Welfare Impacts of Rural to Urban Water Transfers: An Equilibrium Displacement Approach

Food Security and Poverty,

Simultaneous interplanetary scintillation and Heliospheric Imager observations of a coronal mass ejection

We describe simultaneous Interplanetary Scintillation (IPS) and STEREO Heliospheric Imager (HI) observations of a coronal mass ejection (CME) on 16 May 2007. Strong CME signatures were present throughout the IPS observation. The IPS raypath lay within the field-of-view of HI-1 on STEREO-A and comparison of the observations shows that the IPS measurements came from a region within a faint CME front observed by HI-1A. This front may represent the merging of two converging CMEs. Plane-of-sky velocity estimates based on time-height plots of the two converging CME structures were 325 kms?1 and 550 kms?1 for the leading and trailing fronts respectively. The plane-of-sky velocities determined from IPS ranged from 420 ± 10 kms?1 to 520 ± 20 kms?1. IPS results reveal the presence of micro-structure within the CME front which may represent interaction between the two separate CME events. This is the first time that it has been possible to interpret IPS observations of small-scale structure within an interplanetary CME in terms of the global structure of the event

A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol

The structures of two Dr adhesin (DraE) complexes with chloramphenicol derivatives, namely chloramphenicol succinate and bromamphenicol, have been solved. The structures reveal important functional groups for small-molecule binding and imply possible modifications to the molecule that would permit a more wide-ranging interaction without the toxic side effects associated with chloramphenicol

Asymmetric synthesis of secondary benzylic alcohols via arene chromium tricarbonyl complexes

ABSTRACT: The use of O-methyl-N-(alpha-methylbenzyl)hydroxylamine as a novel chiral auxiliary in asymmetric ortho-deprotonation of the (eta(6)-arene) chromium tricarbonyl complexes is described. Upon quenching of the resultant ortho-lithiated complex with an electrophile, 1,2-disubstituted (eta(6)-arene) chromium tricarbonyl complexes were obtained in good yield and excellent levels of diastereoselectivity.info:eu-repo/semantics/publishedVersio

A Precision Calculation of the Next-to-Leading Order Energy-Energy Correlation Function

The O(alpha_s^2) contribution to the Energy-Energy Correlation function (EEC) of e+e- -> hadrons is calculated to high precision and the results are shown to be larger than previously reported. The consistency with the leading logarithm approximation and the accurate cancellation of infrared singularities exhibited by the new calculation suggest that it is reliable. We offer evidence that the source of the disagreement with previous results lies in the regulation of double singularities.Comment: 6 pages, uuencoded LaTeX and one eps figure appended Complete paper as PostScript file (125 kB) available at: http://www.phys.washington.edu/~clay/eecpaper1/paper.htm

Context sensitive cardiac x-ray imaging: a machine vision approach to x-ray dose control

Modern cardiac x-ray imaging systems regulate their radiation output based on the thickness of the patient to maintain an acceptable signal at the input of the x-ray detector. This approach does not account for the context of the examination or the content of the image displayed. We have developed a machine vision algorithm that detects iodine-filled blood vessels and fits an idealized vessel model with the key parameters of contrast, diameter, and linear attenuation coefficient. The spatio-temporal distribution of the linear attenuation coefficient samples, when appropriately arranged, can be described by a simple linear relationship, despite the complexity of scene information. The algorithm was tested on static anthropomorphic chest phantom images under different radiographic factors and 60 dynamic clinical image sequences. It was found to be robust and sensitive to changes in vessel contrast resulting from variations in system parameters. The machine vision algorithm has the potential of extracting real-time context sensitive information that may be used for augmenting existing dose control strategies

Molecular evolution of the hyaluronan synthase 2 gene in mammals: implications for adaptations to the subterranean niche and cancer resistance

The naked mole-rat (NMR) Heterocephalus glaber is a unique and fascinating mammal exhibiting many unusual adaptations to a subterranean lifestyle. The recent discovery of their resistance to cancer and exceptional longevity has opened up new and important avenues of research. Part of this resistance to cancer has been attributed to the fact that NMRs produce a modified form of hyaluronan—a key constituent of the extracellular matrix—that is thought to confer increased elasticity of the skin as an adaptation for living in narrow tunnels. This so-called high molecular mass hyaluronan (HMM-HA) stems from two apparently unique substitutions in the hyaluronan synthase 2 enzyme (HAS2). To test whether other subterranean mammals with similar selection pressures also show molecular adaptation in their HAS2 gene, we sequenced the HAS2 gene for 11 subterranean mammals and closely related species, and combined these with data from 57 other mammals. Comparative screening revealed that one of the two putatively important HAS2 substitutions in the NMR predicted to have a significant effect on hyaluronan synthase function was uniquely shared by all African mole-rats. Interestingly, we also identified multiple other amino acid substitutions in key domains of the HAS2 molecule, although the biological consequences of these for hyaluronan synthesis remain to be determined. Despite these results, we found evidence of strong purifying selection acting on the HAS2 gene across all mammals, and the NMR remains unique in its particular HAS2 sequence. Our results indicate that more work is needed to determine whether the apparent cancer resistance seen in NMR is shared by other members of the African mole-rat clade.National Research Foundation (South Africa

Improved Nonrelativistic QCD for Heavy Quark Physics

We construct an improved version of nonrelativistic QCD for use in lattice simulations of heavy quark physics, with the goal of reducing systematic errors from all sources to below 10\%. We develop power counting rules to assess the importance of the various operators in the action and compute all leading order corrections required by relativity and finite lattice spacing. We discuss radiative corrections to tree level coupling constants, presenting a procedure that effectively resums the largest such corrections to all orders in perturbation theory. Finally, we comment on the size of nonperturbative contributions to the coupling constants.Comment: 40 pages, 2 figures (not included), in LaTe