The status of Orobanche crenata in Sicily and preliminary observations on Orobanche crenata susceptibility in Vicia faba

Since more than 10 years we are recording Orobanche crenata populations variations and testing traditional remedies to assess their applicability in a low impact agriculture that may be applied also in developing countries. Starting from the observation that often in C Sicily dense fields of Broadbean show lower Broomrape infestation, we did some preliminary observations on Orobanche crenata susceptibility in Vicia faba var. faba and Vicia faba var. equina with different agricultural techniques. First results show a higher resistance of the latter sowed at higher densities

Gabriel Marcel (1889-1973). Narratore dell'io filosofico

A quarant\u2019anni dalla sua morte (1889-1973), questo saggio ricorda Gabriel Marcel, ripercorrendo il versante autobiografico della sua opera. In essa Marcel alza il velo sullo sfondo esperienziale su cui si stagliano i suoi scritti: ne emerge lo stile di una ricerca in costante dialogo con l\u2019esistenza, toccata da quella \u201cmorsure du r\ue9el\u201d che la apre alla \u2018filosofia concreta\u2019, a un racconto di s\ue9 in cui si intrecciano diversi ordini di realt\ue0: natura, libert\ue0 e grazia; tempo, storia ed eternit\ue0, nei loro profili di visibilit\ue0 e invisibilit\ue0, di realt\ue0 e finzione. L\u2019autobiografia di Marcel testimonia la strutturale relazionalit\ue0 del soggetto che coinvolge la riflessione etica, ontologica e religiosa contemporanea

NEW VARIETIES OF DURUM WHEAT (TRITICUM DURUM DESF.) IN SICILY: EVALUATION OF GENOTYPE-ENVIRONMENT INTERACTION

Durum wheat (Triticum durum Desf.) is the typical cereal crop in semi-arid Italian environments, and Sicily, is one of the regions of southern Italy where the cultivation of durum wheat is very spread. The thesis was the comparison of 14 genotypes of durum wheat located in 11 locations typical of the Sicilian cropland in the years 2006-2011. The analysis of the results has allowed to study the productive and qualitative behavior of the tested genotypes. In addition, the study of interaction genotype-environment, has allowed to verify the yield stability in quantity and the quality of the grain by the individual genotypes

Needs, expectations and consequences for the child growing up in a family with a parent with mental illness

Parental mental illness is considered one of the strongest risk-factors for development of offspring psychopathology. The lack of pan-European guidelines for empowering children of parents with mental illness led to EU project CAMILLE - Empowerment of Children and Adolescents of Mentally Ill Parents through Training of Professionals working with children and adolescents. The first task in this project, was to analyse needs, expectations and consequences for children, with respect to living with a parent with mental illness. The aim this paper is to report results of these analyses. The qualitative research was conducted in England, Finland, Germany, Italy, Norway, Poland and Scotland (N=96). There were 3 types of focus groups: (1) professionals (doctors, nurses, psychologists, social workers), (2) adult children and partners of a person with mental illness, (3) parents who have experienced mental illness during their parenthood. Framework analysis method was used. Results of the study highlighted that the main consequences for children of parental mental illness were role reversal, emotional and behavioural problems, lack of parent’s attention and stigma. The main needs of these children were emotional support, security and multidisciplinary help. Implications for practice are: (1) professionals working with parents with mental illness should be aware of the specific consequences for the children; (2) to empower children they should focus on them, but not excluding parents from the parental roles; (3) the multi-agency collaboration is necessary; (4) schools should provide counselling and teach staff and students about mental health problems to reduce stigm

Feasibility of a combined mobile-health electrocardiographic and rapid diagnostic test screening for chagas-related cardiac alterations

Background: Chronic Chagas cardiomyopathy (CChC) is the most common cause of death related to Chagas disease (CD). The aim of this study was to assess the feasibility of a combined rapid diagnostic test (RDT) and electrocardiographic (ECG) screening in a remote rural village of the Bolivian Chaco, with a high prevalence of CChC. Methods: Consecutive healthy volunteers > 15 years were enrolled in the community of Palmarito (municipality of Gutierrez, Santa Cruz Department, Bolivia) in February 2019. All patients performed an RDT with Chagas Stat-Pak(®) (CSP, Chembio Diagnostic System, Medford, NY, USA) and an ECG by D-Heart(®) technology, a low-cost, user-friendly smartphone-based 8-lead Bluetooth ECG. RDTs were read locally while ECGs were sent to a cardiology clinic which transmitted reports within 24 h from recording. Results: Among 140 people (54 men, median age 38(interquartile range 23–54) years), 98 (70%) were positive for Trypanosoma cruzi infection, with a linear, age-dependent, increasing trend (p < 0.001). Twenty-five (18%) individuals showed ECG abnormalities compatible with CD. Prevalence of ECG abnormalities was higher in infected individuals and was associated with higher systolic blood pressure and smoking. Following screening, 22 (16%) individuals underwent clinical evaluation and chest X-ray and two were referred for further evaluation. At multivariate analysis, positive CSP results (OR = 4.75, 95%CI 1.08–20.96, p = 0.039) and smoking (OR = 4.20, 95%CI 1.18–14.92, p = 0.027) were independent predictors of ECG abnormalities. Overall cost for screening implementation was <10 $. Conclusions: Combined mobile-Health and RDTs was a reliable and effective low-cost strategy to identify patients at high risk of disease needing cardiologic assessment suggesting potential future applications

Infliximab in patients with active ankylosing spondylitis: experience at Hospital Nacional Edgardo Rebagliati Martins

Infliximab es un medicamento efectivo en el tratamiento de pacientes con espondilitis anquilosante (EA) activa. Sin embargo, debido a su alto costo, su uso indiscriminado es prohibitivo. Objetivo: Evaluar si un régimen de inducción con infliximab es efectivo en pacientes con EA activa. Diseño: Sólo expuestos. Lugar: Servicio de Reumatología del Hospital Nacional Edgardo Rebagliati. Participantes: Pacientes con espondilitis anquilosante activa refractaria. Intervenciones: infliximab a las 0, 2 y 6 semanas. Un paciente recibió dosis de 3 mg/kg y los restantes 5 mg/kg de infliximab. Todos los pacientes continuaron recibiendo sulfasalazina. Principales medidas de resultados: Se determinó la proporción de pacientes que alcanzaron mejoría de acuerdo a los criterios ASAS 20, ASAS 40 y BASDAI 50, en la última evaluación (mediana de 55 semanas). Resultados: En la última evaluación, cinco pacientes (71,4%) presentaban respuesta ASAS 20 sostenida. Cuatro (57%) y tres (43%) de los pacientes alcanzaron BASDAI 50 y ASAS 40, respectivamente. Tres pacientes (43%) recayeron en un tiempo promedio de 26,6 semanas. No se observó efectos adversos serios. Conclusiones: La infusión de tres dosis de infliximab es efectiva para controlar la actividad de la enfermedad de los pacientes con EA refractaria a AINEs y en algunos pacientes controla la enfermedad por periodos prolongados de tiempo.Infliximab is effective in treating patients with ankylosing spondylitis (AS). However, its cost makes its indiscrimate use prohibitive. Objective: To determine whether an induction regimen with infliximab remained effective over time in a group of patients with active AS. Design: Exposed only. Setting: Rheumatology Service, Hospital Nacional Edgardo Rebagliati. Participants: Patients with active and refractory ankylosing spondylitis. Interventions: Infliximab, administered at weeks 0, 2 and 6. One patient received doses of 3 mg/kg and the remaining patients received 5 mg/kg of infliximab. All patients continued their treatment with sulfasalazine. Main outcome measures: We determined the proportion of patients achieving ASAS 20, ASAS 40 and Bath ankylosing spondylitis disease activity index - BASDAI 50 at last assessment (median of 55 weeks). Results: At last observation, five patients (71,4%) had a sustained ASAS 20 response. Four (57%) and three (43%) patients remained responders according to the BASDAI 50 and ASAS 40 respectively.Three patients (43%) relapsed, with mean time of 26,6 weeks. No serious adverse events were observed. Conclusions: The infusion of three doses of infliximab is effective to control disease activity in patients with refractory AS. In some patients, effectiveness remained for a prolonged period of time

Análisis del uso de los protocolos en Atención Primaria: opinión de Enfermería

Màster en Administració i Gestió en Cures d'Infermeria, Escola Universitarias Santa Madrona, Universitat de Barcelona. Any: 2001 Director: Esteve Pon

Intravenous pamidronate in refractory ankylosing spondylitis

Objetivo: Evaluar la terapia con pamidronato, en pacientes con espondilitis anquilosante (EA) activa, con respuesta subóptima o falla a los antiinflamatorios no-esteroideos (AINES) y sulfasalazina. Diseño: Estudio clínico comparativo. Lugar: Hospital Nacional Edgardo Rebagliati Martins, EsSalud, Lima, Perú. Participantes: Pacientes con espondilitis anquilosante. Intervenciones. Se incluyó 9 pacientes con EA (6 varones), con enfermedad activa (BASDAI ≥4), actividad axial y falta de respuesta a los Aines y sulfasalazina a dosis de 3g/d. Todos los pacientes recibieron 60 mg de pamidronato mensual, en infusión endovenosa, durante 6 meses, y continuaron tomando AINES y sulfasalazina. La mejoría clínica fue evaluada usando el Asas 20. En forma secundaria se evaluó el ASAS 40, BASDAI 50, BASDAI, BASFI Y BASMI, a las 24 y 48 semanas (32 a 86 semanas). La diferencia entre el índice de pre y postratamiento fue evaluada usando la prueba de Wilcoxon. Principales medidas de resultados: Evaluación del ASAS 20. Resultados. El 67% alcanzó un Asas 20 a las 24 semanas y 78% a las 48 semanas; 33,3% y 55,6% tuvieron ASAS 40 y 33,3%; y 44,4% alcanzó BASDAI 50 a las 24 y 48 semanas, respectivamente. Un paciente recayó a la semana 20. Tres pacientes (33,3%) permanecieron sin cambios. A las 24 y 48 semanas, la media de BASDAI disminuyó en 45,1% (p=0,007) y en 52,1% (p=0,01), la media de BASFI en 38,2% (p=0,007) y en 52,3% (p=0,007), y la media de BASMI en 39,2% (p=0,01) y 39,2% (p=0,01), respectivamente. Los eventos adversos no fueron importantes con esta terapia. Conclusiones. El tratamiento con pamidronato demostró ser efectivo en este grupo de pacientes con EA, refractaria a AINES y a sulfasalazina.Objective: To determine the response of an aminobisphosphonate (pamidronate) in patients with ankylosing spondylitis (AS) who had suboptimal or no response to nonsteroidal anti-inflammatory drugs (NSAIDs) and sulfasalazine. Design: Comparative clinical study. Setting: Hospital Nacional Edgardo Rebagliati Martins, EsSalud, Lima, Peru. Participants: Patients with ankylosing spondylitis. Intervenciones: Nine patients with AS (6 males), with active disease [BASDAI ≥4] and no response to NSAIDs and sulfasalazine up to 3g/day entered the study. All patients received monthly infusions of 60 mg of pamidronate for 6 months and remained taking NSAID and sulfasalazine. Clinical improvement was evaluated using the Assessments in Ankylosing Spondylitis 20 (ASAS 20). Secondary evaluations included ASAS 40, BASDAI 50, BASDAI, BASFI, and BASMI at 24 weeks and at last observation [48 weeks (32 to 86 weeks)]. Differences between pre and post treatment distributions of all continuous indices were evaluated using the Wilcoxon signed rank test. Main outcome measures: Evaluated of ASAS 20. Results: Sixty-seven percent achieved ASAS 20 at 24 weeks and 78% at 48 weeks; 33,3% and 55,6% achieved ASAS 40 at 24 and 48 weeks, respectively, and 33,3% and 44,4% achieved BASDAI 50 at weeks 24 and 48, respectively. One patient relapsed at week 20. In three patients (33,3%) the scores remained unchanged. At weeks 24 and 48 mean BASDAI decreased by 45,1% (p=0,007) and by 52,1% (p=0,01), mean BASFI decreased by 38,2% (p=0,007) and by 52,3% (p=0.007), and mean BASMI decreased by 39,2% (p=0,01) and 39,2% (p=0,01), respectively. There were no significant adverse events with this therapy. Conclusions: Our data provide further evidence of pamidronate therapy effectiveness in patients with AS who are refractory to NSAIDs and sulfasalazine

Conocimiento ecológico tradicional y conductas hacia la ecoeficiencia agrícola en pobladores de la provincia de Junín, Perú

La industrialización de la agricultura ha generado una producción a gran escala y en menor tiempo, originando daños ambientales, en muchos casos irreversibles. En este proceso se han&nbsp;utilizados diferentes insumos químicos y bioquímicos que han empobrecido la tierra,&nbsp;contaminado los productos agrícolas y afectando incluso la salud humana. Esta situación&nbsp;amerita una atención inmediata de los diferentes sectores de la sociedad, con el soporte del&nbsp;conocimiento científico. La investigación se enmarcó dentro de un enfoque intercultural,&nbsp;interdisciplinario y transversal teniendo como soporte la filosofía del desarrollo sostenible. El&nbsp;objetivo fue determinar la relación que existe entre el conocimiento ecológico tradicional y las&nbsp;conductas hacia la ecoeficiencia agrícola en pobladores de la provincia de Junín, Perú. Se&nbsp;formuló la hipótesis: existe una relación significativa entre el conocimiento ecológico&nbsp;tradicional y conductas hacia la ecoeficiencia agrícola en los pobladores de la provincia de&nbsp;Junín. La investigación fue de tipo básica, nivel descriptivo y diseño correlacional. Se utilizó la&nbsp;técnica de la encuesta, y como instrumentos los cuestionarios de conocimientos ecológicos&nbsp;tradicionales y de prácticas de ecoeficiencia agrícola, diseñadas y validadas por juicio de&nbsp;expertos y por el coeficiente de Spearman-Brown. La población estuvo conformada por&nbsp;pobladores de las 24 comunidades de la provincia de Junín, Perú. La muestra estuvo&nbsp;constituida por 210 sujetos, 60 damas y 150 varones. Los resultados obtenidos a partir del&nbsp;análisis estadístico evidencian una relación significativa entre el conocimiento ecológico&nbsp;tradicional y las conductas hacia la ecoeficiencia agrícola en pobladores de Junín, con 0.05 de&nbsp;significancia y τ = 0.587 y Z (1.87) &lt; Z (5.87)