Topical steroid induced Cushing’s syndrome-a rare entity

The topical steroid therapy is the commonest mode of treatment for Psoriasis. When the therapy is overused, it can cause unusual side effects like Cushing’s syndrome which is very rarely reported and we are reporting such a case. Treatment with maintenance dose of steroids is necessary based on basal cortisol levels to avert hypocortisolemic crisis in Cushing’s syndrome, however in some select asymptomatic cases maintenance dose of steroids can be withdrawn and only stress dose be given in spite of low basal serum cortisol. We managed such a case and it is reported because of its rarity in clinical practice. This can alert the clinicians to avoid prescribing steroids as maintenance dose for a long time in asymptomatic Cushing’s syndrome with low morning cortisol and thereby reducing the side effects of long-term steroids on them

Forensic approach to a case of death due to burn injury: a case report

Injuries due to burns are known to have a very high mortality. Burn injuries occur due to a variety of thermal, electrical, mechanical products and can be accidental, suicidal or even homicidal in nature. As the inquiry and research are limited to identifying patterns and causes for burns, the accurate originator and mechanisms are not clearly known. Herein, we report a case of 25 year old female died due to ante-mortem burn injuries with soot particles found in trachea

Effect of ZnO Nanocomposite by Direct and In Direct Sonication Method

The zinc oxide well known for its dielectric property and the anticorrosion, widely used in solar cells. This section deals about the development of the both mechanical and electrical property of Kevlar by adding the ZnO nano composites inside vinyl ester resin. The zinc oxide mixed well with the polyvinyl ester resin without disturbing the chemical behavior of the ZnO. The synthesis of zinc oxide with polyvinyl ester resin done by the direct and indirect sonication process. The kevlar fiber taken as the specimen for this research. The ZnO � polyvinyl ester resin mixed together using the manual without affecting the hydrophobic behavior of the polyvinyl ester resin, the zinc oxide and polyvinyl ester resin mixed with hardener (HY956) with the standard ratio of 5:1. The size of zinc oxide is 75nm. The results show that the direct sonication process giving better tribological properties when compared to indirect sonication process. From the plot and tables it is understood that the kevlar performs superior with ZnO nanocomposites

Fatal Case of Diazepam and Paraquat Poisoning – A Case Report

Background: A very dangerous activity among youth and young adults is the indiscriminate mixing and sharing of prescription drugs, often in combination with alcohol or other drugs. The effects of these combinations of substances can be fatal.Case Report: A 28 years old adult male with alleged history of diazepam and paraquat poisoning was admitted with complaints of chest discomfort, epigastric pain, vomiting and drowsiness. The patient developed acute respiratory distress syndrome (ARDS), multiple organ dysfunction syndrome (MODS) and expired on the next day. To conclude, diazepam even though considered to be a safer drug, has risk of drug abuse and is fatal when taken in overdose along with other central nervous system depressants. Paraquat is a highly toxic compound widely used as herbicide and ingestion of the drug causes death due to respiratory failure. Conclusion: The present study emphasizes on the proper surveillance of diazepam intake in known psychiatric patients and strict rules must be enforced by the Government on marketing of herbicides and pesticides

Impact of Mckenzie Method Enriched by Muscle Energy Technique and Strain Counter Strain Technique on Pain, Range of Motion, Functional Disability and Quality of Life in Patients with Chronic Non-Specific Low Back Pain

BACKGROUND: Recent focus for the patients with chronic non-specific low back pain has been applying manual therapy techniques to attain immediate effects on pain, range of motion, quality of life, etc. Manual therapy techniques were beneficial for patients with chronic non-specific low back pain (CNLBP) both in reducing the symptoms of pain and in improving the function. Manual therapy trails were under process to attain maximum recovery from chronic non-specific low back pain. PURPOSE: The purpose of the present study was to compare McKenzie exercises enriched with Muscle energy technique and McKenzie exercises enriched with Strain counter strain technique in patients with CNLBP. METHODS: Thirty patients (male and female) with age ranging between 20 and 50 years, with CNLBP were assigned randomly to two equal treatment groups. The first group (n=15) underwent a four weeks program of Muscle Energy technique along with McKenzie technique treatment. The second group (n=15) underwent a four weeks program of Strain Counter Strain technique along with McKenzie technique treatment. Outcome measures include pain intensity; lumbar flexion & extension range of movements, functional disability and quality of life were measured. RESULTS: After intervention the present study revealed that patients in both groups showed statistical significance (p 0.05) difference in lumbar flexion range of motion, function disability and quality of life level between both groups and there is a significant difference (p < 0.05) inpain intensity level and lumbar extension range of motion in patients with CNLBP. CONCLUSION: The current results proved that both Muscle energy technique and Strain counter strain technique along with McKenzie technique are effective in reducing pain, increasing lumbar flexion & extension range of motion, functional disability and quality of life in patients with CNLBP

An Efficient Resource Allocation Strategies in Cloud Computing

ABSTRACT: Recently cloud computing booming area and emerging trends in information communication technology domain. Resource allocation is to allocate the resource based on infrastructure as a service (IaaS) is one of the keys for large-scale Cloud applications. Therefore, performance evaluation of workload models and Cloud resource allocation and algorithms in a repeatable manner under different configurations and requirements is difficult. There is still lack of tools that enable developers to compare different resource allocation strategies in IaaS regarding both computing servers and user workloads. To fill this gap in tools for evaluation and modeling of Cloud environments and applications, we propose Cloud computing environment can help developers identify and explore appropriate solutions considering different resource allocation stratigies. we proposed for resource allocation strategies in cloud computing environment such as Cloud data centers, and results by applying the proposed system are analyzed and discussed

An Experimental Study on Solar Flat Plate Collector Using an Alternative Working Fluid

This paper describes the performance of a solar water heater with an alternative working fluid. A solar flat plate collector of fIxed orientation was fabricated and connected to a heat exchanger, which was kept inside the water storage drum. The developed collector was a low temperature device operating with the temperature range of ambient to 100°C. Acetone was selected as an alternative working fluid and allowed to re-eirculate in a closed loop. A shell and tube type heat exchanger (non-mixing) was designed and fabricated for the heat transfer between acetone and water. The solar intensity increased from 55 mw/cm2 at 8.30 am to 85 mw/cm2 at 1.30 pm and decreased to 64 mw/cm2 at 5.00 pm. The absorber plate temperature, which remained nearly constant for the first two hours, went up to 90°C in the next two hours. It was nearly constant from 11.00 am to 1.30 pm and then dropped down to 72°C in the afternoon. The hot fluid was found to loose heat to the surrounding water at more or less constant rate from 11.30 am to 5.00 pm. The highest temperature of acetone (70°C) was observed during 1.00 pm to 2.00 pm. The temperature of water increased from 30°C to a maximum of 62°C. Overall efficiency of the system was found to be 45% while considering the solar input to the heat gained by the water. Alternative working fluids such as acetone, methanol or ethanol may be considered for substituting water in the flat plate collector in view of the fact that the fluids have low boiling point coupled with high latent heat of evaporation

Effect of Thin-Film Adhesives on Mode I Interlaminar Fracture Toughness in Carbon Fiber Composites with Shape Memory Alloy Inserts

A single sheet of NiTi shape memory alloy (SMA) was introduced within a unidirectional HexPly 8552/IM7 (Hexcel) polymer matrix composite (PMC) panel in conjunction with multiple thin-film adhesives to promote the interfacial bond strength between the SMA and PMC. A double cantilever beam (DCB) test was performed in accordance with the ASTM D5528 method for evaluation of Mode I interlaminar fracture toughness of unidirectional fiber-reinforced PMCs. The modal acoustic emissions (MAEs) were monitored during testing with two acoustic sensors attached to the specimens. The composite panels were subjected to a C-scan before testing and examined using optical and scanning electron microscopy (SEM) techniques after part failure. The data were used in conjunction with modified beam theory (MBT), the compliance calibration (CC) method, and the modified compliance calibration (MCC) method. The Mode I interlaminar toughness (G(sub IC)) values for control specimens were higher than previously reported and are attributed to extensive fiber bridging during testing. The presence of adhesives with SMA inserts stabilized crack propagation during DCB testing. The results reveal a new phenomenon of SMA bridging, whereby crack propagation would switch from one side of the SMA insert to the other, thus increasing the load and G(sub IC) values of specimens containing SMA

Mathematical Modeling of the Gas Dynamic Parameters of Impinging Heat-Transfer Medium Jet in Borehole Thermal Reaming Process

Introduction. As compared with other ways of thermal destruction of rocks, the rock destruction by low temperature plasma jet has advantage in terms of distribution of cracks in rock at a considerable depth, high heat transfer coefficient and high specific heat flux, simplified system of automation and remote control, and compactness of thermal tool. Problem Statement. Thus, the possibilities of analytical determination of optimal parameters of thermal effect on rocks are limited by solution of thermoelasticity equations and contact problems of strength theory. Such formulation of the problem is unacceptable due to complication of taking into account substantial changes in the physical and thermos-physical rock properties while heating and applying mechanical load. Due to abovementioned facts it is obviously necessary to develop a mathematical model that enables to define basic gas dynamic jet parameters of heat-transfer medium in the process of borehole thermal reaming. Purpose. The purpose of this research is to develop a mathematical model for calculating the gas dynamic characteristics (pressure, density, and velocity) of the heat-transfer medium while it is moving along the surface of the borehole in the thermal reaming process. Materials and Methods. Mathematical modeling of the flow process for free and impact jets of heat-transfer medium using a PC. Results. Experimental studies have confirmed adequacy of the developed mathematical model for calculation of gas dynamic characteristics (pressure, density, and velocity) of the heat-transfer while it is moving along the surface of the borehole in the process of its thermal reaming. Conclusions. The obtained results can be used for modeling the gas dynamic characteristics in the case of applying a thermal tool with electric discharge in other technologies of heat treatment and destruction of materials.Вступ. Порівняно з іншими способами термічного руйнування гірських порід, руйнування породи за допомогою струмини низькотемпературної плазми відрізняється поширенням тріщин в породі на значну глибину, високими значеннями коефіцієнта тепловіддачі та питомого теплового потоку, спрощеною системою автоматизації та дистанційного управління, компактністю застосовуваного термоінструменту. Проблематика. Можливості аналітичного визначення оптимальних параметрів термічного впливу на гірські породи обмежені розв'язанням рівнянь термопружності та контактних задач теорії міцності. Така постановка задачі є неприйнятною через складність врахування суттєвої зміни фізичних та теплофізичних властивостей гірських порід в процесі їх нагрівання та механічного навантаження. Зважаючи на це, очевидною є необхідність розробки математичної моделі, яка дозволяє визначити основні газодинамічні характеристики струмини теплоносія в процесі термічного розширення свердловини. Мета. Розробка математичної моделі розрахунку газодинамічних характеристик (тиск, густина, швидкість руху) теплоносія при його русі вздовж поверхні свердловини в процесі її термічного розширення. Матеріали й методи. Математичне моделювання процесу течії вільної та імпактної струмини теплоносія з використанням ПЕОМ. Результати. Експериментальними дослідженнями підтверджено адекватність розробленої математичної моделі розрахунку газодинамічних характеристик (тиск, густина, швидкість руху) теплоносія при його русі вздовж поверхні свердловини в процесі її термічного розширення. Висновки. Отримані результати можуть бути використані для моделювання газодинамічних характеристик при застосуванні термоінструмента з дуговим електричним розрядом в інших технологіях термічної обробки та руйнування матеріалів.Введение. По сравнению с другими способами термического разрушения горных пород, разрушение породы с помощью струи низкотемпературной плазмы отличается распространением трещин в породе на значительную глубину, высокими значениями коэффициента теплоотдачи и удельного теплового потока, упрощенной системой ав томатизации и дистанционного управления, компактностью термоинструмента. Проблематика. Возможности аналитического определения оптимальных параметров термического влияния на горные породы ограничиваются решением уравнений термоупругости и контактных задач теории прочности. Такая постановка задачи является неприемлемой вследствие сложности учета существенного изменения физических и теплофизических свойств горных пород в процессе их нагревания и механического нагружения. В связи с этим очевидна необходимость разработки математической модели, которая позволяет определить основные газодинамические характеристики струи теплоносителя в процессе термического расширения скважины. Цель. Разработка математической модели расчета газодинамических характеристик (давление, плотность, скорость движения) теплоносителя при его течении вдоль поверхности скважины в процессе ее термического рас ширения. Материалы и методы. Математическое моделирование процесса течения свободной и импактной струи теплоносителя с использованием ПЭВМ. Результаты. Экспериментальными исследованиями подтверждена адекватность разработанной математической модели расчета газодинамических характеристик (давление, плотность, скорость движения) теплоносителя при его движении вдоль поверхности скважины в процессе ее термического расширения. Выводы. Полученные результаты могут быть использованы для моделирования газодинамических характеристик при применении термоинструмента с дуговым электрическим разрядом в других технологиях термической об работки и разрушения материалов