554 research outputs found
An Obstruction to Quantization of the Sphere
In the standard example of strict deformation quantization of the symplectic
sphere , the set of allowed values of the quantization parameter
is not connected; indeed, it is almost discrete. Li recently constructed a
class of examples (including ) in which can take any value in an
interval, but these examples are badly behaved. Here, I identify a natural
additional axiom for strict deformation quantization and prove that it implies
that the parameter set for quantizing is never connected.Comment: 23 page. v2: changed sign conventio
Dynamic regulation of Ero1 and peroxiredoxin 4 localization in the secretory pathway
In the early secretory compartment (ESC), a network of chaper-
ones and enzymes assists oxidative folding of nascent proteins.
Ero1 flavoproteins oxidize protein disulfide isomerase (PDI), gen-
erating H2O2 as a byproduct. Peroxiredoxin 4 (Prx4) can utilize
luminal H2O2 to oxidize PDI, thus favoring oxidative folding while
limiting oxidative stress. Interestingly, neither ER oxidase contains
known ER retention signal(s), raising the question of how cells pre-
vent their secretion. Here we show that the two proteins share sim-
ilar intracellular localization mechanisms. Their secretion is pre-
vented by sequential interactions with PDI and ERp44, two
resident proteins of the ESC-bearing KDEL-like motifs. PDI binds
preferentially Ero1 , whereas ERp44 equally retains Ero1 and
Prx4. The different binding properties of Ero1 and Prx4 increase
the robustness of ER redox homeostasis
Two-magnon Raman scattering in spin-ladder geometries and the ratio of rung and leg exchange constants
We discuss ways in which the ratio of exchange constants along the rungs and
legs of a spin-ladder material influences the two-magnon Raman scattering
spectra and hence can be determined from it. We show that within the
Fleury-Loudon-Elliott approach, the Raman line-shape does not change with
polarization geometries. This lineshape is well known to be difficult to
calculate accurately from theory. However, the Raman scattering intensities do
vary with polarization geometries, which are easy to calculate. With some
assumptions about the Raman scattering Hamiltonian, the latter can be used to
estimate the ratio of exchange constants. We apply these results to Sugai's
recent measurements of Raman scattering from spin-ladder materials such as
LaCaCuO and SrCuO.Comment: 5 pages, revtex. Latest version focuses on ladder materials, with a
detailed examination of the role of Heisenberg-like coupling constants which
appear in the Fleury-Loudon-Elliott scattering operator but are rarely
discussed in the literatur
Direct perturbation theory on the shift of Electron Spin Resonance
We formulate a direct and systematic perturbation theory on the shift of the
main paramagnetic peak in Electron Spin Resonance, and derive a general
expression up to second order. It is applied to one-dimensional XXZ and
transverse Ising models in the high field limit, to obtain explicit results
including the polarization dependence for arbitrary temperature.Comment: 5 pages (no figures) in REVTE
Electron Spin Resonance in S=1/2 antiferromagnetic chains
A systematic field-theory approach to Electron Spin Resonance (ESR) in the
quantum antiferromagnetic chain at low temperature (compared to the
exchange coupling ) is developed. In particular, effects of a transverse
staggered field and an exchange anisotropy (including a dipolar
interaction) on the ESR lineshape are discussed. In the lowest order
of perturbation theory, the linewidth is given as and
, respectively. In the case of a transverse staggered
field, the perturbative expansion diverges at lower temperature;
non-perturbative effects at very low temperature are discussed using exact
results on the sine-Gordon field theory. We also compare our field-theory
results with the predictions of Kubo-Tomita theory for the high-temperature
regime, and discuss the crossover between the two regimes. It is argued that a
naive application of the standard Kubo-Tomita theory to the
Dzyaloshinskii-Moriya interaction gives an incorrect result. A rigorous and
exact identity on the polarization dependence is derived for certain class of
anisotropy, and compared with the field-theory results.Comment: 53 pages in REVTEX, 7 figures in EPS included; revised version with
missing references and correction
Non-universal equilibrium crystal shape results from sticky steps
The anisotropic surface free energy, Andreev surface free energy, and
equilibrium crystal shape (ECS) z=z(x,y) are calculated numerically using a
transfer matrix approach with the density matrix renormalization group (DMRG)
method. The adopted surface model is a restricted solid-on-solid (RSOS) model
with "sticky" steps, i.e., steps with a point-contact type attraction between
them (p-RSOS model). By analyzing the results, we obtain a first-order shape
transition on the ECS profile around the (111) facet; and on the curved surface
near the (001) facet edge, we obtain shape exponents having values different
from those of the universal Gruber-Mullins-Pokrovsky-Talapov (GMPT) class. In
order to elucidate the origin of the non-universal shape exponents, we
calculate the slope dependence of the mean step height of "step droplets"
(bound states of steps) using the Monte Carlo method, where p=(dz/dx,
dz/dy)$, and represents the thermal averag |p| dependence of , we
derive a |p|-expanded expression for the non-universal surface free energy
f_{eff}(p), which contains quadratic terms with respect to |p|. The first-order
shape transition and the non-universal shape exponents obtained by the DMRG
calculations are reproduced thermodynamically from the non-universal surface
free energy f_{eff}(p).Comment: 31 pages, 21 figure
Population genomics of yams: evolution and domestication of Dioscorea species
Published online: 21 Aug 2021Yam is a collective name of tuber crops belonging to the genus Dioscorea. Yam is important not only as a staple food crop but also as an integral component of society and culture of the millions of people who depend on it. However, due to its regional importance, yam has long been regarded as an “orphan crop” lacking a due global attention. Although this perception is changing with recent advances in genomics technologies, domestication processes of most yam species are still ambiguous. This is mainly due to the complicated evolutionary history of Dioscorea species caused by frequent hybridization and polyploidization, which is possibly caused by dioecy that imposed obligate outcrossing to the species of Dioscorea. In this chapter, we provide an overview of the evolution of Dioscorea and address the domestication of yam from population genomics perspectives by focusing on the processes of hybridization and polyploidization. A review is given to the recent population genomics studies on the hybrid origin of D. rotundata in West and Central Africa, the global dispersion of D. alata through human migrations, and the whole-genome duplication of the South America species of D. trifida. In the end, we give a summary of current understanding of sex-determination system in Dioscorea
First events from the CNGS neutrino beam detected in the OPERA experiment
The OPERA neutrino detector at the underground Gran Sasso Laboratory (LNGS)
was designed to perform the first detection of neutrino oscillations in
appearance mode, through the study of nu_mu to nu_tau oscillations. The
apparatus consists of a lead/emulsion-film target complemented by electronic
detectors. It is placed in the high-energy, long-baseline CERN to LNGS beam
(CNGS) 730 km away from the neutrino source. In August 2006 a first run with
CNGS neutrinos was successfully conducted. A first sample of neutrino events
was collected, statistically consistent with the integrated beam intensity.
After a brief description of the beam and of the various sub-detectors, we
report on the achievement of this milestone, presenting the first data and some
analysis results.Comment: Submitted to the New Journal of Physic
Effectiveness of interferon-beta and temozolomide combination therapy against temozolomide-refractory recurrent anaplastic astrocytoma
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