151 research outputs found

    Application of value analysis for integral and objective evaluation of university lecturers

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    La feina dels professors a la universitat s'avalua en àmbits molt diversos: docència, investigació, compromís amb la universitat, etc. La majoria de vegades aquesta avaluació es fa de forma segregada, malgrat que forma part integrada de l'activitat del professor amb evidents interaccions entre les seves parts. És per això que és molt útil tenir una metodologia d'avaluació que consideri els múltiples criteris de forma conjunta. L'objectiu d'aquest article és aplicar la metodologia del model integrat de valor per a avaluacions sostenibles (MIVES) per a la selecció de candidats en una habilitació a càtedra. Mitjançant MIVES, es pretén tenir en compte de forma integrada els diferents aspectes que conformen l'activitat ordinària d'un professor, tant en l'entorn intern de la mateixa universitat, com en l'extern, tant si és professional, acadèmic com social. El sistema MIVES planteja una estructura integral per a l'avaluació, utilitza funcions de valor per a l'homogeneïtzació de les unitats de cada un dels criteris definits i aplica un procés d'anàlisi jeràrquica de comparació entre iguals per a l'obtenció dels pesos relatius. MIVES es va aplicar en una primera habilitació a càtedra amb unes deduccions concordants amb els resultats de les proves. En l'article s'exposa aquesta metodologia aplicada en un segon procés d'habilitació l'objectiu del qual era verificar si el model funcionava en una altra àrea de coneixement. Els resultats obtinguts van tornar a ser consistents amb els resultats reals de les proves.El trabajo de los profesores en la universidad se evalúa en ámbitos muy diversos: docencia, investigación, compromiso con la universidad, etc. En la mayoría de las ocasiones esta evaluación se hace de forma segregada, a pesar de formar parte integrada de la actividad del profesor con evidentes interacciones entre sus partes. Por ello, es muy útil disponer de una metodología de evaluación que considere los múltiples criterios de forma conjunta. El objetivo de este artículo es aplicar la metodología del modelo integrado de valor para evaluaciones sostenibles (MIVES) para la selección de candidatos en una habilitación a cátedra. Mediante MIVES se pretende tener en cuenta de forma integrada los diferentes aspectos que conforman la actividad ordinaria de un profesor, tanto en el entorno interno de la propia universidad, como en el externo, ya sea profesional, académico o social. El sistema MIVES plantea una estructura integral para la evaluación, utiliza funciones de valor para la homogeneización de las unidades de cada uno de los criterios definidos y aplica un proceso de análisis jerárquico de comparación por pares para la obtención de los pesos relativos. MIVES fue aplicado en una primera habilitación a cátedra con unas deducciones concordantes con los resultados de dichas pruebas. En este artículo se expone esta metodología aplicada en un segundo proceso de habilitación cuyo objetivo era verificar si el modelo funcionaba en otra área de conocimiento. Los resultados obtenidos volvieron a ser consistentes con los resultados reales de dichas pruebas.The work of university lecturers is evaluated in very diverse areas: teaching, research, commitment to the university, etc. In most cases, each area is evaluated separately, even though they form part of the entirety of the lecturers' activities and obviously interact. For this reason, it is very useful to have an evaluation methodology which takes into consideration all the criteria as a whole. The aim of this article is to apply the MIVES model (integrated methodology of value for sustainable evaluation) for the selection of candidates for professorship. The aim of MIVES is to take into account all the different aspects involved in the normal activity of a lecturer, within the environment of the university itself as well as externally, in professional, academic and social areas. The MIVES system puts forward an integral structure for evaluation, using value functions to standardise the units of each of the defined criteria, and applying a system of peer comparison to assign a relative weight to each criterium. MIVES has been applied to qualify a lectureship with conclusions in agreement with the results of the aforementioned evaluated areas. This article discusses this methodology applied to a second process of qualification whose aim was to verify whether the model functions in another area of knowledge. The results obtained were consistent with those of the aforementioned evaluations

    Accelerating time series motif discovery in the Intel Xeon Phi KNL processor

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    Presented at HiPEAC Conference 2020, Bologna (Italy)Time series analysis is an important research topic of great interest in many fields. However, the memory-bound nature of the state-of-the-art algorithms limits the execution performance in some processor architectures. We analyze the Matrix Profile algorithm from the performance viewpoint in the context of the Intel Xeon Phi Knights Landing architecture (KNL). The experimental evaluation shows a performance improvement up to 190x with respect to the sequential execution and that the use of the HBM memory improves performance in a factor up to 5x with respect to the DDR4 memory.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Cosmeceutical Potential of Major Tropical and Subtropical Fruit By-Products for a Sustainable Revalorization

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    The work was supported by the project P18-TP-3589 (Regional Ministry of Economy, Knowledge, Enterprise and Universities of Andalusia). The author A.R.-G. would like to thank the project P18-TP-3589, University of Granada and AGR274 group for the contract (265).The author A.G.-V. would like to thank the Spanish National Youth Guarantee Implementation Plan for her contract. The author M.d.C.V.-A. would like to thank the Spanish Ministry of Science,Innovation, and Universities for the grant FPU19/01146. The author M.d.l.L.C.-G. would like to thank the Regional Ministry of Economy, Knowledge, Enterprise and Universities of Andalusia for the contract for Young Researchers (PAIDI) at the University of Granada.The increasing production of tropical fruits followed by their processing results in tons of waste, such as skins or seeds. However, these by-products have been reported to be rich in bioactive compounds (BACs) with excellent properties of interest in the cosmeceutical industry: antioxidant, anti-aging, anti-inflammatory, antimicrobial and photoprotective properties. This review summarizes the tropical fruits most produced worldwide, their bioactive composition and the most important and studied therapeutic properties that their by-products can contribute to skin health, as well as the different approaches for obtaining these compounds using techniques by conventional (Soxhlet, liquid-liquid extraction or maceration) and non-conventional extractions (supercritical fluid extraction (SFE), ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), pressurized liquid extraction (PLE) and two-phase aqueous system), followed by their identification by HPLC-MS or GC-MS analysis. Moreover, this work encompasses several studies that may prove the effects of seeds and skins from tropical fruits against oxidative stress, hyperpigmentation, acne, aging or UV radiation. Therefore, the investigation of functional components present in tropical fruit by-products under a circular bioeconomy model could be of great interest for the cosmeceutical industry and a very promising option for obtaining new cosmeceutical formulations.Regional Ministry of Economy, Knowledge, Enterprise and Universities of Andalusia P18-TP-3589Spanish National Youth Guarantee Implementation Plan P18-TP-3589University of Granada AGR274 group 265Spanish National Youth Guarantee Implementation PlanSpanish Government FPU19/01146 AGR27

    Valorisation of Olea europaea L. Olive Leaves through the Evaluation of Their Extracts: Antioxidant and Antimicrobial Activity

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    Olea europaea L. leaves constitute a source of bioactive compounds with recognized benefits for both human health and technological purposes. In the present work, different extracts from olive leaves were obtained by the application of two extraction methods, Soxhlet and microwave-assisted extraction (MAE), and six solvents (distilled water, ethanolic and glycerol mixtures solvents). MAE was applied under 40, 60 and 80 °C for 3, 6.5 and 10 min. The effect of the extraction method, solvent and treatment factors (the latter in MAE) on the total phenol content (TPC), the antioxidant activity (AA) and the phenolic profile of the extracts were all evaluated. The extracts showed high values of TPC (up to 76.1 mg GAE/g DW) and AA (up to 78 mg TE/g DW), with oleuropein being the most predominant compound in all extracts. The Soxhlet extraction method exhibited better yields in TPC than in MAE, although both methods presented comparable AA values. The water MAE extract presented the strongest antimicrobial activity against five foodborne pathogens, with minimum inhibitory concentration (MIC) values ranging from 2.5 to 60 mg/mL. MAE water extract is proposed to be exploited in the food and nutraceutical industry in the frame of a sustainable economy

    PCA-based Multivariate Statistical Network Monitoring for Anomaly Detection

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    The multivariate approach based on Principal Component Analysis (PCA) for anomaly detection received a lot of attention from the networking community one decade ago mainly thanks to the work of Lakhina and co-workers. However, this work was criticized by several authors that claimed a number of limitations of the approach. Neither the original proposal nor the critic publications were completely aware of the established methodology for PCA anomaly detection, which by that time had been developed for more than three decades in the area of industrial monitoring and chemometrics as part of the Multivariate Statistical Process Control (MSPC) theory. In this paper, the main steps of the MSPC approach based on PCA are introduced; related networking literature is reviewed, highlighting some differences with MSPC and drawbacks in their approaches; and specificities and challenges in the application of MSPC to networking are analyzed. All of this is demonstrated through illustrative experimentation that supports our discussion and reasoning

    Aceleración del análisis de series temporales en el procesador Intel Xeon Phi KNL

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    El análisis de series temporales es un campo de investigación de gran interés con innumerables aplicaciones. Recientemente, el método Matrix Profile, y particularmente una de sus implementacio nes, el algoritmo SCRIMP, ha empezado a cobrar relevancia en este campo. En este trabajo analizamos la estructura y el ren dimiento del algoritmo SCRIMP en el contexto de una arquitectura Intel Xeon Phi Knights Landing (KNL), que integra módulos de memoria HBM (High-Bandwidth Memory). En este análisis combinamos diferentes técnicas para explotar el potencial de la arquitectura. Por un lado, explotamos la capacidad multihilo y vectorial de la arquitectura. Por otro lado, exploramos cómo ubicar los datos en la memoria para extraer el máximo rendimiento de la arquitectura de memoria hı́brida disponible, haciendo uso tanto de la memoria 3D de alto ancho de banda como de la memoria convencional DRAM DDR4.Sociedad de Arquitectura y Tecnología de Computadores (SARTECO) Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    The Potential of Mangifera indica L. Peel Extract to Be Revalued in Cosmetic Applications

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    This research was funded by the Regional Ministry of Economy, Knowledge, Enterprise, and Universities of Andalusia grant number P18-TP-3589. The author A.G.-V. expresses gratitude to the project P18-TP-3589, as well as to the University of Granada and AGR274 group for her contract. Á.F.-O. would like to thank the Regional Ministry of Economy, Knowledge, Enterprise and Universities of Andalusia for the contract for Young Researchers (PAIDI) at the University of Granada. A.R.-G. would like to thank the Spanish Ministry of Science, Innovation, and Universities for the grant FPU21/02714. M.d.l.L.C.-G. thanks her contract RYC2021-032119-I founded by MCIN/AEI/10.13039/501100011033 and NextGenerationEU/PRTR. The authors are also grateful to the Company “Grupo Empresarial La Caña” for ensuring traceability assurance of the samples and for its commitment to the research group and I+D+i.The constant growth of the cosmetic industry, together with the scientific evidence of the beneficial properties of phytochemicals, has generated great interest in the incorporation of bioactive extracts in cosmetic formulations. This study aims to evaluate the bioactive potential of a mango peel extract for its incorporation into cosmetic formulations. For this purpose, several assays were conducted: phytochemical characterization; total phenolic content (TPC) and antioxidant potential; free-radical scavenging capacity; and skin aging-related enzyme inhibition. In addition, the extract was incorporated into a gel formulation, and a preliminary stability study was conducted where the accelerated (temperature ramp, centrifugation, and heating/cooling cycles) and long-term (storage in light and dark for three months) stability of the mango peel formulations were evaluated. The characterization results showed the annotation of 71 compounds, gallotannins being the most representative group. In addition, the mango peel extract was shown to be effective against the center dot NO radical with an IC50 of 7.5 mg/L and against the hyaluronidase and xanthine oxidase enzymes with IC50 of 27 mg/L and 2 mg/L, respectively. The formulations incorporating the extract were stable during the stability study. The results demonstrate that mango peel extract can be a by-product to be revalorized as a promising cosmetic ingredient.University of GranadaAGR274Spanish Ministry of Science, Innovation, and Universities FPU21/02714MCIN/AEI/10.13039/501100011033NextGenerationEU/PRTR RYC2021-032119-IRegional Ministry of Economy, Knowledge, Enterprise, and Universities of Andalusia grant number P18-TP-358

    Aplicación del análisis de valor para una evaluación integral y objetiva del profesorado universitario

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    El trabajo de los profesores en la universidad se evalúa en ámbitos muy diversos: docencia, investigación, compromiso con la universidad, etc. En la mayoría de las ocasiones esta evaluación se hace de forma segregada, a pesar de formar parte integrada de la actividad del profesor con evidentes interacciones entre sus partes. Por ello, es muy útil disponer de una metodología de evaluación que considere los múltiples criterios de forma conjunta. El objetivo de este artículo es aplicar la metodología del modelo integrado de valor para evaluaciones sostenibles (MIVES) para la selección de candidatos en una habilitación a cátedra. Mediante MIVES se pretende tener en cuenta de forma integrada los diferentes aspectos que conforman la actividad ordinaria de un profesor, tanto en el entorno interno de la propia universidad, como en el externo, ya sea profesional, académico o social. El sistema MIVES plantea una estructura integral para la evaluación, utiliza funciones de valor para la homogeneización de las unidades de cada uno de los criterios definidos y aplica un proceso de análisis jerárquico de comparación por pares para la obtención de los pesos relativos. MIVES fue aplicado en una primera habilitación a cátedra con unas deducciones concordantes con los resultados de dichas pruebas. En este artículo se expone esta metodología aplicada en un segundo proceso de habilitación cuyo objetivo era verificar si el modelo funcionaba en otra área de conocimiento. Los resultados obtenidos volvieron a ser consistentes con los resultados reales de dichas pruebas.Peer ReviewedPostprint (published version

    Characterization of the antimicrobial activity of a clone with metagenomic DNA from a refinery.

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    Motivation: The increase in the number of antibiotic resistance mechanisms in microorganisms added to the low rate of newantimicrobial (AM) development supposes a threat for public health that should be urgently approached. Bacteria are one ofthe biggest sources of AM but only a small fraction of them can be cultured in vitro. To overcome this limitation our lab uses afunctional metagenomic approach and had previously developed a heterologous expression system that allows the study of allthe gene pool from a specific environmen1,2. Using this strategy we found different clones whose metagenomic DNA expresssion produces AM activity against Micrococcus luteus and also against the Methicillin-resistant Staphylococcus aureus (MRSA), one of the World Health Organization’s main priorities regarding resistant bacteria. In this work we study the properties and the activity of the AM produced by three different subclones with homologous genes related to phenol metabolism that were found in two different metagenomic libraries and we further characterize one of these subclones, pMPO1718, which proceeds from a refinery metagenomic library.Methods: The AM is produced in liquid cultures, the antimicrobial production is increased with arabinose for 6-7h and thenthe supernatant is filtered and lyophilized. The AM activity is tested on LB soft agar plates inoculated with the target strains.The AM is separated in different fractions by chromatography to study in which of them the activity is present.Results: We have defined a protocol to produce the AM in minimum media complemented with tryptophan and we haveobserved AM activity against M.luteus in the filtered culture and even higher activity in the total culture extracted with acetone50%. The last one was analyzed by high performance liquid chromatography and mass spectrometry by Fundación MEDINAand the comparison with databases showed that it may be an AM not previously described. Some AM properties arecharacterized in this work such as the minimum inhibitory concentration, the minimum bactericidal concentration, itsthermostability, its activity in different solvents or against different bacteria.Conclusions: The filtered supernatant of the three different subclones has AM activity against M.luteus and MRSA producedby phenol hydroxylase related genes. This AM is thermostable until more than 100ºC, has bactericidal activity and can beproduced either in LB medium or in M9 medium complemented with tryptophan

    Factors associated with interest in scientific research in dental students of six Cuban universities

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    "Introduction: To determine the factors associated with interest in scientific research in dental students of six Cuban universities. Methods: This is a multicenter cross-sectional analytical study. Interest in scientific research was the dependent variable, and it was assessed through a questionnaire proved to be reliable (Cronbach’s α= 0.88). We obtained adjusted prevalence ratios (aPR), 95% confidence intervals (95% CI), and p values through generalized linear models. Results: A total of 587 students were part of the research, and 57.9% manifested interest in scientific research. However, when they were asked if they wanted to pursue a research career in the future, only 45.1% responded affirmatively. We found, through multivariate analysis, that there was more interest in scientific research among those who were student assistants (aPR: 2.42; 95% CI: 1.41–4.16; p = 0.001), those who had previous studies (aPR: 1.35; 95% CI: 1.02–1.79; p = 0.034), and those who had received awards in scientific events (aPR: 1.74; 95% CI: 1.26–2.41; p = 0.001). In contrast, there was less interest among those who were at the clinical stage of their career (aPR: 0.66; 95% CI: 0.49–0.89; p = 0.006), adjusted for seven variables. Conclusions: There exists interest in scientific research and we found some factors associated with this. This has to be taken into account in order for educational institutions to generate strategies.
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