2,194 research outputs found
Droplet deformation by short laser-induced pressure pulses
When a free-falling liquid droplet is hit by a laser it experiences a strong
ablation driven pressure pulse. Here we study the resulting droplet deformation
in the regime where the ablation pressure duration is short, i.e. comparable to
the time scale on which pressure waves travel through the droplet. To this end
an acoustic analytic model for the pressure-, pressure impulse- and velocity
fields inside the droplet is developed in the limit of small density
fluctuations. This model is used to examine how the droplet deformation depends
on the pressure pulse duration while the total momentum to the droplet is kept
constant. Within the limits of this analytic model, we demonstrate that when
the total momentum transferred to the droplet is small the droplet
shape-evolution is indistinguishable from an incompressible droplet
deformation. However, when the momentum transfer is increased the droplet
response is strongly affected by the pulse duration. In this later regime,
compressed flow regimes alter the droplet shape evolution considerably.Comment: Submitted to JF
Combination prevention: new hope for stopping the epidemic.
HIV research has identified approaches that can be combined to be more effective in transmission reduction than any 1 modality alone: delayed adolescent sexual debut, mutual monogamy or sexual partner reduction, correct and consistent condom use, pre-exposure prophylaxis with oral antiretroviral drugs or vaginal microbicides, voluntary medical male circumcision, antiretroviral therapy (ART) for prevention (including prevention of mother to child HIV transmission [PMTCT]), treatment of sexually transmitted infections, use of clean needles for all injections, blood screening prior to donation, a future HIV prime/boost vaccine, and the female condom. The extent to which evidence-based modalities can be combined to prevent substantial HIV transmission is largely unknown, but combination approaches that are truly implementable in field conditions are likely to be far more effective than single interventions alone. Analogous to PMTCT, "treatment as prevention" for adult-to-adult transmission reduction includes expanded HIV testing, linkage to care, antiretroviral coverage, retention in care, adherence to therapy, and management of key co-morbidities such as depression and substance use. With successful viral suppression, persons with HIV are far less infectious to others, as we see in the fields of sexually transmitted infection control and mycobacterial disease control (tuberculosis and leprosy). Combination approaches are complex, may involve high program costs, and require substantial global commitments. We present a rationale for such investments and cite an ongoing research agenda that seeks to determine how feasible and cost-effective a combination prevention approach would be in a variety of epidemic contexts, notably that in a sub-Saharan Africa
Genetic evidence of farmed straying and introgression in Swedish wild salmon populations
Escaped farmed Atlantic salmon represent a well-documented and ongoing threat to wild conspecific populations. In Norway, the world-leading producer of farmed salmon, annual monitoring of straying and genetic introgression by farmed escapees in wild salmon rivers has been carried out since the late 1980s. In this study, we applied molecular and statistical methods routinely used in the Norwegian monitoring programme to investigate the magnitude of escaped farmed salmon and genetic introgression in salmon rivers on the west coast of Sweden, where suspected escapees have been observed. Our results confirm that escaped farmed salmon stray, successfully spawn, and produce offspring at levels similar to those observed in neighbouring Norway. These findings raise concerns over population productivity and long-term viability and highlight the need for more permanent monitoring of the presence and consequences of escaped farmed salmon in Swedish salmon rivers. Our results further illustrate that farmed gene flow may constitute a transboundary problem with potential international implications
The Future of American Fertility
This paper reviews the major social and demographic forces influencing American fertility levels with the aim of predicting changes during the next three decades. Increases in the Hispanic population and in educational attainment are expected to have modest and offsetting effects on fertility levels. A cessation of the recent pattern of increasing ages at childbearing will at some point put upward pressure on period (but not cohort) fertility rates. Higher relative wages for women and better contraception have empowered women and fundamentally altered marriage and relations between the sexes. But women's childbearing has become less dependent upon stable relations with men, and educational differences in intended fertility have narrowed. One explanation of higher fertility in the U.S. than in other developed countries is that its institutions have adapted better to rising relative wages for women and the attendant increase in women's labor force participation.
Identification of Distillation Process Dynamics Comparing Process Knowledge and Black Box Based Approaches
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