906 research outputs found

    Landings and discards on the pulse trawl MFV "Vertrouwen"TX68 in 2009

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    The catches in terms of landings and discards were monitored onboard MFV “Vertrouwen” TX68, fishing with two pulse trawls using the Verburg-Holland system during four weeks in June-August 2009. The average fishing speed was about 5 knots. The fishing area of the four trips was east of the coast of England and fishing depth was 36m on average with a minimum depth of 20 m and a maximum depth of 46 m. For this study the standard sampling procedure for the yearly monitoring of discards of conventional beam trawl fleet was applied (van Helmond and van Overzee, 2008). Sampled numbers of fish per haul were raised to numbers and weight per hour, for both. When compared with conventional beam trawls in previous years it seems that with the pulse trawl more sole in number and weights per unit of time was discarded and less plaice was discarded. However, the average discard percentages of as well plaice as sole for the pulse trawl of this study were within range with the average discard percentages of conventional beam trawls in 2005, 2006 and 2007 (van Keeken, 2006; van Helmond and van Overzee, 2007; van Helmond and van Overzee, 2008) . This study gives a general impression of the performance in terms of catches of fishing with a pulse trawl using the Verburg-Holland system. However it is recommended to conduct a comparative study on performance of a beam trawl and a pulse trawl, where the two vessels of similar size fish simultaneously, like was done in 2006 by van Marlen et al. This is to exclude the effects of time and area of fishing

    Attentional processes of high-skilled soccer players with congenital hemiparesis: Differences related to the side of the hemispheric lesion

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    Contains fulltext : 72909.pdf (publisher's version ) (Closed access)We investigated attentional processes that support the performance of high-skilled soccer players with hemiparetic cerebral palsy. Participants (N = 10) dribbled a slalom course as quickly and accurately as possible under two attentional-focus manipulation conditions. In the task-relevant focus condition, they attended to the foot that was in contact with the ball, whereas in the task-irrelevant focus condition, they monitored a series of words played on a tape. The time taken to complete the slalom course was registered. Performances of individuals with left and right hemiparesis were compared to explore differential effects of hemispheric lesion. The high-skilled players with congenital hemiparesis showed similar attentional-focus effects as those previously reported in the literature for high-skilled players without neurological disorders (Beilock et al., 2002; Ford et al., 2005). Task-relevant focus increased dribbling time, whereas a task-irrelevant focus did not result in a significant change in dribbling time. These findings generalized to each of the five participants with left hemiparesis (i.e., damage to the right hemisphere). By contrast, the effects of a task-relevant focus were less consistent for participants with right hemiparesis (i.e., left-hemisphere damage). This corroborates suggestions that the reinvestment of procedural knowledge is a left-lateralized function. The implications for the training of individuals with congenital brain damage are discussed

    Eye–hand coordination during manual object transport with the affected and less affected hand in adolescents with hemiparetic cerebral palsy

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    In the present study we investigated eye–hand coordination in adolescents with hemiparetic cerebral palsy (CP) and neurologically healthy controls. Using an object prehension and transport task, we addressed two hypotheses, motivated by the question whether early brain damage and the ensuing limitations of motor activity lead to general and/or effector-specific effects in visuomotor control of manual actions. We hypothesized that individuals with hemiparetic CP would more closely visually monitor actions with their affected hand, compared to both their less affected hand and to control participants without a sensorimotor impairment. A second, more speculative hypothesis was that, in relation to previously established deficits in prospective action control in individuals with hemiparetic CP, gaze patterns might be less anticipatory in general, also during actions performed with the less affected hand. Analysis of the gaze and hand movement data revealed the increased visual monitoring of participants with CP when using their affected hand at the beginning as well as during object transport. In contrast, no general deficit in anticipatory gaze control in the participants with hemiparetic CP could be observed. Collectively, these findings are the first to directly show that individuals with hemiparetic CP adapt eye–hand coordination to the specific constraints of the moving limb, presumably to compensate for sensorimotor deficits

    Disentangling heterogeneity in contemporary undifferentiated arthritis – A large cohort study using latent class analysis

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    Objectives: Undifferentiated arthritis(UA) is clinically heterogeneous and differs in outcomes ranging from spontaneous resolution to RA-development. Therefore, we hypothesized that subgroups exist within UA and we aimed to identify homogeneous groups based on clinical features, and thereafter to relate these groups to the outcomes spontaneous resolution and RA-development. These outcomes can only be studied in UA-patients in which DMARD-treatment does not influence the natural disease course; these cohorts are scarce. Methods: We studied autoantibody-negative UA-patients (not fulfilling 1987/2010 RA-criteria, no alternate diagnosis), included in the Leiden Early Arthritis Clinic between 1993 and 2006, when early DMARD-treatment in UA was infrequent. Latent class analysis was used to identify subgroups based on combinations of clinical features. Within these subgroups, test-characteristics were assessed for spontaneous resolution of arthritis and RA-development within 1 year. Results: 310 consecutive UA-patients were studied. Five classes were identified: location and number of swollen joints were most distinguishing. Classes were characterized by: 1) polyarthritis, often symmetric; 2) oligoarthritis, frequently with subacute onset; 3) wrist-monoarthritis, often with subacute onset, increased BMI and without morning stiffness; 4) small-joint monoarthritis, often without increased acute phase reactants, and 5) large-joint monoarthritis, often with subacute onset. Studying the classes in relation to the outcomes revealed that patients without spontaneous resolution (thus having persistent disease) were nearly absent in the classes characterized by monoarthritis (specificity &gt;90%). Additionally, patients who developed RA were infrequent in monoarthritis classes (sensitivity &lt;7%). Conclusion: Using a data-driven unsupervised approach, five subgroups within contemporary UA were identified. These have differences in the natural course of disease.</p

    Effectiveness and tolerability of pegylated interferon alfa-2b in combination with ribavirin for treatment of chronic hepatitis C: the PegIntrust Study

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    Background and study aims : Large international clinical trials conducted in the past 5 years rapidly improved the treatment of chronic hepatitis C; however, it is unclear whether the advances seen in clinical trials are being paralleled by similar improvements in routine clinical practice. PegIntrust is a Belgian community-based trial evaluating the sustained virological response. Patients and Methods : Observational study of 219 patients receiving pegylated interferon alfa-2b (1.5 mu g/kg/wk) and weight. based ribavirin (800-1200 mg/day) for 48 weeks. Primary study end point was sustained virological response (SVR), defined as undetectable HCV RNA 6 months after the completion of treatment. Results : In total, 108 patients (49.3 %) had undetectable HCV RNA at the end of therapy, 91(41.6%) attaining SVR. Of the 111 patients without an end-of-treatment response, 28 were non-responders, and 21 had virological breakthrough. In total, 134 patients attained early virological response (EVR); 88 (65.7%) of those patients attained SVR. In contrast, 82 (96.5 %) of the 85 patients who did not attain EVR also did not attain SVR. Age, fibrosis score and baseline viral load were identified as important predictors of treatment outcome. The most frequently reported serious adverse events resulting in treatment discontinuation were anemia (n = 10), fatigue/asthenia/malaise (n = 6) and fever (n = 3). Conclusion : Our data indicate that treatment of chronic hepatitis C with PEG-IFN alfa-2b plus weight-based ribavirin results in favourable treatment outcomes in a Belgian cohort of patients treated in community-based clinical practice. (Ada gastroenterol. belg., 2010, 73, 5-11)
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