John R.
- Grünewald Jan
- Guerreiro Juliano R.
- Guerrini Remo
- Guida Filomena
- Guilhaudis Laure
- Guilmeau Sandra
- Gundlach Andrew L.
- Gutkowska Jolanta
- Gäde Gerd
- Hackbarth Clifton
- Haim Ohana Y.
- Halberg Franz
- Hallberg Mathias
- Hamidi Sayyed A.
- Han Ji-Sheng
- Han Song
- Hancock Robert E.W.
- Haque Samer-ul
- Hara-Nishimura Ikuko
- Hariton Aliza
- Hartsock Wendy J.
- Harvey Alan L.
- Hasunuma Itaru
- Henning Robert J.
- Heppner Kristy M.
- Hertweck Kate L.
- Herzog Herbert
- Higashiyama Tetsuya
- Hinuma Shuji
- Hippenstiel Stefan
- Hirakawa Yuki
- Hirose Shuichi
- Hirsch Jochen R.
- Hocke Andreas C.
- Hodges Robert S.
- Hoffmann Werner
- Holst Jens Juul
- Holzer Peter
- Horodyski Frank M.
- Hosoda Hiroshi
- Hou Xiaowen
- Huffaker Alisa
- Hökfelt Tomas
- Iijima Norio
- Ikeuchi Momoko
- Imperial Julita S.
- Improta Giovanna
- Inui Akio
- Irwin Nigel
- Ishii Munehiro
- Iturrioz Xavier
- Ivanisevic Ljubica
- Iwao Hiroshi
- Iwata Takeo
- Izumi Yasukatsu
- Izumiyama Hajime
- Jankowski Marek
- Janssen Tom
- Jensen Robert T.
- Jethwa Preeti H.
- Johannessen Helene
- Johanson Conrad
- Judkowski Valeria
- Jégou Sylvie
- Kaczmarek Przemyslaw
- Kageyama Haruaki
- Kakimoto Tatsuo
- Kang Ki Sung
- Kangawa Kenji
- Kastin Abba J.
- Kato Johji
- Kaumaya Pravin T.P.
- Keep Richard F.
- Kem William R.
- Khomenko Tetyana
- Kikuyama Sakae
- Kim Young-Joon
- Kimura Sadao
- King Ross
- Kiptoo Paul
- Kishimoto Ichiro
- Kitamura Kazuo
- Kluczyk Alicja
- Kobori Hiroyuki
- Kodama Yosuke
- Kojima Masayasu
- Kondo Yuki
- Kosson Piotr
- Kotz Catherine M.
- Krishnan Bhavani
- Kulseng Bård
- Kumpf Robert
- Körner Meike
- Laburthe Marc
- Lacaille Hélène
- Ladenheim Ellen E.
- Ladram Ali
- Laksitorini Marlyn D.
- Lambert David G.
- Lange Angela B.
- Langhans Wolfgang
- Larauche Muriel
- Larhammar Dan
- Larráyoz Ignacio M.
- Lattanzi Roberta
- Lechan Ronald M.
- Lefranc Benjamin
- Leibowitz Sarah F.
- Lelièvre Vincent
- Leprince Jérôme
- Levine Allen S.
- Li Qun
- Lifshitz Veronica
- Lihrmann Isabelle
- Lindberg Iris
- Lindsey Keith
- Lipkowski Andrzej W.
- Liron T.
- Liu Junli
- Liu Min
- Liu Ying
- Llorens-Cortes Catherine
- Loizidou Marilena
- Lopez C.
- Lovejoy David A.
- Luca Vincenzo
- Lutz Thomas A.
- Ma Sherie
- Mains Richard E.
- Malagon Maria M.
- Malendowicz Ludwik K.
- Mangoni Maria Luisa
- Manigrasso Michaele B
- Marahiel Mohamed A.
- Marco Heather G.
- Maric-Bilkan Christine
- Marks Nikki J.
- Martin Roland
- Martinez Vicente
- Martinez-Fuentes Antonio J.
- Martínez Alfredo
- Masler Edward P.
- Matsubayashi Yoshikatsu
- Mattu Harman S.
- Maule Aaron G.
- McLaughlin Patricia J.
- McMurtry Ivan F.
- Meelkop Ellen
- Mehdi Saher
- Melchiorri Pietro
- Millar R.P.
- Miller Laurence J.
- Miller Miles
- Million Mulugeta
- Minamino Naoto
- Mittelman M.
- Miyauchi Takashi
- Miyazato Mikiya
- Mizoguchi Hirokazu
- Mohme Malte
- Montero-Hadjadje Maité
- Moody Terry W.
- Mookherjee Neeloffer
- Moran Timothy H.
- Morganstern Irene
- Mori Masatomo
- Morin Fabrice
- Morris John F.
- Moura Daniel S.
- Mudge Anna J.
- Mul Joram D.
- Murthy Karnam S.
- Myers Martin G.
- Nachman Ronald J.
- Nahon Jean-Louis
- Naithani Sushma
- Nakada Tomoaki
- Nakamachi Tomoya
- Nakamura Yuki
- Nalivaeva Natalia N.
- Nasrallah June B.
- Navar L. Gabriel
- Neelakantan Pratap
- Negri Lucia
- Nes Ingolf F.
- Neumann D.
- Neveu Cindy
- Ng Stephanie Y.L.
- Ng Tzi Bun
- Nicholson Graham M.
- Nicolas Pierre
- Nishikimi Toshio
- Nishiyama Mariko
- Nogueiras Rubén
- Norton Raymond S.
- Novotny Laura A.
- Nowak Krzysztof W.
- Nyberg Fred
- Nässel Dick R.
- Ochoa-Callejero Laura
- Oh-I Shinsuke
- Ohgusu Hideko
- Ojo Opeolu O.
- Olivera Baldomero M.
- Olucha-Bordonau Francisco E.
- Oppenheim Joost J.
- Orchard Ian
- Ouellette André J.
- Ove Ögren Sven
- Pacheco-López Gustavo
- Page Nigel M.
- Palma Mario Sergio
- Pan Weihong
- Park Yoonseong
- Parmentier Marc
- Passemard Sandrine
- Patterson Michael
- Paunovic Brankica
- Pearce Gregory
- Pedersen Jens
- Peeters Theo L.
- Pelletier Georges
- Perboni Simona
- Perjés Ábel
- Perretti M.
- Pinilla Clemencia
- Pinskim Jacek
- Pisegna Joseph R.
- Plankensteiner Kristof
- Podvin Sonia
- Poitras Pierre
- Polese Gianluca
- Pollock David M.
- Porto William Farias
- Possani Lourival D.
- Pothoulakis Charalabos
- Presse Françoise
- Prieto Minolfa C.
- Prutchi-Sagiv S.
- Purcell Anthony W.
- Purtell Louise
- Pérez-Tilve Diego
- Pétervári Erika
- Quirion Rémi
- Rabat Catalina Abad
- Rademaker Miriam
- Rajpal Gautam
- Randeva Harpal S.
- Rebuffat Sylvie
- Reeve Joseph R.
- Rehfeld Jens F.
- Reinhold Dirk
- Reinscheid Rainer K.
- Reubi Jean Claude
- Rezvani Katayoun
- Ribeiro Suzana Meira
- Richard D.
- Richards Mark
- Riehle Michael A.
- Rinaldi Andrea C.
- Rode Bernd M.
- Rotzinger Susan
- Rucinski Marcin
- Ruskoaho Heikki
- Ryan Philip J.
- Sabatier Jean-Marc
- Sahl Hans-Georg
- Said Sami I.
- Sakurada Shinobu
- Sakurada Tsukasa
- Salomon David S.
- Samson Willis K.
- Sandor Zsuzsanna
- Saragovi H. Uri
- Sasaki Kazuki
- Sato Takahiro
- Satou Ryousuke
- Sawa Shinichiro
- Sayegh Ayman I.
- Schally Andrew V.
- Schilling Stephan
- Schoofs Liliane
- Schooley David A.
- Schubert Mitchell L.
- Segalas-Milazzo Isabelle
- Seidah Nabil G.
- Selsted Michael E.
- Seroogy Kim B.
- Severini Cinzia
- Sexton Patrick M.
- Shai Yechiel
- Sharma O.
- Shichiri Masayoshi
- Shimada Tomoo
- Shimizu Hiroyuki
- Shioda Seiji
- Shulkes Arthur
- Siahaan Teruna J.
- Siemion Ignacy Z.
- Silva Osmar Nascimento
- Silva-Filho Marcio C.
- Skwarczynski Mariusz
- Small Caroline. J.
- Smith A. Ian
- Smith Craig M.
- Smith David E.
- Solomon Beka
- Solomon Travis E.
- Sospedra Mireia
- Souroujon M.C.
- Spampinato Santi
- Spindel Eliot R.
- Steiger A.
- Stengel Andreas
- Sternini Catia
- Steyn Frederik J.
- Stopa Edward
- Strowski Mathias Z.
- Sugano Shigeo S.
- Sundström Görel
- Sutcliffe J. Gregor
- Suttorp Norbert
- Sweedler Jonathan V.
- Szabo Sandor
- Szokodi István
- Székely Miklós
- Taché Yvette
- Takahashi Kazuhiro
- Takei Yoshio
- Takenoya Fumiko
- Talbot Sébastien
- Tallant E. Ann
- Tan Tricia M.
- Temmerman Liesbet
- Temmesfeld-Wollbrück Bettina
- Tena-Sempere Manuel
- Thorsell Annika
- Tilakaratne Nanda
- Tobe Stephen S.
- Tokudome Takeshi
- Tolstanova Ganna
- Tonon Marie-Christine
- Topping Jennifer F.
- Tossi Alessandro
- Tostivint Hervé
- Toth Istvan
- Totsune Kazuhito
- Toyoda Fumiyo
- Troke Rachel
- Tschöp Matthias H.
- Tso Patrick
- Tsukaya Hirokazu
- Tsutsui Kazuyoshi
- Tu Hong
- Turner Anthony J.
- Ubuka Takayoshi
- Valdivia Elene R.
- Vandersmissen Hans Peter
- Vaudry David
- Vaudry Hubert
- Vazquez-Martinez Rafael
- Verbalis Joseph G.
- Vicari Daniele
- Vidal Nicolas
- Vignoni Marzia
- Viollet Cécile
- Vishwanatha K.S.
- Vivoli Mirella
- Voisin Thierry
- Vu John P.
- Walker John C.
- Wallace B.A.
- Wan Jennifer Man-Fan
- Wang Ji Ming
- Wang Lixin
- Wardman Jonathan H.
- Watanabe Takuya
- Welch Hazel
- Werner Haim
- Whitmore L.
- Wiedemann Imke
- Winsky-Sommerer Raphaelle
- Witt Ken A.
- Wojciechowicz Tatiana
- Wong Jack Ho
- Woods Stephen C.
- Wootten Denise
- Wu Vincent
- Wurtz Olivier
- Xiong Ximing
- Yamaguchi Takahiro
- Yamaguchi Yube
- Yamamoto Kazutoshi
- Yamashita E.
- Yamazaki Hiroyuki
- Yang De
- Yoshikawa Masaaki
- Yuan Pu-Qing
- Yung Sunny C.
- Zagon Ian S.
- Zakharov S.D.
- Zaman Mehfuz
- Zhalnina M.V.
- Zhang Ning
- Zhang-Auberson Lixin
- Zhao Chun-Mei
- Ziolkowska Agnieszka
- Zitnan Dusan
- Publication venue
- Elsevier
- Publication date
- 01/01/2013
- Field of study
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
- Author
- Abdelmohsen Kotb
- Abe Akihisa
- Abedin Md Joynal
- Abeliovich Hagai
- Adachi Hiroaki
- Adams Christopher M.
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- Wilkinson Simon
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- Xu Jianzhen
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- Xu Xiaolei
- Xu Yangqing
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- Xu Zhi-Xiang
- Xu Ziheng
- Xue Yu
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- Yamanaka Koji
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- Yamashiro Shigeko
- Yan Bing
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- Yedvobnick Barry
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- Yeh Elizabeth S.
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- Yi Fan
- Yi Long
- Yin Xiao-Ming
- Yip Calvin K.
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- Yoo Young Hyun
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- Yoshida Ken-Ichi
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- Yu Huixin
- Yu Jane J.
- Yu Jin-Tai
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- Yu W. Haung
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- Yue Zhenyu
- Zacks David N.
- Zacksenhaus Eldad
- Zaffaroni Nadia
- Zaglia Tania
- Zakeri Zahra
- Zecchini Vincent
- Zeng Jinsheng
- Zeng Min
- Zeng Qi
- Zervos Antonis S.
- Zhang Donna D.
- Zhang Fan
- Zhang Guo
- Zhang Guo-Chang
- Zhang Hao
- Zhang Hong
- Zhang Hongbing
- Zhang Jian
- Zhang Jiangwei
- Zhang Jianhua
- Zhang Jing-Pu
- Zhang Li
- Zhang Lin
- Zhang Long
- Zhang Ming-Yong
- Zhang Xiangnan
- Zhang Xu Dong
- Zhang Yan
- Zhang Yang
- Zhang Yanjin
- Zhang Yingmei
- Zhang Yunjiao
- Zhao Mei
- Zhao Wei-Li
- Zhao Xiaonan
- Zhao Yan G.
- Zhao Ying
- Zhao Yongchao
- Zhao Yu-Xia
- Zhao Zhendong
- Zhao Zhizhuang J.
- Zheng Dexian
- Zheng Xi-Long
- Zheng Xiaoxiang
- Zhivotovsky Boris
- Zhong Qing
- Zhou Guang-Zhou
- Zhou Guofei
- Zhou Huiping
- Zhou Shu-Feng
- Zhou Xu-Jie
- Zhu Hongxin
- Zhu Hua
- Zhu Wei-Guo
- Zhu Wenhua
- Zhu Xiao-Feng
- Zhu Yuhua
- Zhuang Shi-Mei
- Zhuang Xiaohong
- Ziparo Elio
- Zois Christos E.
- Zoladek Teresa
- Zong Wei-Xing
- Zorzano Antonio
- Zughaier Susu M.
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2016
- Field of study
non present
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- Author
- Abdelmohsen Kotb
- Abe Akihisa
- Abedin Md Joynal
- Abeliovich Hagai
- Adachi Hiroaki
- Adams Christopher M.
- Adams Peter D.
- Adeli Khosrow
- Adhihetty Peter J.
- Adler Sharon G.
- Agam Galila
- Agarwal Rajesh
- Aghi Manish K.
- Agnello Maria
- Agostinis Patrizia
- Aguilar Patricia V.
- Aguirre-Ghiso Julio
- Airoldi Edoardo M.
- Ait-Si-Ali Slimane
- Akematsu Takahiko
- Akporiaye Emmanuel T.
- Al-Rubeai Mohamed
- Albaiceta Guillermo M.
- Albanese Chris
- Albani Diego
- Albert Matthew L.
- Aldudo Jesus
- Alguel Hana
- Alirezaei Mehrdad
- Alloza Iraide
- Almasan Alexandru
- Almonte-Beceril Maylin
- Alnemri Emad S.
- Alonso Covadonga
- Altan-Bonnet Nihal
- Altieri Dario C.
- Alvarez Silvia
- Alvarez-Erviti Lydia
- Alves Sandro
- Amadoro Giuseppina
- Amano Atsuo
- Amantini Consuelo
- Ambrosio Santiago
- Amelio Ivano
- Amer Amal O.
- Amessou Mohamed
- Amon Angelika
- An Zhenyi
- Ana Gonzalez-Polo Rosa
- Anania Frank A.
- Andersen Stig U.
- Andley Usha P.
- Andreadi Catherine K.
- Andrieu-Abadie Nathalie
- Anel Alberto
- Ann David K.
- Anoopkumar-Dukie Shailendra
- Antonioli Manuela
- Aoki Hiroshi
- Apostolova Nadezda
- Aquila Saveria
- Aquilano Katia
- Araki Koichi
- Arama Eli
- Aranda Agustin
- Araya Jun
- Arcaro Alexandre
- Arias Esperanza
- Arimoto Hirokazu
- Ariosa Aileen R.
- Armstrong Jane L.
- Arnould Thierry
- Arozena Abraham Acevedo
- Arsov Ivica
- Asanuma Katsuhiko
- Askanas Valerie
- Asselin Eric
- Atarashi Ryuichiro
- Atherton Sally S.
- Atkin Julie D.
- Attardi Laura D.
- Auberger Patrick
- Auburger Georg
- Aurelian Laure
- Autelli Riccardo
- Avagliano Laura
- Avantaggiati Maria Laura
- Avrahami Limor
- Awale Suresh
- Azad Neelam
- Bachetti Tiziana
- Backer Jonathan M.
- Bae Dong-Hun
- Bae Jae-Sung
- Bae Ok-Nam
- Bae Soo Han
- Baehrecke Eric H.
- Baek Seung-Hoon
- Baghdiguian Stephen
- Bagniewska-Zadworna Agnieszka
- Bai Hua
- Bai Jie
- Bai Xue-Yuan
- Bailly Yannick
- Balaji Kithiganahalli Narayanaswamy
- Balduini Walter
- Ballabio Andrea
- Balzan Rena
- Banerjee Rajkumar
- Banhegyi Gabor
- Bao Haijun
- Barbato Daniele Lettieri
- Barbeau Benoit
- Barrachina Maria D.
- Barreiro Esther
- Bartel Bonnie
- Bartolome Alberto
- Bassham Diane C.
- Bassi Maria Teresa
- Bast Robert C., Jr.
- Basu Alakananda
- Batista Maria Teresa
- Batoko Henri
- Battino Maurizio
- Bauckman Kyle
- Baumgarner Bradley L.
- Bayer K. Ulrich
- Beale Rupert
- Beaulieu Jean-Francois
- Beck George R., Jr.
- Becker Christoph
- Beckham J. David
- Bedard Pierre-Andre
- Bednarski Patrick J.
- Begley Thomas J.
- Behl Christian
- Behrends Christian
- Behrens Georg M. N.
- Behrns Kevin E.
- Bejarano Eloy
- Belaid Amine
- Belleudi Francesca
- Benard Giovanni
- Berchem Guy
- Bergamaschi Daniele
- Bergami Matteo
- Berkhout Ben
- Berliocchi Laura
- Bernard Amelie
- Bernard Monique
- Bernassola Francesca
- Bertolotti Anne
- Bess Amanda S.
- Besteiro Sebastien
- Bettuzzi Saverio
- Bhalla Savita
- Bhattacharyya Shalmoli
- Bhutia Sujit K.
- Biagosch Caroline
- Bianchi Michele Wolfe
- Biard-Piechaczyk Martine
- Billes Viktor
- Bincoletto Claudia
- Bingol Baris
- Bird Sara W.
- Bitoun Marc
- Bjedov Ivana
- Blackstone Craig
- Blanc Lionel
- Blanco Guillermo A.
- Blomhoff Heidi Kiil
- Boada-Romero Emilio
- Boeckler Stefan
- Boes Marianne
- Boesze-Battaglia Kathleen
- Boise Lawrence H.
- Bolino Alessandra
- Boman Andrea
- Bonaldo Paolo
- Bordi Matteo
- Bosch Jurgen
- Botana Luis M.
- Botti Joelle
- Bou German
- Bouche Marina
- Bouchecareilh Marion
- Boucher Marie-Josee
- Boulton Michael E.
- Bouret Sebastien G.
- Boya Patricia
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- Bozhkov Peter V.
- Brady Nathan
- Braga Vania M. M.
- Brancolini Claudio
- Braus Gerhard H.
- Bravo-San Pedro Jose M.
- Brennan Lisa A.
- Bresnick Emery H.
- Bressan Queiroz de Figueiredo Regina Celia
- Brest Patrick
- Bridges Dave
- Bringer Marie-Agnes
- Brini Marisa
- Brito Glauber C.
- Brodin Bertha
- Brookes Paul S.
- Brown Eric J.
- Brown Karen
- Broxmeyer Hal E.
- Bruhat Alain
- Brum Patricia Chakur
- Brumell John H.
- Brunetti-Pierri Nicola
- Bryson-Richardson Robert J.
- Buch Shilpa
- Buchan Alastair M.
- Budak Hikmet
- Buetikofer Peter
- Bulavin Dmitry V.
- Bultman Scott J.
- Bultynck Geert
- Bumbasirevic Vladimir
- Burelle Yan
- Burke Robert E.
- Burmeister Margit
- Caberlotto Laura
- Cadwell Ken
- Cahova Monika
- Cai Dongsheng
- Cai Jingjing
- Cai Qian
- Calatayud Sara
- Camougrand Nadine
- Campanella Michelangelo
- Campbell Grant R.
- Campbell Matthew
- Campello Silvia
- Candau Robin
- Caniggia Isabella
- Cantoni Lavinia
- Cao Lizhi
- Caplan Allan B.
- Caraglia Michele
- Cardinali Claudio
- Cardoso Sandra Morais
- Carew Jennifer S.
- Carleton Laura A.
- Carlin Cathleen R.
- Carloni Silvia
- Carlsson Sven R.
- Carmona-Gutierrez Didac
- Carneiro Leticia A. M.
- Carnevali Oliana
- Carra Serena
- Carrier Alice
- Carroll Bernadette
- Casas Caty
- Casas Josefina
- Cassinelli Giuliana
- Castets Perrine
- Castro-Obregon Susana
- Cavallini Gabriella
- Ceccherini Isabella
- Cecconi Francesco
- Cederbaum Arthur I.
- Cena Valentin
- Cenci Simone
- Cerella Claudia
- Cervia Davide
- Cetrullo Silvia
- Chaachouay Hassan
- Chae Han-Jung
- Chagin Andrei S.
- Chai Chee-Yin
- Chakrabarti Gopal
- Chamilos Georgios
- Chan Edmond Y. W.
- Chan Matthew T. V.
- Chandra Dhyan
- Chandra Pallavi
- Chang Chih-Peng
- Chang Raymond Chuen-Chung
- Chang Ta Yuan
- Chatham John C.
- Chatterjee Saurabh
- Chauhan Santosh
- Che Yongsheng
- Cheetham Michael E.
- Cheluvappa Rajkumar
- Chen Chun-Jung
- Chen Gang
- Chen Guang-Chao
- Chen Guoqiang
- Chen Hongzhuan
- Chen Jeff W.
- Chen Jian-Kang
- Chen Min
- Chen Mingzhou
- Chen Peiwen
- Chen Qi
- Chen Quan
- Chen Shang-Der
- Chen Si
- Chen Steve S-L
- Chen Wei
- Chen Wei-Jung
- Chen Wen Qiang
- Chen Wenli
- Chen Xiangmei
- Chen Yau-Hung
- Chen Ye-Guang
- Chen Yin
- Chen Yingyu
- Chen Yongshun
- Chen Yu-Jen
- Chen Yue-Qin
- Chen Yujie
- Chen Zhen
- Chen Zhong
- Cheng Alan
- Cheng Christopher H. K.
- Cheng Hua
- Cheong Heesun
- Cherry Sara
- Chesney Jason
- Cheung Chun Hei Antonio
- Chevet Eric
- Chi Hsiang Cheng
- Chi Sung-Gil
- Chiacchiera Fulvio
- Chiang Hui-Ling
- Chiarelli Roberto
- Chiariello Mario
- Chieppa Marcello
- Chin Lih-Shen
- Chiong Mario
- Chiu Gigi N. C.
- Cho Dong-Hyung
- Cho Ssang-Goo
- Cho William C.
- Cho Yong-Yeon
- Cho Young-Seok
- Choi Augustine M. K.
- Choi Eui-Ju
- Choi Eun-Kyoung
- Choi Jayoung
- Choi Mary E.
- Choi Seung-Il
- Chou Tsui-Fen
- Chouaib Salem
- Choubey Divaker
- Choubey Vinay
- Chow Kuan-Chih
- Chowdhury Kamal
- Chu Charleen T.
- Chuang Tsung-Hsien
- Chun Taehoon
- Chung Hyewon
- Chung Taijoon
- Chung Yuen-Li
- Chwae Yong-Joon
- Cianfanelli Valentina
- Ciarcia Roberto
- Ciechomska Iwona A.
- Ciriolo Maria Rosa
- Cirone Mara
- Claerhout Sofie
- Clague Michael J.
- Claria Joan
- Clarke Peter G. H.
- Clarke Robert
- Clementi Emilio
- Cleyrat Cedric
- Cnop Miriam
- Coccia Eliana M.
- Cocco Tiziana
- Codogno Patrice
- Coers Joern
- Cohen Ezra E. W.
- Colecchia David
- Coletto Luisa
- Coll Nuria S.
- Colucci-Guyon Emma
- Comincini Sergio
- Condello Maria
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- Corasaniti Maria Tiziana
- Corazzari Marco
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- Cordero Mario D.
- Corral-Ramos Cristina
- Corti Olga
- Cossarizza Andrea
- Costelli Paola
- Costes Safia
- Costes Safia
- Coto-Montes Ana
- Cottet Sandra
- Couve Eduardo
- Covey Lori R.
- Cowart L. Ashley
- Cox Jeffery S.
- Coxon Fraser P.
- Coyne Carolyn B.
- Cragg Mark S.
- Craven Rolf J.
- Crepaldi Tiziana
- Crespo Jose L.
- Criollo Alfredo
- Crippa Valeria
- Cruz Maria Teresa
- Cuervo Ana Maria
- Cuezva Jose M.
- Cui Taixing
- Cutillas Pedro R.
- Czaja Mark J.
- Czyzyk-Krzeska Maria F.
- D'Amelio Marcello
- D'Orazi Gabriella
- Dagda Ruben K.
- Dahmen Uta
- Dai Chunsun
- Dai Wenjie
- Dai Yun
- Dalby Kevin N.
- Dalmasso Guillaume
- Damme Markus
- Darfeuille-Michaud Arlette
- Dargemont Catherine
- Darley-Usmar Victor M.
- Dasarathy Srinivasan
- Dasgupta Biplab
- Dash Srikanta
- Dass Crispin R.
- Davey Hazel Marie
- Davids Lester M.
- Davila David
- Davis Roger J.
- Dawson Ted M.
- Dawson Valina L.
- Daza Paula
- de Belleroche Jackie
- de Figueiredo Paul
- de la Fuente Jose
- De Martino Luisa
- De Matteis Antonella
- De Meyer Guido
- De Milito Angelo
- De Santi Mauro
- de Souza Wanderley
- De Tata Vincenzo
- De Zio Daniela
- Debnath Jayanta
- Dechant Reinhard
- Decuypere Jean-Paul
- Deegan Shane
- Dehay Benjamin
- Del Bello Barbara
- Del Re Dominic P.
- Delage-Mourroux Regis
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- Delorme-Axford Elizabeth
- Deng Yizhen
- Dengjel Joern
- Denizot Melanie
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- Derrien Benoit
- Deutsch Eric
- Devarenne Timothy P.
- Devenish Rodney J.
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- Di Daniele Nicola
- Di Domenico Fabio
- Di Nardo Alessia
- Di Paola Simone
- Di Pietro Antonio
- Di Renzo Livia
- DiAntonio Aaron
- Diaz-Araya Guillermo
- Diaz-Laviada Ines
- Diaz-Meco Maria T.
- Diaz-Nido Javier
- Dickey Chad A.
- Dickson Robert C.
- Diederich Marc
- Digard Paul
- Dikic Ivan
- Dinesh-Kumar Savithrama P.
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- Ding Zufeng
- Dini Luciana
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- Diwan Abhinav
- Djavaheri-Mergny Mojgan
- Dmytruk Kostyantyn
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- Doetsch Volker
- Dokladny Karol
- Dokudovskaya Svetlana
- Donadelli Massimo
- Dong X. Charlie
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- Li Wei
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- Liang Chengyu
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- Publication venue
- Publication date
- 01/01/2016
- Field of study
Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI) : a phase 3, placebo-controlled, randomised trial
- Author
- Abbott J
- Abe Mitsuru
- Abouglila Kamal
- Abrahamovych Orest
- Abu-Fadel Mazen
- Accini Jose
- Acikel Sadik
- Adhyapak Srilakshmi
- Agaiby John
- Aggarwala Guarav
- Aguilera Roberto M
- Ahn Taehoon
- Aksentiev Sergei
- Akyea-Djamson Ayim
- Al-Amin Jessie
- Al-Faleh Hussam
- Al-Saif Shukri
- Al-Shehri Abdullah
- Al-Zoebi Ayham
- Aladellie Layth
- Albisu Juan
- Alfata Sarab
- Alshehri Halia
- Alvarado Odilon
- Alvarez Jose
- Alvarisqueta Andres
- Amerena John
- Amerena John
- Amin Amit
- Amoroso Giovanni
- Andersson Marielle
- Andersson Marielle
- Andersson Marielle
- Andrawis Nabil
- Andries Alin
- Andrássy Péter
- Angerås Oskar
- Angiolillo Dominick
- Angoulvant Denis
- Ansari Saadat
- Antalik Lubomir
- Aoyama Takahiko
- Appel Karl-Friedrich
- Arana Camilo
- Arat Alev
- Arbanil Hugo
- Arora Satish
- Arriagada German
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- Das Asit
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- de Cosmo Salvatore
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- HASH(0x55aa09b7f480)
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- Labeque Jean N
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- Mediavilla García Juan D
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- Papp Andras
- Park Hun S
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- Parkhomenko Alexander N
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- Passi Rakesh
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- Ramos López Gabriel A
- Randeva Harpal S.
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- Rasputina Lesya
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- Reddy M
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- Sinnaeve Peter
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- Siu Shing C
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- Smith Stephen
- Smolenskaya Olga
- Sokolova Liubov
- Solis Silvana
- Song Yang
- Song Zhifang
- Sonoda Masahiro
- Sookananchai Bancha
- Sopko Karen
- Sorbets Emmanuel
- Sorokina Inna
- Sorokivskyy Mykhaylo
- Sotolongo Rodolfo
- Souza Juliana
- Spinale Francis
- Spinar Jindrich
- Spiridon Marilena
- Srimahachota Suphot
- Srivastava Sunny
- St-Maurice Francois
- Stammen Francis
- Stanchev Georgi
- Stanciulescu Gabriela
- Stania Karol
- Staniloae Cezar
- Stanislavchuk Mykola
- Starczewski Pawel
- Stasinska Teresa
- Steg Philippe G
- Steg Philippe G
- Steg Philippe Gabriel
- Stolarczyk-Sowa Edyta
- Stone Jay
- Storey Robert
- Strand Jorma
- Strandberg Timo
- Strbova Jaroslava
- Striekwold Harry
- Strikwerda Sipke
- Strojek Krzysztof
- Stryuk Raisa
- Su Xi
- Such Slavomir
- Sudnik Wanda
- Sueyoshi Atsushi
- Sugino Hiroshi
- Sugiura Tatsushi
- Suh David
- Suneja Randeep
- Supryadkina Tatiana
- Suresh Damodhar
- Sussex Bruce
- Sutton Jennefer
- Suzuki Masahiro
- Svyshchenko Yevgeniya
- Swanson Neil
- Sychov Oleg
- Syed Faizullah
- Syed Mushtaq
- Sykulski Roman
- Szczasny Marcin
- Sztembis Rafal
- Szynal Slawomir
- Sánchez Raul V
- Sárszegi Zsolt
- Sørensen Torben
- Taggeselle Jens
- Taheri Hamid
- Tahk Seung-Jea
- Takagi Yuichiro
- Takase Shinichi
- Takenaka Takashi
- Takács János
- Tan Edgar
- Tan Michinao
- Tanajura Luiz
- Tao Liang
- Tarasov Nikolay
- Taurio Jyrki
- Teefy Patrick
- Teliatnikova Zinaida
- Tenev Doncho
- Terrelonge Antonio
- Thadani Udho
- The Salem
- The Salem
- The Salem
- Theron Rust
- Thomas Dustin
- Tihchev Tihomir
- Timmermans Patrick
- Tisheva Snezhanka
- Tokmakova Maria
- Tomala Tadeusz
- Tomobuchi Yoshiaki
- Tonnessen Glen
- Torres Gustavo
- Toursarkissian Nicole
- Treasure Charles
- Trenk Dietmar
- Treshkur Tatiana
- Tresukosol Damras
- Tresukosol Damras
- Trevisan Roberto
- Trokis Julien
- Truong Binh
- Tsang Chiu C
- Tse Hung F
- Tseluyko Vira
- Tseng Wei-Kung
- Tsujimoto Mitsuru
- Tsyba Larisa
- Turi Tibor
- Turner Traci
- Turturo Maurizio
- Ueda Osamu
- Uehara Hiroki
- Ueng Kwo-Chang
- Ueno Hideki
- Uguccioni Massimo
- Umpierrez Guillermo
- Urbach Dorothea
- Urban Miroslav
- Urbano Rafael H
- Urbinati Stefano
- Uretsky Barry
- Utsu Noriaki
- Uzunow Anna
- Vaca Carlos
- Vakaliuk Igor
- Valle Timo
- Vallejo Gregorio S
- van de Wal Ruud
- van den Heuvel Christian
- van der Zwaan Coen
- van Eck Martijn
- van Kesteren Henricus
- van Zyl Louis
- Varbella Ferdinando
- Varleta Paola
- Vasconcellos Eduardo
- Vasilyeva Larisa
- Vatova Ralitsa
- Vega Damaris
- Velichko Nataliia
- Vera Tomás R
- Vervoort Geert
- Verwerft Jan
- Viktorova Inna
- Vilamajo Oscar G
- Villablanca Alex
- Vinanska Daniela
- Vinereanu Dragos
- Vinereanu Dragos
- Vishneva Elena
- Vishnevsky Alexander
- Viswanathan Girish
- Vizel Saul
- Viñas Jaime A
- Vlastaris Anthony
- von Engelhardt Charlotte
- von Münchhausen Candy
- Vora Kishor
- Voyce Steven
- Vrolix Mathias
- Vykoukalova Tatiana
- Wang Hao
- Wang Ji-Hung
- Wang Yi-Chih
- Weiderman Ann-Charlotte
- Weigmann Ingo
- Weirick Troy
- Weiss Melvin
- Welch Michelle
- Welter Ryan
- Werner Henri
- Westendorp Iris
- Whelan Alan
- Widimský Petr
- Wierucki Lukasz
- Wilderman Igor
- Wilke Andreas
- Willems Frank
- Willis John
- Wilson Vance
- Wilson William
- Wiseman Alan
- Witek Robert
- Wojcik Ronald
- Wojnowski Lukasz
- Wolzt Michael
- Wong Brian
- Wong Michelle
- Wongvipaporn Chaiyasith
- Woolf Kevin
- Worthley Matthew
- Wozakowska-Kaplon Beata
- Wu Chih-Cheng
- Wu Yen-Wen
- Wujkowski Marek
- Yagensky Andriy
- Yakushin Sergey
- Yalcin Ahmet
- Yamamoto Fumi
- Yaneva Zdravka
- Yeh Hung-I
- Ying Man
- Yokoya Koichi
- Yoon Junghan
- Young Douglas
- Younis Liwa
- Yuan Zuyi
- Zadra Remo
- Zakharov Konstantin
- Zakhary Bosh
- Zaman Azfar
- Zamorano Gómez José L
- Zangroniz Pedro
- Zaniewski Michelle
- Zanini Alejandra
- Zarich Stuart
- Zateyschikova Anna
- Zateyshchikov Dmitry A
- Zebrack James
- Zelazowska Katarzyna
- Zhang Aidong
- Zhang Jian
- Zhang Ningru
- Zhang Wenwu
- Zhao Qiang
- Zhao Qiang
- Zhao Xue-Qiao
- Zharinova Viktoria
- Zidkova Eva
- Zilahi Zsolt
- Zinka Elzbieta
- Zonova Elena
- Zubeeva Galina
- Zucconi-Mazzini Roberto
- Zurakowski Aleksander
- Zólyomi Szilárd
- Édes István
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background:
Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. These patients are generally treated with aspirin. In this trial, we aimed to investigate if these patients would benefit from treatment with aspirin plus ticagrelor.
Methods:
The Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) was a phase 3 randomised, double-blinded, placebo-controlled trial, done in 1315 sites in 42 countries. Patients were eligible if 50 years or older, with type 2 diabetes, receiving anti-hyperglycaemic drugs for at least 6 months, with stable coronary artery disease, and one of three other mutually non-exclusive criteria: a history of previous PCI or of coronary artery bypass grafting, or documentation of angiographic stenosis of 50% or more in at least one coronary artery. Eligible patients were randomly assigned (1:1) to either ticagrelor or placebo, by use of an interactive voice-response or web-response system. The THEMIS-PCI trial comprised a prespecified subgroup of patients with previous PCI. The primary efficacy outcome was a composite of cardiovascular death, myocardial infarction, or stroke (measured in the intention-to-treat population).
Findings:
Between Feb 17, 2014, and May 24, 2016, 11 154 patients (58% of the overall THEMIS trial) with a history of previous PCI were enrolled in the THEMIS-PCI trial. Median follow-up was 3·3 years (IQR 2·8–3·8). In the previous PCI group, fewer patients receiving ticagrelor had a primary efficacy outcome event than in the placebo group (404 [7·3%] of 5558 vs 480 [8·6%] of 5596; HR 0·85 [95% CI 0·74–0·97], p=0·013). The same effect was not observed in patients without PCI (p=0·76, p interaction=0·16). The proportion of patients with cardiovascular death was similar in both treatment groups (174 [3·1%] with ticagrelor vs 183 (3·3%) with placebo; HR 0·96 [95% CI 0·78–1·18], p=0·68), as well as all-cause death (282 [5·1%] vs 323 [5·8%]; 0·88 [0·75–1·03], p=0·11). TIMI major bleeding occurred in 111 (2·0%) of 5536 patients receiving ticagrelor and 62 (1·1%) of 5564 patients receiving placebo (HR 2·03 [95% CI 1·48–2·76], p<0·0001), and fatal bleeding in 6 (0·1%) of 5536 patients with ticagrelor and 6 (0·1%) of 5564 with placebo (1·13 [0·36–3·50], p=0·83). Intracranial haemorrhage occurred in 33 (0·6%) and 31 (0·6%) patients (1·21 [0·74–1·97], p=0·45). Ticagrelor improved net clinical benefit: 519/5558 (9·3%) versus 617/5596 (11·0%), HR=0·85, 95% CI 0·75–0·95, p=0·005, in contrast to patients without PCI where it did not, p interaction=0·012. Benefit was present irrespective of time from most recent PCI.
Interpretation:
In patients with diabetes, stable coronary artery disease, and previous PCI, ticagrelor added to aspirin reduced cardiovascular death, myocardial infarction, and stroke, although with increased major bleeding. In that large, easily identified population, ticagrelor provided a favourable net clinical benefit (more than in patients without history of PCI). This effect shows that long-term therapy with ticagrelor in addition to aspirin should be considered in patients with diabetes and a history of PCI who have tolerated antiplatelet therapy, have high ischaemic risk, and low bleeding risk
Recommended from our members
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one: National Harbor, MD, USA. 9-13 November 2016
- Author
- Aarts Craig
- Abdallah Rehab
- Abdul-Alim Siddiq
- Abolhalaj Milad
- Abtin Fereidoun
- Acheson Anupama
- Acquavella Nicolas
- Adams Gregory P.
- Adams Katherine
- Adams Sharon
- Adamus Tomasz
- Adekandi Madhukara
- Adurthi Sreenivas
- Adusumilli Prasad S.
- Aeffner Famke
- Afentoulis Michael
- Ager Casey
- Aggouraki Despoina
- Agrawal Rajendra
- Agrawal Sudhir
- Agrawal Swati
- Ahlers Christoph Matthias
- Ahmed Nabil
- Ahn Myung Ju
- Ahr Katya
- Ai Midan
- Aiba Rachida-Siham Bel
- Aisner Joseph
- Albertini Mark R.
- Albiges Laurence
- Albright Andrew
- Algazi Alain
- Ali Siraj
- Alicea Candido
- Allen Natalie
- Allersdorfer Andrea
- Alva Ajjai
- Amado Rafael
- Amaria Rodabe
- Ameratunga Malaka
- Amin Asim
- Amor Amira Ben
- Amrhein John
- Anagnostou Valsamo
- Andersen Rikke
- André Thierry
- Andtbacka Robert H. I.
- Angela Omilian
- Angell Helen K.
- Annels Nicola
- Annunziata Christina M.
- Ansa-Addo Ephraim A
- Ansari Tameem
- Antilla Marjukka
- Antonarakis Emmanuel S.
- Aoki Rhonda
- Armand Philippe
- Armstrong Adam
- Arora Kshitij
- Arreaza Gladys
- Ascierto Paolo A.
- Ashworth-Sharpe Julia
- Askmyr David
- Asmellash Senait
- Assadipour Yasmine
- Assenmacher Mario
- Athelogou Maria
- Atkins Michael B.
- Attaf Meriem
- Au Gough
- Au-Young Janice
- Avery Kendra N.
- Ayers Mark
- Azimi Vahid
- Aznar M. Angela
- Backert Linus
- Backes Floor J.
- Bagg Eleanor A. L.
- Bahjat Keith
- Bajorin Dean
- Bakker Lex
- Balakumaran Arun
- Ballesteros-Merino Carmen
- Bander Neil
- Bang Yung-Jue
- Bannerji Rajat
- Baratelli Felicita E.
- Barbee Susannah D.
- Barlesi Fabrice
- Barrett Carl
- Barrett David
- Barth Carola
- Bartkowiak Todd
- Bartlett Nancy
- Basher Fahmin
- Bassett Roland
- Basu Samik
- Bath Natalie
- Batista Luciana
- Bauer Todd
- Bauer Todd M.
- Bauer Todd W.
- Baughman Jan E.
- Bayle J. Henri
- Baylin Stephen
- Beechem Joseph
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- Bellovin David I.
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- Bender James
- Bennett Alan D.
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- Bergamaschi Cristina
- Berger Frank
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- Bessell Catherine A.
- Betts Gareth
- Beyer Sophie
- Bhanot Gyan
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- Bhardwaj Rukmini
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- Caux Christophe
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- Chen Hui
- Chen Jie Qing
- Chen Lawrence
- Chen Lieping
- Chen Mei
- Chen Mingyi
- Chen Shuming
- Chen Xiufen
- Cheng Jonathan
- Cheng Zhi-jie Jey
- Chikina Maria
- Chin Renee
- Chinnasamy Harshini
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- Cohen Lewis
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- Colevas A Dimitrios
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- Conroy Jeff
- Copeland Larry
- Copploa Domenico
- Cordes Lisa
- Cornfeld Mark
- Cortina Luis
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- Coveler Andrew L.
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- Cristescu Razvan
- Crocker Andrea
- Cui Weiguo
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- Cumberbatch Kerwin
- Curran Michael
- Curti Brendan
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- Daenthanasanmak Anusara
- Dai Zhimin
- Damare Sherri
- Dammassa Ernesta
- Danaher Patrick
- Danforth David
- Daud Adil
- Davar Diwakar
- Davenport Anna
- David Larry
- Davies Bronwyn
- Davies Michael A.
- Davis Tom
- De Bono Johann
- De Macedo Mariana Petaccia
- de Oliveira Moacyr Ribeiro
- De Santis Maria
- de Wit Ronald
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- Deeds Michael
- Del Pilar Estevez Diz Maria
- Delcommenne Marc
- Delgoffe Greg M.
- Delismon Judy
- Denisova Galina
- Dennis Lucas
- Deol Abhinav
- Derakhshandeh Roshanak
- DeRenzo Christopher
- Desai Jayesh
- Desai Niyati
- Deshpande Amit
- Deshpande Vikram
- Desjarlais John
- Deveraux Quinn
- DeVito Anna Marie
- Devlin Sean
- Dey Chaitali
- Dhudashia Amit
- di Pietro Alessandra
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- Diaz Luis A.
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- Ding Wei
- Disis Mary L.
- Dobson Jason R.
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- Dolton Garry
- Donda Alena
- Donia Marco
- Donovan Michael Joseph
- doo Chang Young
- Doody Jacqueline
- Dotti Gianpietro
- Dougherty Janna
- Downing Sean
- Dragnev Konstanin
- Drake Charles G.
- Dranoff Glenn
- Draper Lindsey M.
- Drechsel Katharina
- Dreicer Robert
- Dubay Christopher
- Dubey Aparajita
- Dubinett Steven M.
- Dubois Sigrid
- Duhen Rebekka
- Duhen Thomas
- Dummer Reinhard
- Dunaway Dwayne
- Duncan Brynn
- Dundr Pavel
- Duong MyLinh
- Dutour Aurélie
- Dyson Gregory
- D’Amico Leonard
- Eagan Maribeth A.
- Early Brandon
- Eckelman Brendan P.
- Egevad Lars
- Ehrmann Jon M.
- El Rassi Edward
- Elashoff David A.
- Elliott Nathan
- Emens Leisha
- Enblad Gunilla
- Erdag Gulsun
- Ernstoff Marc S.
- Essand Magnus
- Esteller Manel
- Evans Kathy
- Evans Lawrence
- Eyquem Justin
- Fakhrejahani Farhad
- Falchook Gerald
- Fan Aaron
- Fan Frank
- Fang Victoria
- Fantini Massimo
- Fardis Maria
- Faries Mark
- Faroudi Mustapha
- Farrell Michael
- Fast Loren
- Felber Barbara
- Feldman Steven A.
- Feng Dai
- Fernando Ingrid
- Ferris Robert
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- Fieschi Jacques
- Fisher George A.
- Fling Steven
- Flint Paul W.
- Forrest-Hay Alex
- Fosco Dominick
- Foster Aaron E.
- Fotin-Mleczek Mariola
- Fousek Kristen
- Fox Bernard
- Fox Maxine
- Francis Nicole
- Frank Ian
- Frankel Melissa
- Fraser Kathryn
- Frayssinet Véronique
- Freeman Gordon J.
- Freese Katharina
- Frey Alan
- Friedlander Michael L.
- Friedlander Philip
- Fritsch Edward
- Fry Terry
- Fu Siqing
- Fujii Rika
- Fulton Ross B.
- Gajewski Thomas F.
- Galon Jérôme
- Gan Hui
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- Ganesan Shridar
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- Gartrell Benjamin
- Garvin Denise
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- Gause Christine
- Geib James
- Geiss Gary
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- Gerken Claudia
- Gerry Andrew
- Gershan Jill
- Gershenson Zack
- Ghaffari Mahsa
- Ghori Razi
- Gianani Roberto
- Gilden Julia
- Gill Saar
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- Giralt Sergio
- Giri Rajanish
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- Glitza Isabella
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- Gojo Ivana
- Gokuldass Aishwarya
- Goldinger Simone
- Goldman Jonathan W.
- Goldschmidt Hartmut
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- Gonzalez Iliana
- Gonzalez Ricardo
- Gorden Keith
- Gormley Michael
- Gottschalk Stephen
- Govindappa Nagaraja
- Gowda Nagaraj
- Gowda Nagesh
- Graff Jeremy
- Grailer Jamison
- Graziano Robert F.
- Green Daniel S.
- Gregory Gareth
- Greiff Lennart
- Grilley-Olson Juneko E.
- Grimaldi Antonio
- Grose Mark
- Gross Matt
- Grossenbacher Steven
- Grossenbacher Steven K.
- Grupp Stephan
- Gschwendt Juergen
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- Guindani Michele
- Gulley James
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- Gunset Gertrude
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- Hadrup Sine Reker
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- Hall MacLean
- Halmos Balazs
- Hamadani Mehdi
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- Hamieh Mohamad
- Hamilton Garth
- Hammill Joanne
- Hamzaoui Kamel
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- Lin Jin-Ching
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- Nghiem Paul
- Nguyen Andrew
- Nguyen Khue
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- Pelletier Sandy
- Perales Miguel
- Perez-Garcia Arianne
- Perini Rodolfo
- Periyasamy Sankar
- Perlewitz Kelly
- Pestic-Dragovich Lidija
- Petersen Christopher
- Petersen Michael Mørk
- Peterson Tim
- Petroni Gina
- Petruzelka Lubos
- Pfeil Jacob
- Pham Hung
- Piha-Paul Sarina A.
- Pilon-Thomas Shari
- Pinzon-Ortiz Maria
- Piperdi Bilal
- Plimack Elizabeth
- Poehlein Christian
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- Qin Yong
- Qin Zhen
- Quattrini Adriano
- Quinn David
- Rabinovich Brian
- Racolta Adriana
- Rafelson William
- Rahma Osama E.
- Raje Noopur
- Rajurkar Mihir
- Ramachandra Murali
- Ramachandra Raghuveer
- Ramachandran Indu
- Ramakrishna Venky
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- Rao Arjun A.
- Rashid Rumana
- Rattray Rogan
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- Razai Amir S.
- Reagan John L.
- Reckamp Karen
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- Reddy Praveen
- Reeves Jason
- Repasky Elizabeth
- Restifo Nicholas P.
- Reu Simone
- Reuben Alex
- Ribas Antoni
- Ribrag Vincent
- Ricca Jacob
- Richards Allison
- Richards Jon
- Richman Sarah A.
- Rickel Erika
- Riddell Stanley
- Riedlinger Greg
- Riemer Joanne
- Rifkin Robert
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- Robbins Paul F.
- Robida Mark
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- Rocafiguera Albert Oriol
- Roder Heinrich
- Roder Joanna
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- Sikic Branimir I.
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- Steinmetz Sue
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- Stevanovic Sanja
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- Stump Julia
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- Su Shu
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- Sudarshan Naremaddepalli
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- Sun Yongming
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- Thakur Archana
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- Topalian Suzanne
- Toth Kyle
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- Trimble Cornelia L.
- Tsai Katy
- Tsang Kwong
- Tsao Tsu-Shuen
- Tsourkas Andrew
- Tsujikawa Takahiro
- Tufman Amanda
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- Turcotte Simon
- Tykodi Scott
- Uemura Marc
- Uger Robert
- Uhlik Mark
- Uhlin Michael
- Urba Walter
- Uribe Diana
- Vaishampayan Ulka
- Valsesia-Wittmann Sandrine
- van den Brink Marcel R. M.
- Van den Eynde Marc
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- Varadarajan Navin
- Varadhachary Gauri R.
- Vasaturo Angela
- Vaske Charles
- Vasselli James
- Veerapathran Anandaraman
- Velcheti Vamsidhar
- Veninga Henrike
- Vetsika E-K
- Vignali Dario
- Villabona Lisa
- Villalobos Victor M.
- Villarroel Patricio Pérez
- Viller Natasja Nielsen
- Vitale Laura A.
- Vocka Michal
- Volkmer Jens-Peter
- Voss Martin
- Vuyyuru Raja
- Wagner Joel P.
- Wakefield Jessica
- Wakelee Heather A.
- Waldmann Anja
- Waldmann Thomas
- Wallace William D.
- Waller Edmund K.
- Walser Tonya C.
- Walsh William
- Wan Ee
- Wang Chichung
- Wang Chun-Wei
- Wang Daqing
- Wang Gerald
- Wang Hao
- Wang Judy S.
- Wang Lai
- Wang Ziming
- Wardell Seth
- Wargo Jennifer
- Warren Sarah
- Wassman Karl
- Watkins Simon
- Webb Tonya J.
- Weber James
- Weber Jeffrey
- Weber Sharon
- Webster Philippa
- Wei Ziewn
- Weidlick Jeffrey
- Weigel Tracey
- Weinberg Andrew
- Weissbrich Bianca
- Weissman Irving L.
- Wels Winfried S.
- Wennerberg Erik
- Wenthe Jessica
- Westergaard Marie Christine Wulff
- Whetstone Ryan
- White Andrew M.
- White Eileen
- Whiting Sam
- Widger Jenifer
- Wiedenmann Alexander
- Wiedermann Guy
- Wiegand Volker
- Wiener Doris
- Wigginton Jon
- William Loging
- Williams Jason B.
- Williams LaTerrica C.
- Winter Hauke
- Withers Sita
- Witjes J. Alfred
- Witt Kristina
- Wolchok Jedd D.
- Wolfson Martin
- Wondyfraw Nebiyu
- Wong Philip
- Wong Ryan
- Woodman Scott
- Woods David
- Workman Creg
- Wu Catherine J.
- Wu Haiyan
- Wu Jennifer
- Wunderlich John
- Wydro Mateusz
- Xiao Christine
- Xiao Weihua
- Xin Gang
- Xu Hui
- Xue Allen
- Yamamoto Tori
- Yanagawa Jane
- Yang James
- Yang Jason
- Yang Richard
- Yearley Jennifer
- Yee Andrew J.
- Yee Cassian
- Yehuda Dina Ben
- Yigitsoy Mehmet
- Yimer Habte
- Yonemitsu Yoshikazu
- Yoshino Takayuki
- Yu Evan Y.
- Yu Wendy
- Yu Xuezhong
- Yu Zhiya
- Yusko Erik
- Zacharakis Nikolaos
- Zaharoff David
- Zamarin Dmitriy
- Zang Xingxing
- Zanhow Cynthia
- Zappasodi Roberta
- Zarour Hassane
- Zavadova Eva
- Zehn Dietmar
- Zeng Gang
- Zeng Xue
- Zha Yuanyuan
- Zhang Bingqing
- Zhang Congcong
- Zhang Hongjun
- Zhang Hua
- Zhang Hui
- Zhang Jian
- Zhang Jinyu
- Zhang Liping
- Zhang Maggie
- Zhang Wenjun
- Zhang Xiaonan
- Zhang Yayan
- Zhao Fei
- Zhao Xingli
- Zhao Zeguo
- Zhong Shi
- Zhu Baogong
- Zhu Cheng
- Zhu Yifei
- Zi Tong
- Zimarino Carlo
- Zinzani Pier Luigi
- Zoon Kathryn C.
- Zuleger Cindy
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 03/01/2017
- Field of study
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- Abellán Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Akçay Özlem
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia González
- Aleem Muhammad
- Alegre Inês
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz Amorós
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-Díez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
- Amado Fabíola
- Amador Cristina García
- Amanullah Nazli
- Amaral Hélida Aline Tomacheski
- Amaral Luis
- Amin-Tai Hizami
- Aminu Bashiru
- Amir Ahmad Suhaimi
- Ammar Ahmed Siddique
- Ammar Mona Ahmed
- Ammendola Michele
- Ammerata Giorgio
- Amorim Edgar
- Ancans Guntis
- Anderson Tom
- Andrade Diogo
- Andrejevic Predrag
- Andrés Beatriz Díaz San
- Anestiadou Elissavet
- Ang Chin Wee
- Angelo Franceschi
- Anokhin Evgeny
- Anoldo Pietro
- Antakia Ramez
- Anton Majd
- Antonelli Serena
- Antropoli Carmine
- Anula Rocio
- Anwar Jamal
- Anyadike Florence
- Apostolakidou Magda
- Apostolidi Eirini
- Aprea Giovanni
- Arabadzhiev Angel
- Arakawa Satoshi
- Arauz Jazmin
- Aravindan U
- Aremu Abdurrahman
- Aremu Isiaka
- Argawy Osama
- Arican Can
- Arida Zahed Abu
- Armellin Claudia
- Arnaoutoglou Eleni
- Arreguy-Borges Kanthya
- Artigot Mariano
- Arturi Alessandro
- Arulappan Nirupama
- Arya Shobhit
- Arynov Ardak
- Asaad Peter
- Asano Yukio
- Ascari Francesca
- Asgarov Mohsum
- Ashmawy Soad
- Aslam Muhammad Imran
- Assimakopoulou Elena
- Assis Ana
- Astilleta Romina
- Atanasov Boyko
- Atendido Tiffany
- Athanasakis Elias
- Atici Semra Demirli
- Avellaneda Nicholas
- Avellaneda Nicolas
- Avseren Goksu
- Awead Marwa
- Ayandipo Omobolaji
- Aybar Engin
- Aydin Funda
- Aydin Gaye
- Ayoub Kusay
- Aytac Erman
- Aytaç Erman
- Azevedo Jose
- Azevedo Patricia
- Azhar Najia
- Aziz Gowhar
- Azman Zairul Azwan Mohd
- Aşkar Ahmet
- Babatunde Olanrewaju
- Badawi Marwa
- Baek Jeong-Heum
- Baez Noelia Fernández
- Baeza-Murcia Melody
- Bagnardi Francesco
- Baharom Salahudin
- Baik Seung Hyuk
- Baimakhanov Abylai
- Bains Lovenish
- Baker Aleksandra
- Bakmaz Bernarda
- Bala Abubakar Muhammad
- Balaban Vladimir
- Balalis Dimitrios
- Balasubramaniam Dinesh
- Balathayalan Yathev
- Baldi Claudio
- Balestri Riccardo
- Balfour James
- Ballah Abubakar
- Ballian Nikiforos
- Balooshi Iman Al
- Baloyiannis Ioannis
- Bamford Richard
- Bandar Mahdi Al
- Banham Gail
- Bannoud Mohammad Hassan
- Baptista Victor
- Baral Jörg
- Barbalace Nicolas
- Barbato Giuseppe
- Barbosa Anderson
- Bareka Metaxia
- Baris Baver
- Barradas Renato
- Barreda Sara Castillo
- Barrena-Blazquez Silvestra
- Barton Jess
- Bartosiak Katarzyna
- Bashilkina Olga
- Bashir Mohammed
- Basile Raffaele
- Basnyat Pradeep
- Batool Sana
- Bautista Wilson Manuel Sánchez
- Bayhan Zülfü
- Bayo José Manuel Muros
- Bayón Raquel Álvaro
- Baños Pedro Antonio Parra
- Beard David
- Bedzhanyan Arkady
- Behilil Chakib
- Bekele Kebebe
- Belarmino Armin
- Belay Million
- Belev Nikolay
- Bellato Vittoria
- Beltrán de Heredia Juan
- Belvedere Angela
- Benetti Emilio
- Benetti Sara
- Bengueddach Aicha
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- Yew Chor Kuan
- Yılmaz Gülseren
- Yilmazlar Tuncay
- Yiğit Direnç
- Yoldas Tayfun
- Yonekura Hiroshi
- Yorkmui Liu
- Yoshino Kenji
- Younes Lina
- Young Trudi
- Yule Michael
- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- Zadrożna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
- Zanoni Andrea
- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah Kağan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Álvarez-Llano Laura
- Ângelo Miguel Duarte
- ÓSullivan Sara Nuñez
- Özçelik Mehmet Faik
- Ćoza Ivo
- Şanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
- Author
- Abdel-Aziz Amal Kamal
- Abdelfatah Sara
- Abdellatif Mahmoud
- Abdoli Asghar
- Abel Steffen
- Abeliovich Hagai
- Abildgaard Marie H
- Abudu Yakubu Princely
- Acevedo-Arozena Abraham
- Adamopoulos Iannis E
- Adeli Khosrow
- Adolph Timon E
- Adornetto Annagrazia
- Aflaki Elma
- Afshar Elham Ghasemipour
- Agam Galila
- Agarwal Anupam
- Aggarwal Bharat B
- Agnello Maria
- Agostinis Patrizia
- Agrewala Javed N
- Agrotis Alexander
- Aguilar Patricia V
- Ahmad S Tariq
- Ahmed Zubair M
- Ahumada-Castro Ulises
- Aits Sonja
- Aizawa Shu
- Akkoc Yunus
- Akoumianaki Tonia
- Akpinar Hafize Aysin
- Al-Abd Ahmed M
- Al-Akra Lina
- Al-Bari M Abdul Alim
- Al-Gharaibeh Abeer
- Alaoui-Jamali Moulay A
- Alberti Simon
- Alcocer-Gomez Elisabet
- Alcon Soledad Porte
- Alessandri Cristiano
- Ali Muhammad
- Aliwaini Saeb
- Alizadeh Javad
- Almacellas Eugenia
- Almasan Alexandru
- Alonso Alicia
- Alonso Guillermo D
- Altan-Bonnet Nihal
- Altieri Dario C
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- Varela-Nieto Isabel
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- Vasconcelos M Helena
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- Vega-Rubin-de-Celis Silvia
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- Velasco Guillermo
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- Verdier Mireille
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- Wang Maggie Haitian
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- Wang Yu
- Wang Yuqi
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- Warnes Gary
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- Xiao Hengyi
- Xiao Hong-tao
- Xiao Jian
- Xiao Lan
- Xiao Shi
- Xiao Yin
- Xie Baoming
- Xie Chuan-Ming
- Xie Min
- Xie Yuxiang
- Xie Zhiping
- Xie Zhonglin
- Xilouri Maria
- Xu Congfeng
- Xu En
- Xu Haoxing
- Xu Jing
- Xu JinRong
- Xu Liang
- Xu Wen Wen
- Xu Xiulong
- Xue Yu
- Yakhine-Diop Sokhna MS
- Yamaguchi Masamitsu
- Yamaguchi Osamu
- Yamamoto Ai
- Yamashina Shunhei
- Yan Shengmin
- Yan Shian-Jang
- Yan Zhen
- Yanagi Yasuo
- Yang Chuanbin
- Yang Dun-Sheng
- Yang Huan
- Yang Huang-Tian
- Yang Hui
- Yang Jin-Ming
- Yang Jing
- Yang Jingyu
- Yang Ling
- Yang Liu
- Yang Ming
- Yang Pei-Ming
- Yang Qian
- Yang Seungwon
- Yang Shu
- Yang Shun-Fa
- Yang Wannian
- Yang Wei Yuan
- Yang Xiaoyong
- Yang Xuesong
- Yang Yi
- Yang Ying
- Yao Honghong
- Yao Shenggen
- Yao Xiaoqiang
- Yao Yong-Gang
- Yao Yong-Ming
- Yasui Takahiro
- Yazdankhah Meysam
- Yen Paul M
- Yi Cong
- Yin Xiao-Ming
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- Yin Zhangyuan
- Yin Ziyi
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- Yoshida Kiyotsugu
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- Yoshimori Tamotsu
- Yousefi Bahman
- Yu Boxuan
- Yu Haiyang
- Yu Jun
- Yu Jun
- Yu Li
- Yu Ming-Lung
- Yu Seong-Woon
- Yu Victor C
- Yu W Haung
- Yu Zhengping
- Yu Zhou
- Yuan Junying
- Yuan Ling-Qing
- Yuan Shilin
- Yuan Shyng-Shiou F
- Yuan Yanggang
- Yuan Zengqiang
- Yue Jianbo
- Yue Zhenyu
- Yun Jeanho
- Yung Raymond L
- Zacks David N
- Zaffagnini Gabriele
- Zambelli Vanessa O
- Zanella Isabella
- Zang Qun S
- Zanivan Sara
- Zappavigna Silvia
- Zaragoza Pilar
- Zarbalis Konstantinos S
- Zarebkohan Amir
- Zarrouk Amira
- Zeitlin Scott O
- Zeng Jialiu
- Zeng Ju-deng
- Zerovnik Eva
- Zhan Lixuan
- Zhang Bin
- Zhang Donna D
- Zhang Hanlin
- Zhang Hong
- Zhang Hong
- Zhang Honghe
- Zhang Huafeng
- Zhang Huaye
- Zhang Hui
- Zhang Hui-Ling
- Zhang Jianbin
- Zhang Jianhua
- Zhang Jing-Pu
- Zhang Kalin YB
- Zhang Leshuai W
- Zhang Lin
- Zhang Lisheng
- Zhang Lu
- Zhang Luoying
- Zhang Menghuan
- Zhang Peng
- Zhang Sheng
- Zhang Wei
- Zhang Xiangnan
- Zhang Xiao-Wei
- Zhang Xiaolei
- Zhang Xiaoyan
- Zhang Xin
- Zhang Xinxin
- Zhang Xu Dong
- Zhang Yang
- Zhang Yanjin
- Zhang Yi
- Zhang Ying-Dong
- Zhang Yingmei
- Zhang Yuan-Yuan
- Zhang Yuchen
- Zhang Zhe
- Zhang Zhengguang
- Zhang Zhibing
- Zhang Zhihai
- Zhang Zhiyong
- Zhang Zili
- Zhao Haobin
- Zhao Lei
- Zhao Shuang
- Zhao Tongbiao
- Zhao Xiao-Fan
- Zhao Ying
- Zhao Yongchao
- Zhao Yongliang
- Zhao Yuting
- Zheng Guoping
- Zheng Kai
- Zheng Ling
- Zheng Shizhong
- Zheng Xi-Long
- Zheng Yi
- Zheng Zu-Guo
- Zhivotovsky Boris
- Zhong Qing
- Zhou Ao
- Zhou Ben
- Zhou Cefan
- Zhou Gang
- Zhou Hao
- Zhou Hong
- Zhou Hongbo
- Zhou Jie
- Zhou Jing
- Zhou Jing
- Zhou Jiyong
- Zhou Kailiang
- Zhou Rongjia
- Zhou Xu-Jie
- Zhou Yanshuang
- Zhou Yinghong
- Zhou Yubin
- Zhou Zheng-Yu
- Zhou Zhou
- Zhu Binglin
- Zhu Changlian
- Zhu Guo-Qing
- Zhu Haining
- Zhu Hongxin
- Zhu Hua
- Zhu WeiGuo
- Zhu Yanping
- Zhu Yushan
- Zhuang Haixia
- Zhuang Xiaohong
- Zientara-Rytter Katarzyna
- Zimmermann Christine M
- Ziviani Elena
- Zoladek Teresa
- Zong Wei-Xing
- Zorov Dmitry B
- Zorzano Antonio
- Zou Weiping
- Zou Zhen
- Zou Zhengzhi
- Zuryn Steven
- Zwerschke Werner
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field