High performance management practices in owner-managed SMEs

Objectives: While there is extensive management and academic literature on the topic area of high performance management practices (HPPs) internationally, research on HPPs in the Australian context is limited. Furthermore, research on HPPs has focused predominantly on large organisations and is largely a new direction for research in SMEs. This study attempts to fill some of the gaps in existing studies by considering a wide range of HPPs in Australian SMEs, with particular focus on owner managed SMEs. The objective of this paper is to examine the extent and nature of HPPs in owner managed Australian SMEs and the impact of certain organisational characteristics on these practices. The research questions under examination include: What is the prevalence of HPPs in owner managed Australian SMEs?; and what is the impact of firm size, the presence of a HR manager, and the existence of a strategic plan on HPPs in SMEs? Prior work: Undertaking this research is justified on the basis of: there is a gap in the theory relating to HPPs in SMEs and in particular owner managed SMEs, owing to the fact that most studies on HPPs are based in large organisations; globalisation and the pace of economic change are forces that are driving the need for greater understanding of HPPs (Burke 2002); and there are high expectations for growth and performance of SMEs in the economic growth and development plans for the Asia Pacific and Australian region (Asia Pacific Economic Cooperation 2002). Approach: A survey questionnaire was sent out to 4000 Australian small and medium-sized enterprises (35% response rate). A Dun and Bradstreet database was used and a stratified sample employed. A chi-square analysis was employed to determine whether there were significant differences in relation to high performance practices in small vs. medium organisations, SMEs with and without a HR manager; and organisations with and without a strategic plan. Results: The results of this study indicate that the overall picture regarding the incidence of high performance practices in Australian owner managed SMEs looks quite bleak. Significant positive relationships were found between demographic variables and HPPs in SMEs. Implications: Large firm solutions may not be appropriate. A more balanced approach to prescribing and researching management solutions in SMEs is needed; an approach with a greater emphasis on the SME sector. Value: This paper will provide an improved understanding of HPPs in Australian SMEs which will help the sector to better meet performance expectations

Regulation of nicotinic acetylcholine receptors by tyrosine kinases in the peripheral and central nervous system: same players, different roles

Abstract.: Nicotinic acetylcholine receptors (nAChRs) exist in many subtypes and are found in the peripheral and central nervous system where they mediate or modulate synaptic transmission. We review how tyrosine phosphorylation and kinases regulate muscle and neuronal nAChRs. Interestingly, although some of the same kinase players interact with the various receptor subtypes, the functional consequences are different. While concerted action of MuSK, Abl- and Src-family kinases (SFKs) regulates the synaptic distribution of nAChRs at the neuromuscular junction, SFKs activate heteromeric neuronal nAChRs in adrenal chromaffin cells, thereby enhancing catecholamine secretion. In contrast, the activity of homomeric neuronal nAChRs, as found in the hippocampus, is negatively regulated by tyrosine phosphorylation and SFKs. It appears that tyrosine kinases provide the means to regulate all nAChRs; but the functional consequences, even those caused by the same kinase family, are specific for each receptor subtype and locatio

Using mutual information to measure order in model glass-formers

Whether or not there is growing static order accompanying the dynamical heterogeneity and increasing relaxation times seen in glassy systems is a matter of dispute. An obstacle to resolving this issue is that the order is expected to be amorphous and so not amenable to simple order parameters. We use mutual information to provide a general measurement of order that is sensitive to multi-particle correlations. We apply this to two glass-forming systems (2D binary mixtures of hard disks with different size ratios to give varying amounts of hexatic order) and show that there is little growth of amorphous order in the system without crystalline order. In both cases we measure the dynamical length with a four-point correlation function and find that it increases significantly faster than the static lengths in the system as density is increased. We further show that we can recover the known scaling of the dynamic correlation length in a kinetically constrained model, the 2-TLG.Comment: 10 pages, 12 Figure

Quantum key distribution with realistic states: photon-number statistics in the photon-number splitting attack

Quantum key distribution can be performed with practical signal sources such as weak coherent pulses. One example of such a scheme is the Bennett-Brassard protocol that can be implemented via polarization of the signals, or equivalent signals. It turns out that the most powerful tool at the disposition of an eavesdropper is the photon-number splitting attack. We show that this attack can be extended in the relevant parameter regime such as to preserve the Poissonian photon number distribution of the combination of the signal source and the lossy channel.Comment: 4 page

Synthesis of analogues of (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate, an isoprenoid precursor and human γδ T cell activator

(E)-1-Hydroxy-2-methyl-but-2-enyl 4-diphosphate (HMBPP) is an intermediate in the non-mevalonate pathway for the biosynthesis of isoprenoids and also serves as a very strong activator of human gamma delta T cells expressing V gamma 9V delta 2 receptors. This paper describes the synthesis of analogues of HMBPP, in which the diphosphate group is replaced by potential isosteric moieties, i.e., carbamate, N-acyl-N'-oxy sulfamate, or aminosulfonyl carbamate functionalities. The potential of the synthesized analogues to stimulate V gamma 9/V delta 2 T cell response or to inhibit GcpE and LytB, the last enzymes in the non-mevalonate pathway, was assessed

Quantum private queries

We propose a cheat sensitive quantum protocol to perform a private search on a classical database which is efficient in terms of communication complexity. It allows a user to retrieve an item from the server in possession of the database without revealing which item she retrieved: if the server tries to obtain information on the query, the person querying the database can find it out. Furthermore our protocol ensures perfect data privacy of the database, i.e. the information that the user can retrieve in a single queries is bounded and does not depend on the size of the database. With respect to the known (quantum and classical) strategies for private information retrieval, our protocol displays an exponential reduction both in communication complexity and in running-time computational complexity.Comment: 4 pages, 1 figur