An exploratory investigation of the effect of a plastic coating on the profile drag of a practical-metal-construction sailplane airfoil

The Langley low-turbulence pressure tunnel to determine the effect of a plastic coating on the profile drag of a practical-metal-construction sailplane airfoil was investigated. The model was tested with three surface configurations: (1) filled, painted, and sanded smooth; (2) rough bare metal; and (3) plastic-coated. The results are compared with data for the design airfoil (Wortmann FX 67-K-170/17) from another low-turbulence wind tunnel. The investigation was conducted at Reynolds numbers based on airfoil chord of 1.1 x 10 to the 6th power, 2.2 x 10 to the 6th power, and 3.3 x 10 to the 6th power at a Mach number of 0.10

Low-speed aerodynamic characteristics of a 13-percent-thick airfoil section designed for general aviation applications

Wind-tunnel tests were conducted to determine the low-speed section characteristics of a 13 percent-thick airfoil designed for general aviation applications. The results were compared with NACA 12 percent-thick sections and with the 17 percent-thick NASA airfoil. The tests were conducted ovar a Mach number range from 0.10 to 0.35. Chord Reynolds numbers varied from about 2,000,000 to 9,000,000

Apollo to Artemis: Mining 50-Year Old Records to Inform Future Human Lunar Landing Systems

Under the Artemis lunar exploration program, NASA is committed to landing American astronauts on the moon by 2024. While NASAs new Space Launch System rocket and Orion capsule will carry astronauts from Earth to the Gateway, the human lunar landing system has not yet been fully defined. As in the Apollo program, there are concerns for vehicle weight and internal volume such that seats may not be desirable, and standing during lunar descent and ascent may be a preferred engineering solution. With such a design, astronauts will experience +GZ (head-to-foot) accelerations during capsule accelerations, and it is unclear whether spaceflight deconditioned astronauts can tolerate these. Apollo astronauts stood during lunar descent and ascent, and the data contained in the early program records for those missions represent a unique resource that may provide insights to the cardiovascular stress associated with this human landing system design

Predictors of survival in a cohort of patients with polymyositis and dermatomyositis: effect of corticosteroids, methotrexate and azathioprine

Introduction: The idiopathic inflammatory myopathies are rare diseases for which data regarding the natural history, response to therapies and factors affecting mortality are needed. We performed this study to examine the effects of treatment and clinical features on survival in polymyositis and dermatomyositis patients. Methods: A total of 160 consecutive patients (77 with polymyositis and 83 with dermatomyositis) seen at the University of Michigan from 1997 to 2003 were included. Medical records were abstracted for clinical, laboratory and therapeutic data, including initial steroid regimen and immunosuppressive use. State vital records were utilized to derive mortality and cause of death data. Survival was modeled by left-truncated Kaplan-Meier estimation and Cox regression. Results: The 5- and 10-year survival estimates were 77% (95% CI = 66 to 85), and 62% (95% CI = 48 to 73), respectively, and the rates were similar for polymyositis and dermatomyositis. Survival between the sexes was similar through 5 years and significantly lower thereafter for males (10-year survival: 18% male, 73% female; P = 0.002 for 5- to 10-year interval). The sex disparity was restricted to the polymyositis group. Increased age at diagnosis and non-Caucasian race were associated with lower survival. Intravenous versus oral corticosteroid use was associated with a higher risk of death among Caucasians (HR = 10.6, 95% CI = 2.1 to 52.8). Early survival between patients treated with methotrexate versus azathioprine was similar, but survival at 10 years was higher for the methotrexate-treated group (76% vs 52%, P = 0.046 for 5- to 10-year interval). Conclusions: Patients treated initially with intravenous corticosteroids had higher mortality, which was likely related to disease severity. Both methotrexate and azathioprine showed similar early survival benefits as first-line immunosuppressive drugs. Survival was higher between 5 and 10 years in the methotrexate-treated group, but could not be confirmed in multivariable modeling for the full follow-up period. Other important predictors of longterm survival included younger age, female sex and Caucasian race.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90025/1/IIM_ART2012.pdf1611

Toilet talk: (Trans)Gendered negotiation of public spaces

Public toilet provision in the UK fails to meet the needs of cis women while trans communities are absent from current building regulations. This research explores how individuals negotiate differing positions on toilet provision and accessibility. The data was formed of online posts on Dezeen, a forum for building design professionals, and Mumsnet, a parenting forum, in response to the Ministry of Housing and Local Government ‘Technical review on increasing accessibility and provision of toilets for men and women’. Discursive Psychology was used to explore how accessibility to toilets is constructed. There is also an opportunity to explore how a discursive approach can be applied interdisciplinary with town planning and the built environment. Gender identities are situated and constructed within public toilets. Talk about refuge in public bathrooms involved the negotiation of who belonged in differing gender categories and who warranted a need for refuge. Where men are explicitly acknowledged as an issue, cis and trans women are collectively identified as requiring a safe space. Cis women are presented as a threat to trans women and other cis women who are misgendered. Discourse about toilet provision draws upon both heteronormative ideology to challenge access to trans people and others who challenge normative gender roles. Talk about toilets involves warranting ‘place-identity’ as gender identity is situated and access limited to those who are constructed as belonging

Assessing the Risk of Crew Injury Due to Dynamic Loads During Spaceflight

No abstract availabl

Exciton lifetime and emission polarization dispersion in strongly in-plane asymmetric nanostructures

We present experimental and theoretical investigation of exciton recombination dynamics and the related polarization of emission in highly in-plane asymmetric nanostructures. Considering general asymmetry- and size-driven effects, we illustrate them with a detailed analysis of InAs/AlGaInAs/InP elongated quantum dots. These offer a widely varied confinement characteristics tuned by size and geometry that are tailored during the growth process, which leads to emission in the application-relevant spectral range of 1.25-1.65 {\mu}m. By exploring the interplay of the very shallow hole confining potential and widely varying structural asymmetry, we show that a transition from the strong through intermediate to even weak confinement regime is possible in nanostructures of this kind. This has a significant impact on exciton recombination dynamics and the polarization of emission, which are shown to depend not only on details of the calculated excitonic states but also on excitation conditions in the photoluminescence experiments. We estimate the impact of the latter and propose a way to determine the intrinsic polarization-dependent exciton light-matter coupling based on kinetic characteristics.Comment: 11 pages, 8 figure

Environmental memory from a circadian oscillator:the Arabidopsis thaliana clock differentially integrates perception of photic vs. thermal entrainment

The constraint of a rotating earth has led to the evolution of a circadian clock that drives anticipation of future environmental changes. During this daily rotation, the circadian clock of Arabidopsis thaliana (Arabidopsis) intersects with the diurnal environment to orchestrate virtually all transcriptional processes of the plant cell, presumably by detecting, interpreting, and anticipating the environmental alternations of light and temperature. To comparatively assess differential inputs toward phenotypic and physiological responses on a circadian parameter, we surveyed clock periodicity in a recombinant inbred population modified to allow for robust periodicity measurements after entrainment to respective photic vs. thermal cues, termed zeitgebers. Lines previously thermally entrained generally displayed reduced period length compared to those previously photically entrained. This differential zeitgeber response was also detected in a set of diverse Arabidopsis accessions. Thus, the zeitgebers of the preceding environment direct future behavior of the circadian oscillator. Allelic variation at quantitative trait loci generated significant differences in zeitgeber responses in the segregating population. These were important for periodicity variation dependent on the nature of the subsequent entrainment source. Collectively, our results provide a genetic paradigm for the basis of environmental memory of a preceding environment, which leads to the integrated coordination of circadian periodicity

Coherent response of lakes in Ontario, Canada to reductions in sulphur deposition: the effects of climate on sulphate concentrations

International audienceSulphate deposition in south-central Ontario declined between 1976 and 2000 by more than 50%, whereas lake sulphate (SO42?) concentrations decreased by, on average, only half as much. To investigate the factors that controlled this slower than expected response, the temporal patterns in lake SO42? concentrations were compared with patterns in both deposition and climate, since climate has a major influence on the hydrological cycle in this part of the continent. To do this, the temporal coherence in SO42? concentrations between 9 lake basins was estimated using the intraclass correlation from a repeated-measures analysis of variance and two subsets of lakes were found (six in one group, four in the other), each with lakes having synchronous patterns. One subset (4 lakes) included the 3 with the longest water replenishment times (>3.4 yr) which are expected to respond to decreases in SO42? deposition more slowly. However, the average pattern reflecting the temporal changes of each of the two subsets was very similar. The response of both subsets of lakes to the decreasing SO42? deposition over two decades was independent of the degree of acidification or sensitivity to acidification of the lakes. In a determination of which factors best predicted each of those two subsets' SO42? time series, good predictive models were produced by regional/global-scale climate indices, specifically the Southern Oscillation Index (SOI) describing the El Niño Southern Oscillation (ENSO) and the North Atlantic Oscillation Index (NAOI), as well as by SO42? deposition indices. When the predictor variables were combined, models which described the long-term changes in lake SO42? concentration best included the SOI, the NAOI and SO42? deposition. Thus, large-scale climate factors play a major role in determining the response of aquatic systems to changes in SO42? deposition, perhaps through their influence on lake and/or catchment processes that effectively delay recovery. Keywords: Atmospheric deposition, lake recovery, temporal trends, climate, temporal coherenc