Towards establishing Lepton Flavour Universality violation in Bˉ→Kˉ∗ℓ+ℓ−\bar{B}\to \bar{K}^*\ell^+\ell^- decays

Rare semileptonic $b \to s \ell^+ \ell^-$ transitions provide some of the most promising frameworks to search for new physics effects. Recent analyses of these decays have indicated an anomalous behaviour in measurements of angular distributions of the decay $B^0\to K^*\mu^+\mu^-$ and lepton-flavour-universality observables. Unambiguously establishing if these deviations have a common nature is of paramount importance in order to understand the observed pattern. We propose a novel approach to independently and complementary probe this hypothesis by performing a simultaneous amplitude analysis of $\bar{B}^0 \to \bar{K}^{*0} \mu^+\mu^-$ and $\bar{B}^0 \to \bar{K}^{*0} e^+e^-$ decays. This method enables the direct determination of observables that encode potential non-equal couplings of muons and electrons, and are found to be insensitive to nonperturbative QCD effects. If current hints of new physics are confirmed, our approach could allow an early discovery of physics beyond the standard model with LHCb run II data sets.Comment: 6 pages, 7 figures. Matching the journal versio

zfit: scalable pythonic fitting

Statistical modeling is a key element in many scientific fields and especially in High-Energy Physics (HEP) analysis. The standard framework to perform this task in HEP is the C++ ROOT/RooFit toolkit; with Python bindings that are only loosely integrated into the scientific Python ecosystem. In this paper, zfit, a new alternative to RooFit written in pure Python, is presented. Most of all, zfit provides a well defined high-level API and workflow for advanced model building and fitting, together with an implementation on top of TensorFlow, allowing a transparent usage of CPUs and GPUs. It is designed to be extendable in a very simple fashion, allowing the usage of cutting-edge developments from the scientific Python ecosystem in a transparent way. The main features of zfit are introduced, and its extension to data analysis, especially in the context of HEP experiments, is discussed.Comment: 12 pages, 2 figure

AN APPROACH TO POSITIONAL QUALITY CONTROL METHODS FOR AIRBORNE INSAR HIGH-RESOLUTION X-BAND ORTHOIMAGES AND P-BAND DIGITAL TERRAIN MODEL

The positional validation of datasets is an important step for cartography studies since it allows learning about its accuracy, and also indicates the data process quality. However, the positional validation of Synthetic Aperture Radar (SAR) datasets have some additional challenges when compared to optical images due to the geometric distortions. We employ existing targets such as traffic signs and lampposts in the scene and identify them on the image as control points. We performed the validation of the geographic coordinates used as planialtimetric positional control points, using both the amplitude backscattering orthoimage and the Digital Terrain Model (DTM) generated from the InSAR system. We employed the NMAS, ASPRS and NSSDA tests along with information by the Brazilian Standards. This validation showed these control points presented the following results for 1:10,000 scale: NMAS test – class “A” in PEC and PEC-PCD; ASPRS test – RMSEx = 1.317m, RMSEy= 1.231m and RMSEz = 1.145m; and NSSDA test – RMSEr = 1,802m, Precisionr = 3.118m and Precisionz= 2.244m. These results prove we can use the proposed targets as control points and the used InSAR datasets meet the expected quality for generation of geotechnic products for 1:10,000 scale

Risco de diabetes tipo 2 na população beneficiária de RSI de São Brás de Alportel

Tema: A prevenção primária da diabetes tipo 2 deve incidir sobretudo na redução dos fatores de risco vulneráveis e conhecidos da etiologia da doença. Objetivo: Diminuir o risco de diabetes tipo 2 na população beneficiária de Rendimento Social de Inserção de São Brás de Alportel. Metodologia: Assente na metodologia do planeamento em saúde foi implementado um projeto de intervenção comunitária. Resultados: Das 114 pessoas observadas, 40 apresentam risco moderado ou superior de desenvolverem diabetes tipo 2 entre 2 e 10 anos; 30 têm antecedentes familiares de diabetes; 36 têm índice de massa corporal superior a 30 Kg/m2; 34 têm valores de pressão arterial classificada como préhipertensão; 54 apresentam colesterol elevado; apenas 18 comem vegetais e/ou fruta diariamente; só 37 praticam diariamente exercício físico durante pelo menos 30 minutos; 46 fumam diariamente e 20 consomem bebidas alcoólicas diariamente. Considerações finais: As estratégias assentaram na promoção de estilos de vida saudáveis, baseadas na educação para a saúde; ### ABSTRACT: Risks of Diabetes Type 2 in the population of São Brás de Alportel, currently receiving the Social Services Help Theme and theoretical: The primary prevention of diabetes type 2, should be, most of all, focused on the reduction of the most known risks of the etiology of this disease. Main Goal: Reduce the risks of diabetes type 2 on the population of São Brás de Alportel, currently receiving the Social Services Help (RSI). Methodology: Based on the methodology of health planning, was implemented a project in this community. Results: from the 114 individuals observed, 40 of them presented a medium to high risk of develop diabetes type 2, between 2 to 10 years; 30 of them have family history of diabetes; 36 have IMC above 30 Kg/m2; 34 have blood pressure values classified as pre-hypertension; 54 have high cholesterol; only 18 eat vegetables and/or fruit on a daily basis; only 37 practice physical exercise daily minimum 30 minutes; 46 smoke daily and 20 consume alcohol daily. Final Considerations: The main plan was promoting healthy life styles based on health education

O grado Apocynoid (Apocynaceae) no Nordeste oriental do Brasil

A taxonomic study of the representatives of the Apocynoid grade (Apocynaceae) in Eastern Northeast Brazil is presented, and includes an identification key, morphological descriptions, comments, illustrations, photos, and a table. The study area includes the States of Ceará, Rio Grande do Norte, Paraíba, Pernambuco and Alagoas. The botanical material was collected, prepared, and deposited at the UFP herbarium. The collections of regional herbaria were analyzed. A total of 28 species were recorded belonging to seven genera, being Mandevilla (nine spp.), Prestonia (six spp.), Forsteronia (five spp.), Macropharynx, Odontadenia, Secondatia e Temnadenia (two spp. each). The State with the highest number of species was Pernambuco (21 spp.) and the most species-rich phytogeographic domain was the Atlantic Forest (21 spp.). Most species are climbers and vines (27 spp.), except Mandevilla dardanoi (subshrub) and M. tenuifolia (climber or erect subshrub). Ten species had their distribution expanded in the study area. The follicles of Mandevilla catimbauensis are illustrated by the first time.Um estudo taxonômico do grado Apocynoid (Apocynaceae) no Nordeste Oriental do Brasil é apresentado, e inclui uma chave de identificação, descrições morfológicas, comentários, ilustrações, fotos e uma tabela. A área de estudo inclui os Estados do Ceará, Rio Grande do Norte, Paraíba, Pernambuco e Alagoas. O material botânico foi coletado, preparado e depositado no herbário UFP. As coleções de herbários regionais foram analisadas. Um total de 28 espécies foi registro pertencente a sete gêneros: Mandevilla (nove spp.), Prestonia (seis spp.), Forsteronia (cinco spp.), Macropharynx, Odontadenia, Secondatia e Temnadenia (duas spp. cada). O Estado com maior número de espécies foi Pernambuco (21 spp.) e o domínio fitogeográfico mais rico foi a Mata Atlântica (21 spp.). A maioria das espécies é composta por trepadeiras e lianas (27 spp.), exceto Mandevilla dardanoi (subarbusto) e M. tenuifolia (trepadeira ou subarbusto ereto). Dez espécies tiveram sua distribuição ampliada na área de estudo. Os folículos de Mandevilla catimbauensis são ilustrados pela primeira vez

Perspectives of bilateral thoracic sympathectomy for treatment of heart failure

Surgical neuromodulation therapies are still considered a last resort when standard therapies have failed for patients with progressive heart failure (HF). Although a number of experimental studies have provided robust evidence of its effectiveness, the lack of strong clinical evidence discourages practitioners. Thoracic unilateral sympathectomy has been extensively studied and has failed to show significant clinical improvement in HF patients. Most recently, bilateral sympathectomy effect was associated with a high degree of success in HF models, opening the perspective to be investigated in randomized controlled clinical trials. In addition, a series of clinical trials showed that bilateral sympathectomy was associated with a decreased risk of sudden death, which is an important outcome in patients with HF. These aspects indicates that bilateral sympathectomy could be an important alternative in the treatment of HF wherein pharmacological treatment barely reaches the target dose

Laserterapia como tratamento complementar para pós cirúrgico odontológico: relato de caso

A laserterapia realizada com o laser de baixa potência tornou-se uma grande alternativa quando pensamos em terapia complementar, mais ainda quando falamos de cirurgia oral menor ou complexa. O presente relato de caso visa elucidar quanto a terapia fotodinâmica no pós-cirúrgico odontológico observando o controle da dor e edema no pós-operatório após exodontia de terceiro molar. O relato de caso é de paciente do gênero feminino, 27 anos de idade, que compareceu a clínica odontológica da Faculdade Metropolitana de Manaus (FAMETRO) relatando sintomatologia dolorosa na região de molares inferiores esquerdo. A paciente relatou que há mais ou menos sete anos sofria com o dente 38, mas não possuía condições financeiras para realizar o tratamento. Após a extração foi efetuada a primeira sessão de laserterapia aplicando um total de 6J de energia sendo dois pontos com 1J de energia na região cervical de cada face. Esse processo se repetiu por mais duas sessões com intervalos de 24 horas cada. Completado os 7 dias de pós-operatório a paciente relatou ter apresentado ausência de edema e alívio da sintomatologia dolorosa. Como conclusão, podemos observar que com este protocolo houve diminuição significativa da dor e edema, fotobioestimulação e retração da ferida

Ten Quick Tips for Harnessing the Power of ChatGPT/GPT-4 in Computational Biology

The rise of advanced chatbots, such as ChatGPT, has sparked curiosity in the scientific community. ChatGPT is a general-purpose chatbot powered by large language models (LLMs) GPT-3.5 and GPT-4, with the potential to impact numerous fields, including computational biology. In this article, we offer ten tips based on our experience with ChatGPT to assist computational biologists in optimizing their workflows. We have collected relevant prompts and reviewed the nascent literature in the field, compiling tips we project to remain pertinent for future ChatGPT and LLM iterations, ranging from code refactoring to scientific writing to prompt engineering. We hope our work will help bioinformaticians to complement their workflows while staying aware of the various implications of using this technology. Additionally, to track new and creative applications for bioinformatics tools such as ChatGPT, we have established a GitHub repository at https://github.com/csbl-br/awesome-compbio-chatgpt. Our belief is that ethical adherence to ChatGPT and other LLMs will increase the efficiency of computational biologists, ultimately advancing the pace of scientific discovery in the life sciences.Comment: 14 pages, 1 figur