CLINICAL STUDY TO EVALUATE THE EFFICACY OF YOGIC SHUDDHIKRIYA (CLEANSING PROCEDURE) AND MADHUDAK (HONEY AND WATER) IN THE MANAGEMENT OF STHAULYA (OBESITY)

Life in today’s materialistic era, has become miserable. As a matter of fact, human life is becoming luxury oriented day by day despite all the odds. According to ecological approach, disease is nothing but a mal-adjustment of human being to his environment. The disruption in environment brings about lifestyle disorders. The sedentary lifestyle of today’s era leads to the non-communicable epidemic of Obesity. Hence for the management of Obesity the therapy which offers modification in the lifestyle will be selected from Yogic Shat-shuddhikriyas i.e. Kapalbhati in comparison with dietary therapy of Madhudak (Honey and Water) as mentioned by Ayurvedic sages. In the present study, 60 patients with features of obesity as per Ayurvedic classics and body mass index more than 25 kg/m2 were selected. This patients will be randomly divided into experimental and control group, containing thirty subjects in each. In experimental group patients were made to perform Kapalbhati yogic shuddhikriya daily at morning whereas in comparison for control group dietary therapy of Madhudak. The study reveals that there was a remarkable decrease in subjective and objective parameters in both the groups, but Kapalbhati therapy is found more effective in every aspects of obesity. Average percentage of relief in experimental group is 27.85% and in control group is 9.93%. Hence to prevent this smoldering problem of present era the ‘Sciences of life’ i.e. Yoga offers the lifestyle modifying, time effective, free of cost, objective therapy (Adravyabhoot chikitsa) through its basic principles

Synthesis and Electrochemical Performance of Mesoporous NiMn2O4 Nanoparticles as an Anode for Lithium-Ion Battery

NiMn2O4 (NMO) is a good alternative anode material for lithium-ion battery (LIB) application, due to its superior electrochemical activity. Current research shows that synthesis of NMO via citric acid-based combustion method envisaged application in the LIB, due to its good reversibility and rate performance. Phase purity and crystallinity of the material is controlled by calcination at different temperatures, and its structural properties are investigated by X-ray diffraction (XRD). Composition and oxidation state of NMO are further investigated by X-ray photoelectron spectroscopy (XPS). For LIB application, lithiation delithiation potential and phase transformation of NMO are studied by cyclic voltammetry curve. As an anode material, initially, the average discharge capacity delivered by NMO is 983 mA center dot h/g at 0.1 A/g. In addition, the NMO electrode delivers an average discharge capacity of 223 mA center dot h/g after cell cycled at various current densities up to 10 A/g. These results show the potential applications of NMO electrodes for LIBs

Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study

Background Results from retrospective studies suggest that use of neuromuscular blocking agents during general anaesthesia might be linked to postoperative pulmonary complications. We therefore aimed to assess whether the use of neuromuscular blocking agents is associated with postoperative pulmonary complications. Methods We did a multicentre, prospective observational cohort study. Patients were recruited from 211 hospitals in 28 European countries. We included patients (aged ≥18 years) who received general anaesthesia for any in-hospital procedure except cardiac surgery. Patient characteristics, surgical and anaesthetic details, and chart review at discharge were prospectively collected over 2 weeks. Additionally, each patient underwent postoperative physical examination within 3 days of surgery to check for adverse pulmonary events. The study outcome was the incidence of postoperative pulmonary complications from the end of surgery up to postoperative day 28. Logistic regression analyses were adjusted for surgical factors and patients’ preoperative physical status, providing adjusted odds ratios (ORadj) and adjusted absolute risk reduction (ARRadj). This study is registered with ClinicalTrials.gov, number NCT01865513. Findings Between June 16, 2014, and April 29, 2015, data from 22803 patients were collected. The use of neuromuscular blocking agents was associated with an increased incidence of postoperative pulmonary complications in patients who had undergone general anaesthesia (1658 [7·6%] of 21694); ORadj 1·86, 95% CI 1·53–2·26; ARRadj –4·4%, 95% CI –5·5 to –3·2). Only 2·3% of high-risk surgical patients and those with adverse respiratory profiles were anaesthetised without neuromuscular blocking agents. The use of neuromuscular monitoring (ORadj 1·31, 95% CI 1·15–1·49; ARRadj –2·6%, 95% CI –3·9 to –1·4) and the administration of reversal agents (1·23, 1·07–1·41; –1·9%, –3·2 to –0·7) were not associated with a decreased risk of postoperative pulmonary complications. Neither the choice of sugammadex instead of neostigmine for reversal (ORadj 1·03, 95% CI 0·85–1·25; ARRadj –0·3%, 95% CI –2·4 to 1·5) nor extubation at a train-of-four ratio of 0·9 or more (1·03, 0·82–1·31; –0·4%, –3·5 to 2·2) was associated with better pulmonary outcomes. Interpretation We showed that the use of neuromuscular blocking drugs in general anaesthesia is associated with an increased risk of postoperative pulmonary complications. Anaesthetists must balance the potential benefits of neuromuscular blockade against the increased risk of postoperative pulmonary complications