1,263 research outputs found
Do hospitality management curricula at public higher education institutions in South Africa comply with the standards suggested by a research-based competence framework?
Published ArticleThe employability demands of hospitality employers, combined with the requirements of the 2013 Higher Education (HE) Qualifications Sub-Framework, necessitated a thorough evaluation of the current hospitality management curricula at public HE institutions in South Africa. The evaluation described in this article was based on a comprehensive competence framework developed in a broader study that was aimed at enhancing the employability of hospitality management graduates in South Africa. The outcomes in existing curricula were compared with 127 essential competences in the framework. Hospitality management curricula at public higher education institutions in South Africa do not comply with all the standards suggested by the mentioned research-based competence framework. The key weaknesses identified relate to 36 competences in the framework, which are either not reflected or wrongly represented in the curricula. Arguments for improvement are substantiated by the results of an extensive Delphi evaluation of the competences in the framework by 38 experts in the field
The design of an adult learning programme : a theory-guided evaluation of learning needs
Published ArticleThe learning design in programmes for adult learners in higher education does not usually make provision for the specific characteristics and learning needs of adults. The question that directed the evaluation study undertaken was whether the learning design in a specific programme reflected the learning needs of the predominantly adult learners in the programme. Adult learning principles incorporated in an integrated four-part model provided a theoretical framework for the research. The results suggested that some of the learning needs/preferences of the adult respondents were addressed but cautioned leaders that certain areas of the learning design in the programme needed improvement
CPM: a deformable model for shape recovery and segmentation based on charged particles
Ruling out the light weakly interacting massive particle explanation of the Galactic 511 keV line
Exploring dark matter microphysics with galaxy surveys
We use present cosmological observations and forecasts of future experiments to illustrate the power of large-scale structure (LSS) surveys in probing dark matter (DM) microphysics and unveiling potential deviations from the standard ΛCDM scenario. To quantify this statement, we focus on an extension of ΛCDM with DM-neutrino scattering, which leaves a distinctive imprint on the angular and matter power spectra. After finding that future CMB experiments (such as COrE+) will not significantly improve the constraints set by the Planck satellite, we show that the next generation of galaxy clustering surveys (such as DESI) could play a leading role in constraining alternative cosmologies and even have the potential to make a discovery. Typically we find that DESI would be an order of magnitude more sensitive to DM interactions than Planck, thus probing effects that until now have only been accessible via N-body simulations
Synthesis of oligodeoxyribonucleotides containing a tricyclic thio analogue of O6-methylguanine and their recognition by MGMT and Atl1
Promutagenic O6-alkylguanine adducts in DNA are repaired in humans by O6-methylguanine-DNA-methyltransferase (MGMT) in an irreversible reaction. Here we describe the synthesis of a phosphoramidite that allows the preparation of oligodeoxyribonucleotides (ODNs) containing a novel tricyclic thio analogue of O6-methylguanine in which the third ring bridges the 6-thio group and C7 of a 7-deazapurine. These ODNs are very poor substrates for MGMT and poorly recognised by the alkyltransferase-like protein, Atl1. Examination of the active sites of both MGMT and Atl1 suggest large steric clashes hindering binding of the analogue. Such analogues, if mutagenic, are likely to be highly toxic
Cosmological parameter estimation using Very Small Array data out to ℓ= 1500
We estimate cosmological parameters using data obtained by the Very Small Array (VSA) in its extended configuration, in conjunction with a variety of other cosmic microwave background (CMB) data and external priors. Within the flat Λ cold dark matter (ΛCDM) model, we find that the inclusion of high-resolution data from the VSA modifies the limits on the cosmological parameters as compared to those suggested by the Wilkinson Microwave Anisotropy Probe (WMAP) alone, while still remaining compatible with their estimates. We find that Ωbh2= 0.0234+0.0012−0.0014, Ωdmh2= 0.111+0.014−0.016, h= 0.73+0.09−0.05, nS= 0.97+0.06−0.03, 1010AS= 23+7−3 and τ= 0.14+0.14−0.07 for WMAP and VSA when no external prior is included. On extending the model to include a running spectral index of density fluctuations, we find that the inclusion of VSA data leads to a negative running at a level of more than 95 per cent confidence ( nrun=−0.069 ± 0.032 ), something that is not significantly changed by the inclusion of a stringent prior on the Hubble constant. Inclusion of prior information from the 2dF galaxy redshift survey reduces the significance of the result by constraining the value of Ωm. We discuss the veracity of this result in the context of various systematic effects and also a broken spectral index model. We also constrain the fraction of neutrinos and find that fν < 0.087 at 95 per cent confidence, which corresponds to mν < 0.32 eV when all neutrino masses are equal. Finally, we consider the global best fit within a general cosmological model with 12 parameters and find consistency with other analyses available in the literature. The evidence for nrun < 0 is only marginal within this model
An empirical bioethical examination of Norwegian and British doctors' views of responsibility and (de)prioritization in healthcare
In a world with limited resources, allocation of resources to certain individuals and conditions inevitably means fewer resources allocated to other individuals and conditions. Should a patient's personal responsibility be relevant to decisions re- garding allocation? In this project we combine the normative and the descriptive, conducting an empirical bioethical examination of how both Norwegian and British doctors think about principles of responsibility in allocating scarce healthcare re- sources. A large proportion of doctors in both countries supported including re- sponsibility for illness in prioritization decisions. This finding was more prominent in zero‐sum scenarios where allocation to one patient means that another patient is denied treatment. There was most support for incorporating prospective responsi- bility (through patient contracts), and low support for integrating responsibility into co‐payments (i.e. through requiring responsible patients to pay part of the costs of treatment). Finally, some behaviours were considered more appropriate grounds for deprioritization (smoking, alcohol, drug use)—potentially because of the certainty of impact and direct link to ill health. In zero‐sum situations, prognosis also influenced prioritization (but did not outweigh responsibility). Ethical implications are discussed. We argue that the role that responsibility constructs appear to play in doctors' decisions indicates a needs for more nuanced—and clear—policy. Such policy should account for the distinctions we draw between responsibility‐sensitive and prog- nostic justifications for deprioritization
Spectra and energy levels of the trivalent ytterbium ion doped into lithium niobate by thermal indiffusion
An x-cut LiNbO3 substrate has been doped with Yb3+ ions by thermal diffusion from an Yb metal film of thickness 7nm. Polarised absorption and fluorescence spectra of the dopant ion have been measured using Ti-diffused y-propagating channel waveguides prepared in the doped region. Yb is a diode- pumpable laser ion with characteristics which can be compared favourably with those of Nd in some respects; for example the small energy difference between pump and laser photons reduces thermal load facilitating high power operation. A waveguide laser geometry is particularly advantageous for Yb due to the quasi-3-level nature of the laser transition. The simple fabrication technique described here has been used to produce a system which may have the potential to operate as an Yb waveguide laser in an electro-optic host crystal
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