209 research outputs found
Corrigendum: Calcium in Kenyon Cell Somata as a Substrate for an Olfactory Sensory Memory in Drosophila
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What are the social outcomes of climate policies? A systematic map and review of the ex-post literature
It is critical to ensure climate and energy policies are just, equitable and beneficial for communities, both to sustain public support for decarbonisation and address multifaceted societal challenges. Our objective in this article is to examine the diverse social outcomes that have resulted from climate policies, in varying contexts worldwide, over the past few decades. We review 203 ex-post climate policy assessments that analyse social outcomes in the literature. We systematically and comprehensively map out this work, identifying articles on carbon, energy and transport taxes, feed-in-tariffs, subsidies, direct procurement policies, large renewable deployment projects, and other regulatory and market-based interventions. We code each article in terms of their studied social outcomes and effects, with a focus on electricity access, energy affordability, community cohesion, employment, distributional and equity issues, livelihoods and poverty, procedural justice, subjective well-being and drudgery. Our analysis finds that climate and energy policies often fall short of delivering positive social outcomes. Nonetheless, across country contexts and policy types there are manifold examples of climate policymaking that does deliver on both social and climate goals. This requires attending to distributive and procedural justice in policy design, and making use of appropriate mechanisms to ensure that policy costs and benefits are fairly shared. We emphasize the need to further advance ex-post policy assessments and learn about what policies work for a just transition
Calcium in Kenyon Cell Somata as a Substrate for an Olfactory Sensory Memory in Drosophila
Animals can form associations between temporally separated stimuli. To do so, the nervous system has to retain a neural representation of the first stimulus until the second stimulus appears. The neural substrate of such sensory stimulus memories is unknown. Here, we search for a sensory odor memory in the insect olfactory system and characterize odorant-evoked Ca2+ activity at three consecutive layers of the olfactory system in Drosophila: in olfactory receptor neurons (ORNs) and projection neurons (PNs) in the antennal lobe, and in Kenyon cells (KCs) in the mushroom body. We show that the post-stimulus responses in ORN axons, PN dendrites, PN somata, and KC dendrites are odor-specific, but they are not predictive of the chemical identity of past olfactory stimuli. However, the post-stimulus responses in KC somata carry information about the identity of previous olfactory stimuli. These findings show that the Ca2+ dynamics in KC somata could encode a sensory memory of odorant identity and thus might serve as a basis for associations between temporally separated stimuli
Corrigendum: Calcium in Kenyon Cell Somata as a Substrate for an Olfactory Sensory Memory in Drosophila (vol 12, 2018)
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What are the social outcomes of climate policies? A systematic map and review of the ex-post literature
It is critical to ensure climate and energy policies are just, equitable and beneficial for communities, both to sustain public support for decarbonisation and address multifaceted societal challenges. Our objective in this article is to examine the diverse social outcomes that have resulted from climate policies, in varying contexts worldwide, over the past few decades. We review 203 ex-post climate policy assessments that analyse social outcomes in the literature. We systematically and comprehensively map out this work, identifying articles on carbon, energy and transport taxes, feed-in-tariffs, subsidies, direct procurement policies, large renewable deployment projects, and other regulatory and market-based interventions. We code each article in terms of their studied social outcomes and effects, with a focus on electricity access, energy affordability, community cohesion, employment, distributional and equity issues, livelihoods and poverty, procedural justice, subjective well-being and drudgery. Our analysis finds that climate and energy policies often fall short of delivering positive social outcomes. Nonetheless, across country contexts and policy types there are manifold examples of climate policymaking that does deliver on both social and climate goals. This requires attending to distributive and procedural justice in policy design, and making use of appropriate mechanisms to ensure that policy costs and benefits are fairly shared. We emphasize the need to further advance ex-post policy assessments and learn about what policies work for a just transition
The annealing mechanism of AuGe/Ni/Au ohmic contacts to a two-dimensional electron gas in GaAs/AlGaAs heterostructures
Ohmic contacts to a two-dimensional electron gas (2DEG) in GaAs/AlGaAs
heterostructures are often realized by annealing of AuGe/Ni/Au that is
deposited on its surface. We studied how the quality of this type of ohmic
contact depends on the annealing time and temperature, and how optimal
parameters depend on the depth of the 2DEG below the surface. Combined with
transmission electron microscopy and energy-dispersive X-ray spectrometry
studies of the annealed contacts, our results allow for identifying the
annealing mechanism and proposing a model that can predict optimal annealing
parameters for a certain heterostructure.Comment: 9 pages, 4 figure
Two-dimensional finite element simulation of fracture and fatigue behaviours of alumina microstructures for hip prosthesis
This paper describes a two-dimensional (2D) finite element simulation for
fracture and fatigue behaviours of pure alumina microstructures such as those
found at hip prostheses. Finite element models are developed using actual Al2O3
microstructures and a bilinear cohesive zone law. Simulation conditions are
similar to those found at a slip zone in a dry contact between a femoral head
and an acetabular cup of hip prosthesis. Contact stresses are imposed to
generate cracks in the models. Magnitudes of imposed stresses are higher than
those found at the microscopic scale. Effects of microstructures and contact
stresses are investigated in terms of crack formation. In addition, fatigue
behaviour of the microstructure is determined by performing simulations under
cyclic loading conditions. It is shown that crack density observed in a
microstructure increases with increasing magnitude of applied contact stress.
Moreover, crack density increases linearly with respect to the number of
fatigue cycles within a given contact stress range. Meanwhile, as applied
contact stress increases, number of cycles to failure decreases gradually.
Finally, this proposed finite element simulation offers an effective method for
identifying fracture and fatigue behaviours of a microstructure provided that
microstructure images are available
Analgesia epidural com clonidina ou romifidina em cães submetidos à cirurgia coxofemoral
Telocytes and putative stem cells in the lungs: electron microscopy, electron tomography and laser scanning microscopy
This study describes a novel type of interstitial (stromal) cell — telocytes (TCs) — in the human and mouse respiratory tree (terminal and respiratory bronchioles, as well as alveolar ducts). TCs have recently been described in pleura, epicardium, myocardium, endocardium, intestine, uterus, pancreas, mammary gland, etc. (see www.telocytes.com). TCs are cells with specific prolongations called telopodes (Tp), frequently two to three per cell. Tp are very long prolongations (tens up to hundreds of μm) built of alternating thin segments known as podomers (≤ 200 nm, below the resolving power of light microscope) and dilated segments called podoms, which accommodate mitochondria, rough endoplasmic reticulum and caveolae. Tp ramify dichotomously, making a 3-dimensional network with complex homo- and heterocellular junctions. Confocal microscopy reveals that TCs are c-kit- and CD34-positive. Tp release shed vesicles or exosomes, sending macromolecular signals to neighboring cells and eventually modifying their transcriptional activity. At bronchoalveolar junctions, TCs have been observed in close association with putative stem cells (SCs) in the subepithelial stroma. SCs are recognized by their ultrastructure and Sca-1 positivity. Tp surround SCs, forming complex TC-SC niches (TC-SCNs). Electron tomography allows the identification of bridging nanostructures, which connect Tp with SCs. In conclusion, this study shows the presence of TCs in lungs and identifies a TC-SC tandem in subepithelial niches of the bronchiolar tree. In TC-SCNs, the synergy of TCs and SCs may be based on nanocontacts and shed vesicles
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