Re-examination of the Effects of Food Abundance on Jaw Plasticity in Purple Sea Urchins

Morphological plasticity is a critical mechanism that animals use to cope with variations in resource availability. During periods of food scarcity, sea urchins demonstrate an increase in jaw length relative to test diameter. This trait is thought to be reversible and adaptive by yielding an increase in feeding efficiency. We directly test the hypotheses that (1) there are reversible shifts in jaw length to test diameter ratios with food abundance in individual urchins, and (2) these shifts alter feeding efficiency. Purple sea urchins, Strongylocentrotus purpuratus, were collected and placed in either high or low food treatments for 3 months, after which treatments were switched for two additional months between February and September, 2015 in La Jolla, CA (32.8674°N, 117.2530°W). Measurements of jaw length to test diameter ratios were significantly higher in low compared to high food urchins, but this was due to test growth in the high food treatments. Ratios of low food urchins did not change following a switch to high food conditions, indicating that this trait is not reversible within the time frame of this study. Relatively longer jaws were also not correlated with increased feeding efficiency. We argue that jaw length plasticity is not adaptive and is simply a consequence of exposure to high food availability, as both jaw and test growth halt when food is scarce

An analysis of penetration and ricochet phenomena in oblique hypervelocity impact

An experimental investigation of phenomena associated with the oblique hypervelocity impact of spherical projectiles on multisheet aluminum structures is described. A model that can be employed in the design of meteoroid and space debris protection systems for space structures is developed. The model consists of equations that relate crater and perforation damage of a multisheet structure to parameters such as projectile size, impact velocity, and trajectory obliquity. The equations are obtained through a regression analysis of oblique hypervelocity impact test data. This data shows that the response of a multisheet structure to oblique impact is significantly different from its response to normal hypervelocity impact. It was found that obliquely incident projectiles produce ricochet debris that can severely damage panels or instrumentation located on the exterior of a space structure. Obliquity effects of high-speed impact must, therefore, be considered in the design of any structure exposed to the meteoroid and space debris environment

THE INFLUENCE OF TRP53 IN THE DOSE RESPONSE OF RADIATIONINDUCED APOPTOSIS, DNA REPAIR AND GENOMIC STABILITY IN MURINE HAEMATOPOIETIC CELLS

Apoptotic and DNA damage endpoints are frequently used as surrogate markers of cancer risk, and have been well-studied in the Trp53+/- mouse model. We report the effect of differing Trp53 gene status on the dose response of ionizing radiation exposures (0.01- 2 Gy), with the unique perspective of determining if effects of gene status remain at extended time points. Here we report no difference in the dose response for radiationinduced DNA double-strand breaks in bone marrow and genomic instability (MN-RET levels) in peripheral blood, between wild-type (Trp53+/+) and heterozygous (Trp53+/-) mice. The dose response for Trp53+/+ mice showed higher initial levels of radiation-induced lymphocyte apoptosis relative to Trp53+/- between 0 and 1 Gy. Although this trend was observed up to 12 hours post-irradiation, both genotypes ultimately reached the same level of apoptosis at 14 hours, suggesting the importance of late-onset p53-independent apoptotic responses in this mouse model. Expected radiation-induced G1 cell cycle delay was observed in Trp53+/+ but not Trp53+/-. Although p53 has an important role in cancer risk, we have shown its influence on radiation dose response can be temporally variable. This research highlights the importance of caution when using haematopoietic endpoints as surrogates to extrapolate radiation-induced cancer risk estimation

Chandra Observations of the Gamma-ray Binary LSI+61303: Extended X-ray Structure?

We present a 50 ks observation of the gamma-ray binary LSI+61303 carried out with the ACIS-I array aboard the Chandra X-ray Observatory. This is the highest resolution X-ray observation of the source conducted so far. Possible evidence of an extended structure at a distance between 5 and 12 arcsec towards the North of LSI+61303 have been found at a significance level of 3.2 sigma. The asymmetry of the extended emission excludes an interpretation in the context of a dust-scattered halo, suggesting an intrinsic nature. On the other hand, while the obtained source flux, of F_{0.3-10 keV}=7.1^{+1.8}_{-1.4} x 10^{-12} ergs/cm^2/s, and hydrogen column density, N_{H}=0.70+/-0.06 x 10^{22} cm^{-2}, are compatible with previous results, the photon index Gamma=1.25+/-0.09 is the hardest ever found. In light of these new results, we briefly discuss the physics behind the X-ray emission, the location of the emitter, and the possible origin of the extended emission ~0.1 pc away from LSI+61303.Comment: 4 pages, 3 figures. Accepted for publication in ApJ Letter

Innovating Cultural Competence Education for Nurses

Objective To improve cultural competency levels of registered nurses on the Mother/Baby unit by educating nurses. Background Demographics are shifting in the U.S. with an increase in minority populations. Research has revealed insufficient education or a complete absence of education, resulting in nurses that are not equipped to adequately care for culturally diverse patients. Methods The Evidence-Based Practice Improvement (EBPI) Model guided the development and implementation of the project. A cultural competence education module was developed utilizing resources from the U.S. Department of Health and Human Services. Outcomes were measured using a pretest/posttest design tool, the Inventory for Assessing the Process of Cultural Competence Among Healthcare Professionals- Revised (IAPCC-R) to assess cultural competency levels. Results A paired sample t-test was used to determine if there was a significant change between pretest and posttest scores in 14 participants. Scores significantly increased (p=0.002) from 73.57 at pretest to 81.64 at posttest. Items were summed to create subscales scores for awareness, desire, skill, knowledge and encounters. Scores significantly increased for all constructs, though knowledge did not significantly increase. Conclusion Cultural competence education increased the overall cultural competency levels of registered nurses on the Mother/Baby unit. Implication for Nurses Culturally competent education has been associated with improved awareness, desire, skill and encounters, which in turn supports patient-centered care

Experiences of learning through collaborative evaluation from a masters programme in professional education

This paper presents findings from a collaborative evaluation project within a masters programme in professional education. The project aimed to increase knowledge of research methodologies and methods through authentic learning where participants worked in partnership with the tutor to evaluate the module which they were studying. The project processes, areas of the course evaluated and the data collection methods are outlined. The findings focus on key themes from evaluating the effectiveness of using a collaborative evaluation approach, including: enhanced student engagement; creativity of the collaborative evaluation approach; equality between the tutor and students; and enhanced research skills. Discussion focuses on the outcomes and effectiveness of the project and tutor reflections on adopting a collaborative approach. This paper highlights lessons from the project relevant to those interested in staff-student partnership approaches and those facilitating postgraduate learning and teaching programmes and educational research courses

Green's Functions and Non-Singlet Glueballs on Deformed Conifolds

We study the Laplacian on Stenzel spaces (generalized deformed conifolds), which are tangent bundles of spheres endowed with Ricci flat metrics. The (2d-2)-dimensional Stenzel space has SO(d) symmetry and can be embedded in C^d through the equation \sum_{i = 1}^d {z_i^2} = \epsilon^2. We discuss the Green's function with a source at a point on the S^{d-1} zero section of TS^{d-1}. Its calculation is complicated by mixing between different harmonics with the same SO(d) quantum numbers due to the explicit breaking by the \epsilon-deformation of the U(1) symmetry that rotates z_i by a phase. A similar mixing affects the spectrum of normal modes of warped deformed conifolds that appear in gauge/gravity duality. We solve the mixing problem numerically to determine certain bound state spectra in various representations of SO(d) for the d=4 and d=5 examples.Comment: 52 pages, 3 figure

A Detailed Observational Analysis of V1324 Sco, the Most Gamma-Ray Luminous Classical Nova to Date

It has recently been discovered that some, if not all, classical novae emit GeV gamma rays during outburst, but the mechanisms involved in the production of the gamma rays are still not well understood. We present here a comprehensive multi-wavelength dataset---from radio to X-rays---for the most gamma-ray luminous classical nova to-date, V1324 Sco. Using this dataset, we show that V1324 Sco is a canonical dusty Fe-II type nova, with a maximum ejecta velocity of 2600 km s$^{-1}$ and an ejecta mass of few $\times 10^{-5}$ M$_{\odot}$. There is also evidence for complex shock interactions, including a double-peaked radio light curve which shows high brightness temperatures at early times. To explore why V1324~Sco was so gamma-ray luminous, we present a model of the nova ejecta featuring strong internal shocks, and find that higher gamma-ray luminosities result from higher ejecta velocities and/or mass-loss rates. Comparison of V1324~Sco with other gamma-ray detected novae does not show clear signatures of either, and we conclude that a larger sample of similarly well-observed novae is needed to understand the origin and variation of gamma rays in novae.Comment: 26 pages, 13 figure