Removal of an Upper Third Molar from the Maxillary Sinus

The maxillary sinus or antrum is the largest of the paranasal sinuses. It is located in the maxillary bone and has a proximity to the apexes of upper molars and premolars, which allows it to form a direct link between the sinus and the oral cavity. Dislocation of a foreign body or tooth to the interior of a paranasal sinus is a situation that can occur as a result of car accidents, firearm attacks, or iatrogenic in surgical procedures. Therefore, it is necessary to know how to treat this kind of situation. This study’s objective is to report the case of a 23-year-old female patient, leucoderma, who sought treatment from the Surgical Unit at the Dental Faculty of the Federal University of Sergipe. She had a history of pain and edema in the right side of the genian region and two failed attempts at removing dental unit (DU) 18. The extraoral clinical exam revealed intense edema of the left hemiface with signs of infection, excoriation of the labial commissure, hematoma, a body temperature of 39°C, and a limited ability to open her mouth. The patient was medicated and treated surgically. The tooth was removed from the maxillary sinus with caution, as should have been done initially

Histological Effects of Creatine Monohydrate Supplementation on Muscle Tissue in Wistar Rats

Creatine is a dietary supplement with the potential to stimulate the phosphocreatine pathway and protein synthesis, through the stimulation of PI3eK/AKT and mTOR responsible for the proliferation and differentiation of satellite cells, responsible for hypertrophy. The present study aimed to evaluate the morphological effects of the use of creatine monohydrate on the soleus muscle tissue of 26-month-old Wistar rats. Methods: Twelve Wistar rats were divided into two groups of six animals each. Group 1 was not supplemented with creatine and received a standard diet consisting of water and food. Group 2 received the same diet, but was supplemented with creatine monohydrate at a dose of 0.03 mg/kg of body weight diluted in 200 ml of drinking water for 8 weeks. Results: The supplementation promoted morphological and morphometric effects on the soleus muscle tissue, promoting changes in the perimeter and area of the muscles of the animals treated with the supplement. It is estimated that this supplement may promote, in addition to increasing the cross-sectional area of myocytes, increased stimulation of the protein synthesis pathway associated with PI3K/AKT

Mulheres submetidas à cirurgia bariátrica: um estudo reflexivo sobre os cuidados reprodutivos e psicossociais / Women undergoing bariatric surgery: a reflective study on reproductive and psychosocial care

Este estudo objetivou desenvolver uma reflexão teórico-crítica a respeito de informações na literatura sobre os cuidados reprodutivos e psicossociais com as mulheres submetidas à cirurgia bariátrica. Os descritores: Obesidade, Cirurgia bariátrica; Saúde reprodutiva; Depressão; Qualidade de vida e seus sinônimos foram utilizados nas bases de dados Medline, Lilacs, Google Scholar, Cochrane e Pubmed para buscar artigos relacionados com a temática. No estudo discute-se a cirurgia bariátrica e os seus aspectos epidemiológicos e psicossociais, considerando a sua relação com a fertilidade, sexualidade, gestação e contracepção, ressaltando-se o uso do sistema intrauterino liberador de levonorgestrel. A gestação é contraindicada nos primeiros meses após a cirurgia, portanto, mulheres no menacme devem receber orientações pré operatórias sobre contracepção segura, que ao mesmo tempo interfira minimamente sobre a perda de peso, função sexual e estado psicosocial, além de atuar no controle da anemia ferropriva e colaborar para a compensação de suas comorbidades. Portanto, a mulher submetida a cirurgia bariátrica precisa de atendimento na sua integralidade, pois após o procedimento cirúrgico a usuária possui várias carências, necessitando de uma assistência de qualidade e resoluta que contemple os fatores relacionados a saúde reprodutiva, a sexualidade e os aspectos psicossociais

Extensionist pioneering at the Universidade do Estado do Rio Grande do Norte: online course in first aids and basic life support

The university´s extension has as main aim to develop interventions that impact and embrace the society. The first aids and basic life support (BLS) in the UERN has as principal objective to include, by means of the dissemination of the practical and theoretical knowledge, the first aids procedures turned to the general public, by means of an accessible language and of dynamical methodologies. Conditions of urgency and emergency are presented, usually the most frequent in the pre-hospital´ treatment, where precocious intervention word as the way to save lives, by means of practical and theoretical classes. This work tried to show how these initiatives have been developed, implanting new modalities of access to technical information about first aids, as well as all the used strategies to train effectively academic and not academic people. This Project have been under execution since 2013 and, consequently due to the importance of the theme, every year, the number of trained participants have been increasing, corroborating to the quality of the information presented and to the backup of the university and the citizens. In this way, it is of extremely importance the continuity of the permanent character of the course, in order to promote the importance and constant actualization in the field so neglected and recurrent, also considering, the promotion of the health in the virtual world too, bringing the information to any place in the world with internet access

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Understanding the relation between Zika virus infection during pregnancy and adverse fetal, infant and child outcomes: a protocol for a systematic review and individual participant data meta-analysis of longitudinal studies of pregnant women and their infants and children

IntroductionZika virus (ZIKV) infection during pregnancy is a known cause of microcephaly and other congenital and developmental anomalies. In the absence of a ZIKV vaccine or prophylactics, principal investigators (PIs) and international leaders in ZIKV research have formed the ZIKV Individual Participant Data (IPD) Consortium to identify, collect and synthesise IPD from longitudinal studies of pregnant women that measure ZIKV infection during pregnancy and fetal, infant or child outcomes.Methods and analysisWe will identify eligible studies through the ZIKV IPD Consortium membership and a systematic review and invite study PIs to participate in the IPD meta-analysis (IPD-MA). We will use the combined dataset to estimate the relative and absolute risk of congenital Zika syndrome (CZS), including microcephaly and late symptomatic congenital infections; identify and explore sources of heterogeneity in those estimates and develop and validate a risk prediction model to identify the pregnancies at the highest risk of CZS or adverse developmental outcomes. The variable accuracy of diagnostic assays and differences in exposure and outcome definitions means that included studies will have a higher level of systematic variability, a component of measurement error, than an IPD-MA of studies of an established pathogen. We will use expert testimony, existing internal and external diagnostic accuracy validation studies and laboratory external quality assessments to inform the distribution of measurement error in our models. We will apply both Bayesian and frequentist methods to directly account for these and other sources of uncertainty.Ethics and disseminationThe IPD-MA was deemed exempt from ethical review. We will convene a group of patient advocates to evaluate the ethical implications and utility of the risk stratification tool. Findings from these analyses will be shared via national and international conferences and through publication in open access, peer-reviewed journals.Trial registration numberPROSPERO International prospective register of systematic reviews (CRD42017068915).</jats:sec