1,127 research outputs found
The Tournament Careers of Top-Ranked Men and Women Tennis Professionals: Are the Gentlemen More Committed than the Ladies?
We ask whether top-ranked male tennis professionals are more dedicated or committed to their careers than the top-ranked female professionals. We find no evidence that this is the case in the 1979-1994period. Despite substantially lower real earnings, the women pros competed for as many years as did the men and just as intensely in terms of annual number of tournaments played
The relationship between recalled self-esteem as a child and current levels of professional burnout among Anglican clergy in England
This study links and tests three strands of theory concerned with explaining individual differences in levels of professional burnout in general and among religious professionals in particular. These three strands concern the significance of current self-esteem, recalled self-esteem as a child, and personality. Data were provided by a sample of 1,278 male stipendiary parochial clergy working in the Church of England who completed the modified Maslach Burnout Inventory (specially designed for use among clergy), and the short-form Revised Eysenck Personality Questionnaire (designed to measure the personality dimensions of extraversion, neuroticism and psychoticism), together with a semantic differential index of recalled self-esteem as a child. The bivariate correlation coefficients demonstrated significant associations between more positive self-esteem as a child and lower levels of professional burnout (higher personal accomplishment, lower emotional exhaustion and lower depersonalisation). The bivariate correlation coefficients also demonstrated significant associations between personality and professional burnout. Multiple regression analyses, however, demonstrated that the association between recalled self-esteem as a child and professional burnout largely disappeared after controlling for the personality variables. The conclusion is drawn that knowledge about the personality profile of clergy functions as a more secure predictor of susceptibility to professional burnout than knowledge about recalled self-esteem as a child
Stock Cove, Trinity Bay : the Dorset Eskimo occupation of Newfoundland from a southeastern perspective
The Dorset Eskimo culture has been a subject of archaeological research in Newfoundland for more than five decades. Sites were first recognized by W.J. Wintemberg and Diamond Jenness in the late 1920's, after the original definition of Cape Dorset culture in the Arctic by the latter researcher, and since then numerous other finds have been made and excavations performed. Since the time of the first Dorset research in Newfoundland there has not been, however, a consistent interest in Dorset Eskimo archaeology. Instead, it has experienced a number of “hot and cold" periods, during which it was either in the forefront of Newfoundland research or of little concern to archaeologists. -- Two major monographs stand as landmarks in the history of Newfoundland Dorset archaeology. “The Cultural Affinities of the Newfoundland Dorset Eskimo" (Elmer Harp Jr. 1964), compiled following fieldwork in 1949 and 1950, examined the occupation of the northwestern Newfoundland coast, and compared and contrasted this Newfoundland Dorset complex with Dorset culture in Hudson Bay, northern Labrador, Baffin Island, and Greenland. Nearly two decades later, fieldwork by Urve Linnamae led to the publication of "The Dorset Culture: a Comparative Study in Newfoundland and the Arctic" (Urve Linnamae 1975). Both of these works have taken comparative approaches, and as a result there has developed the idea that Newfoundland Dorset is in some ways unique, in part due to the insular nature of the region. Concurrent with this idea arose the concept of "typical" Newfoundland Dorset culture, which implied a commonality of Dorset culture - or the observable part of Dorset culture, namely stone tools - throughout Newfoundland. -- Through the 1970's and 1980’s the pace of Dorset archaeology quickened, as several excavations were performed in northern, eastern, southern, and western Newfoundland. This work permits a more detailed examination of Newfoundland Dorset culture than was previously possible, and it has become increasingly obvious that considerable variety, with respect to settlement, subsistence, and artifact styles, existed among the Newfoundland Dorset population. -- This study presents data from the Dorset Eskimo site at Stock Cove, Trinity Bay, where excavations were carried out in 1981. Contrasts between the stock Cove assemblage, and northern and western Newfoundland Dorset assemblages are notable, as are ecological differences between southern, northern, and western regions of the island. The hypothetical scheme presented in the last chapter suggests that there were at least three regional Dorset populations in Newfoundland, each adapted to local conditions, and distinctive with regards to subsistence and settlement, lithic material utilization, and the style of at least one artifact type, the harpoon endblade
Constitutional Law
The authors survey the recent developments in Florida constitutional law, focusing on the powers and duties of the three branches of state government. Their discussion includes an analysis of the recent constitutional amendment modifying the jurisdiction of the supreme court
Structural requirements for glycosaminoglycan recognition by the Lyme disease spirochete, Borrelia burgdorferi
Borrelia burgdorferi, the Lyme disease agent, binds glycosaminoglycans (GAGs) such as heparin, heparan sulfate, and dermatan sulfate. Heparin or heparan sulfate fractions separated by size or charge were tested for their ability to inhibit attachment of B. burgdorferi to Vero cells. GAG chains of increasing length and/or charge showed increasing inhibitory potency, and detectable heparin inhibition of bacterial binding required a minimum of 16 residues. The ability of a given heparin fraction to inhibit binding to Vero cells was strongly predictive of its ability to inhibit hemagglutination, suggesting that hemagglutination reflects the capacity of B. burgdorferi to bind to GAGs
Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model.
BackgroundToca 511 (vocimagene amiretrorepvec) is a retroviral replicating vector encoding an optimized yeast cytosine deaminase (CD). Tumor-selective expression of CD converts the prodrug, 5-fluorocytosine (5-FC), into the active chemotherapeutic, 5-fluorouracil (5-FU). This therapeutic approach is being tested in a randomized phase II/III trial in recurrent glioblastoma and anaplastic astrocytoma (NCT0241416). The aim of this study was to identify the immune cell subsets contributing to antitumor immune responses following treatment with 5-FC in Toca 511-expressing gliomas in a syngeneic mouse model.MethodsFlow cytometry was utilized to monitor and characterize the immune cell infiltrate in subcutaneous Tu-2449 gliomas in B6C3F1 mice treated with Toca 511 and 5-FC.ResultsTumor-bearing animals treated with Toca 511 and 5-FC display alterations in immune cell populations within the tumor that result in antitumor immune protection. Attenuated immune subsets were exclusive to immunosuppressive cells of myeloid origin. Depletion of immunosuppressive cells temporally preceded a second event which included expansion of T cells which were polarized away from Th2 and Th17 in the CD4+ T cell compartment with concomitant expansion of interferon gamma-expressing CD8+ T cells. Immune alterations correlated with clearance of Tu-2449 subcutaneous tumors and T cell-dependent protection from future tumor challenge.ConclusionsTreatment with Toca 511 and 5-FC has a concentrated effect at the site of the tumor which causes direct tumor cell death and alterations in immune cell infiltrate, resulting in a tumor microenvironment that is more permissive to establishment of a T cell mediated antitumor immune response
Working out abjection in the Panapompom bêche-de-mer fishery: Race, economic change and the future in Papua New Guinea
This is the accepted version of the following article: Rollason, W. (2010), Working out abjection in the
Panapompom bêche-de-mer fishery: Race, economic change and the future in Papua New Guinea. The Australian
Journal of Anthropology, 21: 149–170. doi: 10.1111/j.1757-6547.2010.00076.x, which has been published in final
form at http://onlinelibrary.wiley.com/doi/10.1111/j.1757-6547.2010.00076.x/abstract.This is a paper about how men from Panapompom, an island in Milne Bay Province of Papua New Guinea (PNG), understand how they relate to white people and imagine the future. Until recently, men from Panapompom understood themselves to be engaged in a project of ‘development’, in which they would become more and more similar to white people. This was a desirable future. However, changes in the way Panapompom men work for money have resulted in a very different imagination of the future—one in which Panapompom people are not getting whiter, but blacker, and hence more and more excluded from the lives to which they aspire. Men now dive for bêche-de-mer, work which they regard as being particularly hard and dangerous. Diving has profound effects on the skin, blackening and hardening it, leading Panapompom men to liken themselves to the machines that create the wealth that white people use. These ‘mechanising’ effects that diving has on the black body lead men to see white people as the sole beneficiaries of the bêche-de-mer industry, and black people as mere tools or extensions. For bêche-de-mer divers, value and desired forms of life are lodged in Australia, Europe or America, while they find themselves excluded from this future by their growing blackness.ESR
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