Antiulcer Potential of the Ethanolic Extract of Aerva Persica Merrill Root in Rats

AbstractThe ethanol extract of the roots of Aerva persica (Burm f) Merrill (Amaranthaceae) was investigated to determine its antiulcer and in vivo antioxidant activities in albino Wistar rats. Ulcers were induced by ethanol and pylorus ligation. The extract was administered at the dose of 200mg/kg orally, p.o. for 15 consecutive days. The ulcer index of the ethanol extract was found to be significantly reduced compared with control animals. The effect was also assessed by determining the free acidity, pepsin activity, total carbohydrate (TC), and protein content (PK) in control, standard, and test group animals. The in vivo antioxidant activity was evaluated by determining the reduced glutathione level (GSH) and malondialdehyde (MDA) level in the tissue homogenates. The results reveal the significant reduction in the level of malondialdehyde and the increase in the level of reduced glutathione in the rats that received the ethanolic extract. Furthermore, histopathological studies have shown that pretreatment with the ethanolic extract of the roots of A persica reduces (100%) ethanol- and pylorus ligation-induced hemorrhagic necrosis in rats

Exploring Raw Safety Aspects in Aviation Industry

Aviation is the growing industry. Safety in the aviation industry is most important. Safety is affected by many factors such as environmental, economical, technical, and operational and many challenges are in the way of aviation safety to overcome from these hurdles .So this paper tried to explore the different safety aspects for the aviation industry. From the literature different research streams and research issues are discussed which affects the safety of the aviation industry. Keywords: Aviation Safety, Challenges, Safety Aspects, Environmental, Economical, Technica

PHYTOCHEMICAL SCREENING AND CHARACTERIZATION OF VOLATILE COMPOUNDS BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY FROM “NEPHROLEPIS EXALTATA”

Objective: Plants contain various types of phytochemicals with different solvent as per solvation properties, depending on their polarity. The goal of this analysis is to compare the effects of different solvents on the phytochemical profile and the characterization of different volatile bioactive compounds of Nephrolepis exaltata, a typical fern belonging to pteridophyte species. Methods: For the screening of phytochemical, a sequential extraction was carried out using different solvent systems namely methanol (MeOH), chloroform, carbon tetrachloride, hexane, and ethyl acetate (EtAc). A varied range of phytochemicals was found in the extracts. The volatile components were analyzed using the hyphenated technique gas chromatography-mass spectrometry (GC-MS). Results: All the extracts were found to be rich in alkaloids, whereas phenols and Phytosterols were extracted only in MeOH. The MeOH extract of the fern presented positive results for six phytochemical tests and the n-Hexane (nH) extract presented positive results for seven phytochemical tests. The present investigation on the plant N. exaltata aimed to prove that pteridophytes should have various kinds of bioactive phytochemicals and the selection of solvent for extraction of phytochemicals should be based on the target compounds. Conclusion: From the % yield of different extract, it can be concluded that some the bioactive phytochemicals are more soluble in more polar solvents such as MeOH, some are soluble in moderate solvents like EtAc and mostly non-polar organic molecules can be extracted using non-polar solvents like nH. The GC-MS characterization indicates the presence of different fatty compounds and sterols in the plant extract

Functional outcome of proximal tibial fracture treated surgically using locking compression plate

Background: Tibial plateau fractures are common intra-articular fractures, representing 1.2% of all fractures. These fractures are common in two age groups: as higher-energy fractures in younger patients and lower-energy fractures in elderly patients secondary to osteopenia. In the younger population, these injuries are associated with an increased incidence of complications like nonunion, infection, restriction of motion, and post-traumatic arthritis. The study aimed for final outcome of proximal tibial fracture using locking compression plate by minimally invasive percutaneous plate osteosynthesis (MIPPO).Methods: 30 cases of proximal tibial fractures were treated by using locking compression plate and studied from December 2015 to November 2017 in Department of Orthopaedics, Dr. S.N. Medical College associated group of Hospitals, Jodhpur.Results: All the selected 30 cases were followed up for 6 months. The average time for union of fracture was 21 weeks ranging from 18-24 weeks. Full weight bearing was not allowed until 12 weeks or complete fracture union. Partial immobilization was kept for 6 weeks in long knee brace. An average flexion was achieved upto0-1140. We observed 4 cases of postoperative complications that included 2 infections, one knee stiffness and one varus deformity.Conclusions: Surgical management of proximal tibia fractures with only lateral plating by MIPPO gave excellent reduction, rigid fixation to restore articular congruity and provides early motion to achieve optimal knee function and reducing post-traumatic osteoarthritis

Telemedicine Solution using Django

The average person usually don’t have much information about diseases related to symptoms they have and which doctor to visit for that disease. This causes a lot of wastage of time and money because they have to search doctor by doctor to get the right doctor and get an appointment with that doctor. Also not all doctors treat all diseases, this means just knowing your disease is not enough. Through this telemedicine solution we have tried to mitigate the inefficiency and delays in the system. Patients can get a basic idea of the possible disease they might have and a  list of  doctors suited to cure this disease is given as output to the patient. Then the patient can connect with doctors on a website

Recovering Shared Objects Without Stable Storage

This paper considers the problem of building fault-tolerant shared objects when processes can crash and recover but lose their persistent state on recovery. This Diskless Crash-Recovery (DCR) model matches the way many long-lived systems are built. We show that it presents new challenges, as operations that are recorded at a quorum may not persist after some of the processes in that quorum crash and then recover. To address this problem, we introduce the notion of crash-consistent quorums, where no recoveries happen during the quorum responses. We show that relying on crash-consistent quorums enables a recovery procedure that can recover all operations that successfully finished. Crash-consistent quorums can be easily identified using a mechanism we term the crash vector, which tracks the causal relationship between crashes, recoveries, and other operations. We apply crash-consistent quorums and crash vectors to build two storage primitives. We give a new algorithm for multi-writer, multi-reader atomic registers in the DCR model that guarantees safety under all conditions and termination under a natural condition. It improves on the best prior protocol for this problem by requiring fewer rounds, fewer nodes to participate in the quorum, and a less restrictive liveness condition. We also present a more efficient single-writer, single-reader atomic set - a virtual stable storage abstraction. It can be used to lift any existing algorithm from the traditional Crash-Recovery model to the DCR model. We examine a specific application, state machine replication, and show that existing diskless protocols can violate their correctness guarantees, while ours offers a general and correct solution

On-line monitoring of methane in sewer air

Methane is a highly potent greenhouse gas and contributes significantly to climate change. Recent studies have shown significant methane production in sewers. The studies conducted so far have relied on manual sampling followed by off-line laboratory-based chromatography analysis. These methods are labor-intensive when measuring methane emissions from a large number of sewers, and do not capture the dynamic variations in methane production. In this study, we investigated the suitability of infrared spectroscopy-based on-line methane sensors for measuring methane in humid and condensing sewer air. Two such sensors were comprehensively tested in the laboratory. Both sensors displayed high linearity (R2 > 0.999), with a detection limit of 0.023% and 0.110% by volume, respectively. Both sensors were robust against ambient temperature variations in the range of 5 to 35°C. While one sensor was robust against humidity variations, the other was found to be significantly affected by humidity. However, the problem was solved by equipping the sensor with a heating unit to increase the sensor surface temperature to 35°C. Field studies at three sites confirmed the performance and accuracy of the sensors when applied to actual sewer conditions, and revealed substantial and highly dynamic methane concentrations in sewer air

In Vitro Antioxidant Activity of root extracts of Heliotropium eichwaldi Stued. ex DC

ABSTRACT In vitro antioxidant activity of methanolic and aqueous root extracts of Heliotropium eichwaldi Stued. ex DC. was determined by DPPH free radical scavenging assay and hydrogen peroxide scavenging activity. The extract revealed marked activity as a radical scavenger in a study indicating that extracts have ability to donate hydrogen. The absorption is stoichiometric in respect to the number of electrons taken up. Concentration of 0.1 mg/ml of methanolic extract (HME) and aqueous root extract (HAE) of Heliotropium eichwaldi exhibited 62.73% and 57.18% DPPH scavenging activity. The antioxidant activity of these extracts towards hydrogen peroxide was also reported. A 76.94% and 70.79% of inhibition of hydrogen peroxide was observed with HME and HAE respectively, when compared with control, at a concentration of 0.1 mg/ml using ascorbic acid as standard and positive control on analysis with UV-Visible Spectrophotometer. The results conclude that the extracts are a potential source of antioxidants of natural origin and may be a candidate for treating pathologies related to free radical oxidation due to its overall antioxidant effect in scavenging free radicals and active oxygen species

Effect of Sonication Parameters on Mechanical Properties of In-situ Amine Functionalized Multiple Layer Graphene/Epoxy Nanocomposites

985-989In this investigation, combined effects of various sonication time and power on dispersion of 0.75 wt.% In-situ amine functionalized multi-layer Graphene (AF-MGL) in polymer matrix were studied. To ensure proper dispersion of AF-MGL in the epoxy matrix, sonication times of 10, 40, 70 min and powers of 20, 40, 60 W were used. The tensile test results indicate an initial increase in tensile modulus at smaller sonication time and then decrease for more sonication times. The highest tensile modulus and tensile strength were obtained at 40 W, 40 min and at 20 W, 40 min respectively. In order to classify the AF-MGL dispersion status, a scanning electron microscope (SEM) was used. With increased sonicity time and strength, dispersion has been noticed