Comprender el malestar a través de las relaciones. La teoría sistémica: entre epistemología, dinámicas familiares y clínica

El presente trabajo tiene como objetivo el delinear la evolución de las referencias epistemológicas que subyacen al cambio de los modelos de tipo sistémico-relacional. Tal evolución representa el hilo conductor gracias al cual leer las variaciones de perspectiva que ha experimentado la clínica familiar al observar, significar y tratar el malestar en el ámbito de la teoría y de la escena terapéutica. Son dos los saltos epistemológicos que se revelan como fundamentales. El primero es el paso de un modelo homeostático a un modelo evolutivo, paso que ha conducido a los terapeutas a considerar, además de las tensiones hacia el mantenimiento del equilibrio que caracterizan a los sistemas familiares (sobre todo cuando éstos atraviesan un estado de malestar), también los procesos de desarrollo que se hallan en la base del funcionamiento y de las transformaciones de tales sistemas. El segundo es el paso de la cibernética de primer orden a la de segundo orden, paso que ha permitido concebir la relación terapéutica como un proceso de circularidad constructiva entre el observador y el sistema observado y que ha estimulado una apertura hacia nuevas modalidades de tratamiento terapéutico familiar

The organisation of sexuality and the sexuality of organisation: A genealogical analysis of sexual ‘inclusive exclusion’ at work

This article problematises sexual inclusion in the workplace by theorising the social and historical processes that underpin heteronormativity in organisations. Drawing on a genealogical analysis of sexuality and inclusion in four Italian social firms that support the work and social integration of disadvantaged individuals, the article provides an in-depth analysis of the historical conditions affecting the management of sexualities in organisations. The analysis exposes the fragility and contradictory character of the notion of inclusion by illustrating how efforts to ‘include’ are often grounded on normative principles. It also shows how heteronormativity works, in practice, to moderate different modalities of lesbian, gay, bisexual, transgender and queer inclusion, recreating hierarchies and binaries within lesbian, gay, bisexual, transgender and queer individuals. The article discusses how the power of heteronormativity produces specific meanings of inclusion within which some lesbian, gay, bisexual, transgender and queer workers are included and normalised, and others remain excluded because they do not conform to normative conventions and flaunt their ‘diversity’. The necessity of taking a queer perspective on ‘inclusion’ that scrutinises the heteronormative logic is also discussed. The article concludes by shedding light on how, within a heteronormative regime shaped by neoliberal predicaments, ‘inclusive’ organisations might continue to exclude lesbian, gay, bisexual, transgender and queer individuals

The Role of Family Support and Dyadic Adjustment on the Psychological Well-being of Transgender Individuals: An Exploratory Study

Introduction This study aimed to measure dyadic adjustment, social support, and psychological well-being. Methods A research protocol composed of the Dyadic Adjustment Scale, the Outcome Questionnaire 45.2, and the Multidimensional Scale of Perceived Social Support was administered to a sample of 109 Italian transgender individuals. Results Higher levels of global psychological distress, symptom severity, and interpersonal relationship distress were associated with lower levels of family support and dyadic adjustment. In addition, transgender women and younger transgender individuals reported higher levels of interpersonal relationship distress. Conclusions The results indicate that the support and acceptance of one’s partner and family of origin play a crucial role in promoting well-being. It represents an important protective factor with respect to negative psychological health outcomes. Policy Implications The findings emphasize the need to develop specific clinical and social practices for transgender individuals and their families. Building family and partner-centered policies and programs is particularly important to enable transgender individuals to avoid paying the emotional and psychological costs associated with rejection and non-acceptance

Number of Nodes Removed With Inguinofemoral Lymphadenectomy and Risk of Isolated Groin Recurrence in Women With FIGO Stage IB-II Squamous Cell Vulvar Cancer

Aim: The aim of this study was to evaluate if the lymph node count from inguinofemoral lymphadenectomy impacted the risk of isolated groin recurrence in patients with nodenegative squamous cell vulvar cancer.Materials and Methods: This is a retrospective cohort study of women with squamous cell vulvar cancer (stage IBYII according to the 2009 Revised International Federation of Gynecology and Obstetrics staging system) who underwent primary radical vulvar surgery and groin lymphadenectomy between January 2005 and December 2014. Patients' sociodemographic characteristics, the disease characteristics, the number of nodes removed from each groin, and the oncologic outcomewere evaluated. A cutoff value of at least 6 nodes removed from each groin was used to define the adequacy of inguinofemoral dissection.Results: Seventy-six patients, fulfilling the study inclusion criteria, were considered. The mean number of nodes removed (bilaterally) was 14.5 (T5.3, SD), with a range of 2 to 29 nodes. Thirty-three women (43.4%) had less than 6 nodes removed from each groin. In the whole study cohort, 4 cases of isolated groin recurrence (5.3%) were detected, and all these recurrences developed in patients with less than 6 nodes removed. Considering the demographic, clinical, and histopathological characteristics potentially related to the risk of groin recurrence, only the number of nodes removed showed a significant correlation.Conclusions: Women treated for vulvar cancer in which less than 6 nodes are removed from each groin are at higher risk of groin recurrence

Fecal Proteome Profile in Dogs Suffering from Different Hepatobiliary Disorders and Comparison with Controls

In the present study, the fecal proteomes of clinically healthy dogs (HD = n. 10), of dogs showing clinical, ultrasonographic, and/or laboratory evidence of different hepatobiliary dysfunction (DHD = n. 10), and of dogs suffering from chronic hepatitis (CHD = n. 10) were investigated with an Ultimate 3000 nanoUPLC system, coupled to an Orbitrap Fusion Lumos Tribrid mass spectrometer. Fifty-two different proteins of canine origin were identified qualitatively in the three study groups, and quantitative differences were found in 55 proteins when comparing groups. Quantitatively, a total of 41 and 36 proteins were found differentially abundant in the DHD and CHD groups compared to the control HD, and 38 proteins resulted dysregulated in the CHD group as compared to the DHD group. Among the various proteins, differently abundant fecal fibronectin and haptoglobin were more present in the feces of healthy and DHD dogs than in chronic ones, leading us to hypothesize its possible diagnostic/monitoring role in canine chronic hepatitis. On the other hand, the trefoil factor 2 was increased in DHD dogs. Our results show that the analysis of the fecal proteome is a very promising field of study, and in the case of dogs suffering from different hepatobiliary disorders, it was able to highlight both qualitative and quantitative differences among the three groups included

Fecal proteome profile in dogs suffering from different hepatobiliary disorders and comparison with controls

In the present study, the fecal proteomes of clinically healthy dogs (HD = n. 10), of dogs showing clinical, ultrasonographic, and/or laboratory evidence of different hepatobiliary dysfunction (DHD = n. 10), and of dogs suffering from chronic hepatitis (CHD = n. 10) were investigated with an Ultimate 3000 nanoUPLC system, coupled to an Orbitrap Fusion Lumos Tribrid mass spectrometer. Fifty-two different proteins of canine origin were identified qualitatively in the three study groups, and quantitative differences were found in 55 proteins when comparing groups. Quantitatively, a total of 41 and 36 proteins were found differentially abundant in the DHD and CHD groups compared to the control HD, and 38 proteins resulted dysregulated in the CHD group as compared to the DHD group. Among the various proteins, differently abundant fecal fibronectin and haptoglobin were more present in the feces of healthy and DHD dogs than in chronic ones, leading us to hypothesize its possible diagnostic/monitoring role in canine chronic hepatitis. On the other hand, the trefoil factor 2 was increased in DHD dogs. Our results show that the analysis of the fecal proteome is a very promising field of study, and in the case of dogs suffering from different hepatobiliary disorders, it was able to highlight both qualitative and quantitative differences among the three groups included. Results need to be confirmed with western blotting and in further studies