233 research outputs found
Generation of circumferential velocity contours associated with pulsed point suction on a rotating disk
Numerous experimental studies were conducted on the steady, three-dimensional boundary layer over a disk rotating at constant angular speed in an otherwise undisturbed fluid. The subject flow geometry is of interest because it provides a relatively simple way to study the cross-flow instability phenomenon which occurs in three-dimensional boundary layers, as on swept wings. This flow instability results in the formation of a stationary spiral vortex flow field over the disk, as shown by Wilkinson and Malik. Using a hot-wire probe, the spatial wave pattern of stationary vortices, which filled the entire circumference of the disk was mapped. The subject flow instability caused transition-to-turbulent flow as the periphery of the disk was approached. The effect on receptivity and transition of discrete disturbance modes, such as three-dimensional toughness elements and acoustic excitation was investigated. The present study (an extension of the work of Wilkinson and Malik) is focused on the effect of pulsed point suction on flow instability and transition, and consequently, on the classical stationary vortical flow pattern
Boundary-layer measurements on a high Reynolds number three-element airfoil
An experimental investigation is being conducted to evaluate the boundary layer associated with a two-dimensional three-element single-flap airfoil at high Reynolds numbers. The present measurements are being made in the Langley Low-Turbulence (centerline turbulence intensity level is 0.034 percent at a Mach number of 0.2 and a total pressure of 60 psia) Pressure Tunnel (LTPT). The LTPT is a closed-circuit wind tunnel with a test section which is 3 ft wide, 7.5 ft high, and 7.5 ft long. Operating total pressure for the LTPT varies from 10 atmospheres to near-vacuum conditions. Tests are being conducted at a Mach number of 0.2 and Reynolds numbers (based on chord length) of 5, 9, and 16 million. Measurements include boundary-layer velocity surveys at several chordwise locations and surface skin-friction measurements using Preston tubes
Jet vortex generators for turbulent flow separation control
A parametric study was performed with jet vortex generators to determine their effectiveness in controlling flow separation associated with low speed turbulent flow over a two dimensional rearward-facing ramp. Results indicate that flow separation control can be accomplished with the level of control achieved being a function of jet speed, jet orientation (with respect to the free stream direction), and orifice pattern (double row of jets vs. single row). Compared to slot blowing, jet vortex generators can provide an equivalent level of flow control over a larger spanwise region (for constant jet flow area and speed)
An Experimental Investigation of Wall-Cooling Effects on Hypersonic Boundary-Layer Stability in a Quiet Wind Tunnel
One of the primary reasons for developing quiet tunnels is for the investigation of high-speed boundary-layer stability and transition phenomena without the transition-promoting effects of acoustic radiation from tunnel walls. In this experiment, a flared-cone model under adiabatic- and cooled-wall conditions was placed in a calibrated, 'quiet' Mach 6 flow and the stability of the boundary layer was investigated using a prototype constant-voltage anemometer. The results were compared with linear-stability theory predictions and good agreement was found in the prediction of second-mode frequencies and growth. In addition, the same 'N=10' criterion used to predict boundary-layer transition in subsonic, transonic, and supersonic flows was found to be applicable for the hypersonic flow regime as well. Under cooled-wall conditions, a unique set of continuous spectra data was acquired that documents the linear, nonlinear, and breakdown regions associated with the transition of hypersonic flow under low-noise conditions
Non-linear boundary-layer receptivity due to distributed surface roughness
The process by which a laminar boundary layer internalizes the external disturbances in the form of instability waves is known as boundary-layer receptivity. The objective of the present research was to determine the effect of acoustic excitation on boundary-layer receptivity for a flat plate with distributed variable-amplitude surface roughness through measurements with a hot-wire probe. Tollmien-Schlichting (T-S) mode shapes due to surface-roughness receptivity have also been determined, analyzed, and shown to be in agreement with theory and other experimental work. It has been shown that there is a linear relationship between the surface roughness and receptivity for certain roughness configurations with constant roughness wavelength. In addition, strong nonlinear receptivity effects exist for certain surface roughness configurations over a band where the surface roughness and T-S wavelength are matched. The results from the present experiment follow the trends predicted by theory and other experimental work for linear receptivity. In addition, the results show the existence of nonlinear receptivity effects for certain combinations of surface roughness elements
A quiet tunnel investigation of hypersonic boundary-layer stability over a cooled, flared cone
A flared-cone model under adiabatic and cooled-wall conditions was placed in a calibrated, low-disturbance Mach 6 flow and the stability of the boundary layer was investigated using a prototype constant-voltage anemometer. The results were compared with linear-stability theory predictions and good agreement was found in the prediction of second-mode frequencies and growth. In addition, the same 'N = 10' criterion used to predict boundary-layer transition in subsonic, transonic, and supersonic flows under low freestream noise conditions was found to be applicable for the hypersonic flow regime as well. Under cooled-wall conditions, a unique set of spectral data was acquired that documents the linear, nonlinear, and breakdown regions associated with the transition of hypersonic flow under low-noise conditions
ESMD Space Grant Faculty Report
The strength of the Exploration Systems Mission Directorate ESMD Faculty Project lies in its ability to meet National Aeronautics Space Administration NASA's Strategic Educational Outcome 1 by developing a sustainable and long-term integration of student involvement at academic institutions with all NASA Centers. This outcome is achieved by a three-fold approach: 1) by collecting Senior Design projects pertaining to Constellation work performed at each of the ten NASA Centers, 2) by engaging students at Minority Serving Institutions in the art of systems engineering and systems design of technologies required for space exploration, and 3) by identifying potential internships at each Center relative to exploration that provide students who are supported by their institutional Space Grant to engage in on-going mission-level and explorative systems designs. The objectives of the ESMD Faculty Project are to: 1. Aid the Centers (both Education Offices and associated technical organizations) in providing relevant opportunities for the ESMD Space Grant Program to support student and faculty in Senior Design projects 2. Enable better matches between the ESMD work required and what the Space Grant Consortia can do to effectively contribute to NASA programs 3. Provide the Space Grant Consortia an opportunity to strengthen relations with the NASA Centers 4. Develop better collective understanding of the U.S. Space Exploration Policy by the Center, Space Grant, faculty, Education Office, and students 5. Enable Space Grant institution faculty to better prepare their students to meet current and future NASA needs 6. Enable the Center Education Offices to strengthen their ties to their technical organizations and Space Grant Consortia 7. Aid KSC in gaining a greater and more detailed understanding of each of the Center activities Senior Design projects are intended to stimulate undergraduate students on current NASA activities related to lunar, Mars, and other planetary missions and to bring out innovative and novel ideas that can be used to complement those currently under development at respective NASA Centers. Additionally, such academic involvement would better the prospects for graduating seniors to pursue graduate studies and to seek careers in the space industry with a strong sense for systems engineering and understanding of design concepts. Internships, on the other hand, are intended to provide hands-on experience to students by engaging them in diverse state-of-the-art technology development, prototype bread-boarding, computer modeling and simulations, hardware and software testing, and other activities that provide students a strong perspective of NASA's vision and mission in enhancing the knowledge of Earth and space planetary sciences. Ten faculty members, each from a Space Grant Consortium-affiliated university, worked at ten NASA Centers for five weeks between June 2 and July 3, 2008. The project objectives listed above were achieved. In addition to collecting data on Senior Design ideas and identifying possible internships that would benefit NASA/ESMD, the faculty fellows promoted and collected data when required for other ESMD-funded programs and helped the Center's Education Office, as,needed.
High hospital research participation and improved colorectal cancer survival outcomes: a population-based study
Objective: In 2001, the National Institute for Health Research (NIHR) Cancer Research Network (NCRN) was established, leading to a rapid increase in clinical research activity across the English NHS. Using colorectal cancer (CRC) as an example, we test the hypothesis that high, sustained hospital-level participation in interventional clinical trials improves outcomes for all CRC patients managed in those research-intensive hospitals.
Design: Data for patients diagnosed with CRC in England in 2001-2008 (n=209,968) were linked with data on accrual to NCRN CRC studies (n=30,998). Hospital Trusts were categorised by the proportion of patients accrued to interventional studies annually. Multivariable models investigated the relationship between 30-day post-operative mortality and five-year survival and the level and duration of study participation.
Results: Most of the Trusts achieving high participation were district general hospitals and the effects were not limited to cancer “centres of excellence”, although such centres do make substantial contributions. Patients treated in Trusts with high research participation (≥16%) in their year of diagnosis had lower post-operative mortality (p<0.001) and improved survival (p<0.001) after adjustment for casemix and hospital-level variables. The effects increased with sustained research participation, with a reduction in post-operative mortality of 1.5% (6.5% to 5%, p<2.2*10-6) and an improvement in survival (p<10 19; 5-year difference: 3.8% (41.0% to 44.8%)) comparing high participation for ≥4 years with 0 years.
Conclusion: There is a strong independent association between survival and participation in interventional clinical studies for all CRC patients treated in the hospital, not only study participants. Improvement precedes and increases with the level and years of sustained participation
How can clinical research improve European health outcomes in cancer?
We review the mechanisms by which clinical cancer research can improve health outcomes and argue that this should be central to the development of policy. Recent series of major international studies have analysed large, often nationwide, datasets for cancer patient outcomes and participation in clinical research. They have evaluated and quantified the impact of new evidence generated by randomised controlled trials on cancer survival. They show a strong and probably causal relationship between the participation in clinical research in hospitals and the outcomes for patients with the disease under study in those hospitals. Also, institutions that are active in clinical trials appear to take up well evidenced innovations more rapidly than those which are not so engaged. Further work is necessary to confirm and examine the generalisability of these findings but we argue that all of these mechanisms are likely to lead to improved outcomes for patients as a consequence of the conduct of clinical research. The size of the benefit appears to be substantial and an active programme to promote clinical research across cancer care systems should be a part of National Cancer Plans and Cancer Control Strategies
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