21 research outputs found
THE PROGRESSIVEISM OF THE MUCKRAKERS
Photograph of the 2nd floor Ironing Room of Nu-Way Cleaners Dyers Hatters, 811 North Western Avenue, Oklahoma City, OK. Photo by Waterhouse, Oklahoma City, OK, c. 1929-1933
Mammographic density, breast cancer risk and risk prediction
In this review, we examine the evidence for mammographic density as an independent risk factor for breast cancer, describe the risk prediction models that have incorporated density, and discuss the current and future implications of using mammographic density in clinical practice. Mammographic density is a consistent and strong risk factor for breast cancer in several populations and across age at mammogram. Recently, this risk factor has been added to existing breast cancer risk prediction models, increasing the discriminatory accuracy with its inclusion, albeit slightly. With validation, these models may replace the existing Gail model for clinical risk assessment. However, absolute risk estimates resulting from these improved models are still limited in their ability to characterize an individual's probability of developing cancer. Promising new measures of mammographic density, including volumetric density, which can be standardized using full-field digital mammography, will likely result in a stronger risk factor and improve accuracy of risk prediction models
Protein secondary structure analysis of dried blood serum using infrared spectroscopy to identify markers for colitis screening
Branded Radio Program and Awareness of Under-utilized Indigenous Vegetable Innovations in Southwestern Nigeria (Innovation Dissemination through Branded Radio Program)
The Impact of Climate Change on Indigenous Arabica Coffee (Coffea arabica): Predicting Future Trends and Identifying Priorities
Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution
Lampreys are representatives of an ancient vertebrate lineage that diverged from our own ~500 million years ago. By virtue of this deeply shared ancestry, the sea lamprey (P. marinus) genome is uniquely poised to provide insight into the ancestry of vertebrate genomes and the underlying principles of vertebrate biology. Here, we present the first lamprey whole-genome sequence and assembly. We note challenges faced owing to its high content of repetitive elements and GC bases, as well as the absence of broad-scale sequence information from closely related species. Analyses of the assembly indicate that two whole-genome duplications likely occurred before the divergence of ancestral lamprey and gnathostome lineages. Moreover, the results help define key evolutionary events within vertebrate lineages, including the origin of myelin-associated proteins and the development of appendages. The lamprey genome provides an important resource for reconstructing vertebrate origins and the evolutionary events that have shaped the genomes of extant organisms