2,351 research outputs found
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Identification of the expressome by machine learning on omics data.
Accurate annotation of plant genomes remains complex due to the presence of many pseudogenes arising from whole-genome duplication-generated redundancy or the capture and movement of gene fragments by transposable elements. Machine learning on genome-wide epigenetic marks, informed by transcriptomic and proteomic training data, could be used to improve annotations through classification of all putative protein-coding genes as either constitutively silent or able to be expressed. Expressed genes were subclassified as able to express both mRNAs and proteins or only RNAs, and CG gene body methylation was associated only with the former subclass. More than 60,000 protein-coding genes have been annotated in the reference genome of maize inbred B73. About two-thirds of these genes are transcribed and are designated the filtered gene set (FGS). Classification of genes by our trained random forest algorithm was accurate and relied only on histone modifications or DNA methylation patterns within the gene body; promoter methylation was unimportant. Other inbred lines are known to transcribe significantly different sets of genes, indicating that the FGS is specific to B73. We accurately classified the sets of transcribed genes in additional inbred lines, arising from inbred-specific DNA methylation patterns. This approach highlights the potential of using chromatin information to improve annotations of functional genes
Influencing Choices by Changing Beliefs: A Logical Theory of Influence, Persuasion, and Deception
Wemodelpersuasion,viewedasadeliberateactionthroughwhichan agent (persuader) changes the beliefs of another agent’s (persuadee). This notion of persuasion paves the way to express the idea of persuasive influence, namely inducing a change in the choices of the persuadee by changing her beliefs. It allows in turns to express different aspects of deception. To this end, we propose a logical framework that enables expressing actions and capabilities of agents, their mental states (desires, knowledge and beliefs), a variety of agency operators as well as the connection between mental states and choices. Those notions, once combined, enable us to capture, the notion of influence, persuasion and deception, as well as their relation
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A Contemporary Approach to the Design of Jewelry
Personal adornment is one of the oldest and most fundamental needs of man. Superstition, awareness of social position and the desire for secure investment are some of the fundamental urges behind man's desire to adorn his person. Jewelry and personal adornment have been invested with magic, symbolic meanings and commemorative values. Contemporary artists have attempted to emphasize the aesthetic value of jewelry, demanding a reexamination of conventional attitudes toward jewelry; designing forms which are an expression of their insight into life rather than an article of value mainly for the precious materials from which it is made.
A variety of techniques have been used to create the jewelry in this collection. One collar is silver and gold; the pieces cut from sheet silver, flat silver wire, and gold filled wire. Another collar is copper woven mesh flooded with silver, linked with silver jump rings and embellished with silver domes. A large breast plate pendant is an interpretation of the filigree technique, using silver rings in a variety of sizes to form a large butterfly shape.
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Temperature dependence of single-particle properties in nuclear matter
The single-nucleon potential in hot nuclear matter is investigated in the
framework of the Brueckner theory by adopting the realistic Argonne V18 or
Nijmegen 93 two-body nucleon-nucleon interaction supplemented by a microscopic
three-body force. The rearrangement contribution to the single-particle
potential induced by the ground state correlations is calculated in terms of
the hole-line expansion of the mass operator and provides a significant
repulsive contribution in the low-momentum region around and below the Fermi
surface. Increasing temperature leads to a reduction of the effect, while
increasing density makes it become stronger. The three-body force suppresses
somewhat the ground state correlations due to its strong short-range repulsion,
increasing with density. Inclusion of the three-body force contribution results
in a quite different temperature dependence of the single-particle potential at
high enough densities as compared to that adopting the pure two-body force. The
effects of three-body force and ground state correlations on the nucleon
effective mass are also discussed.Comment: 14 pages, 5 figure
Robust Aeroelastic Optimisation of Composite Plate Wings Subject to Ply Orientation Uncertainty
Carrying capacity and goat botanical diet composition in an arid ecosystem, Lavalle, Argentina
8 págs, 1 tabla.-- Comunicación presentada a la XLV Reunión Científica de la Sociedad Española para el Estudio de los Pastos: "Producciones agroganaderas: gestión eficiente y conservación del medio natural" (Gijón, 28 de mayo al 3 de junio de 2005).[ES] El trabajo se llevó a cabo en el departamento de Lavalle, Mendoza, Argentina. Las unidades de pastos, más importantes desde el punto de vista forrajero son: Algarrobal de Prosopis flexuosa; Matorral con Atriplex lampa (zampal); Matorral con Tricomaria usillo
(usillar); Matorral degradado con Larrea cuneifolia (jarillal) y Medanal. Los objetivos del estudio fueron estimar la capacidad sustentadora de las diferentes unidades y la composición botánica de la ingesta de los caprinos. La estimación de dicha capacidad, expresada en hectáreas por Unidades Ganadera Caprinas (ha UGC–1), se realizó mediante el método de Point Quadrat modificado para el Monte. Y por medio del análisis microhistológico de heces se determinó la composición estacional de la ingesta.Los valores medios anuales de capacidad sustentadora fueron: Algarrobal, 1,2;
Zampal, 1,7; Usillar, 3,5; Jarillal, 5,8 y Médanos, 4,3 ha UGC-1. La composición de la
ingesta varió durante las estaciones, observándose una predominancia de las especies arbustivas, las gramíneas perennes aparecieron en muy baja frecuencia en todas las estaciones. El Algarrobal y el Zampal son las unidades de mayor importancia forrajera, presentando receptividades ganaderas más altas y una oferta forrajera más estable a lo largo del año, respecto del resto de las unidades de pastos analizadas.[EN] The work was carried out in the department of Lavalle, Mendoza, Argentina. The units of pastures, more important from the forage matter are: Algarrobal of Prosopis flexuosa; Shrubland with Atriplex lampa (zampal); Shrubland with Tricomaria usillo (usillar); Shrubland degraded with Larrea cuneifolia (jarillal) and Dunes. The aims of the study were to estimate the carrying capacity of the different units and the botanical composition of goat diets. The carrying capacity, expressed in hectares by Units Goat (ha UG-1), was measured by the method of Point Quadrat modified for Monte and the seasonal
botanical composition of goat diets, was determined by microhistological analysis of
faeces. The annual average values of carrying capacity were: Algarrobal, 1.2; Zampal, 1.7; Usillar, 3.5; Jarillal, 5.8 and Dunes, 4.3 ha UG-1. The composition of the diet varied during the seasons, the predominance of the shrubs species were observed, the perennial grass appeared in low frequency in all the seasons. The Algarrobal and the Zampal are the units
of greater forage importance, where forage receptivity are higher and with more stable
production throughout the year, respect to the others units of pastures analyzed.Peer reviewe
Bisphenol A‐associated alterations in the expression and epigenetic regulation of genes encoding xenobiotic metabolizing enzymes in human fetal liver
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106679/1/em21823.pd
Isospin splitting of the nucleon mean field
The isospin splitting of the nucleon mean field is derived from the Brueckner
theory extended to asymmetric nuclear matter. The Argonne V18 has been adopted
as bare interaction in combination with a microscopic three body force. The
isospin splitting of the effective mass is determined from the
Brueckner-Hartree-Fock self-energy: It is linear acording to the Lane ansatz
and such that for neutron-rich matter. The symmetry potential
is also determined and a comparison is made with the predictions of the
Dirac-Brueckner approach and the phenomenological interactions. The theoretical
predictions are also compared with the empirical parametrizations of neutron
and proton optical-model potentials based on the experimental nucleon-nucleus
scattering and the phenomenological ones adopted in transport-model simulations
of heavy-ion collisions. The direct contribution of the rearrangement term due
to three-body forces to the single particle potential and symmetry potential is
discussed.Comment: 8 pages, 10 figure
The baryonic Y-shape confining potential energy and its approximants
We discuss the validity of replacing the complicated three-body confinement
operator of the Y string junction type by three kinds of approximation which
are numerically much simpler to handle: a one-body operator with the junction
point at the centre of mass, a two-body operator corresponding to half the
perimeter of the triangle formed by the three particles, and the average of
both. Two different approaches for testing the quality of the approximations
are proposed: a geometrical treatment based on the comparison of the potential
energy strengths for the various inter quark distances, and a dynamical
treatment based on the comparison of the corresponding effective string
tensions using a hyperspherical approach. Both procedures give very similar
results. It is shown how to simulate the genuine string junction operator by
the approximations proposed above. Exact three-body calculations are presented
in order to compare quantitatively the various approximations and to confirm
our analysis.Comment: 28 pages, 5 figures, submitted to EPJ
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