Technoethics and Human Rights: The Metaethical Implications of Crisismapping and the Right to Privacy in Post-Disaster, Post-Conflict Scenarios

Do invasive digital approaches to disaster response come at too high of a cost to privacy, such that we should seek alternative methods or regulations? This paper examines the tension between the right to privacy and crisismapping, a new technological advancement in emergency response. After mapping the critical international institutions and stakeholders, the paper grounds interests to effective triage and to digital privacy in international human rights law. A thought experiment is offered to show our conflicting intuitions when privacy is weighed against critical safety interests, and multiple procedures are evaluated as means to reconcile these interests and determine the extent of the right to privacy. Ultimately, the paper calls for an expanded inquiry by the United Nations Special Rapporteur on the Right to Privacy, who has the power to engage multiple stakeholders for a fair and inclusive new approach. Privacy costs are too fundamental for emergency response to proceed without proper scrutiny

Safety and Security in Remote, Rural, and Regional Policing

Policing outside of the metropole is unlike what we have come to know about policing. The rural, regional and remote (RRR) policing environment is shaped by environmental, organisational, community and criminality contexts that produce unique safety and security issues. This article examines these issues for RRR police and their families in Tasmania, Australia. Drawing on interviews with eight officers and observations of five officers in two districts, we find that both distance and isolation, and closeness (or propinquity), shapes the safety and security of RRR police. This article documents the individual strategies deployed by RRR officers to ensure their and their family’s safety, the gaps in policy and practice, and the necessary changes to the work conditions, station security, and housing arrangements of RRR officers. Addressing a gap at the juncture of RRR policing and police safety and security, this research considers what can be done to enhance the capacity of RRR officers to remain in RRR deployments

Chlorhexidine-induced elastic and adhesive changes of Escherichia coli cells within a biofilm

Chlorhexidine is a widely used, commercially available cationic antiseptic. Although its mechanism of action on planktonic bacteria has been well explored, far fewer studies have examined its interaction with an established biofilm. The physical effects of chlorhexidine on a biofilm are particularly unknown. Here, the authors report the first observations of chlorhexidine-induced elastic and adhesive changes to single cells within a biofilm. The elastic changes are consistent with the proposed mechanism of action of chlorhexidine. Atomic force microscopy and force spectroscopy techniques were used to determine spring constants and adhesion energy of the individual bacteria within an Escherichia coli biofilm. Medically relevant concentrations of chlorhexidine were tested, and cells exposed to 1% (w/v) and 0.1% more than doubled in stiffness, while those exposed to 0.01% showed no change in elasticity. Adhesion to the biofilm also increased with exposure to 1% chlorhexidine, but not for the lower concentrations tested. Given the prevalence of chlorhexidine in clinical and commercial applications, these results have important ramifications on biofilm removal technique

Improving Employee Productivity Using Effective Leadership Strategies

Low employee productivity has the potential to impact small business outcomes negatively. Small business leaders who can develop and use strategies to increase employee productivity, improve employee morale, and lower employee turnover rates can help a business succeed and grow. Grounded in the decision-making model of leadership theory, the purpose of this qualitative, multiple case study was to identify strategies some small business leaders use to increase employee productivity. The participants consisted of one leader from five different small businesses who had experience implementing leadership strategies to improve employee productivity. Data were collected using semistructured interviews, a review of documents, and reflective journaling. Through Yin’s five-step process, four themes were identified: (a) leadership styles, (b) communication barriers, (c) problem solving, and (d) motivation. A key recommendation is for leaders to get to know their employees personally. The implications for positive social change include helping leaders develop effective leadership strategies that could increase employee productivity to gain a competitive advantage

Two New Techniques for Evaluating Connectivity of Septic Fields to Great Lake Watersheds and Embayments

Pictometry Oblique Imagery was successfully used to map septic fields in Oak Orchard watershed. Analysis of the imagery proved to be efficient for finding leach fields, and between 66 to 81% of the septic fields previously mapped by the Genesee Orleans County Department of Health, were identified. The remainder were not identified because of canopy cover, or were either septic systems without leach fields, the septic field postdated the imagery, or were not visible. Consequently under ideal conditions (septic systems with leach fields and no canopy or shadows) the method should be able to identify over 80% of the systems. Imagery taken during the transition from dormant to growing season proved best for identifying leach fields. One example of a plume from a short circuited system was recorded. A total of 1277 septic fields were mapped in the watershed. Spatial distribution was heterogenous, with dense sites of septic fields concentrated along residential road corridors. Approximately 4.2% of the leach fields were located less than 100 feet of a tributary. This is below the minimum separation distance of a leach field to a waterbody that is required by the NYS Department of Health code. The average distance of a leach field to a tributary is 327 meters with 50% of the leach fields occurring within 240 meters of mapped tributaries. Maps of important septic field “hotspots” were developed for watershed stakeholders and include tributaries along Batavia-Elba Townline Rd., Marsh Creek, and tributaries near the intersections of Alleghany and Lockport Rds, Judge Rd and Knowlesville Rd., and Lockport and Albion Rd. Considerable numbers of septic fields occur along Lake Alice in the main stem of the river, however this stretch is probably diluted by water input from the Erie Canal at the Glendale Dam. In a second set of experiments, a new DNA-based groundwater tracer was introduced to two septic systems to see if it could be used to trace individual septic systems. The tracer was not discovered in one site, however, a breakthrough curve was obtained in the second site 31 days after being introduced into the toilet. This tracer passed through at least 200 meters of groundwater flowpath and 1 km of stream. The results of these experiments suggest that frequent, systematic sampling and careful lab protocols to identify the signal to noise threshold of the procedure are critical to the success of the technique. In summary we suggest that Pictometry Oblique Imagery can be used to map septic fields in a watershed and that the DNA Tracer technique may be successful in some septic systems. Further research needs to be conducted to improve the success of the latter

Could perturbed fetal development of the ovary contribute to the development of polycystic ovary syndrome in later life?

Polycystic ovary syndrome (PCOS) affects around 10% of young women, with adverse consequences on fertility and cardiometabolic outcomes. PCOS appears to result from a genetic predisposition interacting with developmental events during fetal or perinatal life. We hypothesised that PCOS candidate genes might be expressed in the fetal ovary when the stroma develops; mechanistically linking the genetics, fetal origins and adult ovarian phenotype of PCOS. In bovine fetal ovaries (n = 37) of 18 PCOS candidate genes only SUMO1P1 was not expressed. Three patterns of expression were observed: early gestation (FBN3, GATA4, HMGA2, TOX3, DENND1A, LHCGR and FSHB), late gestation (INSR, FSHR, and LHCGR) and throughout gestation (THADA, ERBB4, RAD50, C8H9orf3, YAP1, RAB5B, SUOX and KRR1). A splice variant of FSHB exon 3 was also detected early in the bovine ovaries, but exon 2 was not detected. Three other genes, likely to be related to the PCOS aetiology (AMH, AR and TGFB1I1), were also expressed late in gestation. Significantly within each of the three gene groups, the mRNA levels of many genes were highly correlated with each other, despite, in some instances, being expressed in different cell types. TGFβ is a well-known stimulator of stromal cell replication and collagen synthesis and TGFβ treatment of cultured fetal ovarian stromal cells inhibited the expression of INSR, AR, C8H9orf3 and RAD50 and stimulated the expression of TGFB1I1. In human ovaries (n = 15, < 150 days gestation) many of the same genes as in bovine (FBN3, GATA4, HMGA2, FSHR, DENND1A and LHCGR but not TOX3 or FSHB) were expressed and correlated with each other. With so many relationships between PCOS candidate genes during development of the fetal ovary, including TGFβ and androgen signalling, we suggest that future studies should determine if perturbations of these genes in the fetal ovary can lead to PCOS in later life

The relationships of experiencing workplace bullying with mental health, affective commitment, and job satisfaction: application of the job demands control model

There have been very few theoretical models published to understand the relationship between workplace bullying and different outcome variables. Applying the Job Demands Control (JDC) model, this study analyzed workplace bullying alongside 'traditional' job stressors of role overload and low job control to determine the relative associations of each with mental health and wellbeing. These relative associations have not been well documented. Data were obtained from an organizational climate questionnaire administered to 21 Australian Defence Force units (n = 3193). Results indicated that the correlations between bullying and psychological distress (r = 0.39), job satisfaction (r = -0.28), and affective commitment (r = -0.22) were all significant and for some outcomes greater than those involving the traditional job stressors. Furthermore, for each of these three outcomes, bullying contributed incremental variance after controlling for other job demands. These results support earlier claims that workplace bullying requires the same attention given to traditional work stressors. The JDC model provides a strong theoretical base to investigate workplace bullying. Testing against other stressors allows for consideration of the broader context of workplace bullying when managing the workforce

Regulation of fibrillins and modulators of TGFβ in fetal bovine and human ovaries

Fibrillins 1–3 are stromal extracellular matrix proteins that play important roles in regulating TGFβ activity, which stimulates fibroblasts to proliferate and synthesize collagen. In the developing ovary, the action of stroma is initially necessary for the formation of ovigerous cords and subsequently for the formation of follicles and the surface epithelium of the ovary. FBN3 is highly expressed only in early ovarian development and then it declines. In contrast, FBN1 and 2 are upregulated in later ovarian development. We examined the expression of FBN1–3 in bovine and human fetal ovaries. We used cell dispersion and monolayer culture, cell passaging and tissue culture. Cells were treated with growth factors, hormones or inhibitors to assess the regulation of expression of FBN1–3. When bovine fetal ovarian tissue was cultured, FBN3 expression declined significantly. Treatment with TGFβ-1 increased FBN1 and FBN2 expression in bovine fibroblasts, but did not affect FBN3 expression. Additionally, in cultures of human fetal ovarian fibroblasts (9–17 weeks gestational age), the expression of FBN1 and FBN2 increased with passage, whereas FBN3 dramatically decreased. Treatment with activin A and a TGFβ family signaling inhibitor, SB431542, differentially regulated the expression of a range of modulators of TGFβ signaling and of other growth factors in cultured human fetal ovarian fibroblasts suggesting that TGFβ signaling is differentially involved in the regulation of ovarian fibroblasts. Additionally, since the changes in FBN1–3 expression that occur in vitro are those that occur with increasing gestational age in vivo, we suggest that the fetal ovarian fibroblasts mature in vitro.Nicole A Bastian, Rosemary A Bayne, Katja Hummitzsch, Nicholas Hatzirodos, Wendy M Bonner, Monica D Hartanti, Helen F Irving-Rodgers, Richard A Anderson and Raymond J Rodger

Exploring the Requisite Skills and Competencies of Pharmacists Needed for Success in an Evolving Health Care Environment

Objective. To identify and describe the core competencies and skills considered essential for success of pharmacists in today’s rapidly evolving health care environment