48 research outputs found

    Jaque a la desigualdad. El ajedrez educativo y competitivo en Arag贸n desde una perspectiva de g茅nero

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    En el presente trabajo se describe la situaci贸n actual del ajedrez educativo y competitivo en Arag贸n desde una perspectiva de g茅nero. M谩s concretamente, se analiza la aplicaci贸n del Programa de Ajedrez en la Escuela en diferentes centros educativos y los datos aportados por la Federaci贸n Aragonesa de Ajedrez. Para ello, se investigan los beneficios del ajedrez en los jugadores, as铆 como las razones y estereotipos que pueden influenciar el abandono femenino del ajedrez. Para aproximarnos a la realidad se han realizado 5 entrevistas a diferentes agentes del mundo del ajedrez para conocer su punto de vista sobre la situaci贸n actual del ajedrez a nivel educativo y competitivo. Como resultado, se han obtenido una serie de puntos en com煤n en todos o muchos de los participantes, como por ejemplo las posibilidades que ofrece el ajedrez a nivel educativo como herramienta y a nivel competitivo como otro deporte que puede ser 煤til para el desarrollo de los ni帽os. Como conclusi贸n, se establece una relaci贸n entre el curr铆culo y el ajedrez, es decir, las potencialidades que ofrece este para la introducci贸n del ajedrez en las escuelas.<br /

    Assessment of a wide array of contaminants of emerging concern in a Mediterranean water basin (Guadalhorce river, Spain): Motivations for an improvement of water management and pollutants surveillance

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    This study investigates the occurrence and distribution of 185 organic contaminants (regulated pollutants and contaminants of emerging concern; CECs) in surface and groundwater of the Guadalhorce River basin (southern Spain) providing the most detailed dataset regarding organic pollution presented so far in this area. Up to 63 contaminants were detected in a monitoring campaign conducted in March 2016. Most contaminants were detected more frequently in surface water where they generally present higher concentrations suggesting the prevalence of wastewater discharges into streams as the main pollutant sources. In general, hydrophobic CECs presented the highest frequencies of detection and concentrations, which can be a consequence of several factors: (1) hydrophobic compounds show a higher retardation factor, which result, along with a continuous contaminant input, in a widespread and homogeneous distribution. In contrast, hydrophilic contaminants are more easily transported by water flows towards the lower basin and potentially accumulate as driven by groundwater flow and because of low renewal rates in the detrital aquifers caused by re-pumping and irrigation return flows in agricultural lands; (2) hydrophobic CECs studied in this research are mainly personal care products and organophosphate esters flame retardants and plasticizers, which are present in many different products and are used in large amounts; Also, (3) use of biosolids (reclaimed sewer sludge) as fertilizer for crops is potentially an additional diffuse source of organic pollutants in the study area contributing to a widespread distribution, especially for hydrophobic compounds. Obtained results highlight the need to better define the potential risk of non-regulated contaminants in water resources as well as the great impact of untreated wastewater discharges. (c) 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

    M茅todos diagn贸sticos de la infecci贸n por Helicobacter Pylori en Huesca

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    La dispepsia es patolog铆a frecuente en el 谩mbito de la atenci贸n primaria. Existen estrategias, para manejo de pacientes j贸venes con dispepsia, basadas en diagn贸stico previo de infecci贸n por Helicobacter pylori(HP) mediante un test no invasivo. Nuestro estudio revisa la eficacia de m茅todos diagn贸sticos en situaci贸n de pr谩ctica cl铆nica habitual en Hospital de Huesca. Es un estudio de observaci贸n descriptivo transversal prospectivo de pacientes ambulatorios con indicaci贸n de gastroscopia. Las pruebas utilizadas fueron invasivas (cultivo, estudio histol贸gico de antro y cuerpo g谩strico y test de ureasa) y no invasivas (test del aliento con urea-13C y serolog铆a-ELISA). La prueba de aliento es muy fiable en nuestro medio para el diagn贸stico de HP, por su alt铆sima sensibilidad y especificidad absoluta; comparada con las otras pruebas, es el mejor m茅todo diagn贸stico. La estrategia "prueba y tratamiento" en pacientes con dispepsia, sin s铆ntomas de alarma y que no toman antiinflamatorios se puede recomendar en esta 谩rea

    Prognostic role of host cyclooxygenase and cytokine genotypes in a caucasian cohort of patients with gastric adenocarcinoma

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    Background: Genetic factors influencing the prognosis of gastric adenocarcinoma (GAC) are not well known. Given the relevance of cytokines and other pro-inflammatory mediators in cancer progression and invasiveness, we aimed to assess the prognostic role of several functional cytokine and cyclooxygenase gene polymorphisms in patients with GAC. Methodology: Genomic DNA from 380 Spanish Caucasian patients with primary GAC was genotyped for 23 polymorphisms in pro-inflammatory (IL1B, TNFA, LTA, IL6, IL12p40), anti-inflammatory (IL4, IL1RN, IL10, TGFB1) cytokine, and cyclooxygenase (PTGS1 and PTGS2) genes by PCR, RFLP and TaqMan assays. Clinical and histological information was collected prospectively. Survival curves were estimated by the Kaplan-Meier method and compared using the log rank test. Outcome was determined by analysis of Cox proportional hazards, adjusting for confounding factors. Results: The median follow-up period and median overall survival (OS) time were 9.9 months (range 0.4-120.3) and 10.9 months (95% CI: 8.9-14.1), respectively. Multivariate analysis identified tumor stages III (HR, 3.23; 95% CI:2-5.22) and IV (HR, 5.5; 95% CI: 3.51-8.63) as independent factors associated with a significantly reduced OS, whereas surgical treatment (HR: 0.44; 95%CI: 0.3-0.6) was related to a better prognosis of the disease. Concerning genetic factors, none of the 23 polymorphisms evaluated in the current study did influence survival. Moreover, no gene-environment interactions on GAC prognosis were observed. Conclusions: Our results show that, in our population, the panel of selected pro- and anti-inflammatory cytokine, and cyclooxygenase gene polymorphisms are not relevant in determining the prognosis of gastric adenocarcinoma. 漏 2012 Garc铆a-Gonz谩lez et al.This study was supported by the Spanish >Fondo de Investigaciones Sanitarias> (grants PI05/0405 and PS09/00213), and Instituto de Salud Carlos III (CIBER de enfermedades hepaticas y digestivas).Peer Reviewe
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