1,350 research outputs found
Integrated Expert Management Knowledge on OSI Network Management Objects
The management of modern telecommunications networks must satisfy
ever-increasing operational demands. We propose a study for the improvement
of intelligent administration techniques in telecommunications networks.
This task is achieved by integrating knowledge base of expert system within the
management information used to manage a network. For this purpose, an extension
of OSI management framework specifications language has been added
and investigated. For this goal, we shall use the language Guidelines for the
Definition of Managed Objects (GDMO) and a new property named RULE
which gathers important aspects of the facts and the knowledge base of the embedded
expert system. Networks can be managed easily by using this proposed
integration
Cognitive Information Processing
Contains reports on two research projects.National Institutes of Health (Grant 5 PO1 GM14940 -05
Assessing conceptual knowledge in three online engineering courses: theory of computation and compiler construction, operating systems, and signal and systems
In the current decade understanding conceptual knowledge should be an important area of engineering science. However, it is not as widespread in
this field as it is in the areas of education and psychology. Learning conceptual knowledge in engineering science could help instructors to adapt their
lectures in order to overcome student misconceptions, to reinforce the learning process, and to check whether students are able to identify key
features of a problem. Different methods are provided by authors to assess conceptual knowledge. One is to design and develop a concept inventory
with the objective of identifying possible student misconceptions through multiple-choice questions. Another method consists of asking each student to
answer a question by submitting a written explanation. This study provides two procedures for the assessment of conceptual knowledge based on the
latter method. The first procedure is applied to online computer science students enrolled on an Operating Systems course. The second procedure is
applied to online communication students enrolled on a Signals and Systems course. Both procedures are focused not only on assessing but also on
searching for causes of potential student misconceptions. These procedures could help other instructors to assess conceptual knowledge on other
engineering courses.Universidad a Distancia de Madrid, UDIMA2018-1
Heat-transfer and pressure distributions on 60 deg and 70 deg swept delta wings having turbulent boundary layers
Heat-transfer and pressure distributions on 60 and 70 deg swept delta wings with turbulent boundary layer
Delayed commutation in quantum computer networks
In the same way that classical computer networks connect and enhance the
capabilities of classical computers, quantum networks can combine the
advantages of quantum information and communications. We propose a
non-classical network element, a delayed commutation switch, that can solve the
problem of switching time in packet switching networks. With the help of some
local ancillary qubits and superdense codes we can route the information after
part of it has left the network node.Comment: 4 pages. 4 figures. Preliminar versio
GLOVEBOX DISMANTLEMENT AND EQUIPMENT PROTECTION IN CONTAMINATED ENVIRONMENTS
ABSTRACT It has been revealed from the experiences of Decontamination and Decommissioning (D&D) activities that even a small improvement in performance can result in significant risk reduction and cost savings. For example, Race Scan Ear Mic System, which was originally developed for communications between racecar drivers and crews in loud environments, has been successfully applied to D&D work and proved to enhance worker safety and communications. Glovebox dismantlement is an important and costly process in D&D activities of nuclear facilities. Adequate decontamination and size reduction of the gloveboxes are especially important in this activity because they have the potential to reduce risks and costs significantly. This paper presents some simple approaches to support D&D tasks and discusses their potential advantages. Examples discussed include: • Repeated shear wiping of large pipes and ducts • Application of thin layers on radiological counters for uninterrupted use • Partial use of robotics for glovebox dismantling The paper also discusses schematics for protecting equipment interiors and/or glovebox inner surfaces from contamination, which may result in significant savings and waste minimization upon future dismantlement. Examples discussed include: • Smart coating for contamination prevention • Protecting equipment by geometrically simple cove
Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival
MiRNAs regulate gene expression at a post-transcriptional level and their dysregulation can play major roles in the pathogenesis of many different forms of cancer, including neuroblastoma, an often fatal paediatric cancer originating from precursor cells of the sympathetic nervous system. We have analyzed a set of neuroblastoma (n = 145) that is broadly representative of the genetic subtypes of this disease for miRNA expression (430 loci by stem-loop RT qPCR) and for DNA copy number alterations (array CGH) to assess miRNA involvement in disease pathogenesis. The tumors were stratified and then randomly split into a training set (n = 96) and a validation set (n = 49) for data analysis. Thirty-seven miRNAs were significantly over-or under-expressed in MYCN amplified tumors relative to MYCN single copy tumors, indicating a potential role for the MYCN transcription factor in either the direct or indirect dysregulation of these loci. In addition, we also determined that there was a highly significant correlation between miRNA expression levels and DNA copy number, indicating a role for large-scale genomic imbalances in the dysregulation of miRNA expression. In order to directly assess whether miRNA expression was predictive of clinical outcome, we used the Random Forest classifier to identify miRNAs that were most significantly associated with poor overall patient survival and developed a 15 miRNA signature that was predictive of overall survival with 72.7% sensitivity and 86.5% specificity in the validation set of tumors. We conclude that there is widespread dysregulation of miRNA expression in neuroblastoma tumors caused by both over-expression of the MYCN transcription factor and by large-scale chromosomal imbalances. MiRNA expression patterns are also predicative of clinical outcome, highlighting the potential for miRNA mediated diagnostics and therapeutics
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