1,324 research outputs found
MIMO-OFDM Based Energy Harvesting Cooperative Communications Using Coalitional Game Algorithm
This document is the Accepted Manuscript version. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.In this paper, we consider the problem of cooperative communication between relays and base station in an advanced MIMO-OFDM framework, under the assumption that the relays are supplied by electric power drawn from energy harvesting (EH) sources. In particular, we focus on the relay selection, with the goal to guarantee the required performance in terms of capacity. In order to maximize the data throughput under the EH constraint, we model the transmission scheme as a non-transferable coalition formation game, with characteristic function based on an approximated capacity expression. Then, we introduce a powerful mathematical tool inherent to coalitional game theory, namely: the Shapley value (Sv) to provide a reliable solution concept to the game. The selected relays will form a virtual dynamically-configuredMIMO network that is able to transmit data to destination using efficient space-time coding techniques. Numerical results, obtained by simulating the EH-powered cooperativeMIMO-OFDMtransmission with Algebraic Space-Time Coding (ASTC), prove that the proposed coalitional game-based relay selection allows to achieve performance very close to that obtained by the same system operated by guaranteed power supply. The proposed methodology is finally compared with some recent related state-of-the-art techniques showing clear advantages in terms of link performance and goodput.Peer reviewe
A Linear Multi-User Detector for STBC MC-CDMA Systems based on the Adaptive Implementation of the Minimum-Conditional Bit-Error-Rate Criterion and on Genetic Algorithm-assisted MMSE Channel Estimation
The implementation of efficient baseband receivers characterized by affordable computational load is a crucial point in the development of transmission systems exploiting diversity in different domains. In this paper, we are proposing a linear multi-user detector for MIMO MC-CDMA systems with Alamouti’s Space-Time Block Coding, inspired by the concept of Minimum Conditional Bit-Error-Rate (MCBER) and relying on Genetic-Algorithm (GA)-assisted MMSE channel estimation. The MCBER combiner has been implemented in adaptive way by using Least-Mean-Square (LMS) optimization. Firstly, we shall analyze the proposed adaptive MCBER MUD receiver with ideal knowledge of Channel Status Information (CSI). Afterwards, we shall consider the complete receiver structure, encompassing also the non-ideal GA-assisted channel estimation. Simulation results evidenced that the proposed MCBER receiver always outperforms state-of-the-art receiver schemes based on EGC and MMSE criterion exploiting the same degree of channel knowledge (i.e. ideal or estimated CSI)
An emergency communication system based on software-defined radio
Wireless telecommunications represent an important asset for Public Protection and Disaster Relief (PPDR) organizations as they improve the coordination and the distribution of information among first responders in the field. In large international disaster scenarios, many different PPDR organizations may participate to the response phase of disaster management. In this context, PPDR organizations may use different wireless communication technologies; such diversity may create interoperability barriers and degrade the coordination among first time responders. In this paper, we present the design, system integration and testing of a demonstration system based on Software Defined Radio (SDR) technology and Software Communication Architecture (SCA) to support PPDR operations with special focus on the provision of satellite communications. This
paper describes the main components of the demonstration system, the integration activities as well as the testing scenarios, which were used to evaluate the technical feasibility. The paper also describes the main technical challenges in the implementation and integration of the demonstration system. Finally future developments for this technology and potential deployment challenges are presented.JRC.G.6-Digital Citizen Securit
A Near-Optimum Multiuser Receiver for STBC MC-CDMA Systems Based on Minimum Conditional BER Criterion and Genetic Algorithm-Assisted Channel Estimation
The implementation of efficient baseband receivers characterized by affordable computational load is a crucial point in the development of transmission systems exploiting diversity in different domains. This would be a crucial point in the future development of 4G systems, where space, time, and frequency diversity will be combined together in order to increase system throughput. In this framework, a linear multiuser detector for MC-CDMA systems with Alamouti's Space-Time Block Coding (STBC), which is inspired by the concept of Minimum Conditional Bit Error Rate (MCBER), is proposed. The MCBER combiner has been implemented in adaptive way by using Least-Mean-Square (LMS) optimization. The estimation of Channel State Information (CSI), necessary to make practically feasible the MCBER detection, is aided by a Genetic Algorithm (GA). The obtained receiver scheme is near-optimal, as both LMS-based MCBER and GA-assisted channel estimation perform closely to optimum in fulfilling their respective tasks. Simulation results evidenced that the proposed receiver always outperforms state-of-the-art receiver schemes based on EGC and MMSE criterion exploiting the same degree of channel knowledge
Cyclic Adenosine 5′-Monophosphate and Calcium Induce CD152 (CTLA-4) Up-Regulation in Resting CD4+ T Lymphocytes
Abstract
The CTLA-4 (CD152) molecule is up-regulated upon T cell activation and proliferation, and plays a critical role in the inhibition of immune responses. We show in this study that cAMP induces up-regulation of CD152 in human CD4+ T lymphocytes. This effect occurs in the absence of the up-regulation of CD69 and CD25 activation markers and T cell proliferation. In addition, we found that the Ca2+ ionophore ionomycin also up-regulates CD152, and that the combination of a cAMP analog or cAMP inducers with ionomycin further enhances the expression of CD152 in resting CD4+ T lymphocytes. However, cyclosporin A, which inhibits Ca2+/calcineurin signaling pathway, fully prevented the ionomycin- but not the cAMP-induced up-regulation of CD152. The effects of cAMP and ionomycin involve increase of both CD152 mRNA transcripts, coding for the membrane and the soluble forms of CD152. Furthermore, we show that CD152 molecules are translocated to the membrane and are functional, as their engagement by specific mAbs prevented NF-κB activation by anti-CD3/CD28 stimulation. These findings demonstrate that at least two novel signal pathways regulate CTLA-4 gene expression and CD152 molecule up-regulation in human CD4+ T lymphocytes, in the absence of full T cell activation
Use of cerebrospinal fluid and serum samples impregnated on FTA (TM) Elute filter paper for the diagnosis of infections caused by Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae
BACKGROUND:The lack of information regarding the burden of acute bacterial meningitis in Latin America leads to a reduction in the estimated incidence rates of the disease, and impairs public health decisions on the use and follow-up of preventive interventions, particularly, the evaluation of existing vaccination policies. The use of the real-time PCR in diagnostic routine procedures has resulted in a substantial increase in confirmed bacterial meningitis cases. However, in resource-poor countries, these assays are only available in reference laboratories. Sample transportation to these laboratories is a critical constraint, as it requires specialized, high cost courier services. To overcome this barrier we evaluated the use of FTATM Elute filter paper cards for the conservation and processing of samples under normal environmental conditions, as they would be when transported from remote and under-equipped healthcare facilities to the reference centers. A total of 401 samples received in 2015 as part of Sao Paulo's national surveillance for routine diagnosis were selected for this study. METHODS:The sensitivity and specificity of real-time PCR were evaluated using fresh serum and cerebrospinal fluid (CSF) samples processed using our laboratory's standard DNA extraction, and processing the same samples after being dried and stored on FTATM card, and DNA extracted following the manufacturer's instructions. RESULTS:The sensitivities for detection of Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae from CSF dried and stored on FTATM cards were 98%, 92%, and 100%, respectively, and with serum samples were 73%, 88%, and 100%, respectively. When compared to our laboratory's standard methodology, results showed high concordance, with Kappa index ranges of 0.9877-1.00 for CSF, and 0.8004-1.00 for serum samples. CONCLUSION:The use of FTATM cards for CSF and serum conservation and transport represents a rapid, reliable, and cost-effective alternative that will allow obtaining valuable epidemiological information that would otherwise be lost
Relação genética entre cepas de Neisseria meningitidis sorogrupo B sorotipo 4
We compared the results obtained by serotyping of PorB epitopes using an expanded panel of monoclonal antibodies (mAb) including mAb 7 and mAb 10, with results obtained by RFLP of rRNA genes (ribotyping). The purpose of this study was to assess the correlation between phenotypic- and genotypic- methods for typing N. meningitidis. The ribotypes obtained using ClaI or EcoRV endonucleases grouped the strains in seven and two different patterns, respectively. This additional characterization of PorB epitopes improved the correlation between these two methods of typing N. meningitidis.Nós comparamos os resultados obtidos pela sorotipagem usando um painel de anticorpos monoclonais (mAb) ao qual se incluÃam os mAbs 7 e 10, com os resultados obtidos pelo RFLP do gene rRNA (ribotipagem). O propósito deste estudo foi avaliar a correlação entre os métodos fenotÃpico e genotÃpico de tipagem de N. meningitidis. Os ribotipos obtidos usando as endonucleases de restrição ClaI e EcoRV foram hábeis em dividir as cepas em sete e dois diferentes perfis de restrição, respectivamente. A caracterização adicional de epÃtopos na proteÃna PorB melhorou a correlação entre os dois métodos de tipagem de N. meningitidis
Sequencing of 16S rRNA Gene: A Rapid Tool for Identification of Bacillus anthracis
In a bioterrorism event, a tool is needed to rapidly differentiate Bacillus anthracis from other closely related spore-forming Bacillus species. During the recent outbreak of bioterrorism-associated anthrax, we sequenced the 16S rRNA generom these species to evaluate the potential of 16S rRNA gene sequencing as a diagnostic tool. We found eight distinct 16S types among all 107 16S rRNA gene seqs fuences that differed from each other at 1 to 8 positions (0.06% to 0.5%). All 86 B. anthracis had an identical 16S gene sequence, designated type 6; 16S type 10 was seen in all B. thuringiensis strains; six other 16S types were found among the 10 B. cereus strains. This report describes the first demonstration of an exclusive association of a distinct 16S sequence with B. anthracis. Consequently, we were able to rapidly identify suspected isolates and to detect the B. anthracis 16S rRNA gene directly from culture-negative clinical specimens from seven patients with laboratory-confirmed anthrax
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