Efficiency of carotine-chlorophyllic complexes use in a-hypovitaminosis of poultry

The principal purpose of this study was to investigate the possibility of using chloroprenol as a vitamin supplement in diets of broiler chickens for the prevention of A-vitamin deficiencies and improve the commercial quality of poultry products. In accordance with desired goal we have estimated the clinical-biochemical status of the broiler chickens under production-line conditions, defined the optimal dosages of chloroprenol for the broiler chicken, determined the effect of the drug on the morphological and biochemical parameters of blood, studied their effect on the natural resistance parameters of the body, accumulation of biological active substances in the liver, viability and productivit

Cinética de pós precursores de moagem para materiais piezocerâmicos baseados em sistemas de potássio e de noibato de sódio

One the main issues in the chemical engineering is to evaluate the grinding procedure powders for pizoceramic materals, which has gained attention in industry with valuables applications. It was demonstrated that the grinding of precursor powders for the PCM synthesis based on sodium and potassium niobates can be carried out using both spherical, and planetary mill. However, this process for niobium oxide is the most efficient if a planetary mill is used.: The coarse grinding should be carried out in a fluid medium, thereby typical dimension of grinding bodies should be decreased with decreasing powder size. Thus, by means of two sets of grinding bodies having a size of 6mm and 2mm it was possible to produce Nb2O5 powder with a mean particle size of about 1μm. The use of an ultrasonic disperser at the final stage of grinding makes it possible to disperse about 5 % wt. of nanoparticles. This significantly increases the specific surface area of these components substantively affecting their reactive activity.Uno de los principales problemas en la ingeniería química es evaluar los polvos de procedimiento de molienda para materiales de pizocerámica, que han ganado atención en la industria con aplicaciones valiosas. Se demostró que la trituración de polvos precursores para la síntesis de PCM basada en niobatos de sodio y potasio se puede llevar a cabo utilizando molinos esféricos y planetarios. Sin embargo, este proceso para el óxido de niobio es el más eficiente si se usa un molino planetario. La molienda gruesa debe llevarse a cabo en un medio fluido, por lo que la dimensión típica de los cuerpos de molienda debe disminuirse al disminuir el tamaño del polvo. Así, por medio de dos conjuntos de cuerpos de molienda que tienen un tamaño de 6 mm y 2 mm, fue posible producir polvo de Nb2O5 con un tamaño de partícula medio de aproximadamente 1 μm. El uso de un dispersor ultrasónico en la etapa final de la molienda permite dispersar alrededor del 5% en peso. de nanopartículas. Esto aumenta significativamente el área de superficie específica de estos componentes que afectan sustancialmente su actividad reactiva.Uma das principais questões da engenharia química é avaliar o processo de moagem pós para materiais pizocerâmicos, que tem ganhado destaque na indústria com aplicações valiosas. Foi demonstrado que a moagem de pós precursores para a síntese de PCM baseada em niobatos de sódio e potássio pode ser realizada usando moinhos esféricos e planetários. No entanto, este processo para óxido de nióbio é o mais eficiente se um moinho planetário é utilizado.: A moagem grossa deve ser realizada em um meio fluido, assim dimensão típica de corpos de moagem deve ser diminuída com a diminuição do tamanho do pó. Assim, por meio de dois conjuntos de corpos de moagem com um tamanho de 6 mm e 2 mm, foi possível produzir Nb2O5 em pó com um tamanho médio de partícula de cerca de 1 μm. O uso de um dispersor ultrassônico no estágio final de moagem possibilita dispersar cerca de 5% em peso. de nanopartículas. Isso aumenta significativamente a área de superfície específica desses componentes afetando substancialmente sua atividade reativa

The research of abnormal toxicity and local irritant effect in the Draize test of the drug furacilin, concentrate for the preparation of a solution for local and externaluse

The research of abnormal toxicity and locally irritating effect of the drug Furacilin, concentrate for the preparation of a solution for local and external use in comparison with the drug Furacilin, tablets for the preparation of the solution, was carried ou

Study of the selective phenolic inhibitors of arginase 2 acute toxicity

We have previously shown that the isolated arginase 2 inhibitors have a pronounced endothelioprotective level. A strategy is proposed for the targeted search for isolated arginase 2 inhibitors among compounds of a phenolic nature. Received 3 compounds, isolated arginase inhibitors 2. As a result of the study, the acute toxicity of the compounds obtained was studie

Calculation of mutual information for nonlinear communication channel at large signal-to-noise ratio

Using the path-integral technique we examine the mutual information for the communication channel modeled by the nonlinear Schrödinger equation with additive Gaussian noise. The nonlinear Schrödinger equation is one of the fundamental models in nonlinear physics, and it has a broad range of applications, including fiber optical communications - the backbone of the internet. At large signal-to-noise ratio we present the mutual information through the path-integral, which is convenient for the perturbative expansion in nonlinearity. In the limit of small noise and small nonlinearity we derive analytically the first nonzero nonlinear correction to the mutual information for the channel

Radiative Corrections to QCD Amplitudes in Quasi-Multi-Regge Kinematics

Radiative corrections to QCD amplitudes in the quasi-multi-Regge kinematics are interesting in particular since the Reggeized form of these amplitudes is used in the derivation of the NLO BFKL. This form is a hypothesis which must be at least carefully checked, if not proved. We calculate the radiative corrections in the one-loop approximation using the s-channel unitarity. Compatibility of the Reggeized form of the amplitudes with the s-channel unitarity requires fulfillment of the set of nonlinear equations for the Reggeon vertices. We show that these equations are satisfied.Comment: 28 pages,3 figure

Digital receivers for low-frequency radio telescopes UTR-2, URAN, GURT

This paper describes digital radio astronomical receivers used for decameter and meter wavelength observations. This paper describes digital radio astronomical receivers used for decameter and meter wavelength observations. Since 1998, digital receivers performing on-the-fly dynamic spectrum calculations or waveform data recording without data loss have been used at the UTR-2 radio telescope, the URAN VLBI system, and the GURT new generation radio telescope. Here we detail these receivers developed for operation in the strong interference environment that prevails in the decameter wavelength range. Data collected with these receivers allowed us to discover numerous radio astronomical objects and phenomena at low frequencies, a summary of which is also presented.Comment: 24 pages, 15 figure

Selecting the right therapeutic target for kidney disease

Kidney disease is a complex disease with several different etiologies and underlying associated pathophysiology. This is reflected by the lack of effective treatment therapies in chronic kidney disease (CKD) that stop disease progression. However, novel strategies, recent scientific breakthroughs, and technological advances have revealed new possibilities for finding novel disease drivers in CKD. This review describes some of the latest advances in the field and brings them together in a more holistic framework as applied to identification and validation of disease drivers in CKD. It uses high-resolution ‘patient-centric’ omics data sets, advanced in silico tools (systems biology, connectivity mapping, and machine learning) and ‘state-of-the-art‘ experimental systems (complex 3D systems in vitro, CRISPR gene editing, and various model biological systems in vivo). Application of such a framework is expected to increase the likelihood of successful identification of novel drug candidates based on strong human target validation and a better scientific understanding of underlying mechanisms

Impact of Flavonoids on Cellular and Molecular Mechanisms Underlying Age-Related Cognitive Decline and Neurodegeneration

Purpose of Review This review summarises the most recent evidence regarding the effects of dietary flavonoids on age-related cognitive decline and neurodegenerative diseases. Recent Findings Recent evidence indicates that plant-derived flavonoids may exert powerful actions on mammalian cognition and protect against the development of age-related cognitive decline and pathological neurodegeneration. The neuroprotective effects of flavonoids have been suggested to be due to interactions with the cellular and molecular architecture of brain regions responsible for memory. Summary Mechanisms for the beneficial effects of flavonoids on age-related cognitive decline and dementia are discussed, including modulating signalling pathways critical in controlling synaptic plasticity, reducing neuroinflammation, promoting vascular effects capable of stimulating new nerve cell growth in the hippocampus, bidirectional interactions with gut microbiota and attenuating the extracellular accumulation of pathological proteins. These processes are known to be important in maintaining optimal neuronal function and preventing age-related cognitive decline and neurodegeneration

National identity predicts public health support during a global pandemic

Changing collective behaviour and supporting non-pharmaceutical interventions is an important component in mitigating virus transmission during a pandemic. In a large international collaboration (Study 1, N = 49,968 across 67 countries), we investigated self-reported factors associated with public health behaviours (e.g., spatial distancing and stricter hygiene) and endorsed public policy interventions (e.g., closing bars and restaurants) during the early stage of the COVID-19 pandemic (April-May 2020). Respondents who reported identifying more strongly with their nation consistently reported greater engagement in public health behaviours and support for public health policies. Results were similar for representative and non-representative national samples. Study 2 (N = 42 countries) conceptually replicated the central finding using aggregate indices of national identity (obtained using the World Values Survey) and a measure of actual behaviour change during the pandemic (obtained from Google mobility reports). Higher levels of national identification prior to the pandemic predicted lower mobility during the early stage of the pandemic (r = -0.40). We discuss the potential implications of links between national identity, leadership, and public health for managing COVID-19 and future pandemics