688 research outputs found
Isotope effects in the specific heat of solid neon
Isotope effects in specific heat of solid neo
Gene network understanding and analysis
Gene regulatory network (GRN) is a collection of regulators that interact with each other in the cell to govern the gene expression levels of mRNA and proteins. These regulators can either be DNA, RNA, protein and their complex. Transcriptional gene regulation is an important mechanisms in which an in-depth study can lead to various practical applications, and a greater understanding of how organisms control their cellular behavior. One of the most widely studied organisms in gene regulatory networks are the Mycobacterium tuberculosis and Corynebacterium glutamicum ATCC 13032.
Gene co-expression networks are of biological interests due to co-expressed genes which are controlled by the same transcriptional regulatory programs, as well as, studying the functionality of genes in a system-level. Correlation networks are increasingly being used in research applications, especially in the field of bioinformatics. It facilitates networks based on gene screening methods which can be used to identify biomarkers or therapeutic targets. Computational methods use for the development of network models, as well as, the analysis of their functionality proved to be of valuable resources
A water level relationship between consecutive gauge stations along Solim\~oes/Amazonas main channel: a wavelet approach
Gauge stations are distributed along the Solim\~oes/Amazonas main channel to
monitor water level changes over time. Those measurements help quantify both
the water movement and its variability from one gauge station to the next
downstream. The objective of this study is to detect changes in the water level
relationship between consecutive gauge stations along the Solim\~oes/Amazonas
main channel, since 1980. To carry out the analyses, data spanning from 1980 to
2010 from three consecutive gauges (Tefe, Manaus and Obidos) were used to
compute standardized daily anomalies. In particular for infra-annual periods it
was possible to detect changes for the water level variability along the
Solim\~oes/Amazonas main channel, by applying the Morlet Wavelet Transformation
(WT) and Wavelet Cross Coherence (WCC) methods. It was possible to quantify the
waves amplitude for the WT infra-annual scaled-period and were quite similar to
the three gauge stations denoting that the water level variability are related
to the same hydrological forcing functions. Changes in the WCC was detected for
the Manaus-Obidos river stretch and this characteristic might be associated
with land cover changes in the floodplains. The next steps of this research,
will be to test this hypotheses by integrating land cover changes into the
floodplain with hydrological modelling simulations throughout the time-series
Charging of highly resistive granular metal films
We have used the Scanning Kelvin probe microscopy technique to monitor the
charging process of highly resistive granular thin films. The sample is
connected to two leads and is separated by an insulator layer from a gate
electrode. When a gate voltage is applied, charges enter from the leads and
rearrange across the sample. We find very slow processes with characteristic
charging times exponentially distributed over a wide range of values, resulting
in a logarithmic relaxation to equilibrium. After the gate voltage has been
switched off, the system again relaxes logarithmically slowly to the new
equilibrium. The results cannot be explained with diffusion models, but most of
them can be understood with a hopping percolation model, in which the
localization length is shorter than the typical site separation. The technique
is very promising for the study of slow phenomena in highly resistive systems
and will be able to estimate the conductance of these systems when direct
macroscopic measurement techniques are not sensitive enough.Comment: 8 pages, 7 figure
Surface-enhanced ordering and layer-thinning transitions in freely suspended smectic-A films
4 pages, 3 figures.-- PACS nrs.: 61.30.Cz, 64.70.Md, 68.45.Gd.We propose a physical mechanism which leads to surface-enhanced smectic-A ordering (SESO) at the free surface of a model liquid crystal. We also provide an explanation, based on a density-functional theory, for recent experimental results for the melting behavior of freely suspended smectic (FSS) films. It is shown that stepwise layer-thinning transitions do not usually occur during melting of FSS films, despite the presence of SESO. We find that thinning transitions similar to those observed experimentally occur under conditions such that the film interior melts to a nematic rather than isotropic liquid phase.This work was supported by the DGICyT of Spain (Grant No. PB94-0005-C02) and NSERC of Canada.Publicad
Spin quantum Hall effect and plateau transitions in multilayer network models
We study the spin quantum Hall effect and transitions between Hall plateaus
in quasi two-dimensional network models consisting of several coupled layers.
Systems exhibiting the spin quantum Hall effect belong to class C in the
symmetry classification for Anderson localisation, and for network models in
this class there is an established mapping between the quantum problem and a
classical one involving random walks. This mapping permits numerical studies of
plateau transitions in much larger samples than for other symmetry classes, and
we use it to examine localisation in systems consisting of weakly coupled
layers. Standard scaling ideas lead one to expect distinct plateau
transitions, but in the case of the unitary symmetry class this conclusion has
been questioned. Focussing on a two-layer model, we demonstrate that there are
two separate plateau transitions, with the same critical properties as in a
single-layer model, even for very weak interlayer coupling.Comment: 5 pages, 6 figure
Nanoscale Charge Density and Dynamics in Graphene Oxide
Graphene oxide (GO) is widely used as a component in thin film optoelectronic device structures for practical reasons because its electronic and optical properties can be controlled. Progress critically depends on elucidating the nanoscale electronic structure of GO. However, direct experimental access is challenging because of its disordered and nonconductive character. Here, we quantitatively mapped the nanoscopic charge distribution and charge dynamics of an individual GO sheet by using Kelvin probe force microscopy (KPFM). Charge domains are identified, presenting important charge interactions below distances of 20 nm. Charge dynamics with very long relaxation times of at least several hours and a logarithmic decay of the time correlation function are in excellent agreement with Monte Carlo simulations, revealing an universal hopping transport mechanism best described by Efros-Shklovskii''s law. © 2021 The Authors. Published by American Chemical Society
Biaxial nematic phases in fluids of hard board-like particles
We use density-functional theory, of the fundamental-measure type, to study
the relative stability of the biaxial nematic phase, with respect to
non-uniform phases such as smectic and columnar, in fluids made of hard
board-like particles with sizes . A
restricted-orientation (Zwanzig) approximation is adopted. Varying the ratio
while keeping , we
predict phase diagrams for various values of which include all the
uniform phases: isotropic, uniaxial rod- and plate-like nematics, and biaxial
nematic. In addition, spinodal instabilities of the uniform phases with respect
to fluctuations of the smectic, columnar and plastic-solid type, are obtained.
In agreement with recent experiments, we find that the biaxial nematic phase
begins to be stable for . Also, as predicted by previous
theories and simulations on biaxial hard particles, we obtain a region of
biaxility centred on which widens as
increases. For \kappa_2\agt 5 the region of the
packing-fraction vs. phase diagrams exhibits interesting topologies
which change qualitatively with . We have found that an increasing
biaxial shape anisotropy favours the formation of the biaxial nematic phase.
Our study is the first to apply FMT theory to biaxial particles and, therefore,
it goes beyond the second-order virial approximation. Our prediction that the
phase diagram must be asymmetric is a genuine result of the present approach,
which is not accounted for by previous studies based on second-order theories.Comment: Preprint format. 18 pages, 5 figure
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