Versatzstücke

Bei studentischen Entwürfen, die sich mit dem Bauen im Bestand befassen, zeigt sich in jüngerer Zeit ein gestiegenes Interesse nicht nur an denkmalpflegerischen Fragen, sondern auch am historischen Material als solchem. Man schätzt es im Sinne eines begrenzt verfügbaren, daher wertvollen Reservoirs, aus dem man auf vielfältige Weise schöpfen kann, z. B. durch Integration von Recycling-Materialien oder aber auch durch Anleihen an den historischen Formenapparat. Dabei bedient man sich einer alten Methode: des Arbeitens mit Versatzstücken. Per Definition ist ein Versatzstück der bewegliche, beliebig zu versetzende Teil einer Bühnendekoration. Im übertragenen Sinne ist damit jedoch ein künstlerisches Verfahren gemeint, nämlich Teile eines Werkes in einem anderen Kontext – einem neuen Werk – schöpferisch wiederzuverwenden. Dieses Einfügen am neuen Ort ist in der Architektur meist mit einem räumlichen „Versetzen“ verbunden. Stets jedoch geht es auch um eine zeitliche Differenz: Denn das Versatzstück stellt einerseits den Bezug zu einem älteren Kontext her und veranschaulicht andererseits den Bruch, das Anders- und Fremdartige. Daher wohnt einer derartigen Zwiesprache zwischen Alt und Neu häufig ein ästhetisch bereicherndes, zugleich ein narratives Moment inne. Vom kunsthistorischen Begriff der „Spolie“ unterscheidet sich derjenige des „Versatzstückes“ durch seine größere Offenheit für verschiedene Interpretationen, wie die Beiträge dieses Heftes belegen. Allen gemeinsam ist die Frage nach den Bedeutungen, die man den jeweiligen Relikten beimisst: Sind derartige Wiederverwendungen pragmatisch oder programmatisch intendiert? Stehen ökonomische, politisch-ideologische, religiöse oder künstlerische Motive dahinter? Die Beiträge des Heftes zeigen, dass es sich wohl meist um eine Gemengelage handelt – mit allerdings unterschiedlichen Gewichtungen je nach Bauaufgabe, Anspruchsniveau und Zeitgeist. In der Gegenwart ist ein Arbeiten mit Versatzstücken u. a. ökologisch, vor allem aber wohl ästhetisch motiviert. Mit dem auf seine Verletzlichkeit verweisenden Fragment, mit dem durch Altersspuren angereicherten Relikt lassen sich Qualitäten des Poetischen erzeugen, die wir in einer weitgehend durchrationalisierten Welt zu schätzen wissen. In Reaktion auf die Spezifik des wiederverwendeten Materials scheint ein von normativen Vorstellungen abweichendes Arbeiten hier nicht nur erlaubt, sondern stellt sich oft als ein Gewinn heraus

Zur Beschäftigungsentwicklung in der Region Hannover – Ein Vergleich mit 12 deutschen Verdichtungsräumen

Der vorliegende Beitrag untersucht die Beschäftigungsentwicklung in der Region Hannover für den Zeitraum 1999 bis 2006 und stellt sie zwölf weiteren deutschen Verdichtungsräumen gegenüber. Unter Verwendung des Betriebs-Historik-Panels des Institutes für Arbeitsmarkt- und Berufsforschung (IAB) werden neben der Beschäftigungsentwicklung im Aggregat auch die dahinter liegenden Bruttoströme analysiert um somit auch Aussagen über die Dynamik der Beschäftigungsentwicklung treffen zu können. Insgesamt1 weist die Region Hannover zwischen 1999 und 2006 ein Nettobeschäftigungswachstum von 2,2 Prozent auf, was mit Blick auf die Vergleichsregionen als relativ ungünstig einzuschätzen ist. Zieht man die Bruttoströme zur Betrachtung hinzu, wird deutlich, dass hinter der relativ geringen Nettowachstumsrate eine beachtliche Dynamik an Beschäftigungsauf- und -abbau steht. So weist die Region Hannover eine Bruttowachstumsrate der Beschäftigung von 35,1 Prozent sowie eine Bruttoabbaurate der Beschäftigung von -32,9 Prozent auf. Im Vergleich zu den anderen Verdichtungsräumen zeigt sich, dass die relativ ungünstige Nettobeschäftigungsentwicklung in der Region Hannover insbesondere auf eine vergleichsweise geringe Bruttowachstumsrate zurückzuführen ist.Region Hannover, Beschäftigungsentwicklung, Paneldaten

Placenta Percreta Presents with Neoangiogenesis of Arteries with Von Willebrand Factor-Negative Endothelium

In placenta percreta cases, large vessels are present on the precrete surface area. As these vessels are not found in normal placentation, we examined their histological structure for features that might explain the pathogenesis of neoangiogenesis induced by placenta accreta spectrum disorders (PAS). In two patients with placenta percreta (FIGO grade 3a) of the anterior uterine wall, one strikingly large vessel of 2 cm length was excised. The samples were formalin fixed and paraffin-embedded. Gomori trichrome staining was used to evaluate the muscular layers and Weigert-Van Gieson staining for elastic fibers. Immunohistochemical staining of the vessel endothelium was performed for Von Willebrand factor (VWF), platelet endothelial cell adhesion molecule (CD31), Ephrin B2, and EPH receptor B4. The structure of the vessel walls appeared artery-like. The vessel of patient one further exhibited an unorderly muscular layer and a lack of elastic laminae, whereas these features appeared normal in the vessel of the other patient. The endothelium of both vessels stained VWF-negative and CD31-positive. In conclusion, this study showed VWF-negative vessel endothelia of epiplacental arteries in placenta accreta spectrum. VWF is known to regulate artery formation, as the absence of VWF has been shown to cause enhanced vascularization. Therefore, we suppose that PAS provokes increased vascularization through suppression of VWF. This process might be associated with the immature vessel architecture as found in one of the vessels and Ephrin B2 and EPH receptor B4 negativity of both artery-like vessels. The underlying pathomechanism needs to be evaluated in a greater set of patients

Data Partitions, Bayesian Analysis and Phylogeny of the Zygomycetous Fungal Family Mortierellaceae, Inferred from Nuclear Ribosomal DNA Sequences

Although the fungal order Mortierellales constitutes one of the largest classical groups of Zygomycota, its phylogeny is poorly understood and no modern taxonomic revision is currently available. In the present study, 90 type and reference strains were used to infer a comprehensive phylogeny of Mortierellales from the sequence data of the complete ITS region and the LSU and SSU genes with a special attention to the monophyly of the genus Mortierella. Out of 15 alternative partitioning strategies compared on the basis of Bayes factors, the one with the highest number of partitions was found optimal (with mixture models yielding the best likelihood and tree length values), implying a higher complexity of evolutionary patterns in the ribosomal genes than generally recognized. Modeling the ITS1, 5.8S, and ITS2, loci separately improved model fit significantly as compared to treating all as one and the same partition. Further, within-partition mixture models suggests that not only the SSU, LSU and ITS regions evolve under qualitatively and/or quantitatively different constraints, but that significant heterogeneity can be found within these loci also. The phylogenetic analysis indicated that the genus Mortierella is paraphyletic with respect to the genera Dissophora, Gamsiella and Lobosporangium and the resulting phylogeny contradict previous, morphology-based sectional classification of Mortierella. Based on tree structure and phenotypic traits, we recognize 12 major clades, for which we attempt to summarize phenotypic similarities. M. longicollis is closely related to the outgroup taxon Rhizopus oryzae, suggesting that it belongs to the Mucorales. Our results demonstrate that traits used in previous classifications of the Mortierellales are highly homoplastic and that the Mortierellales is in a need of a reclassification, where new, phylogenetically informative phenotypic traits should be identified, with molecular phylogenies playing a decisive role

Electrochemical Reduction and Oxidation of Ruddlesden–Popper-Type La2_{2}NiO3_{3}F2_{2} within Fluoride-Ion Batteries

Within this article, it is shown that an electrochemical defluorination and additional fluorination of Ruddlesden–Popper-type La$_2$NiO$_3$F$_2$ is possible within all-solid-state fluoride-ion batteries. Structural changes within the reduced and oxidized phases have been examined by X-ray diffraction studies at different states of charging and discharging. The synthesis of the oxidized phase La$_2$NiO$_3$F$_{2+x}$ proved to be successful by structural analysis using both X-ray powder diffraction and automated electron diffraction tomography techniques. The structural reversibility on re-fluorinating and re-defluorinating is also demonstrated. Moreover, the influence of different sequences of consecutive reduction and oxidation steps on the formed phases has been investigated. The observed structural changes have been compared to changes in phases obtained via other topochemical modification approaches such as hydride-based reduction and oxidative fluorination using F$_2$ gas, highlighting the potential of such electrochemical reactions as alternative synthesis routes. Furthermore, the electrochemical routes represent safe and controllable synthesis approaches for novel phases, which cannot be synthesized via other topochemical methods. Additionally, side reactions, occurring alongside the desired electrochemical reactions, have been addressed and the cycling performance has been studied

White matter microstructural changes in adolescent anorexia nervosa including an exploratory longitudinal study

AbstractBackgroundAnorexia nervosa (AN) often begins in adolescence, however, the understanding of the underlying pathophysiology at this developmentally important age is scarce, impeding early interventions. We used diffusion tensor imaging (DTI) to investigate microstructural white matter (WM) brain changes including an experimental longitudinal follow-up.MethodsWe acquired whole brain diffusion-weighted brain scans of 22 adolescent female hospitalized patients with AN at admission and nine patients longitudinally at discharge after weight rehabilitation. Patients (10–18years) were compared to 21 typically developing controls (TD). Tract-based spatial statistics (TBSS) were applied to compare fractional anisotropy (FA) across groups and time points. Associations between average FA values of the global WM skeleton and weight as well as illness duration parameters were analyzed by multiple linear regression.ResultsWe observed increased FA in bilateral frontal, parietal and temporal areas in AN patients at admission compared to TD. Higher FA of the global WM skeleton at admission was associated with faster weight loss prior to admission. Exploratory longitudinal analysis showed this FA increase to be partially normalized after weight rehabilitation.ConclusionsOur findings reveal a markedly different pattern of WM microstructural changes in adolescent AN compared to most previous results in adult AN. This could signify a different susceptibility and reaction to semi-starvation in the still developing brain of adolescents or a time-dependent pathomechanism differing with extend of chronicity. Higher FA at admission in adolescents with AN could point to WM fibers being packed together more closely

Implementation of a National Reference Laboratory for Buruli Ulcer Disease in Togo

Background: In a previous study PCR analysis of clinical samples from suspected cases of Buruli ulcer disease (BUD) from Togo and external quality assurance (EQA) for local microscopy were conducted at an external reference laboratory in Germany. The relatively poor performance of local microscopy as well as effort and time associated with shipment of PCR samples necessitated the implementation of stringent EQA measures and availability of local laboratory capacity. This study describes the approach to implementation of a national BUD reference laboratory in Togo. Methodology: Large scale outreach activities accompanied by regular training programs for health care professionals were conducted in the regions "Maritime'' and "Central,'' standard operating procedures defined all processes in participating laboratories (regional, national and external reference laboratories) as well as the interaction between laboratories and partners in the field. Microscopy was conducted at regional level and slides were subjected to EQA at national and external reference laboratories. For PCR analysis, sample pairs were collected and subjected to a dry-reagent-based IS2404-PCR (DRB-PCR) at national level and standard IS2404 PCR followed by IS2404 qPCR analysis of negative samples at the external reference laboratory. Principal Findings: The inter-laboratory concordance rates for microscopy ranged from 89% to 94%; overall, microscopy confirmed 50% of all suspected BUD cases. The inter-laboratory concordance rate for PCR was 96% with an overall PCR case confirmation rate of 78%. Compared to a previous study, the rate of BUD patients with non-ulcerative lesions increased from 37% to 50%, the mean duration of disease before clinical diagnosis decreased significantly from 182.6 to 82.1 days among patients with ulcerative lesions, and the percentage of category III lesions decreased from 30.3% to 19.2%. Conclusions: High inter-laboratory concordance rates as well as case confirmation rates of 50% (microscopy), 71% (PCR at national level), and 78% (including qPCR confirmation at external reference laboratory) suggest high standards of BUD diagnostics. The increase of non-ulcerative lesions, as well as the decrease in diagnostic delay and category III lesions, prove the effect of comprehensive EQA and training measures involving also procedures outside the laboratory

SmallSat Solar Axion and Activity X-ray Imager (SSAXI)

Axions are a promising dark matter candidate as well as a solution to the strong charge-parity (CP) problem in quantum chromodynamics (QCD). We describe a new mission concept for SmallSat Solar Axion and Activity X-ray Imager (SSAXI) to search for solar axions or axion-like particles (ALPs) and to monitor solar activity of the entire solar disc over a wide dynamic range. SSAXI aims to unambiguously identify X-rays converted from axions in the solar magnetic field along the line of sight to the solar core, effectively imaging the solar core. SSAXI also plans to establish a statistical database of X-ray activities from Active Regions, microflares, and Quiet Sun regions to understand the origin of the solar corona heating processes. SSAXI employs Miniature lightweight Wolter-I focusing X-ray optics (MiXO) and monolithic CMOS X-ray sensors in a compact package. The wide energy range (0.5 - 6 keV) of SSAXI can easily distinguish spectra of axion-converted X-rays from typical X-ray spectra of solar activities, while encompassing the prime energy band (3 - 4.5 keV) of axion-converted X-rays. The high angular resolution (30 arcsec HPD) and large field of view (40 arcmin) in SSAXI will easily resolve the enhanced X-ray flux over the 3 arcmin wide solar core while fully covering the X-ray activity over the entire solar disc. The fast readout in the inherently radiation tolerant CMOS X-ray sensors enables high resolution spectroscopy with a wide dynamic range in a broad range of operational temperatures. SSAXI will operate in a Sun-synchronous orbit for 1 yr preferably near a solar minimum to accumulate sufficient X-ray photon statistics.Comment: 12 pages, 9 figures, 1 table, Presented at the SPIE Optics + Photonics Conference, August 2019, San Diego, C