A New Experiment to Study Hyperon CP Violation and the Charmonium System

Fermilab operates the world's most intense antiproton source, now exclusively dedicated to serving the needs of the Tevatron Collider. The anticipated 2009 shutdown of the Tevatron presents the opportunity for a world-leading low- and medium-energy antiproton program. We summarize the status of the Fermilab antiproton facility and review physics topics for which a future experiment could make the world's best measurements.Comment: 16 pages, 3 figures, to appear in Proceedings of CTP symposium on Supersymmetry at LHC: Theoretical and Experimental Perspectives, The British University in Egypt, Cairo, Egypt, 11-14 March 200

Multilevel semantic analysis and problem-solving in the flight domain

A computer based cockpit system which is capable of assisting the pilot in such important tasks as monitoring, diagnosis, and trend analysis was developed. The system is properly organized and is endowed with a knowledge base so that it enhances the pilot's control over the aircraft while simultaneously reducing his workload

A Re-evaluation of the “Oncogenic” Nature of Wnt/β-catenin Signaling in Melanoma and Other Cancers

In cancer, Wnt/β-catenin signaling is ubiquitously referred to as an “oncogenic” pathway that promotes tumor progression. This review examines how the regulation and downstream effects of Wnt/β-catenin signaling in cancer varies depending on cellular context, with a focus on malignant melanoma. We emphasize that the cellular homeostasis of Wnt/β-catenin signaling may represent a more appropriate concept than the simplified view of the Wnt/β-catenin pathway as either oncogenic or tumor-suppressing. Ultimately, a more refined understanding of the contextual regulation of Wnt/β-catenin signaling will be essential for addressing if and how therapeutic targeting of this pathway could be leveraged for patient benefit

L-Step Majority Logic Decoding

Coordinated Science Laboratory was formerly known as Control Systems LaboratoryJoint Services Electronics Program / DAAB 07-67-C-0199Rome Air Development Center / F30602-70-C-0014 (EMKC

Isotope effects in underdoped cuprate superconductors: a quantum phenomenon

We show that the unusual doping dependence of the isotope effects on transition temperature and zero temperature in - plane penetration depth naturally follows from the doping driven 3D-2D crossover, the 2D quantum superconductor to insulator transition (QSI) in the underdoped limit and the change of the relative doping concentration upon isotope substitution. Close to the QSI transition both, the isotope coefficient of transition temperature and penetration depth approach the coefficient of the relative dopant concentration, and its divergence sets the scale. These predictions are fully consistent with the experimental data and imply that close to the underdoped limit the unusual isotope effect on transition temperature and penetration depth uncovers critical phenomena associated with the quantum superconductor to insulator transition in two dimensions.Comment: 6 pages, 3 figure

An international multi-site, randomized controlled trial of a mindfulness-based psychoeducation group programme for people with schizophrenia

BackgroundWe aimed to test a mindfulness-based psycho-education group (MBPEG), versus conventional psycho-education group (CPEG) versus treatment-as-usual (TAU), in patients with schizophrenia-spectrum disorders over a 24-month follow-up.MethodsThis single-blind, multi-site, pragmatic randomized controlled trial was conducted in six community treatment facilities across three countries (Hong Kong, mainland China and Taiwan). Patients were randomly allocated to one of the treatment conditions, and underwent six months of treatment. The primary outcomes were changes in duration of rehospitalizations and mental state (PANSS) between baseline and one week, six, 12 and 18 months’ post treatment.ResultsA total of 300 patients in each country were assessed for eligibility between October 2013 and 30 April 2014,38 patients per country (n=342) were assigned to each treatment group and included in the intention-to-treat-analysis. There was a significant difference in the length of re-hospitalizations between the three groups over 24 months F (2,330) =5.23, p=0.005, with MBPEG participants having a shorter mean duration of re-hospitalizations than those in theother groups. The MBPEG and CPEG participants had significant differential changes in proportional ORs of complete remission (all individual PANSS item