Angioplasty of the popliteal artery using the Jaguar™ stent

Introduction. The aim of this study was to evaluate the effectiveness of the endovasculartreatment of atherosclerotic stenosis/occlusion of the popliteal artery according to TASC II recommendationsusing the Jaguar SM self-expanding stent depending on the modifiableand unmodifiable risk factors of repeated stenosis/occlusions. Material and methods. The study included 126 men and 46 women aged 46–95 years in 2011–2015.Surgeries were performed in the scheduled and emergency mode. Angioplasty of the popliteal artery withthe Jaguar stent implantation was performed in patients with severe chronic limb ischaemia and critical limbischaemia. Post-operative popliteal artery patency was evaluated in relation to sex, obesity, diabetes, smokingtobacco, and patency of the lower extremity arteries. Results. The postoperative patient follow-up was conducted for 60 months, demonstrating 67% patency after12 months, 59% patency after 24 months, 53% patency after 36 months, 45% patency after 48 months,and 31% patency after 60 months. Conclusions. The Jaguar™ stent implantation is an effective and safe method of treatment of atheroscleroticstenosis and occlusion of the popliteal artery. The occlusion was found in patients with the risk factors such as:obesity, diabetes, and tobacco smoking, limited runoff arteries in the lower leg. Stent fracture did not occur inany patient

KNIPAS – exploring active seafloor spreading processes at segment-scale

Knipovich Ridge passive seismic experiment (KNIPAS) is a state-of-the-art seismological project that studies on segment scale the active spreading processes of an ultraslow mid-ocean ridge. The generation of new ocean floor is accompanied by characteristic seismicity that reflects ongoing spreading events and the physical state of the young lithosphere, and differs widely depending on spreading rate. While fast spreading ridges hardly show earthquakes that are large enough to be recorded on land, magmatic spreading events at the slowest spreading centres seem to be regularly preceded by earthquakes larger than M 5. The depth limit of earthquakes and their presence and absence reveal along-axis variations in the thermal and mechanical regime of the lithosphere. Therefore, it is necessary to record earthquakes locally with ocean bottom seismometers (OBS). Such surveys, however, typically have limited spatial extent and cannot reveal segment-scale spreading processes like along-axis melt flow, while spatially more extended data sets of hydro-acoustically recorded earthquakes yield no information on focal depth and can therefore not constrain lithospheric thickness or temperature. The project KNIPAS instrumented for the first time an entire ridge segment with OBS. During Polarstern cruise PS100 in July-September 2016 we deployed 23 OBS of the German Instrument Pool for Amphibian Seismology (DEPAS) along a 160 km long ridge section that covers Logachev Seamount and a neighbouring volcanic centre. An additional 3 OBS of the Institute of Geophysics, Polish Academy of Sciences, were deployed around Logachev Seamount. The instruments recorded seismicity until July-October 2017 depending on capacity. Cruise MSM67 of Maria S. Merian acquired wide-angle seismic profiles across Logachev Seamount and the subsequent cruise MSM68 successfully recovered all OBS. We now have a comprehensive seismological dataset at hand that will contain despite partly high noise levels in the vicinity of Logachev volcano an expected 9000 earthquakes M>1 and several dozens of well-recorded teleseismic events to study spatial variations of seismicity, thermal structure and lithospheric thickness of an ultraslow spreading ridge. In a joint project we will combine the expertise of our work groups to study seismicity pattern, analyse the large-scale lithospheric structure with modern passive seismic methods to be adapted for the special conditions of marine seismic surveys and to image at high resolution the structure of a volcanic centre

Allergies, asthma or hypersensitivity to NSAIDs - are they an equally important risk factor for the development of a specific CRS phenotype?

Introduction: CRS is a complex systemic disease affecting more than 10% of the population. There are two main types of CRS phenotypes: CRSwNP and CRSsNP. In the Caucasian population, the prevalence of inflammation markers typical of the Th1 profile is observed in CRSsNP, whereas Th2 and Th17 in CRSwNP. Th2 inflammation is observed in the CRSwNP phenotype with concomitant allergies, asthma or hypersensitivity to NSAIDs. Objectives: The aim of the study was to evaluate, based on the authors’ own material, whether allergies, asthma or hypersensitivity to NSAIDs were a risk factor for the development of a specific CRS phenotype. An attempt was also made to investigate the influence of comorbidities on the extent of sinus endoscopic procedures, which depended on the severity of inflammation. Methods: In the years 2006–2015, ESS was performed on 2217 patients with different CRS phenotypes. Patients with an allergy, bronchial asthma and hypersensitivity to NSAIDs were subjected to analysis. Results: Based on logistic regression, it was found that among the mentioned comorbidities, only asthma (P < 0.0001) and hypersensitivity to NSAIDs (P = 0.0007) significantly affect the occurrence of the phenotype with polyps, whereas the impact of allergies is statistically insignificant (P = 0.1909). The relationship between the type of ESS and CRS phenotypes is statistically significant (P < 0.0001). Conclusions: Bronchial asthma and hypersensitivity to NSAIDs have a statistically significant effect on the occurrence of the CRSwNP phenotype. This effect was not observed in allergies. The impact of allergies, asthma and hypersensitivity on the phenotype was observed in the group of patients subjected to the most extensive surgery (ESS 4)

Head and neck lymphomas - a retrospective ten-year observation

Aim of the study: Lymphomas are a heterogeneous group of tumours of lymphoid tissue in which there is an abnormal proliferation of cells of the lymphatic system. The literature notes a gradual increase in the incidence of this type of cancer in the whole population. The aim of the study was to evaluate whether the above tendency occurs in the head and neck area. Material and methods: In the years 2005-2014, at the Otolaryngology and Laryngological Oncology Department of the Upper Silesian Medical Centre in Katowice, 77 cases of lymphoma were recorded, 58 of which were analysed in terms of location, histological type, age and sex of the patient, and the presence of risk factors. Results: The vast majority of them were non-Hodgkin's lymphomas (NHL) - 67.53%. Hodgkin's lymphomas (HL) accounted for only a small fraction of diagnoses (7.79%). In terms of histopathological types, in most cases of NHL, there occurred diffuse large B-cell lymphomas (DLBCL) - 51.92%. The most common location was the lymph nodes, representing the location of the primary lesion in more than half of the cases. As regards the extranodal location, the Waldeyer ring dominated (54.54%) along with the palatal tonsil (40.90%). There has been a significant upward trend, especially in the incidence of NHL

Terapia komórkowa w neurologii — obawy i nadzieje

Opracowanie standardów kontroli bezpieczeństwa i efektywnośc iterapii chorób neurologicznych na podstawie unikatowych właściwości komórek macierzystych stanowi pilne zadanie dl środowiska lekarskiego. Większość z zarejestrowanych do tej pory badań klinicznych oparto na autologicznych przeszczepieniach mezenchymalnych komórek macierzystych (MSC, mesenchymal stem cells, alternatywnie mesenchymal stromal cells) otrzymywanych w warunkach hodowlanych in vitro z różnych, dojrzałych i płodowych tkanek ludzkich, których pierwotne pochodzenie i precyzyjny rodowód pozostają przedmiotem dyskusji. W przeprowadzonych badaniach klinicznych nad terapią komórkami macierzystymi, z których ponad 80% dotyczyło chorób układu nerwowego, nie zaobserwowano poważniejszych powikłań zagrażający życiu i zdrowiu pacjentów. Wskazuje to na wysoki stopień bezpieczeństwa terapii z zastosowaniem komórek macierzystych/progenitorowych pochodzenia tkankowego, jednak ostateczne potwierdzenie tego wniosku wymaga rozszerzonego zakresu badań podstawowych, a przede wszystkim dłuższego czasu obserwacji pacjentów. Należy się także spodziewać, że lepsze poznanie mechanizmów terapeutycznego działania komórek macierzystych wraz z ustaleniem opartych na nich standardów postępowania lekarskiego doprowadzi do zwiększonej skuteczności tych terapii

Physical activity of pregnant women

Korabiusz Katarzyna, Wawryków Agata, Fabian-Danielewska Anna, Stecko Monika, Żukowska Magdalena, Janik Inga, Andrusewicz Wojciech, Torbé Andrzej. Physical activity of pregnant women. Journal of Education, Health and Sport. 2018;8(8):1026-1031. eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1414249 http://ojs.ukw.edu.pl/index.php/johs/article/view/5965 https://pbn.nauka.gov.pl/sedno-webapp/works/876966 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eissn 2391-8306 7 © The Authors 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.08.2018. Revised: 18.08.2018. Accepted: 31.08.2018. Physical activity of pregnant women mgr Katarzyna Korabiusz¹, mgr Agata Wawryków¹, lek. Anna Fabian- Danielewska2, mgr Monika Stecko¹, lek. Magdalena Żukowska2, mgr Inga Janik¹, lek. Wojciech Andrusewicz2, prof. dr hab. n. med. Andrzej Torbé3 ¹ Pomorski Uniwersytet Medyczny w Szczecinie, Studium Doktoranckie Wydziału Nauk o Zdrowiu, ul. Żołnierska 54, 71-210 Szczecin 2 Pomorski Uniwersytet Medyczny w Szczecinie, Studium Doktoranckie Wydziału Lekarskiego, ul. Żołnierska 54, 71-210 Szczecin 3 Pomorski Uniwersytet Medyczny w Szczecinie, Klinika Położnictwa i Ginekologii, ul. Powstańców Wlkp. 72, 70-111 Szczecin Dane autora korespondencyjnego: Katarzyna Korabiusz [email protected] Key words: physical activity, pregnancy. ABSTRACT Every pregnant woman should be aware that her every day health habits affect the child's health, but also her health during pregnancy, delivery and post-partum period. Physical activity plays an important role during pregnancy. It improves the overall physical condition and prevents many ailments of pregnancy. The most important aspect of taking physical activity during pregnancy is the right choice of exercise and regularity and appropriate technique. Due to many benefits of proper exercises during pregnancy, pregnant women should be encouraged and educated in this area

Earthquake Distribution Along an Entire Ridge Segment of the Ultraslow Spreading Knipovich Ridge

The Knipovich Ridge is part of the Arctic Ridge System comprising very slow spreading ridges. In the class of ultraslow spreading ridges, the Knipovich Ridge with its full spreading velocity of 14 – 17 mm/yr is one of the slowest and most obliquely spreading ridges. Magmatic centres along the Knipovich Ridge are mostly defined by seamounts. Amagmatic segments, where tectonism dominates the spreading, act as transfer regions between magmatic centres, since transform faults are absent. The detailed spreading processes at ultraslow spreading ridges still remain unclear. We want to study tectonics and magmatism and their interplay along the Knipovich Ridge by the distribution of local seismicity at segment-scale. We further are interested in how ridge segmentation works in the absence of transform faults. Knipovich Ridge was equipped with a maximum of 30 ocean bottom seismometers along a length of 160 km. The seismometers are positioned between 75.7 and 77.2°N to both sides of the rift valley. They recorded seismicity continuously for on average 11.5 months between summer 2016 and 2017. We used the detection algorithm Lassie and a Kurtosis-based picking algorithm followed by review of the picks by an analyst. The velocity model used for location is defined by well constrained events. We present here first results of this project. We found that earthquakes are not equally distributed along the ridge axis. We observe regions of enhanced seismicity and regions with no or very little seismic activity. Focal depths undulate along the ridge axis up to depths of 20-25 km. We also found clusters of events, one in the north, close to volcanic features, and one close to station 19, south of the Logachev Seamount, a prominent volcanic edifice. The depth distribution of earthquakes reflects the boundary between brittle and ductile deformation, depending on temperature and composition of rocks. This thermal boundary has a varying depth along the rift axis and allows the focussing of melts, e.g. towards Logachev Seamount, where deep seismicity is entirely absent. Seismically less active regions above the band of seismicity may be due to specific composition of rocks, e.g. serpentinised peridotite that leads to ductile reaction on applied stresses. Seismicity clusters may be related to magmatic activity or tectonism of transfer regions

NA61/SHINE online noise filtering using machine learning methods

The NA61/SHINE is a high-energy physics experiment operating at the SPS accelerator at CERN. The physics program of the experiment was recently extended, requiring a significant upgrade of the detector setup. The main goal of the upgrade is to increase the event flow rate from 80Hz to 1kHz by exchanging the read-out electronics of the NA61/SHINE main tracking detectors (Time-Projection-Chambers - TPCs). As the amount of collected data will increase significantly, a tool for online noise filtering is needed. The standard method is based on the reconstruction of tracks and removal of clusters which do not belong to any particle trajectory. However, this method takes a substantial amount of time and resources. A novel approach based on machine learning methods is presented in this proceedings