Jingmen tick virus : a tick-borne virus with unique features.

非分節化ゲノムのフラビウイルスに分類されながら、分節化したウイルスゲノムを持つingmenvirusは、昆虫及び脊椎動物に感染するアルボウイルスという性質のみならず、ゲノム構造の進化と粒子の多成分性による感染という、ウイルス学上重要な問題に対しても新しい視点を与えてくれるユニークな特徴を持っている。本稿ではJingmenvirusの中でも、このウイルス発見の端緒となったJingmen tick virusを中心にウイルス学的な特徴について解説した。The discovery of Jingmenvirus, which encodes closely related flavivirus-like enzymes but possesses segmented +ssRNA genomes, sparked significant debate regarding the evolutionary pathways leading to the creation of such viruses. This review outlines the distinctive features of Jingmenviruses, with a particular focus on the Jingmen tick virus—an arbovirus transmitted by ticks, posing potential risks as a human infectious agent.departmental bulletin pape

Iatrogenic intramuscular hematoma of the oblique muscles as a complication of technetium-99m-labeled pyrophosphate imaging-based computed tomography-guided core-needle biopsy in a patient with wild-type transthyretin cardiac amyloidosis

Technetium-99m-labeled pyrophosphate imaging-based computed tomography-guided core-needle biopsy of the internal oblique muscle with tracer uptake is a safe and sensitive extracardiac screening biopsy. It can provide histopathological confirmation of the deposition of amyloid transthyretin in patients with wild-type transthyretin cardiac amyloidosis. This case report presents the case of a 73-year-old man receiving triple anti-thrombotic therapy for atrial flutter and coronary stenting who underwent this biopsy to confirm the diagnosis of transthyretin cardiac amyloidosis. The biopsy needle reached the internal oblique muscle via the external oblique muscle between the skin and the target. A type 1 intramuscular hematoma involving these muscles developed subsequently; however, manual compression hemostasis prevented further increase in size. Since this biopsy often targets elderly patients receiving anti-thrombotic therapy who are at high risk of bleeding owing to multimorbidity and polypharmacy, efforts should be made to reduce the frequency of complications, particularly bleeding, which can lead to the development of intramuscular hematoma

ダニ媒介性ウイルスJingmen tick virusが提起するウイルス学上の問題について

非分節化ゲノムのフラビウイルスに分類されながら、分節化したウイルスゲノムを持つingmenvirusは、昆虫及び脊椎動物に感染するアルボウイルスという性質のみならず、ゲノム構造の進化と粒子の多成分性による感染という、ウイルス学上重要な問題に対しても新しい視点を与えてくれるユニークな特徴を持っている。本稿ではJingmenvirusの中でも、このウイルス発見の端緒となったJingmen tick virusを中心にウイルス学的な特徴について解説した。The discovery of Jingmenvirus, which encodes closely related flavivirus-like enzymes but possesses segmented +ssRNA genomes, sparked significant debate regarding the evolutionary pathways leading to the creation of such viruses. This review outlines the distinctive features of Jingmenviruses, with a particular focus on the Jingmen tick virus—an arbovirus transmitted by ticks, posing potential risks as a human infectious agent