ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

The Allergic Rhinitis and its Impact on Asthma (ARIA) initiative commenced during a World Health Organization workshop in 1999. The initial goals were (1) to propose a new allergic rhinitis classification, (2) to promote the concept of multi-morbidity in asthma a

Detectable clonal mosaicism and its relationship to aging and cancer

In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide association studies, we observed large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples. We observed mosaic abnormalities, either aneuploidy or copy-neutral loss of heterozygosity, of >2 Mb in size in autosomes of 517 individuals (0.89%), with abnormal cell proportions of between 7% and 95%. In cancer-free individuals, frequency increased with age, from 0.23% under 50 years to 1.91% between 75 and 79 years (P = 4.8 × 10(-8)). Mosaic abnormalities were more frequent in individuals with solid tumors (0.97% versus 0.74% in cancer-free individuals; odds ratio (OR) = 1.25; P = 0.016), with stronger association with cases who had DNA collected before diagnosis or treatment (OR = 1.45; P = 0.0005). Detectable mosaicism was also more common in individuals for whom DNA was collected at least 1 year before diagnosis with leukemia compared to cancer-free individuals (OR = 35.4; P = 3.8 × 10(-11)). These findings underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases

IC compatible MEMS technology

This paper deals with an Integrated Circuits (ICs) compatible MEMS technology, which is used to elaborate an ultra compact RF communication module centered at 24GHz. This technology uses conventional equipments and is in adequation with millimeterwave applications. A compatibility test protocol has consequently been defined in order to check that each technological step does not degrade the SiGe circuits’ performances. Finally, the realized demonstrator present a total surface of only 9mm²

ALCANT - Aktive steuerbare Antenne fuer Satellitenkommunikation zu mobilen und ortsfesten Nutzern Schlussbericht

SIGLEAvailable from TIB Hannover: F04B151+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung und Forschung, Berlin (Germany)DEGerman

A Multivariate Multilevel Approach to the Modeling of Accuracy and Speed of Test Takers

speed, accuracy, IRT, response times,

Vocational and working career of asthmatic adolescents is only slightly affected.

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