Athlete's self perceptionsof optimal states in karate : an application of the IZOF model

El estudio examinó las percepciones sobre los estados óptimos de 63 karatekas espanoles de alto nivel. Se utilizaron preguntas abiertas para examinar las experiencias situacionales (estados), los patrones emocionales relativamente stables y las meta-experiencias de los karatekas. Como se esperaba, los estados óptimos estuvieron caracterizados por estados positivos (confianza, tranquilidad), además de negativos (ansiedad, ira). Las descripciones de los karatekas reflejaron los siete componentes de un estado psicobiosocial siendo el afectivo y el cognitivo los componentes más salientes de sus estados óptimos. Los karatekas percibieron sus estados óptimos como transitorios y dinámicos, y utilizaron distintas estrategias para producir y mantener estos estados. Los resultados sugieren que las intervenciones individualizadas no sólo deben limitarse a la reducción de la ansiedad. Se sugieren futuras líneas de investigación e implicaciones prácticas.This study examined self-perceptions of optimal states in 63 high-level Spanish karate athletes. Open-ended questions were used to examine athletes' situational experiences (states), relatively stable emotional patterns and metaexperiences. As expected, optimal states were characterized by pleasant (confidence, calmness) and unpleasant (anxiety, anger) emotions. Athletes' self-descriptions reflected all seven form-components of a psycho-biosocial state with affective and cognitive modalities being the most salient components of their optimal states. Athletes perceived their optimal states as temporary and dynamic and actively used different strategies to produce and maintain these states. The results suggest that individualized interventions should not be limited to the reduction of anxiety. Directions for future research and practical implications are suggested

Idiosyncratic description of anger states in skilled Spanish karate athletes : an application of the IZOF model

This study examined content and intensity of anger prior to, during, and after best ever and worst ever performances in 43 high-level Spanish karate athletes using individualized anger profiling. Optimal and dysfunctional anger intensities were assessed using a modified version of Borg's Category Ratio (CR-10) scale. Anger profiling was supplemented with positive and negative emotion profiling. As expected, content of anger descriptors was highly idiosyncratic. Moreover, great variability in optimal and dysfunctional anger intensities was found at individual and group levels. In best performances, anger was related to the generation of additional energy, whereas in worst performances, anger resulted from a perceived lack of resources or low readiness to perform. Athletes generated different anger descriptors in performance and in non-sport performance situations (overlap ranged from 0 to .35). The results support the use of an idiographic approach in the study of anger states.El estudio examina el contenido e intensidad de estados de ira antes, durante, y después de los mejores y peores rendimientos en 43 karatekas españoles de alto nivel mediante perfiles de ira individuales. Las intensidades de ira óptima y disfuncional se midieron con la escala modificada de Borg (CR-10). Perfiles de emociones positivas y negativas complementaron los perfiles de ira. Como se creía, el contenido de los descriptores de ira fue altamente idiosincrático. Asimismo, hubo gran variabilidad en las intensidades de ira óptima y disfuncional a nivel individual y de grupo. La ira estaba relacionada con la generación de energía en los mejores rendimientos, pero fue el resultado de una falta percibida de recursos o preparación en los peores rendimientos. Los karatekas utilizaron distintos descriptores de ira en situaciones de rendimiento deportivo y fuera del deporte (solapamiento 0 a .35). Los resultados sustentan el uso de un enfoque idiográfico en el estudio de los estados de ira

Interactive effects of emotions on performance: an exploratory study in elite skeet shooters

Este estudio investiga los efectos interactivos de múltiples emociones en el rendimiento (resultado) de tres tiradores de skeet de elite. La escala de emociones agregadas Emotional State Profile-40 (ESP-40; Hanin, 2010b) evalúa las experiencias emocionales recordadas asociadas con rendimientos exitosos y pobres y con rendimientos actuales. El rendimiento actual consiste en 20 series de 25 tiros. Los resultados confirman la utilidad práctica de la escala ESP-40 en la evaluación de los efectos interactivos de cuatro categorías de emoción en el rendimiento deportivo. Las emociones recordadas fueron instrumentales en la predicción de los resultados actuales. Se discute la utilidad de la regresión logística ordinal en la predicción del rendimiento.This study explored interactive effects of multiple emotions on performance (outcomes) in three male elite skeet shooters. Recalled emotional experiences associated to successful and poor performances and to current (actual) performances were measured using the aggregated Emotional State Profile-40 scale (ESP-40; Hanin, 2010b). Current performance involved 20 series of 25 shots. The results provide support for the practical utility of ESP-40 in the assessment of interactive effects of four emotion categories on performance. Recalled measures were instrumental in the prediction of current performances. The utility of ordinal logistic regression-based estimation is discussed.Este estudo investiga os efeitos interactivos de múltiplas emoções no rendimento (resultado) de três atiradores de skeet de elite. A escala de emoções agregadas Emotional State Profile-40 (ESP-40; Hanin, 2010b) avalia as experiências emocionais recordadas associadas com rendimento de sucesso e fracasso e com rendimentos actuais. O rendimento actual consiste em 20 séries de 25 tiros. Os resultados confirmam a utilidade prática da escala ESP-40 na avaliação dos efeitos interactivos de quatro categorias de emoção no rendimento desportivo. As emoções recordadas foram instrumentais na predição dos resultados actuais. É discutida a utilidade da regressão logística ordinal na predição do rendiment

Reservoirs of Red-Spotted Grouper Nervous Necrosis Virus (RGNNV) in Squid and Shrimp Species of Northern Alboran Sea

The production of the aquaculture industry has increased to be equal to that of the world fisheries in recent years. However, aquaculture production faces threats such as infectious diseases. Betanodaviruses induce a neurological disease that affects fish species worldwide and is caused by nervous necrosis virus (NNV). NNV has a nude capsid protecting a bipartite RNA genome that consists of molecules RNA1 and RNA2. Four NNV strains distributed worldwide are discriminated according to sequence homology of the capsid protein encoded by RNA2. Since its first description over 30 years ago, the virus has expanded and reassortant strains have appeared. Preventive treatments prioritize the RGNNV (red-spotted grouper nervous necrosis virus) strain that has the highest optimum temperature for replication and the broadest range of susceptible species. There is strong concern about the spreading of NNV in the mariculture industry through contaminated diet. To surveil natural reservoirs of NNV in the western Mediterranean Sea, we collected invertebrate species in 2015 in the Alboran Sea. We report the detection of the RGNNV strain in two species of cephalopod mollusks (Alloteuthis media and Abralia veranyi), and in one decapod crustacean (Plesionika heterocarpus). According to RNA2 sequences obtained from invertebrate species and reported to date in the Mediterranean Sea, the strain RGNNV is predominant in this semienclosed sea. Neither an ecosystem- nor host-driven distribution of RGNNV were observed in the Mediterranean basin.Versión del edito

Real‑life analysis on safety and efcacy of asciminib for ponatinib pretreated patients with chronic myeloid leukemia

Asciminib; Inhibitors; LeukemiaAsciminib; Inhibidors; LeucèmiaAsciminib; Inhibidores; LeucemiaFailure of second-generation tyrosine kinase inhibitors (2GTKI) is a challenging situation in patients with chronic myeloid leukemia (CML). Asciminib, recently approved by the US Federal Drug Administration, has demonstrated in clinical trials a good efficacy and safety profile after failure of 2GTKI. However, no study has specifically addressed response rates to asciminib in ponatinib pretreated patients (PPT). Here, we present data on responses to asciminib from 52 patients in clinical practice, 20 of them (38%) with prior ponatinib exposure. We analyzed retrospectively responses and toxicities under asciminib and compared results between PPT and non-PPT patients.After a median follow-up of 30 months, 34 patients (65%) switched to asciminib due to intolerance and 18 (35%) due to resistance to prior TKIs. Forty-six patients (88%) had received at least 3 prior TKIs. Regarding responses, complete cytogenetic response was achieved or maintained in 74% and 53% for non-PPT and PPT patients, respectively. Deeper responses such as major molecular response and molecular response 4.5 were achieved in 65% and 19% in non-PPT versus 32% and 11% in PPT, respectively. Two patients (4%) harbored the T315I mutation, both PPT.In terms of toxicities, non-PPT displayed 22% grade 3-4 TEAE versus 20% in PPT. Four patients (20% of PPT) suffered from cross-intolerance with asciminib as they did under ponatinib.Our data supports asciminib as a promising alternative in resistant and intolerant non-PPT patients, as well as in intolerant PPT patients; the resistant PPT subset remains as a challenging group in need of further therapeutic options

Detection of Red-spotted grouper nervous necrosis virus (RGNNV) in shrimp and squid of the Mediterranean Sea

The quest for sustainable fisheries and procurement of food supply has increased aquaculture production up to the world fisheries capture. Viral encephalopathy and retinopathy (VER), also known as viral nervous necrosis (VNN), is caused by nervous necrosis virus (NNV) and results in high mortality of larvae and juveniles of continuous increasing amount of fish species. The disease causes vacuolation and necrosis of the central nervous system. The virus has a nude capsid protecting a bipartite RNA genome that consists of positive stranded molecules RNA1 and RNA2. Four NNV genotype strains distributed worldwide are discriminated according to sequence homology of the capsid protein encoded by RNA2. Preventive treatments prioritize the RGNNV (Redspotted grouper nervous necrosis virus) genotype that has the highest optimum temperature for replication and the broadest range of susceptible species. A flow of NNV between wild and cultured fish had been demonstrated, and reservoirs of NNV have been reported in invertebrates, raising concern on the spreading of NNV in the mariculture industry through contaminated food. The present study aimed to contribute in the surveillance of reservoirs of NNV in invertebrates of the unexplored western Mediterranean Sea. We report the detection of the RGNNV strain in two species of squid (Alloteuthis media and Abralia veranyi), and in one shrimp (Plesionika heterocarpus) collected in 2015 in the Alboran Sea. According to RNA2 sequences obtained from invertebrates and reported to date in the Mediterranean Sea, the strain RGNNV is predominant in this semi-enclosed sea. Our results suggest that RGNNV distribution is apparently independent of host species and ecosystem, and similar between invertebrates and fish species that feed on invertebrates, calling for an increase in surveillance of NNV reservoirs in the wild.European Association of Fish Pathologists. PathoVe

Detection of Red-spotted grouper nervous necrosis virus (RGNNV) in shrimp and squid of the Mediterranean Sea

The quest for sustainable fisheries and procurement of food supply has increased aquaculture production up to the world fisheries capture. Viral encephalopathy and retinopathy (VER), also known as viral nervous necrosis (VNN), is caused by nervous necrosis virus (NNV) and results in high mortality of larvae and juveniles of continuous increasing amount of fish species. The disease causes vacuolation and necrosis of the central nervous system. The virus has a nude capsid protecting a bipartite RNA genome that consists of positive stranded molecules RNA1 and RNA2. Four NNV genotype strains distributed worldwide are discriminated according to sequence homology of the capsid protein encoded by RNA2. Preventive treatments prioritize the RGNNV (Redspotted grouper nervous necrosis virus) genotype that has the highest optimum temperature for replication and the broadest range of susceptible species. A flow of NNV between wild and cultured fish had been demonstrated, and reservoirs of NNV have been reported in invertebrates, raising concern on the spreading of NNV in the mariculture industry through contaminated food. The present study aimed to contribute in the surveillance of reservoirs of NNV in invertebrates of the unexplored western Mediterranean Sea. We report the detection of the RGNNV strain in two species of squid (Alloteuthis media and Abralia veranyi), and in one shrimp (Plesionika heterocarpus) collected in 2015 in the Alboran Sea. According to RNA2 sequences obtained from invertebrates and reported to date in the Mediterranean Sea, the strain RGNNV is predominant in this semi-enclosed sea. Our results suggest that RGNNV distribution is apparently independent of host species and ecosystem, and similar between invertebrates and fish species that feed on invertebrates, calling for an increase in surveillance of NNV reservoirs in the wild.European Association of Fish Pathologists. PathoVe

Athletes’ basic psychological needs and emotions: the role of cognitive reappraisal

In sport, where high achievements are at stake, athletes often feel pressure and emotions that hinder their performance. Emotion regulation becomes essential for athletes to handle stress, achieve optimal performance, and enhance their overall well-being. To advance both research and practical applications, it is crucial to examine the antecedents of emotion regulation and the impact on emotions and other feelings associated with performance. Specifically, the purpose of this cross-sectional study was to examine the role of athletes’ emotion regulation strategies (i.e., cognitive reappraisal and expressive suppression) in the relationship between basic psychological needs satisfaction, emotions, and psychobiosocial experiences. The sample consisted of 424 competitive athletes (246 men and 178 women) involved in individual sports (n = 164; e.g., fencing, gymnastics, martial arts, swimming, and tennis) or team sports (n = 260; e.g., basketball, rugby, soccer, and volleyball), aged 16–36  years (M = 23.08, SD = 7.65). Their competitive experience ranged from 1 to 21  years (M = 9.71, SD = 6.34) at regional (71%), national (18%), or international (11%) level, and they practiced their sport on average 3.74 times a week (SD = 1.73). Participants completed measures of basic needs satisfaction (i.e., competence, autonomy, and relatedness), emotion regulation style, emotions, and psychobiosocial experiences. Structural equation modeling results showed that competence need satisfaction was positively associated with pleasant emotions and psychobiosocial experiences that are perceived as functional for performance, and negatively associated with a maladaptive emotion regulation style (i.e., expressive suppression) and unpleasant emotions. Relatedness need satisfaction was positively related to an adaptive emotion regulation style (i.e., cognitive reappraisal), pleasant emotions, and psychobiosocial experiences, and negatively related to expressive suppression and unpleasant emotions. Finally, mediation analysis showed positive indirect effects from autonomy and relatedness satisfaction to pleasant emotions and psychobiosocial experiences via cognitive reappraisal. Findings suggest that the satisfaction of athletes’ basic psychological needs of autonomy and relatedness is related to the experience of pleasant emotions and functional psychobiosocial states when they adopt an adaptive emotion regulation style

Phase Transformation Dynamics in Sulfate-Loaded Lanthanide Triphosphonates. Proton Conductivity and Application as Fillers in PEMFCs

Phase transformation dynamics and proton conduction properties are reported for cationic layer-featured coordination polymers derived from the combination of lanthanide ions (Ln3+) with nitrilo-tris(methylenephosphonic acid) (H6NMP) in the presence of sulfate ions. Two families of materials are isolated and structurally characterized, i.e., [Ln2(H4NMP)2(H2O)4](HSO4)2·nH2O (Ln = Pr, Nd, Sm, Eu, Gd, Tb, Er, Yb; n = 4−5, Series I) and [Ln(H5NMP)]SO4· 2H2O (Ln = Pr, Nd, Eu, Gd, Tb; Series II). Eu/Tb bimetallic solid solutions are also prepared for photoluminescence studies. Members of families I and II display high proton conductivity (10−3 and 10−2 S·cm−1 at 80 °C and 95% relative humidity) and are studied as fillers for Nafion-based composite membranes in PEMFCs, under operating conditions. Composite membranes exhibit higher power and current densities than the pristine Nafion membrane working in the range of 70−90 °C and 100% relative humidity and with similar proton conductivity.Proyectos de Ministero de Ciencia e Innovación MAT2016-77648-R (MICINN/FEDER); PID2019-110249RB-I00 (MICINN/FEDER) y la Junta de Andalucía (FQM113). Funding for open access change: Universidad de Málaga/ CBU

Study protocol of effectiveness of a biopsychosocial multidisciplinary intervention in the evolution of non-speficic sub-acute low back pain in the working population : cluster randomised trial

Background: Non-specific low back pain is a common cause for consultation with the general practitioner, generating increased health and social costs. This study will analyse the effectiveness of a multidisciplinary intervention to reduce disability, severity of pain, anxiety and depression, to improve quality of life and to reduce the incidence of chronic low back pain in the working population with non-specific low back pain, compared to usual clinical care. Methods/Design: A Cluster randomised clinical trial will be conducted in 38 Primary Health Care Centres located in Barcelona, Spain and its surrounding areas. The centres are randomly allocated to the multidisciplinary intervention or to usual clinical care. Patients between 18 and 65 years old (n = 932; 466 per arm) and with a diagnostic of a non-specific sub-acute low back pain are included. Patients in the intervention group are receiving the recommendations of clinical practice guidelines, in addition to a biopsychosocial multidisciplinary intervention consisting of group educational sessions lasting a total of 10 hours. The main outcome is change in the score in the Roland Morris disability questionnaire at three months after onset of pain. Other outcomes are severity of pain, quality of life, duration of current non-specific low back pain episode, work sick leave and duration, Fear Avoidance Beliefs and Goldberg Questionnaires. Outcomes will be assessed at baseline, 3, 6 and 12 months. Analysis will be by intention to treat. The intervention effect will be assessed through the standard error of measurement and the effect-size. Responsiveness of each scale will be evaluated by standardised response mean and receiver-operating characteristic method. Recovery according to the patient will be used as an external criterion. A multilevel regression will be performed on repeated measures. The time until the current episode of low back pain takes to subside will be analysed by Cox regression. Discussion: We hope to provide evidence of the effectiveness of the proposed biopsychosocial multidisciplinary intervention in avoiding the chronification of low back pain, and to reduce the duration of non-specific low back pain episodes. If the intervention is effective, it could be applied to Primary Health Care Centres