Twentieth Century Etiquette (Part 3)

The full title for this book is Twentieth Century Etiquette: An Up-To-Date Book for Polite Society Containing Rules for Conduct in Public, Social and Private Life, at Home and Abroad including suggestions for oriental teas, church festivals, charity socials, costume parties, bazaars, Germans, indoor games, outdoor sports, tally-ho parties, masquerades, etc., etc. also correct dress for weddings, receptions, and all other occasions designed for both men and women, young and old. This last section of the book contains chapters titled Servants, Maids and Assistants, Births and Christenings, Funerals and Mourning, Special Suggestions, Graceful Development of the Body, Unselfishness-The Key to Graciousness, The Possibilities of Women, Women in Business, Real and Fancied Wrongs, Higher Culture, The Shaping of Character, Women Beautiful, and The Language of the Hand.https://openworks.wooster.edu/motherhomeheaven/1101/thumbnail.jp

Social Culture: A Manual of Etiquette and Deportment (Part One)

The full title of this book as listed on the title page is Social Culture: An Up-to-Date Book for Polite Society Containing Rules for Conduct in Public, Social and Private Life, at Home and Abroad Including Suggestions for Oriental Teas, Church Festivals, Charity Socials, Costume Parties, Bazaars, Germans, Indoor Games, Outdoor Sports, Tally-Ho Parties, Masquerades, Etc., Etc. Also Correct Dress for Weddings, Receptions, and All Other Occasions Designed for Both Men and Women, Young and Old. It is also, Embellished with nearly half a hundred full page engravings and numerous drawings by George Speil.https://openworks.wooster.edu/motherhomeheaven/1093/thumbnail.jp

Twentieth Century Etiquette (Part 2)

The full title for this book is Twentieth Century Etiquette: An Up-To-Date Book for Polite Society Containing Rules for Conduct in Public, Social and Private Life, at Home and Abroad including suggestions for oriental teas, church festivals, charity socials, costume parties, bazaars, Germans, indoor games, outdoor sports, tally-ho parties, masquerades, etc., etc. also correct dress for weddings, receptions, and all other occasions designed for both men and women, young and old. This second section of the book includes chapters about Telephoning-Business and Social, Social Etiquette at Washington, Calling-When and How, Dinners and Luncheons, Etiquette at the Table, Receptions, Lectures, Church, Etc., Costume Parties and What to Wear, Dress-Its Attractiveness and Appropriateness, Correspondence-Business and Social, Horseback Riding and Driving, Cycling, Golf, Dancing and Games, Courtship and Its Demands, Weddings and How to Conduct Them, Anniversaries and How to Celebrate Them, and Traveling-Home and Abroad.https://openworks.wooster.edu/motherhomeheaven/1100/thumbnail.jp

Social Culture: A Manual of Etiquette and Deportment (Part Two)

The full title of this book as listed on the title page is, Social Culture: An Up-to-Date Book for Polite Society Containing Rules for Conduct in Public, Social and Private Life, at Home and Abroad Including Suggestions for Oriental Teas, Church Festivals, Charity Socials, Costume Parties, Bazaars, Germans, Indoor Games, Outdoor Sports, Tally-Ho Parties, Masquerades, Etc., Etc. Also Correct Dress for Weddings, Receptions, and All Other Occasions Designed for Both Men and Women, Young and Old. It is also, Embellished with nearly half a hundred full page engravings and numerous drawings by George Speil.https://openworks.wooster.edu/motherhomeheaven/1094/thumbnail.jp

Twentieth Century Etiquette (Part 1)

The full title for this book is Twentieth Century Etiquette: An Up-To-Date Book for Polite Society Containing Rules for Conduct in Public, Social and Private Life, at Home and Abroad including suggestions for oriental teas, church festivals, charity socials, costume parties, bazaars, Germans, indoor games, outdoor sports, tally-ho parties, masquerades, etc., etc. also correct dress for weddings, receptions, and all other occasions designed for both men and women, young and old. This first section of the book contains chapters entitled The Makers of Manners, The Test of the Lady and Gentleman, Importance of Social Observances, Home-The Life Immortal, Little Folks-Their Entertainment and Dress, Self-Consciousness-How to Overcome It, Introductions-Their Importance, Greeting and Leavetaking, Conversation, Etiquette of School Days, Going Into Society, Misses and Unmarried Women, What Etiquette Demands of a Gentleman, Obligations of Bachelors, and Etiquette in the Street.https://openworks.wooster.edu/motherhomeheaven/1099/thumbnail.jp

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Safety and immunogenicity of a variant-adapted SARS-CoV-2 recombinant protein vaccine with AS03 adjuvant as a booster in adults primed with authorized vaccines: a phase 3, parallel-group studyResearch in context

Summary: Background: In a parallel-group, international, phase 3 study (ClinicalTrials.gov NCT04762680), we evaluated prototype (D614) and Beta (B.1.351) variant recombinant spike protein booster vaccines with AS03-adjuvant (CoV2 preS dTM-AS03). Methods: Adults, previously primed with mRNA (BNT162b2, mRNA-1273), adenovirus-vectored (Ad26.CoV2.S, ChAdOx1nCoV-19) or protein (CoV2 preS dTM-AS03 [monovalent D614; MV(D614)]) vaccines were enrolled between 29 July 2021 and 22 February 2022. Participants were stratified by age (18–55 and ≥ 56 years) and received one of the following CoV2 preS dTM-AS03 booster formulations: MV(D614) (n = 1285), MV(B.1.351) (n = 707) or bivalent D614 + B.1.351 (BiV; n = 625). Unvaccinated adults who tested negative on a SARS-CoV-2 rapid diagnostic test (control group, n = 479) received two primary doses, 21 days apart, of MV(D614). Anti-D614G and anti-B.1.351 antibodies were evaluated using validated pseudovirus (lentivirus) neutralization (PsVN) assay 14 days post-booster (day [D]15) in 18–55-year-old BNT162b2-primed participants and compared with those pre-booster (D1) and on D36 in 18–55-year-old controls (primary immunogenicity endpoints). PsVN titers to Omicron BA.1, BA.2 and BA.4/5 subvariants were also evaluated. Safety was evaluated over a 12-month follow-up period. Planned interim analyses are presented up to 14 days post-last vaccination for immunogenicity and over a median duration of 5 months for safety. Findings: All three boosters elicited robust anti-D614G or -B.1.351 PsVN responses for mRNA, adenovirus-vectored and protein vaccine-primed groups. Among BNT162b2-primed adults (18–55 years), geometric means of the individual post-booster versus pre-booster titer ratio (95% confidence interval [CI]) were: for MV (D614), 23.37 (18.58–29.38) (anti-D614G); for MV(B.1.351), 35.41 (26.71–46.95) (anti-B.1.351); and for BiV, 14.39 (11.39–18.28) (anti-D614G) and 34.18 (25.84–45.22 (anti-B.1.351). GMT ratios (98.3% CI) versus post-primary vaccination GMTs in controls, were: for MV(D614) booster, 2.16 (1.69; 2.75) [anti-D614G]; for MV(B.1.351), 1.96 (1.54; 2.50) [anti-B.1.351]; and for BiV, 2.34 (1.84; 2.96) [anti-D614G] and 1.39 (1.09; 1.77) [anti-B.1.351]. All booster formulations elicited cross-neutralizing antibodies against Omicron BA.2 (across priming vaccine subgroups), Omicron BA.1 (BNT162b2-primed participants) and Omicron BA.4/5 (BNT162b2-primed participants and MV D614-primed participants). Similar patterns in antibody responses were observed for participants aged ≥56 years. Reactogenicity tended to be transient and mild-to-moderate severity in all booster groups. No safety concerns were identified. Interpretation: CoV2 preS dTM-AS03 boosters demonstrated acceptable safety and elicited robust neutralizing antibodies against multiple variants, regardless of priming vaccine. Funding: Sanofi and Biomedical Advanced Research and Development Authority (BARDA)

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

non present