220GHz wideband 3D imaging radar for concealed object detection technology development and phenomenology studies

Part of the research leading to these results has received funding from the European Union Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 312745.We present a 220 GHz 3D imaging ‘Pathfinder’ radar developed within the EU FP7 project CONSORTIS (Concealed Object Stand-Off Real-Time Imaging for Security) which has been built to address two objectives: (i) to de-risk the radar hardware development and (ii) to enable the collection of phenomenology data with ~1 cm3 volumetric resolution. The radar combines a DDS-based chirp generator and self-mixing multiplier technology to achieve a 30 GHz bandwidth chirp with such high linearity that the raw point response is close to ideal and only requires minor nonlinearity compensation. The single transceiver is focused with a 30 cm lens mounted on a gimbal to acquire 3D volumetric images of static test targets & materials.Publisher PD

A 220 GHz 3D imaging radar with sub-cm3 voxel resolution for security applications

Radars operating at high millimetre and sub-millimetre wave frequencies are promising candidates for security applications such as people screening since they offer the possibility to form 3D images through clothing with sufficient resolution to detect concealed objects. High spatial resolution of order 1 cm can be achieved using practically sized antennas and high range resolution can be achieved using wideband FMCW chirps, e.g. 30 GHz, to yield 0.5 cm range bins. We present a 220 GHz test-bed ‘Pathfinder’ radar which achieves sub-cm3 voxel resolution with very high signal fidelity. The radar is used to de-risk technology under development for next generation people screening systems.Postprin

Ueber die Behandlung der Geburt bei Atresie der Vagina

http://www.ester.ee/record=b3581049*es

Localization of speech synthesis systems for Irish voice web operations

As the information age creates growing consumer demand for information, anytime and anyplace voice applications and voice based services are dramatically changing the way people and businesses communicate. Voice portals established an early market but the development of advanced voice applications has introduced speech technology to the masses

Learning to Rank Question Answer Pairs with Holographic Dual LSTM Architecture

We describe a new deep learning architecture for learning to rank question answer pairs. Our approach extends the long short-term memory (LSTM) network with holographic composition to model the relationship between question and answer representations. As opposed to the neural tensor layer that has been adopted recently, the holographic composition provides the benefits of scalable and rich representational learning approach without incurring huge parameter costs. Overall, we present Holographic Dual LSTM (HD-LSTM), a unified architecture for both deep sentence modeling and semantic matching. Essentially, our model is trained end-to-end whereby the parameters of the LSTM are optimized in a way that best explains the correlation between question and answer representations. In addition, our proposed deep learning architecture requires no extensive feature engineering. Via extensive experiments, we show that HD-LSTM outperforms many other neural architectures on two popular benchmark QA datasets. Empirical studies confirm the effectiveness of holographic composition over the neural tensor layer.Comment: SIGIR 2017 Full Pape

Submillimetre wave 3D imaging radar for security applications

There is ongoing worldwide interest in finding solutions to enhance the security of civilians at airports, borders and high risk public areas in ways which are safe, ethical and streamlined. One promising approach is to use submillimetre wave 3D imaging radar to detect concealed threats as it offers the advantages of high volumetric resolution (~1 cm3) with practically sized antennas (<0.5 m) such that even quite small objects can be resolved through clothing. The Millimetre Wave Group at the University of St Andrews has been developing submillimetre wave 3D imaging radars for security applications since 2007. A significant goal is to achieve near real-time frame rates of at least 10 Hz, to cope with dynamic scenes, over wide fields of view at short range with high pixel counts. We review the radar systems we have developed at 340 and 220 GHz and the underpinning technologies which we have employed to realise these goals.PostprintNon peer reviewe

Role of vasopressin in impaired water excretion in conscious rats with experimental cirrhosis

Role of vasopressin in impaired water excretion in conscious rats with experimental cirrhosis. The present study was undertaken to study the mechanism of impaired water excretion in experimental cirrhosis in the rat. Conscious rats in whom histologically proven cirrhosis was induced with carbon tetrachloride and phenobarbital were compared with control rats given phenobarbital alone. Impaired water excretion in experimental cirrhosis was verified by a basal hyponatremia (138 vs. 147 mEq/liter, P < 0.005) and an impaired excretion of water load (minimal urinary osmolality, 262 vs. 100 mOsm/kg; 58 vs. 102% of water load excreted, P < 0.001). To clarify the mechanism of this impaired water excretion, we measured glomerular filtration rate (GFR), renal blood flow (RBF), and vasopressin (VP) levels. In cirrhosis, GFR was normal but RBF was decreased (4.5 vs 6.8 ml/min/g, P < 0.01). VP levels were found to be higher in cirrhotic rats (1.61 vs. 0.71 pg/ml, P < 0.025). The significance of the impaired renal hemodynamics and the increase in VP was assessed by inducing cirrhosis in VP-free Brattle-boro (diabetes insipidus; DI) rats. Despite histologic, biochemical, and renal hemodynamic changes that were comparable to cirrhotic rats with an intact neurohypophysis, cirrhotic DI rats had no impairment in water excretion. To determine the cause of increased VP in experimental cirrhosis, we determined blood volume and systemic hemodynamics. Although plasma volume was greater in experimental cirrhosis (4.3 vs. 3.0 ml/100 g, P < 0.05), cirrhotic rats had a significantly lower peripheral resistance (0.37 vs. 0.42mm Hg/ml/min/kg, P < 0.05) and mean arterial pressure (104 vs. 120mm Hg, P < 0.001) than did control rats. These results document that experimental cirrhosis in the rat is associated with impaired renal water excretion in association with both abnormal renal hemodynamics and increased VP levels. The impaired water excretion, however, is solely VP mediated. The nonosmolar stimulus for VP release may be due to abnormal systemic hemodynamics.Rôle de la vasopressine dans l'altération de l'excrétion de l'eau par le rat conscient atteint de cirrhose expérimentale. Cette étude a été entreprise pour élucider le mécanisme de l'altération de l'excrétion de l'eau au cours de la cirrhose du rat. Des rats conscients chez lesquels une cirrhose prouvée histologiquement a été induite par le tétrachlorure et le phénobarbital ont été comparés à des rats contrôles recevant seulement le phénobarbital. L'altération de l'excrétion de l'eau dans la cirrhose expérimentale a été vérifiée par l'hyponatrémie basale (138 vs. 147 mEq/litre, P < 0,005) et le défaut d'excrétion d'une charge en eau (osmolalité urinaire minimale 262 vs. 100 mOsm/kg; 58 vs. 102% de la charge d'eau sont excrétés, P < 0,001). Pour élucider le mécanisme de cette altération de l'excrétion de l'eau le débit de filtration glomérulaire (GFR), le débit sanguin rénal (RBF) et les concentrations de vasopressine (VP) ont été mesurés. Dans la cirrhose GFR est normal alors que RBF est diminué (4,5 vs. 6,8 ml/min/gm, P < 0,01). VP est plus élevée chez les rats cirrhotiques (1,61 vs. 0,71 pg/ml, P < 0,025). La signification des modifications de l'hémodynamique rénale et de l'augmentation de VP a été évaluée en créant des cirrhoses chez des rats sans VP de la souche Brattleboro (DI). Malgré des modifications histologiques, biochimiques et hémodynamiques rénales qui sont comparables à celles des rats dont la neurohypophyse est intacte, les rats DI cirrhotiques n'ont pas d'altération de l'excrétion de l'eau. Pour connaître la cause de l'augmentation de VP dans la cirrhose expérimentale le volume sanguin et l'hémodynamique systémique ont été étudiés. Quoique le volume plasmatique soit augmenté dans la cirrhose expérimentale (4,3 vs. 3,0 ml/100 g, P < 0,05) les rats cirrhotiques ont des résistances périphériques inférieures (0,37 vs. 0,42mm Hg/ml/min/kg, P < 0,05) et une pression artérielle moyenne inférieure (104 vs. 120mm Hg, P < 0,001) à celles des rats contrôles. Ces résultats indiquent que la cirrhose expérimentale du rat comporte une altération de l'excrétion de l'eau associée à une hémodynamique rénale anormale et à des concentrations de VP augmentées. L'altération de l'excrétion de l'eau, cependant, a la vasopressione comme seul médiateur. Le stimulus non osmolaire de la libération de VP pourrait être l'anomalie de l'hémodynamique systémique

The role of the Cucumber mosaic virus 2b protein in viral movement and symptom induction

The Cucumber mosaic virus (CMV) 2b protein is a counter-defense factor and symptom determinant. Conserved domains in the 2b protein sequence were mutated in the 2b gene of strain Fny-CMV. The effects of these mutations were assessed by infection of Nicotiana tabacum, N. benthamiana, and Arabidopsis thaliana (ecotype Col-0) with mutant viruses and by expression of mutant 2b transgenes in A. thaliana. We confirmed that two nuclear localization signals were required for symptom induction and found that the N-terminal domain was essential for symptom induction. The C-terminal domain and two serine residues within a putative phosphorylation domain modulated symptom severity. Further infection studies were conducted using Fny-CMVΔ2b, a mutant that cannot express the 2b protein and that induces no symptoms in N. tabacum, N. benthamiana, or A. thaliana ecotype Col-0. Surprisingly, in plants of A. thaliana ecotype C24, Fny-CMVΔ2b induced severe symptoms similar to those induced by the wild-type virus. However, C24 plants infected with the mutant virus recovered from disease while those infected with the wild-type virus did not. Expression of 2b transgenes from either Fny-CMV or from LS-CMV (a mild strain) in Col-0 plants enhanced systemic movement of Fny-CMVΔ2b and permitted symptom induction by Fny-CMVΔ2b. Taken together, the results indicate that the 2b protein itself is an important symptom determinant in certain hosts. However, they also suggest that the protein may somehow synergize symptom induction by other CMV-encoded factors