Post common envelope binaries from SDSS. II : identification of 9 close binaries with VLT/FORS2

Context. Post common envelope binaries (PCEBs) consisting of a white dwarf and a main sequence star are ideal systems to use to calibrate current theories of angular momentum loss in close compact binary stars. The potential held by PCEBs for further development of close binary evolution could so far not be exploited due to the small number of known systems and the inhomogeneity of the sample. The Sloan Digital Sky Survey is changing this scene dramatically, as it is very efficient in identifying white dwarf/main sequence (WDMS) binaries, including both wide systems whose stellar components evolve like single stars and − more interesting in the context of close binary evolution − PCEBs. Aims. We pursue a large-scale follow-up survey to identify and characterise the PCEBs among the WDMS binaries that have been found with SDSS. We use a two-step strategy with the identification of PCEBs among WDMS binaries in the first phase and orbital period determinations in the second phase. Here we present first results of our ESO-VLT/FORS2 pilot study that targets the identification of the PCEBs among the fainter (g >∼18.5) SDSSWDMS binaries. Methods. From published SDSS catalogues we selected 26 WDMS binaries to be observed with ESO-VLT/FORS2 in service mode. The design of the observations was to get two spectra per object separated by at least one night.We used the Na I λλ 8183.27, 8194.81 doublet to measure radial velocity variations of our targets and a spectral decomposition/fitting technique to determine the white dwarf effective temperatures and surface gravities, masses, and secondary star spectral types for all WDMS binaries in our sample. Results. Among the 26 observed WDMS binaries, we find 9 strong PCEB candidates showing clear (≥3σ) radial velocity variations, and we estimate the fraction of PCEBs among SDSS WDMS binaries to be ∼35 ± 12%. We find indications of a dependence of the relative number of PCEBs among SDSSWDMS binaries on the spectral type of the secondary star. These results are subject to small number statistics and need to be confirmed by additional observations. Using Magellan-Clay/LDSS3, we measured the orbital periods of two PCEB candidates, SDSS J1047+0523 and SDSS J1414–0132, to be 9.17 h and 17.48 h, respectively. Conclusions. This pilot study demonstrates that our survey is highly efficient in identifying PCEBs among the SDSSWDMS binaries, and it will indeed provide the observational parameters that are needed to constrain the theoretical models of close binary evolution

Phyllosphere microbiology with special reference to diversity and plant genotype

The phyllosphere represents the habitat provided by the aboveground parts of plants, and on a global scale supports a large and complex microbial community. Microbial interactions in the phyllosphere can affect the fitness of plants in natural communities, the productivity of agricultural crops, and the safety of horticultural produce for human consumption. The structure of phyllosphere communities reflects immigration, survival and growth of microbial colonists, which is influenced by numerous environmental factors in addition to leaf physico-chemical properties. The recent use of culture-independent techniques has demonstrated considerable previously unrecognized diversity in phyllosphere bacterial communities. Furthermore, there is significant recent evidence that plant genotype can play a major role in determining the structure of phyllosphere microbial communities. The main aims of this review are: (i) to discuss the diversity of phyllosphere microbial populations; (ii) to consider the processes by which microbes colonize the phyllosphere; (iii) to address the leaf characteristics and environmental factors that determine the survival and growth of colonists; (iv) to discuss microbial adaptations that allow establishment in the phyllosphere habitat and (v) to evaluate evidence for plant genotypic control of phyllosphere communities. Finally, we suggest approaches and priority areas for future research on phyllosphere microbiology

High angular resolution integral-field spectroscopy of the Galaxy's nuclear cluster: a missing stellar cusp?

We report on the structure of the nuclear star cluster in the innermost 0.16 pc of the Galaxy as measured by the number density profile of late-type giants. Using laser guide star adaptive optics in conjunction with the integral field spectrograph, OSIRIS, at the Keck II telescope, we are able to differentiate between the older, late-type ($\sim$ 1 Gyr) stars, which are presumed to be dynamically relaxed, and the unrelaxed young ($\sim$ 6 Myr) population. This distinction is crucial for testing models of stellar cusp formation in the vicinity of a black hole, as the models assume that the cusp stars are in dynamical equilibrium in the black hole potential. Based on the late-type stars alone, the surface stellar number density profile, $\Sigma(R) \propto R^{-\Gamma}$, is flat, with $\Gamma = -0.27\pm0.19$. Monte Carlo simulations of the possible de-projected volume density profile, n(r) $\propto r^{-\gamma}$, show that $\gamma$ is less than 1.0 at the 99.73 % confidence level. These results are consistent with the nuclear star cluster having no cusp, with a core profile that is significantly flatter than predicted by most cusp formation theories, and even allows for the presence of a central hole in the stellar distribution. Of the possible dynamical interactions that can lead to the depletion of the red giants observable in this survey -- stellar collisions, mass segregation from stellar remnants, or a recent merger event -- mass segregation is the only one that can be ruled out as the dominant depletion mechanism. The lack of a stellar cusp around a supermassive black hole would have important implications for black hole growth models and inferences on the presence of a black hole based upon stellar distributions.Comment: 35 pages, 5 tables, 12 figures, accepted by Ap

Effects of combined administration of FK 506 and the purine biosynthesis inhibitors mizoribine or mycophenolic acid on lymphocyte DNA synthesis and T cell activation molecule expression in human mixed lymphocyte cultures

Our objective was to obtain new information on the in vitro antilymphocytic action of the cytokine synthesis inhibitor FK 506 and the purine biosynthesis inhibitors mycophenolic acid (MPA; the active moiety of RS61443) and mizoribine (MZB) when used alone or in combination. When added at the initiation of six-day human mixed lymphocyte cultures (MLC), FK 506, MPA or MZB exhibited dose-dependent inhibition of T-lymphocyte DNA synthesis. FK 506, however, was 100-fold more potent than MPA, and 10000-fold more potent than MZB. Combination of FK 506 with either MPA or MZB, each at suboptional concentrations, produced no more than additive inhibitory effects on 3H thymidine incorporation. Two-colour flow cytometric analysis of lymphocytes revealed that none of the drugs affected cell surface activation molecule expression (CD25 = IL-2R 55 kD α-chain, HLA-DR or CD71 = transferrin receptor [TR]) on allostimulated CD4+ or CD8+ cells harvested at three days of culture. By day six, however, all three agents, at levels which markedly inhibited proliferation, suppressed the expression of activation markers on both CD4+ and CD8+ cells. Also at day six, inhibition of activation molecule expression on CD4+ cells was achieved with the combination of FK 506 and either MPA or MZB at concentrations which, on their own, were ineffective. These data provide new, additional information on the in vitro antilymphocytic action of FK 506, MPA and MZB when used alone and in combination. © 1993

Clinical nutrition in primary care: An evaluation of resident physicians' attitudes and self-perceived proficiency.

There is little information regarding the impact of clinical nutrition training among medical residents. We aimed to evaluate the attitudes, self-perceived proficiency and knowledge of Swiss residents regarding clinical nutrition. Cross-sectional study conducted between June and September 2014 in two medical education facilities located in Lausanne, Switzerland. Attitudes, self-perceived proficiency and knowledge regarding clinical nutrition were assessed by questionnaire. Of the 88 internal medicine residents queried, 44 (50% response rate, 25 women, mean age 34 ± 4 years) answered the questionnaire. Three quarters of the residents were trained in Switzerland and one third reported receiving some training in clinical nutrition. Seven out of ten (70.5%) residents agreed that all doctors should know how to provide nutrition-based assessment, no matter what their specialty. Conversely, only one out of ten (11.4%) felt that physicians were adequately trained. No differences were found between genders or country of training regarding the answers provided. Residents in Lausanne perceive clinical nutrition in primary care as a priority but lack the confidence and training to effectively use clinical nutrition in their daily practice

Statistical-Mechanical Measure of Stochastic Spiking Coherence in A Population of Inhibitory Subthreshold Neurons

By varying the noise intensity, we study stochastic spiking coherence (i.e., collective coherence between noise-induced neural spikings) in an inhibitory population of subthreshold neurons (which cannot fire spontaneously without noise). This stochastic spiking coherence may be well visualized in the raster plot of neural spikes. For a coherent case, partially-occupied "stripes" (composed of spikes and indicating collective coherence) are formed in the raster plot. This partial occupation occurs due to "stochastic spike skipping" which is well shown in the multi-peaked interspike interval histogram. The main purpose of our work is to quantitatively measure the degree of stochastic spiking coherence seen in the raster plot. We introduce a new spike-based coherence measure $M_s$ by considering the occupation pattern and the pacing pattern of spikes in the stripes. In particular, the pacing degree between spikes is determined in a statistical-mechanical way by quantifying the average contribution of (microscopic) individual spikes to the (macroscopic) ensemble-averaged global potential. This "statistical-mechanical" measure $M_s$ is in contrast to the conventional measures such as the "thermodynamic" order parameter (which concerns the time-averaged fluctuations of the macroscopic global potential), the "microscopic" correlation-based measure (based on the cross-correlation between the microscopic individual potentials), and the measures of precise spike timing (based on the peri-stimulus time histogram). In terms of $M_s$, we quantitatively characterize the stochastic spiking coherence, and find that $M_s$ reflects the degree of collective spiking coherence seen in the raster plot very well. Hence, the "statistical-mechanical" spike-based measure $M_s$ may be used usefully to quantify the degree of stochastic spiking coherence in a statistical-mechanical way.Comment: 16 pages, 5 figures, to appear in the J. Comput. Neurosc