クロレラのデンプンとオイル蓄積に関する実験室と屋外大量培養による研究

学位の種別: 課程博士審査委員会委員 : （主査）東京大学教授 河野 重行, 東京大学教授 宇垣 正志, 東京大学教授 馳澤 盛一郎, 東京大学教授 大矢 禎一, 京都大学教授 宮下 英明University of Tokyo(東京大学

Diseño de sistema de alcantarillado sanitario y ampliación del sistema de agua potable del Barrio Villa Vallarta en la Ciudad de Managua

El presente estudio monográfico denominado "DISEÑO DEL SISTEMA DE ALCANTARILLADO SANITARIO Y AMPLIACIÓN DEL SISTEMA DE AGUA POTABLE EN EL BARRIO VILLA VALLARTA'', tiene como propósito mejorar las condiciones higiénico-sanitarias de la población, djsminuir el índice de mortalidad infantil y promover cambios de comportamientos en los miembros de las familias beneficiadas, para que mejoren su nivel de vida. EI Barrio Villa Vallarta se encuentra ubicado en la parie Nor-Este de la ciudad de Managua, localizándose en la zona alta del Acueducto de Managua; específicamente está ubicado en el Distrito No. Vl de la municipalidad de Managua. Se caracteriza por ser una zona de alta densidad debido que en dicho Barrio se encuentran construcciones sencillas y lotes con dimensiones y áreas homogéneas, de aproximadamente | 05 m2. Esta conformado por 393 viviendas,13 manzanas, 9 calles y 3 avenidas, alcanzando un área total de aproximadamente 67, 327.81 m2, incluyendo calles, avenidas y un área comunal de 1,575.45 m2 La calles miden aproximadamente 750.45 m2 Para formular el estudio monográfico, primeramente se realizó un diagnóstico situacional a través de ntrevistas y encuesta dirigidas. a funcionarios, líderes comunales y familias del Barrio. Posteriormente se efectuará el estudio topográfico y el estudio de suelo para conocer las características del terreno y la clasificación o tipo de suelo que predomina en el Barrio. Además se realizó la valoración del Sistema de Alcantarillado Sanitario y Sistema de Agua Potable existente

Protocol for a multicentre, prospective observational study of elective neck dissection for clinically node-negative oral tongue squamous cell carcinoma (END-TC study)

Introduction: In early-stage oral tongue squamous cell carcinoma (OTSCC), elective neck dissection (END) is recommended when occult lymph node metastasis is suspected; however, there is no unanimous consensus on the risks and benefits of END in such cases. The management of clinically node-negative (cN0) OTSCC remains controversial. This study, therefore, aimed to evaluate the efficacy of END and its impact on the quality of life (QoL) of patients with cN0 OTSCC. Methods and analysis: This is a prospective, multicentre, nonrandomised observational study. The choice of whether to perform END at the same time as resection of the primary tumour is based on institutional policy and patient preference. The primary endpoint of this study is 3-year overall survival. The secondary endpoint are 3-year disease-specific survival, 3-year relapse-free survival and the impact on patient QoL. Propensity score-matching analysis will be performed to reduce selection bias. Ethics and dissemination: This study was approved by the Clinical Research Review Board of the Nagasaki University. The protocol of this study was registered at the University Hospital Medical Information Network Clinical Trials Registry. The datasets generated during the current study will be available from the corresponding author on reasonable request. The results will be disseminated internationally, through scientific and professional conferences and in peer-reviewed medical journals

Prevalence and Distribution of Ossified Lesions in the Whole Spine of Patients with Cervical Ossification of the Posterior Longitudinal Ligament A Multicenter Study (JOSL CT study)

Ossification of the posterior longitudinal ligament (OPLL) can cause severe and irreversible paralysis in not only the cervical spine but also the thoracolumbar spine. To date, however, the prevalence and distribution of OPLL in the whole spine has not been precisely evaluated in patients with cervical OPLL. Therefore, we conducted a multi-center study to comprehensively evaluate the prevalence and distribution of OPLL using multi-detector computed tomography (CT) images in the whole spine and to analyze what factors predict the presence of ossified lesions in the thoracolumbar spine in patients who were diagnosed with cervical OPLL by plain X-ray. Three hundred and twenty-two patients with a diagnosis of cervical OPLL underwent CT imaging of the whole spine. The sum of the levels in which OPLL was present in the whole spine was defined as the OP-index and used to evaluate the extent of ossification. The distribution of OPLL in the whole spine was compared between male and female subjects. In addition, a multiple regression model was used to ascertain related factors that affected the OP-index. Among patients with cervical OPLL, women tended to have more ossified lesions in the thoracolumbar spine than did men. A multiple regression model revealed that the OP-index was significantly correlated with the cervical OP-index, sex (female), and body mass index. Furthermore, the prevalence of thoracolumbar OPLL in patients with a cervical OP-index ≥ 10 was 7.8 times greater than that in patients with a cervical OP-index ≤ 5. The results of this study reveal that the extent of OPLL in the whole spine is significantly associated with the extent of cervical OPLL, female sex, and obesity

Protocol for a multicentre, prospective observational study of elective neck dissection for clinically node-negative oral tongue squamous cell carcinoma (END-TC study)

Introduction In early-stage oral tongue squamous cell carcinoma (OTSCC), elective neck dissection (END) is recommended when occult lymph node metastasis issuspected; however, there is no unanimous consensus on the risks and benefits of END in such cases. The management of clinically node-negative (cN0) OTSCCremains controversial. This study, therefore, aimed to evaluate the efficacy of END and its impact on the quality of life (QoL) of patients with cN0 OTSCC.Methods and analysis This is a prospective, multicentre, nonrandomised observational study. The choice of whether to perform END at the same time as resection of the primary tumour is based on institutional policy and patient preference. The primary endpoint of this study is 3-year overall survival. The secondary endpoints are3-year disease-specific survival, 3-year relapse-free survival and the impact on patient QoL. Propensity score-matching analysis will be performed to reduce selection bias.Ethics and dissemination This study was approved by the Clinical Research Review Board of the Nagasaki University. The protocol of this study was registered at the University Hospital Medical Information Network Clinical Trials Registry. The datasets generated during the current study will be available from the correspondingauthor on reasonable request. The results will be disseminated internationally, through scientific and professional conferences and in peer-reviewed medical journals

Internal marketing and employee satisfaction : a missing link in Japanese service management

Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management, 2003.Includes bibliographical references (leaves 96-98).The concepts and techniques of internal marketing and employee satisfaction are becoming very popular in western companies, supported by accomplishments in service management based on of the Service-Profit Chain and organizational behavior. However, it is still uncommon for Japanese service companies to introduce these concepts, being strongly influenced by Japanese culture and tradition. This thesis first explains internal marketing and employee satisfaction through existing literature and actual examples of U.S. banks. It then examines current Japanese service companies and the reasons for their practice, considering cultural influence. Furthermore, recognizing the importance of companies in adopting these concepts in the near future, I indicate how this can be achieved using examples in Japan.by Tsuyoshi Takeshita.M.B.A