4,368 research outputs found
Discovery Prospects for NMSSM Higgs Bosons at the High-Energy Large Hadron Collider
We investigate the discovery prospects for NMSSM Higgs bosons during the
13~TeV run of the LHC. While one of the neutral Higgs bosons is demanded to
have a mass around 125~GeV and Standard Model (SM)-like properties, there can
be substantially lighter, nearby or heavier Higgs bosons, that have not been
excluded yet by LEP, Tevatron or the 8~TeV run of the LHC. The challenge
consists in discovering the whole NMSSM Higgs mass spectrum. We present the
rates for production and subsequent decay of the neutral NMSSM Higgs bosons in
the most promising final states and discuss their possible discovery. The
prospects for pinning down the Higgs sector of the Natural NMSSM will be
analysed taking into account alternative search channels. We give a series of
benchmark scenarios compatible with the experimental constraints, that feature
Higgs-to-Higgs decays and entail (exotic) signatures with multi-fermion and/or
multi-photon final states. These decay chains furthermore give access to the
trilinear Higgs self-couplings. We briefly discuss the possibility of
exploiting coupling sum rules in case not all the NMSSM Higgs bosons are
discovered
Next-to-Leading Order NMSSM Decays with CP-odd Higgs Bosons and Stops
We compute the full next-to-leading order supersymmetric (SUSY) electroweak
(EW) and SUSY-QCD corrections to the decays of CP-odd NMSSM Higgs bosons into
stop pairs. In our numerical analysis we also present the decay of the heavier
stop into the lighter stop and an NMSSM CP-odd Higgs boson. Both the EW and the
SUSY-QCD corrections are found to be significant and have to be taken into
account for a proper prediction of the decay widths.Comment: 28 pages, 10 figure
Dynamic response of a flexible space beam
Dynamic response of a candidate flexible beam for a space experiment on control of flexible structures is investigated. Studies of natural frequencies reveal a beam length in which torsion and bending frequencies virtually coincide. Eccentric tip mass causes small shifts in natural frequencies but introduces coupled torsional/bending mode shapes. Transient response studies indicate significant effects on tip responses of low damping and first bending mode excitation at higher frequencies. Steady state response suggest displacement and acceleration measurements could be made up to 5 to 12 Hz for the actuator forces/torques assumed
Marriage: Passion, Friendship & Vocation
The question that drives this essay is whether friendship is necessary for the spousal relationship, or if romantic passion alone is sufficient. It is divided into three sections. The first examines why relationships based upon romantic passion alone cannot sustain the spousal relationship. Since spousal relationships based upon romantic passion alone tend toward the disintegration of the relationship and the reduction of the other person to mere means alone (and not as an end in himself), it becomes clear that some other kind of relationship is needed. The second section of the essay explores the nature of friendship and argues that it is the proper context for a flourishing marital relationship. Friendship is necessary for marriage, among other reasons, as the love of benevolence is the only kind of love by which persons can be loved according to their dignity. Spousal friendship prevents the harms raised in the first section of this essay and facilitates the context for the expression of betrothed love. The third section of the essay explores how friendship with God helps to sustain spousal friendship.
This essay relies largely upon the writings of Aristotle, Saint Augustine, Saint Thomas Aquinas, Saint John Paul II, and numerous others. Rooted largely within the Catholic theological and sacramental tradition, this essay rests upon a way of a deeply personalistic anthropology that has matured over several centuries’ worth of collective data of human experience. Human creatures are made by God and are ordered to Him—they are made by love for love—and the human heart will ever remain restless until it finds itself in a total gift of self to the Lord
Precision Measurements of Higgs Couplings: Implications for New Physics Scales
The measured properties of the recently discovered Higgs boson are in good
agreement with predictions from the Standard Model. However, small deviations
in the Higgs couplings may manifest themselves once the currently large
uncertainties will be improved as part of the LHC program and at a future Higgs
factory. We review typical new physics scenarios that lead to observable
modifications of the Higgs interactions. They can be divided into two broad
categories: mixing effects as in portal models or extended Higgs sectors, and
vertex loop effects from new matter or gauge fields. In each model we relate
coupling deviations to their effective new physics scale. It turns out that
with percent level precision the Higgs couplings will be sensitive to the
multi-TeV regime.Comment: Invited review for Journal of Physics G, 33pp; v2: references added
and improved discussion of operator basis in section 2.
Clinical relevance of circulating tumour cells in the bone marrow of patients with SCCHN
Background: Clinical outcome of patients with head and neck squamous cell carcinoma (SCCHN) depends on several risk factors like the presence of locoregional lymph node or distant metastases, stage, localisation and histologic differentiation of the tumour. Circulating tumour cells in the bone marrow indicate a poor prognosis for patients with various kinds of malignoma. The present study examines the clinical relevance of occult tumour cells in patients suffering from SCCHN. Patients and Methods: Bone marrow aspirates of 176 patients suffering from SCCHN were obtained prior to surgery and stained for the presence of disseminated tumour cells. Antibodies for cytokeratin 19 were used for immunohistochemical detection with APAAP on cytospin slides. Within a clinical follow-up protocol over a period of 60 months, the prognostic relevance of several clinicopathological parameters and occult tumour cells was evaluated. Results: Single CK19-expressing tumour cells could be detected in the bone marrow of 30.7% of the patients. There is a significant correlation between occult tumour cells in the bone marrow and relapse. Uni- and multivariate analysis of all clinical data showed the metastases in the locoregional lymph system and detection of disseminated tumour cells in the bone marrow to be statistically highly significant for clinical prognosis. Conclusion: The detection of minimal residual disease underlines the understanding of SCCHN as a systemic disease. Further examination of such cells will lead to a better understanding of the tumour biology, as well as to improvement of diagnostic and therapeutic strategies
Physics at CERN's Antiproton Decelerator
The Antiproton Decelerator of CERN began operation in 1999 to serve
experiments for studies of CPT invariance by precision laser and microwave
spectroscopy of antihydrogen () and antiprotonic helium
(). The first 12 years of operation saw cold
synthesized by overlapping clouds of positrons () and antiprotons
() confined in magnetic Penning traps. Cold was also
produced in collisions between Rydberg positronium atoms and .
Ground-state was later trapped for up to s in a
magnetic bottle trap, and microwave transitions excited between its hyperfine
levels. In the atom, UV transitions were measured to a
precision of (2.3-5) by sub-Doppler two-photon laser
spectroscopy. From this the antiproton-to-electron mass ratio was determined as
1836.1526736(23), which agrees with the p value. Microwave
spectroscopy of yielded a measurement of the
magnetic moment with a precision of 0.3%. More recently the magnetic moment of
a single confined in a Penning trap was measured with a higher
precision, as in nuclear
magnetons. Other measurements include the energy loss of 1-100 keV
traversing conductor and insulator targets; the cross sections of <10 keV
ionizing gas targets; and the cross sections of 5-MeV
annihilating on target foils via nuclear collisions. The biological
effectiveness of beams destroying cancer cells was measured as a
possible method for radiological therapy. New experiments under preparation
attempt to measure the gravitational acceleration of or
synthesize \obar{\rm H}^+.Comment: To be published in Progress in Particle and Nuclear Physic
Enhancement in Motor Learning through Genetic Manipulation of the Lynx1 Gene
The cholinergic system is a neuromodulatory neurotransmitter system involved in a variety of brain processes, including
learning and memory, attention, and motor processes, among others. The influence of nicotinic acetylcholine receptors of
the cholinergic system are moderated by lynx proteins, which are GPI-anchored membrane proteins forming tight
associations with nicotinic receptors. Previous studies indicate lynx1 inhibits nicotinic receptor function and limits neuronal
plasticity. We sought to investigate the mechanism of action of lynx1 on nicotinic receptor function, through the generation
of lynx mouse models, expressing a soluble version of lynx and comparing results to the full length overexpression. Using
rotarod as a test for motor learning, we found that expressing a secreted variant of lynx leads to motor learning
enhancements whereas overexpression of full-length lynx had no effect. Further, adult lynx1KO mice demonstrated
comparable motor learning enhancements as the soluble transgenic lines, whereas previously, aged lynx1KO mice showed
performance augmentation only with nicotine treatment. From this we conclude the motor learning is more sensitive to
loss of lynx function, and that the GPI anchor plays a role in the normal function of the lynx protein. In addition, our data
suggests that the lynx gene plays a modulatory role in the brain during aging, and that a soluble version of lynx has
potential as a tool for adjusting cholinergic-dependent plasticity and learning mechanisms in the brain
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